ATE360617T1 - Benzoheterocyclische verbindungen verwendbar als vasopressin- oder oxytocin-modulatoren - Google Patents
Benzoheterocyclische verbindungen verwendbar als vasopressin- oder oxytocin-modulatorenInfo
- Publication number
- ATE360617T1 ATE360617T1 AT02007987T AT02007987T ATE360617T1 AT E360617 T1 ATE360617 T1 AT E360617T1 AT 02007987 T AT02007987 T AT 02007987T AT 02007987 T AT02007987 T AT 02007987T AT E360617 T1 ATE360617 T1 AT E360617T1
- Authority
- AT
- Austria
- Prior art keywords
- vasopressin
- benzohetrocyclic
- oxytocin
- compounds usable
- activity
- Prior art date
Links
- 229960003726 vasopressin Drugs 0.000 title abstract 3
- 101800000989 Oxytocin Proteins 0.000 title abstract 2
- XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 title abstract 2
- 102100031951 Oxytocin-neurophysin 1 Human genes 0.000 title abstract 2
- GXBMIBRIOWHPDT-UHFFFAOYSA-N Vasopressin Natural products N1C(=O)C(CC=2C=C(O)C=CC=2)NC(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CC1=CC=CC=C1 GXBMIBRIOWHPDT-UHFFFAOYSA-N 0.000 title abstract 2
- 108010004977 Vasopressins Proteins 0.000 title abstract 2
- 102000002852 Vasopressins Human genes 0.000 title abstract 2
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 title abstract 2
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 title abstract 2
- 229960001723 oxytocin Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 229940083335 Vasopressin agonist Drugs 0.000 abstract 1
- 229940116211 Vasopressin antagonist Drugs 0.000 abstract 1
- 230000001270 agonistic effect Effects 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003336 oxytocin antagonist Substances 0.000 abstract 1
- 229940121361 oxytocin antagonists Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003038 vasopressin antagonist Substances 0.000 abstract 1
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13235594 | 1994-06-15 | ||
| JP7072795 | 1995-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE360617T1 true ATE360617T1 (de) | 2007-05-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02007987T ATE360617T1 (de) | 1994-06-15 | 1995-06-07 | Benzoheterocyclische verbindungen verwendbar als vasopressin- oder oxytocin-modulatoren |
| AT95921112T ATE239710T1 (de) | 1994-06-15 | 1995-06-07 | Benzoheterocyclische derivate verwendbar als vasopressin- oder oxytocin-modulatoren |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95921112T ATE239710T1 (de) | 1994-06-15 | 1995-06-07 | Benzoheterocyclische derivate verwendbar als vasopressin- oder oxytocin-modulatoren |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US6096735A (de) |
| EP (2) | EP1221440B1 (de) |
| JP (1) | JP2000351768A (de) |
| KR (1) | KR100433375B1 (de) |
| CN (2) | CN100384825C (de) |
| AT (2) | ATE360617T1 (de) |
| CA (1) | CA2192928C (de) |
| DE (2) | DE69535486T2 (de) |
| DK (2) | DK0765314T3 (de) |
| ES (2) | ES2199251T3 (de) |
| MX (1) | MX9606510A (de) |
| PT (2) | PT1221440E (de) |
| TW (1) | TW467899B (de) |
| WO (1) | WO1995034540A1 (de) |
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| FR2781371B1 (fr) * | 1998-07-21 | 2001-04-27 | Oreal | Composition cosmetique aqueuse transparente a une seule phase |
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| US7138393B2 (en) | 1998-07-24 | 2006-11-21 | Wyeth | Biologically active vasopressin agonist metabolites |
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| US6235900B1 (en) | 1999-02-04 | 2001-05-22 | American Home Products Corporation | Tricyclic pyridine N-oxides vasopressin agonists |
| US6344451B1 (en) | 1999-02-04 | 2002-02-05 | American Home Products | Pyrrolobenzodiazepine carboxyamide vasopressin agonists |
| DE19962923A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Benzoylcyclohexandione |
| GB0000079D0 (en) | 2000-01-05 | 2000-02-23 | Ferring Bv | Novel antidiuretic agents |
| GB0015601D0 (en) * | 2000-06-26 | 2000-08-16 | Ferring Bv | Novel antidiuretic agents |
