EE200200367A - Kondenseeritud asepiinid kui vasopressiini agonistid - Google Patents

Kondenseeritud asepiinid kui vasopressiini agonistid

Info

Publication number
EE200200367A
EE200200367A EEP200200367A EEP200200367A EE200200367A EE 200200367 A EE200200367 A EE 200200367A EE P200200367 A EEP200200367 A EE P200200367A EE P200200367 A EEP200200367 A EE P200200367A EE 200200367 A EE200200367 A EE 200200367A
Authority
EE
Estonia
Prior art keywords
vasopressin agonists
azepines
condensed
condensed azepines
vasopressin
Prior art date
Application number
EEP200200367A
Other languages
English (en)
Estonian (et)
Inventor
Mary Ashworth Doreen
Robert William Pitt Gary
Hudson Peter
Martyn Yea Christopher
Jeremy Franklin Richard
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of EE200200367A publication Critical patent/EE200200367A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
EEP200200367A 2000-01-05 2001-01-04 Kondenseeritud asepiinid kui vasopressiini agonistid EE200200367A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0000079.4A GB0000079D0 (en) 2000-01-05 2000-01-05 Novel antidiuretic agents
PCT/GB2001/000023 WO2001049682A1 (en) 2000-01-05 2001-01-04 Condensed azepines as vasopressin agonists

Publications (1)

Publication Number Publication Date
EE200200367A true EE200200367A (et) 2003-12-15

Family

ID=9883168

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200367A EE200200367A (et) 2000-01-05 2001-01-04 Kondenseeritud asepiinid kui vasopressiini agonistid

Country Status (34)

Country Link
US (3) US7074781B2 (bg)
EP (1) EP1248784B1 (bg)
JP (2) JP3869723B2 (bg)
KR (1) KR100605466B1 (bg)
CN (1) CN1183129C (bg)
AR (1) AR035327A1 (bg)
AT (1) ATE366730T1 (bg)
AU (1) AU777538B2 (bg)
BR (1) BR0107414B1 (bg)
CA (1) CA2396277C (bg)
CY (1) CY1108034T1 (bg)
CZ (1) CZ303444B6 (bg)
DE (1) DE60129298T2 (bg)
DK (1) DK1248784T3 (bg)
EE (1) EE200200367A (bg)
ES (1) ES2288923T3 (bg)
GB (1) GB0000079D0 (bg)
HK (1) HK1046910B (bg)
HR (1) HRP20020481B1 (bg)
HU (1) HU229937B1 (bg)
IL (1) IL149528A0 (bg)
MX (1) MXPA02006546A (bg)
MY (1) MY140467A (bg)
NO (1) NO322571B1 (bg)
NZ (1) NZ518803A (bg)
PL (1) PL211341B1 (bg)
PT (1) PT1248784E (bg)
RU (1) RU2259367C2 (bg)
SI (1) SI1248784T1 (bg)
SK (1) SK287005B6 (bg)
UA (1) UA73152C2 (bg)
UY (1) UY26521A1 (bg)
WO (1) WO2001049682A1 (bg)
ZA (1) ZA200205180B (bg)

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US7138393B2 (en) 1998-07-24 2006-11-21 Wyeth Biologically active vasopressin agonist metabolites
GB0000079D0 (en) * 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
EP1268418B1 (en) * 2000-03-27 2006-06-14 Applied Research Systems ARS Holding N.V. Pharmaceutically active pyrrolidine derivatives as bax inhibitors
SI1268419T1 (sl) * 2000-03-27 2006-10-31 Applied Research Systems Pirolidinski derivati, uporabni kot bax inhibitorji
GB0015601D0 (en) * 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents
GB0115515D0 (en) * 2001-06-25 2001-08-15 Ferring Bv Oxytocin agonisys
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
PT1619185E (pt) * 2003-04-28 2011-08-25 Astellas Pharma Inc Derivado de 4,4-difluoro-1,2,3,4-tetra-hidro-5h-1-benzazepina ou um seu sal
EP1530967B1 (en) * 2003-11-13 2006-05-03 Ferring B.V. Blister pack and solid dosage form comprising desmopressin
JP4943858B2 (ja) * 2004-11-17 2012-05-30 キッセイ薬品工業株式会社 芳香族アミド誘導体、それを含有する医薬組成物およびそれらの医薬用途
CA2602351A1 (en) * 2005-03-25 2006-10-05 Kissei Pharmaceutical Co., Ltd. Urea derivative, medicinal composition containing the same, and medicinal use of these
WO2007052517A1 (ja) * 2005-10-31 2007-05-10 Sumitomo Chemical Company, Limited ヒドロキシ-2-ピロリジンカルボキシアミド化合物の製法
TW200820976A (en) * 2006-09-25 2008-05-16 Kissei Pharmaceutical 1,4-benzodiazepine derivative, pharmaceutical composition comprising the same, and use of the same for medical purposes
BRPI0811204A8 (pt) * 2007-05-10 2015-09-22 Bristol Myers Squibb Co Tetra-hidroibenzo-1,4-diazepinas substituídas por arila e heteroarila e uso das mesmas para bloquear a recaptação de norepinefrina, dopamina e serotonina
BRPI0814986A2 (pt) 2007-08-06 2015-02-03 Serenity Pharmaceuticals Corp Métodos e dispositivos para a distribuição de fármaco desmopresina.
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
LT3225250T (lt) * 2008-05-21 2019-11-11 Ferring Bv Burnoje disperguojamas desmopresinas, skirtas nikturijos nepertraukiamo miego pirminio periodo pailginimui
GB201005623D0 (en) 2010-04-01 2010-05-19 Vantia Ltd New polymorph
GB201105537D0 (en) 2011-03-31 2011-05-18 Vantia Ltd New process
WO2020154581A1 (en) 2019-01-24 2020-07-30 Assia Chemical Industries Ltd Solid state forms of fedovapagon-salicyclic acid co-crystal

