EE9400356A - Polüetüleenglükool proteiin konjugaadid, ühendid, nende kasutamine, meetod konjugaatide valmistamiseks ja ravimvormid - Google Patents

Polüetüleenglükool proteiin konjugaadid, ühendid, nende kasutamine, meetod konjugaatide valmistamiseks ja ravimvormid

Info

Publication number
EE9400356A
EE9400356A EE9400356A EE9400356A EE9400356A EE 9400356 A EE9400356 A EE 9400356A EE 9400356 A EE9400356 A EE 9400356A EE 9400356 A EE9400356 A EE 9400356A EE 9400356 A EE9400356 A EE 9400356A
Authority
EE
Estonia
Prior art keywords
conjugates
polyethylene glycol
compounds
preparation
dosage forms
Prior art date
Application number
EE9400356A
Other languages
English (en)
Estonian (et)
Inventor
Hakimi John
Kilian Patricia
Rosen Perry
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27101069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE9400356(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of EE9400356A publication Critical patent/EE9400356A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/964—Chemistry: molecular biology and microbiology including enzyme-ligand conjugate production, e.g. reducing rate of nonproductive linkage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/816—Attached to the carrier via a bridging agent
EE9400356A 1991-03-25 1994-11-23 Polüetüleenglükool proteiin konjugaadid, ühendid, nende kasutamine, meetod konjugaatide valmistamiseks ja ravimvormid EE9400356A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67400191A 1991-03-25 1991-03-25
US07/767,000 US5595732A (en) 1991-03-25 1991-09-27 Polyethylene-protein conjugates

Publications (1)

Publication Number Publication Date
EE9400356A true EE9400356A (et) 1996-04-15

Family

ID=27101069

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9400356A EE9400356A (et) 1991-03-25 1994-11-23 Polüetüleenglükool proteiin konjugaadid, ühendid, nende kasutamine, meetod konjugaatide valmistamiseks ja ravimvormid

Country Status (32)

Country Link
US (7) US5595732A (el)
EP (1) EP0510356B1 (el)
JP (1) JP2637010B2 (el)
KR (1) KR920018079A (el)
CN (2) CN1038035C (el)
AT (1) ATE176159T1 (el)
AU (2) AU657311B2 (el)
BG (1) BG60800B2 (el)
BR (1) BR9201015A (el)
CA (1) CA2063886C (el)
CS (1) CS87192A3 (el)
CY (1) CY2169B1 (el)
DE (1) DE69228269T2 (el)
DK (1) DK0510356T3 (el)
EE (1) EE9400356A (el)
ES (1) ES2128329T3 (el)
FI (2) FI107927B (el)
GR (1) GR3030049T3 (el)
HU (2) HUT60512A (el)
IE (1) IE920936A1 (el)
IL (1) IL101348A0 (el)
IS (1) IS3824A (el)
MW (1) MW1892A1 (el)
MX (1) MX9201298A (el)
MY (1) MY131095A (el)
NO (1) NO921142L (el)
NZ (2) NZ248022A (el)
OA (1) OA09760A (el)
RO (1) RO109543B1 (el)
SI (1) SI9210294A (el)
ZA (1) ZA922110B (el)
ZW (1) ZW4392A1 (el)

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CA2063886C (en) 2002-08-20
NZ242084A (en) 1993-12-23
IL101348A0 (en) 1992-11-15
JPH05117300A (ja) 1993-05-14
RO109543B1 (ro) 1995-03-30
CY2169B1 (en) 2002-08-23
FI20011554A (fi) 2001-07-17
DE69228269T2 (de) 1999-07-08
DE69228269D1 (de) 1999-03-11
KR920018079A (ko) 1992-10-21
US5559213A (en) 1996-09-24
EP0510356B1 (en) 1999-01-27
ZW4392A1 (en) 1992-09-23
JP2637010B2 (ja) 1997-08-06
FI107927B (fi) 2001-10-31
NZ248022A (en) 1993-12-23
CN1038035C (zh) 1998-04-15
HU211945A9 (en) 1996-01-29
US5792834A (en) 1998-08-11
OA09760A (fr) 1993-11-30
ZA922110B (en) 1992-11-25
US5747646A (en) 1998-05-05
FI921267A (fi) 1992-09-26
US5834594A (en) 1998-11-10
DK0510356T3 (da) 1999-09-13
AU657311B2 (en) 1995-03-09
CN1175465A (zh) 1998-03-11
IS3824A (is) 1992-09-26
HUT60512A (en) 1992-09-28
GR3030049T3 (en) 1999-07-30
IE920936A1 (en) 1992-10-07
CS87192A3 (en) 1992-10-14
ATE176159T1 (de) 1999-02-15
AU1316092A (en) 1992-10-01
NO921142L (no) 1992-09-28
CA2063886A1 (en) 1992-09-26
ES2128329T3 (es) 1999-05-16
MX9201298A (es) 1992-10-01
NO921142D0 (no) 1992-03-24
BG60800B2 (bg) 1996-03-29
FI921267A0 (fi) 1992-03-24
BR9201015A (pt) 1992-11-24
MY131095A (en) 2007-07-31
AU7761594A (en) 1995-01-12
US5849860A (en) 1998-12-15
EP0510356A1 (en) 1992-10-28
AU671045B2 (en) 1996-08-08
US5595732A (en) 1997-01-21
SI9210294A (en) 1995-10-31
US5539063A (en) 1996-07-23
CN1108814C (zh) 2003-05-21
HU9200955D0 (en) 1992-05-28
MW1892A1 (en) 1994-01-12
CN1065465A (zh) 1992-10-21

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