EE200300121A - CB1 retseptori antagonisti ja sibutramiini kombinatsioon, neid sisaldav farmatseutiline kompositsioon ja kasutamine lihavuse raviks - Google Patents

CB1 retseptori antagonisti ja sibutramiini kombinatsioon, neid sisaldav farmatseutiline kompositsioon ja kasutamine lihavuse raviks

Info

Publication number
EE200300121A
EE200300121A EEP200300121A EEP200300121A EE200300121A EE 200300121 A EE200300121 A EE 200300121A EE P200300121 A EEP200300121 A EE P200300121A EE P200300121 A EEP200300121 A EE P200300121A EE 200300121 A EE200300121 A EE 200300121A
Authority
EE
Estonia
Prior art keywords
receptor antagonist
obesity
sibutramine
treatment
combination
Prior art date
Application number
EEP200300121A
Other languages
English (en)
Estonian (et)
Inventor
Piot-Grosjean Odile
Picaut Philippe
Petitet Fran�ois
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8854974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE200300121(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of EE200300121A publication Critical patent/EE200300121A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
EEP200300121A 2000-10-04 2001-10-01 CB1 retseptori antagonisti ja sibutramiini kombinatsioon, neid sisaldav farmatseutiline kompositsioon ja kasutamine lihavuse raviks EE200300121A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0012646A FR2814678B1 (fr) 2000-10-04 2000-10-04 Association d'un antagoniste du recepteur cb1 et de sibutramine, les compositions pharmaceutiques les contenant et leur utilisation pour la traitement de l'obesite
PCT/FR2001/003022 WO2002028346A2 (fr) 2000-10-04 2001-10-01 Association d'un antagoniste du recepteur cb1 et de sibutramine, pour le traitement de l'obesite

Publications (1)

Publication Number Publication Date
EE200300121A true EE200300121A (et) 2005-04-15

Family

ID=8854974

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300121A EE200300121A (et) 2000-10-04 2001-10-01 CB1 retseptori antagonisti ja sibutramiini kombinatsioon, neid sisaldav farmatseutiline kompositsioon ja kasutamine lihavuse raviks

Country Status (29)

Country Link
EP (1) EP1328269B2 (zh)
JP (1) JP4221221B2 (zh)
KR (1) KR20030036885A (zh)
CN (1) CN100409845C (zh)
AT (1) ATE267595T1 (zh)
AU (2) AU9393601A (zh)
BG (1) BG107739A (zh)
BR (1) BR0114410A (zh)
CA (1) CA2424934A1 (zh)
DE (1) DE60103556T3 (zh)
DK (1) DK1328269T5 (zh)
EA (1) EA005924B1 (zh)
EE (1) EE200300121A (zh)
ES (1) ES2217191T5 (zh)
FR (1) FR2814678B1 (zh)
HR (1) HRP20030249A2 (zh)
HU (1) HUP0302044A3 (zh)
IL (1) IL155236A0 (zh)
MX (1) MXPA03002845A (zh)
NO (1) NO20031521L (zh)
NZ (1) NZ524904A (zh)
PL (1) PL362833A1 (zh)
PT (1) PT1328269E (zh)
SI (1) SI1328269T2 (zh)
SK (1) SK4032003A3 (zh)
TR (1) TR200401264T4 (zh)
WO (1) WO2002028346A2 (zh)
YU (1) YU26103A (zh)
ZA (1) ZA200303015B (zh)