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CA1265798A (en) 1984-12-10 1990-02-13 Motoo Mutsukado 3(2h)pyridazinone, process for its preparation and anti-allergic agent containing it
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CA2066104C (en) 1991-04-19 2003-05-27 Hidenori Ogawa Benzazepine derivatives as vasopressin antagonists
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GB0000079D0 (en) 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
GB0015601D0 (en) 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents
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GB0120051D0 (en) 2001-08-16 2001-10-10 Ferring Bv Oxytocin agonists
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US7341963B2 (en) * 2005-05-17 2008-03-11 Milliken & Company Non-woven material with barrier skin

Also Published As

Publication number Publication date
JP3869723B2 (ja) 2007-01-17
ES2288923T3 (es) 2008-02-01
WO2001049682A1 (en) 2001-07-12
HU229937B1 (hu) 2015-01-28
PL211341B1 (pl) 2012-05-31
SK9112002A3 (en) 2003-01-09
SI1248784T1 (sl) 2007-12-31
CZ20022305A3 (cs) 2002-10-16
ATE366730T1 (de) 2007-08-15
BR0107414A (pt) 2002-10-08
MY140467A (en) 2009-12-31
US7560454B2 (en) 2009-07-14
PT1248784E (pt) 2007-10-02
IL149528A0 (en) 2002-11-10
DE60129298T2 (de) 2008-01-03
GB0000079D0 (en) 2000-02-23
NZ518803A (en) 2003-03-28
AR035327A1 (es) 2004-05-12
KR20020063191A (ko) 2002-08-01
HUP0203917A2 (hu) 2003-03-28
JP3813629B2 (ja) 2006-08-23
CY1108034T1 (el) 2013-09-04
KR100605466B1 (ko) 2006-07-28
JP2003519228A (ja) 2003-06-17
CZ303444B6 (cs) 2012-09-19
EP1248784A1 (en) 2002-10-16
AU777538B2 (en) 2004-10-21
HK1046910B (zh) 2007-08-31
US20080261951A1 (en) 2008-10-23
HRP20020481B1 (en) 2009-03-31
US7074781B2 (en) 2006-07-11
AU2384601A (en) 2001-07-16
MXPA02006546A (es) 2002-12-09
US20060154916A1 (en) 2006-07-13
SK287005B6 (sk) 2009-09-07
UA73152C2 (en) 2005-06-15
EP1248784B1 (en) 2007-07-11
JP2006137767A (ja) 2006-06-01
RU2259367C2 (ru) 2005-08-27
NO20023137L (no) 2002-06-27
NO322571B1 (no) 2006-10-30
BR0107414B1 (pt) 2014-09-16
HK1046910A1 (en) 2003-01-30
DE60129298D1 (de) 2007-08-23
RU2002120798A (ru) 2004-01-10
ZA200205180B (en) 2004-02-05
HUP0203917A3 (en) 2004-07-28
DK1248784T3 (da) 2007-10-29
NO20023137D0 (no) 2002-06-27
CA2396277A1 (en) 2001-07-12
CN1392875A (zh) 2003-01-22
US20030087892A1 (en) 2003-05-08
PL355808A1 (en) 2004-05-17
CN1183129C (zh) 2005-01-05
CA2396277C (en) 2012-03-20
HRP20020481A2 (en) 2004-08-31
UY26521A1 (es) 2001-03-16

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