ATE360617T1 - Benzoheterocyclische verbindungen verwendbar als vasopressin- oder oxytocin-modulatoren - Google Patents
Benzoheterocyclische verbindungen verwendbar als vasopressin- oder oxytocin-modulatorenInfo
- Publication number
- ATE360617T1 ATE360617T1 AT02007987T AT02007987T ATE360617T1 AT E360617 T1 ATE360617 T1 AT E360617T1 AT 02007987 T AT02007987 T AT 02007987T AT 02007987 T AT02007987 T AT 02007987T AT E360617 T1 ATE360617 T1 AT E360617T1
- Authority
- AT
- Austria
- Prior art keywords
- vasopressin
- benzohetrocyclic
- oxytocin
- compounds usable
- activity
- Prior art date
Links
- 229960003726 vasopressin Drugs 0.000 title abstract 3
- 101800000989 Oxytocin Proteins 0.000 title abstract 2
- XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 title abstract 2
- 102100031951 Oxytocin-neurophysin 1 Human genes 0.000 title abstract 2
- GXBMIBRIOWHPDT-UHFFFAOYSA-N Vasopressin Natural products N1C(=O)C(CC=2C=C(O)C=CC=2)NC(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CC1=CC=CC=C1 GXBMIBRIOWHPDT-UHFFFAOYSA-N 0.000 title abstract 2
- 108010004977 Vasopressins Proteins 0.000 title abstract 2
- 102000002852 Vasopressins Human genes 0.000 title abstract 2
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 title abstract 2
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 title abstract 2
- 229960001723 oxytocin Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 229940083335 Vasopressin agonist Drugs 0.000 abstract 1
- 229940116211 Vasopressin antagonist Drugs 0.000 abstract 1
- 230000001270 agonistic effect Effects 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003336 oxytocin antagonist Substances 0.000 abstract 1
- 229940121361 oxytocin antagonists Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003038 vasopressin antagonist Substances 0.000 abstract 1
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13235594 | 1994-06-15 | ||
| JP7072795 | 1995-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE360617T1 true ATE360617T1 (de) | 2007-05-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95921112T ATE239710T1 (de) | 1994-06-15 | 1995-06-07 | Benzoheterocyclische derivate verwendbar als vasopressin- oder oxytocin-modulatoren |
| AT02007987T ATE360617T1 (de) | 1994-06-15 | 1995-06-07 | Benzoheterocyclische verbindungen verwendbar als vasopressin- oder oxytocin-modulatoren |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95921112T ATE239710T1 (de) | 1994-06-15 | 1995-06-07 | Benzoheterocyclische derivate verwendbar als vasopressin- oder oxytocin-modulatoren |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US6096735A (de) |
| EP (2) | EP1221440B1 (de) |
| JP (1) | JP2000351768A (de) |
| KR (1) | KR100433375B1 (de) |
| CN (2) | CN100384825C (de) |
| AT (2) | ATE239710T1 (de) |
| CA (1) | CA2192928C (de) |
| DE (2) | DE69535486T2 (de) |
| DK (2) | DK0765314T3 (de) |
| ES (2) | ES2284741T3 (de) |
| MX (1) | MX9606510A (de) |
| PT (2) | PT1221440E (de) |
| TW (1) | TW467899B (de) |
| WO (1) | WO1995034540A1 (de) |
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| FR2781371B1 (fr) * | 1998-07-21 | 2001-04-27 | Oreal | Composition cosmetique aqueuse transparente a une seule phase |
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| US7138393B2 (en) | 1998-07-24 | 2006-11-21 | Wyeth | Biologically active vasopressin agonist metabolites |
| US6620807B1 (en) | 1999-02-04 | 2003-09-16 | Wyeth | Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists |
| US6235900B1 (en) | 1999-02-04 | 2001-05-22 | American Home Products Corporation | Tricyclic pyridine N-oxides vasopressin agonists |
| US6344451B1 (en) | 1999-02-04 | 2002-02-05 | American Home Products | Pyrrolobenzodiazepine carboxyamide vasopressin agonists |
| DE19962923A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Benzoylcyclohexandione |
| GB0000079D0 (en) | 2000-01-05 | 2000-02-23 | Ferring Bv | Novel antidiuretic agents |
| GB0015601D0 (en) | 2000-06-26 | 2000-08-16 | Ferring Bv | Novel antidiuretic agents |
| EP2140862A3 (de) * | 2001-01-31 | 2010-02-17 | H.Lundbeck A/S | Verwendung von GAL3-Rezeptor-Antagonisten zur Behandlung von Depression und/oder Angstzuständen und für solche Verfahren nützliche Verbindungen |