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WO2004013120A1 (en) 2002-07-29 2004-02-12 F. Hoffmann-La Roche Ag Novel benzodioxoles
DE60330392D1 (de) 2003-01-02 2010-01-14 Hoffmann La Roche Cb 1 rezeptor inversagonisten
DE60322114D1 (de) 2003-01-02 2008-08-21 Hoffmann La Roche Pyrrolyl-thiazole und ihre verwendung als inverse agonisten des cb 1 rezeptors
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US20040224962A1 (en) * 2003-05-09 2004-11-11 Pfizer Inc Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss
US7485732B2 (en) 2003-06-11 2009-02-03 Merck & Co., Inc. Substituted 3-alkyl and 3-alkenyl azetidine derivatives
CN100368407C (zh) 2003-06-20 2008-02-13 霍夫曼-拉罗奇有限公司 作为cb1受体反激动剂的2-酰氨基苯并噻唑
EP1498123A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Emulsifying systems containing azetidine derivatives
EP1498122A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Semi-solid systems containing azetidine derivatives
CA2537535A1 (en) * 2003-09-02 2005-03-10 Solvay Pharmaceuticals Gmbh Novel medical use of selective cb1-receptor antagonists
FR2861303A1 (fr) * 2003-10-24 2005-04-29 Sanofi Synthelabo Utilisation d'un derive de pyrazole pour la preparation de medicaments utiles dans la prevention et le traitement du syndrome metabolique
WO2005049615A1 (en) * 2003-11-21 2005-06-02 Pfizer Products Inc. Pyrazolo`1,5-a!`1,3,5! triazin -4-one derivatives as cb1 receptor antagonists
KR100773650B1 (ko) 2003-12-08 2007-11-05 에프. 호프만-라 로슈 아게 신규한 싸이아졸 유도체
JP4436369B2 (ja) 2004-01-28 2010-03-24 エフ．ホフマン−ラ ロシュ アーゲー スピロ−ベンゾジオキソール類およびそれらのｃｂ１アンタゴニストとしての使用
ES2324720T3 (es) 2004-05-10 2009-08-13 F. Hoffmann-La Roche Ag Pirrol o imidazol amidas para tratar la obesidad.
US20060025448A1 (en) 2004-07-22 2006-02-02 Cadila Healthcare Limited Hair growth stimulators
EP1807070A1 (en) * 2004-09-29 2007-07-18 Schering Corporation Combinations of substituted azetidinones and cb1 antagonists
FR2876689B1 (fr) * 2004-10-14 2008-02-22 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de derives de n-(1-benzhydryl-azetidin-3-yl)-n-phenyl-methylsulfonamide
RU2007119315A (ru) 2004-10-25 2008-11-27 Зольвай Фармасьютиклз Гмбх (De) Фармацевтические композиции, содержащие антагонисты каннабиноидного рецептора св1 и открыватели калиевых каналов, предназначенные для лечения сахарного диабета типа i, ожирения и связанных с ними состояний
RU2394027C2 (ru) 2004-10-27 2010-07-10 Ф. Хоффманн-Ля Рош Аг Новые индольные или бензимидазольные производные
EP1812418B1 (en) 2004-11-09 2010-10-27 F. Hoffmann-La Roche AG Dibenzosuberone derivatives
ATE435207T1 (de) 2005-04-06 2009-07-15 Hoffmann La Roche Pyridin-3-carbonsäureamidderivate als cb1-inverse agonisten
US7906652B2 (en) 2005-11-28 2011-03-15 Merck Sharp & Dohme Corp. Heterocycle-substituted 3-alkyl azetidine derivatives
WO2007102999A2 (en) * 2006-02-21 2007-09-13 Ampla Pharmaceuticals Inc. Cb1 antagonists and inverse agonists
WO2007110449A1 (en) * 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
US8791264B2 (en) 2006-04-13 2014-07-29 Purdue Pharma L.P. Benzenesulfonamide compounds and their use as blockers of calcium channels
US7629346B2 (en) 2006-06-19 2009-12-08 Hoffmann-La Roche Inc. Pyrazinecarboxamide derivatives as CB1 antagonists
WO2008038143A2 (en) * 2006-06-22 2008-04-03 Medichem, S.A. Novel solid forms of rimonabant and synthetic processes for their preparation
EP2057144A4 (en) * 2006-09-01 2010-06-02 Hetero Drugs Ltd NEW POLYMORPHIC FROM RIMONABANT
US7781593B2 (en) 2006-09-14 2010-08-24 Hoffmann-La Roche Inc. 5-phenyl-nicotinamide derivatives
BRPI0718515A2 (pt) * 2006-09-25 2013-11-19 Boehringer Ingelheim Int Compostos que modulam o receptor cb2
DE102007002260A1 (de) 2007-01-16 2008-07-31 Sanofi-Aventis Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms
EP1953144A1 (en) * 2007-01-30 2008-08-06 Sandoz AG Novel polymorphic forms of N-piperidino-5-(4-chlorophenyl)-1-(2, 4-dichlorphenyl)-4-methyl-3-pyrazolecarboxamide
WO2008124118A1 (en) 2007-04-09 2008-10-16 Purdue Pharma L.P. Benzenesulfonyl compounds and the use therof
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
SI2234966T1 (sl) * 2007-12-18 2014-01-31 Sanofi Derivati azetidinov, njihova priprava in njihova terapevtska uporaba
WO2010079241A1 (es) 2009-01-12 2010-07-15 Fundacion Hospital Nacional De Paraplejicos Para La Investigacion Y La Integracion Uso de antagonistas y/o agonistas inversos de los receptores cb1 para la preparación de medicamentos que incrementen la excitabilidad de las motoneuronas
BRPI0902481B8 (pt) 2009-07-31 2021-05-25 Soc Beneficente De Senhoras Hospital Sirio Libanes composição farmacêutica compreendendo hemopressina e seu uso.
US8410107B2 (en) 2010-10-15 2013-04-02 Hoffmann-La Roche Inc. N-pyridin-3-yl or N-pyrazin-2-yl carboxamides
US8669254B2 (en) 2010-12-15 2014-03-11 Hoffman-La Roche Inc. Pyridine, pyridazine, pyrimidine or pyrazine carboxamides as HDL-cholesterol raising agents