| CN101406469B (zh) * | 2001-01-31 | 2012-06-13 | H·隆德贝克有限公司 | Gal3受体拮抗剂在治疗抑郁和/或焦虑中的应用及在这种方法中有用的化合物 |
| WO2002083145A1 (en) | 2001-04-12 | 2002-10-24 | Wyeth | N-biphenylcarbonyl- and n-phenylpyridylcarbonyl substituted bi- and tricyclic azepines and diazepines as vasopressing agonists |
| EP1381608B1 (de) * | 2001-04-12 | 2007-10-10 | Wyeth | Cyclohexylphenyl vasopressin agonisten |
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| CN114212784A (zh) * | 2021-11-26 | 2022-03-22 | 唐山金湾特碳石墨有限公司 | 一种用于摩擦材料的石墨制备方法 |
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| US3458498A (en) | 1966-04-25 | 1969-07-29 | American Home Prod | Certain 1-acyl derivatives of 7-alkoxy-2,3,4,5-tetrahydro-1h-1-benzazepine |
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| US3542760A (en) | 1966-04-25 | 1970-11-24 | American Home Prod | 7-alkoxy-2,3,4,5-tetrahydro-1h-1-benzazepine and derivatives thereof |
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| GB9307527D0 (en) * | 1993-04-13 | 1993-06-02 | Fujisawa Pharmaceutical Co | New venzamide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
-
1995
- 1995-06-07 AT AT02007987T patent/ATE360617T1/de active
- 1995-06-07 DK DK95921112T patent/DK0765314T3/da active
- 1995-06-07 DK DK02007987T patent/DK1221440T3/da active
- 1995-06-07 WO PCT/JP1995/001124 patent/WO1995034540A1/en not_active Ceased
- 1995-06-07 EP EP02007987A patent/EP1221440B1/de not_active Expired - Lifetime
- 1995-06-07 PT PT02007987T patent/PT1221440E/pt unknown
- 1995-06-07 US US08/737,432 patent/US6096735A/en not_active Expired - Lifetime
- 1995-06-07 DE DE69535486T patent/DE69535486T2/de not_active Expired - Lifetime
- 1995-06-07 CN CNB001317873A patent/CN100384825C/zh not_active Expired - Lifetime
- 1995-06-07 KR KR1019960706863A patent/KR100433375B1/ko not_active Expired - Lifetime
- 1995-06-07 AT AT95921112T patent/ATE239710T1/de active
- 1995-06-07 ES ES95921112T patent/ES2199251T3/es not_active Expired - Lifetime
- 1995-06-07 MX MX9606510A patent/MX9606510A/es unknown
- 1995-06-07 CA CA2192928A patent/CA2192928C/en not_active Expired - Lifetime
- 1995-06-07 EP EP95921112A patent/EP0765314B1/de not_active Expired - Lifetime
- 1995-06-07 ES ES02007987T patent/ES2284741T3/es not_active Expired - Lifetime
- 1995-06-07 CN CN95193642A patent/CN1104418C/zh not_active Expired - Lifetime
- 1995-06-07 DE DE69530690T patent/DE69530690T2/de not_active Expired - Lifetime
- 1995-06-07 PT PT95921112T patent/PT765314E/pt unknown
- 1995-06-08 TW TW084105805A patent/TW467899B/zh not_active IP Right Cessation
-
1999
- 1999-11-01 US US09/431,635 patent/US6335327B1/en not_active Expired - Lifetime
-
2000
- 2000-05-26 JP JP2000155830A patent/JP2000351768A/ja active Pending
-
2001
- 2001-06-06 US US09/874,452 patent/US6642223B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69530690D1 (de) | 2003-06-12 |
| AU690283B2 (en) | 1998-04-23 |
| US20020049194A1 (en) | 2002-04-25 |
| MX9606510A (es) | 1997-03-29 |
| KR100433375B1 (ko) | 2005-09-23 |
| CN1104418C (zh) | 2003-04-02 |
| AU2629395A (en) | 1996-01-05 |
| KR970703317A (ko) | 1997-07-03 |
| DK1221440T3 (da) | 2007-09-17 |
| DE69535486T2 (de) | 2008-04-10 |
| US6335327B1 (en) | 2002-01-01 |
| JP2000351768A (ja) | 2000-12-19 |
| DE69530690T2 (de) | 2004-03-18 |
| TW467899B (en) | 2001-12-11 |
| ATE239710T1 (de) | 2003-05-15 |
| CA2192928A1 (en) | 1995-12-21 |
| EP0765314A1 (de) | 1997-04-02 |
| WO1995034540A1 (en) | 1995-12-21 |
| EP1221440B1 (de) | 2007-04-25 |
| ES2284741T3 (es) | 2007-11-16 |
| CA2192928C (en) | 2010-10-26 |
| EP1221440A1 (de) | 2002-07-10 |
| CN1150799A (zh) | 1997-05-28 |
| US6642223B2 (en) | 2003-11-04 |
| PT765314E (pt) | 2003-09-30 |
| EP0765314B1 (de) | 2003-05-07 |
| PT1221440E (pt) | 2007-07-20 |
| DE69535486D1 (de) | 2007-06-06 |
| CN100384825C (zh) | 2008-04-30 |
| CN1313280A (zh) | 2001-09-19 |
| DK0765314T3 (da) | 2003-08-25 |
| US6096735A (en) | 2000-08-01 |
| ES2199251T3 (es) | 2004-02-16 |
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