| JP2004530668A (ja) | 2001-04-12 | 2004-10-07 | ワイス | バソプレッシンアゴニストとしてのn−ビフェニルカルボニル−およびn−フェニルピリジルカルボニル置換二および三環アゼピンおよびジアゼピン |
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| EP2131655B1 (de) * | 2007-03-02 | 2014-05-07 | The University of Tennessee Research Foundation | Triaryl-/heteroaromatische cannabinoide und ihre verwendung |
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| CN114212784A (zh) * | 2021-11-26 | 2022-03-22 | 唐山金湾特碳石墨有限公司 | 一种用于摩擦材料的石墨制备方法 |
| CN116789674B (zh) * | 2022-08-24 | 2024-05-24 | 杭州高光制药有限公司 | Nlrp3炎性小体抑制剂 |
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| US3516987A (en) | 1966-04-25 | 1970-06-23 | American Home Prod | 1-methylsulfonyl-7-methoxy-2,3,4,5-tetrahydro-1h-1-benzazepine |
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| US3458498A (en) | 1966-04-25 | 1969-07-29 | American Home Prod | Certain 1-acyl derivatives of 7-alkoxy-2,3,4,5-tetrahydro-1h-1-benzazepine |
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| GB9307527D0 (en) * | 1993-04-13 | 1993-06-02 | Fujisawa Pharmaceutical Co | New venzamide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
-
1995
- 1995-06-07 DE DE69535486T patent/DE69535486T2/de not_active Expired - Lifetime
- 1995-06-07 PT PT02007987T patent/PT1221440E/pt unknown
- 1995-06-07 KR KR1019960706863A patent/KR100433375B1/ko not_active Expired - Lifetime
- 1995-06-07 ES ES02007987T patent/ES2284741T3/es not_active Expired - Lifetime
- 1995-06-07 CA CA2192928A patent/CA2192928C/en not_active Expired - Lifetime
- 1995-06-07 DK DK95921112T patent/DK0765314T3/da active
- 1995-06-07 WO PCT/JP1995/001124 patent/WO1995034540A1/en not_active Ceased
- 1995-06-07 PT PT95921112T patent/PT765314E/pt unknown
- 1995-06-07 DE DE69530690T patent/DE69530690T2/de not_active Expired - Lifetime
- 1995-06-07 EP EP02007987A patent/EP1221440B1/de not_active Expired - Lifetime
- 1995-06-07 CN CNB001317873A patent/CN100384825C/zh not_active Expired - Lifetime
- 1995-06-07 US US08/737,432 patent/US6096735A/en not_active Expired - Lifetime
- 1995-06-07 AT AT95921112T patent/ATE239710T1/de active
- 1995-06-07 MX MX9606510A patent/MX9606510A/es unknown
- 1995-06-07 AT AT02007987T patent/ATE360617T1/de active
- 1995-06-07 CN CN95193642A patent/CN1104418C/zh not_active Expired - Lifetime
- 1995-06-07 ES ES95921112T patent/ES2199251T3/es not_active Expired - Lifetime
- 1995-06-07 EP EP95921112A patent/EP0765314B1/de not_active Expired - Lifetime
- 1995-06-07 DK DK02007987T patent/DK1221440T3/da active
- 1995-06-08 TW TW084105805A patent/TW467899B/zh not_active IP Right Cessation
-
1999
- 1999-11-01 US US09/431,635 patent/US6335327B1/en not_active Expired - Lifetime
-
2000
- 2000-05-26 JP JP2000155830A patent/JP2000351768A/ja active Pending
-
2001
- 2001-06-06 US US09/874,452 patent/US6642223B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2629395A (en) | 1996-01-05 |
| PT1221440E (pt) | 2007-07-20 |
| ES2199251T3 (es) | 2004-02-16 |
| PT765314E (pt) | 2003-09-30 |
| DK1221440T3 (da) | 2007-09-17 |
| US6642223B2 (en) | 2003-11-04 |
| TW467899B (en) | 2001-12-11 |
| WO1995034540A1 (en) | 1995-12-21 |
| EP0765314B1 (de) | 2003-05-07 |
| DE69530690D1 (de) | 2003-06-12 |
| EP1221440B1 (de) | 2007-04-25 |
| US6335327B1 (en) | 2002-01-01 |
| DE69535486D1 (de) | 2007-06-06 |
| CN100384825C (zh) | 2008-04-30 |
| KR100433375B1 (ko) | 2005-09-23 |
| CA2192928C (en) | 2010-10-26 |
| ATE239710T1 (de) | 2003-05-15 |
| CA2192928A1 (en) | 1995-12-21 |
| CN1150799A (zh) | 1997-05-28 |
| AU690283B2 (en) | 1998-04-23 |
| JP2000351768A (ja) | 2000-12-19 |
| EP1221440A1 (de) | 2002-07-10 |
| CN1313280A (zh) | 2001-09-19 |
| DK0765314T3 (da) | 2003-08-25 |
| CN1104418C (zh) | 2003-04-02 |
| DE69530690T2 (de) | 2004-03-18 |
| ES2284741T3 (es) | 2007-11-16 |
| KR970703317A (ko) | 1997-07-03 |
| DE69535486T2 (de) | 2008-04-10 |
| EP0765314A1 (de) | 1997-04-02 |
| US6096735A (en) | 2000-08-01 |
| MX9606510A (es) | 1997-03-29 |
| US20020049194A1 (en) | 2002-04-25 |
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