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Also Published As

Publication number Publication date
JP2004512279A (ja) 2004-04-22
HUP0302044A2 (hu) 2003-11-28
FR2814678B1 (fr) 2002-12-20
DE60103556T2 (de) 2005-06-30
CN1473040A (zh) 2004-02-04
BG107739A (bg) 2004-01-30
EP1328269B2 (fr) 2008-07-30
YU26103A (sh) 2006-08-17
DK1328269T3 (da) 2004-09-20
HUP0302044A3 (en) 2005-05-30
JP4221221B2 (ja) 2009-02-12
SK4032003A3 (en) 2003-09-11
HRP20030249A2 (en) 2005-02-28
MXPA03002845A (es) 2004-09-10
ZA200303015B (en) 2004-02-26
SI1328269T2 (sl) 2008-12-31
BR0114410A (pt) 2004-02-17
ES2217191T3 (es) 2004-11-01
ATE267595T1 (de) 2004-06-15
WO2002028346A3 (fr) 2002-08-29
CN100409845C (zh) 2008-08-13
FR2814678A1 (fr) 2002-04-05
DK1328269T4 (da) 2008-11-24
EA200300441A1 (ru) 2003-08-28
EP1328269B1 (fr) 2004-05-26
NZ524904A (en) 2004-11-26
DE60103556D1 (de) 2004-07-01
ES2217191T5 (es) 2009-02-16
WO2002028346A2 (fr) 2002-04-11
AU9393601A (en) 2002-04-15
EP1328269A2 (fr) 2003-07-23
KR20030036885A (ko) 2003-05-09
IL155236A0 (en) 2003-11-23
PL362833A1 (en) 2004-11-02
EA005924B1 (ru) 2005-08-25
NO20031521D0 (no) 2003-04-03
SI1328269T1 (en) 2004-10-31
AU2001293936B2 (en) 2007-01-25
TR200401264T4 (tr) 2004-07-21
DE60103556T3 (de) 2009-04-09
NO20031521L (no) 2003-04-24
PT1328269E (pt) 2004-08-31
DK1328269T5 (da) 2009-03-16
CA2424934A1 (fr) 2002-04-11

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