MX376201B - Compuestos inhibidores de metaloenzima. - Google Patents

Compuestos inhibidores de metaloenzima.

Info

Publication number
MX376201B
MX376201B MX2018008105A MX2018008105A MX376201B MX 376201 B MX376201 B MX 376201B MX 2018008105 A MX2018008105 A MX 2018008105A MX 2018008105 A MX2018008105 A MX 2018008105A MX 376201 B MX376201 B MX 376201B
Authority
MX
Mexico
Prior art keywords
inhibiting compounds
metalloenzyme
metalloenzyme inhibiting
metalloenzymes
mediated
Prior art date
Application number
MX2018008105A
Other languages
English (en)
Other versions
MX2018008105A (es
Inventor
Christopher M Yates
Sammy R Shaver
William J Hoekstra
Original Assignee
Nqp 1598 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nqp 1598 Ltd filed Critical Nqp 1598 Ltd
Publication of MX2018008105A publication Critical patent/MX2018008105A/es
Publication of MX376201B publication Critical patent/MX376201B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)

Abstract

La presente invención describe compuestos que tienen actividad moduladora de metaloenzima, y métodos para tratar enfermedades, trastornos o síntomas de los mismos mediadas por dichas metaloenzimas.
MX2018008105A 2015-12-30 2016-12-29 Compuestos inhibidores de metaloenzima. MX376201B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562273167P 2015-12-30 2015-12-30
PCT/US2016/069217 WO2017117393A1 (en) 2015-12-30 2016-12-29 Metalloenzyme inhibitor compounds

Publications (2)

Publication Number Publication Date
MX2018008105A MX2018008105A (es) 2018-11-12
MX376201B true MX376201B (es) 2025-03-07

Family

ID=59225927

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018008105A MX376201B (es) 2015-12-30 2016-12-29 Compuestos inhibidores de metaloenzima.

Country Status (12)

Country Link
US (1) US10464922B2 (es)
EP (1) EP3397629B1 (es)
JP (1) JP6803923B2 (es)
KR (1) KR102240920B1 (es)
CN (1) CN108779094B (es)
AU (1) AU2016380349B2 (es)
BR (1) BR112018013522A2 (es)
CA (1) CA3006469C (es)
EA (1) EA038421B1 (es)
MX (1) MX376201B (es)
TW (1) TWI623528B (es)
WO (1) WO2017117393A1 (es)

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US10077250B2 (en) 2014-03-19 2018-09-18 Mycovia Pharmaceuticals, Inc. Antifungal compound process
JP6509897B2 (ja) 2014-03-19 2019-05-08 ヴィアメット ファーマスーティカルズ（エヌシー），インコーポレイテッド 抗真菌化合物の調製方法
CN109678791B (zh) 2014-03-19 2022-07-01 美国陶氏益农公司 1-(2,4-二氟苯)-2,2-二氟-2-(5-取代吡啶-2-基)乙酮及制备方法
US10000465B2 (en) 2014-03-19 2018-06-19 Mycovia Pharmaceuticals, Inc. Antifungal compound process
JP6613391B2 (ja) 2014-03-19 2019-12-04 ブイピーエス‐３，インコーポレイテッド ２−（２，４−ジフルオロフェニル）−１，１−ジフルオロ−１−（５−置換ピリジン−２−イル）−３−（１ｈ−テトラゾール−１−イル）プロパン−２−オールおよびその調製工程
EP3119754A4 (en) 2014-03-19 2017-12-13 Viamet Pharmaceuticals, Inc. Antifungal compound process
US9981943B2 (en) 2014-03-19 2018-05-29 Mycovia Pharmaceuticals, Inc. Antifungal compound process
EP3119748A4 (en) 2014-03-19 2017-08-30 Viamet Pharmaceuticals, Inc. Antifungal compound process
EP3119746A4 (en) 2014-03-19 2017-08-16 Viamet Pharmaceuticals, Inc. Antifungal compound process
EP3349753A4 (en) 2015-09-18 2019-01-23 VPS-3, Inc. FUNGICIDE COMPOUNDS AND METHOD OF PREPARING THEREOF
WO2019182743A1 (en) * 2018-03-20 2019-09-26 Innocrin Pharmaceuticals, Inc. Compositions for the treatment of brain tumors
US12357615B2 (en) 2018-10-11 2025-07-15 Kembi Therapeutics Pty Ltd Compositions for the treatment of brain tumors
KR20230175222A (ko) 2021-04-05 2023-12-29 할리아 테라퓨틱스, 인코포레이티드 Nek7 억제제
CN113444131B (zh) * 2021-06-24 2022-10-21 鲁东大学 N-乙酰氨基葡萄糖类化合物及其制备方法和应用
US20250270193A1 (en) * 2021-10-20 2025-08-28 Ohio State Innovation Foundation Arylimidamides for use in treatment of cancers
CN115466227B (zh) * 2022-06-30 2024-07-19 杭州国瑞生物科技有限公司 一种3-(氯甲基)-1-甲基-1h-1,2,4-三唑盐酸盐的制备方法

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Also Published As

Publication number Publication date
KR20180099845A (ko) 2018-09-05
BR112018013522A2 (pt) 2018-12-11
US10464922B2 (en) 2019-11-05
JP6803923B2 (ja) 2020-12-23
MX2018008105A (es) 2018-11-12
EP3397629A4 (en) 2019-06-05
EA038421B1 (ru) 2021-08-26
TW201734000A (zh) 2017-10-01
US20190016700A1 (en) 2019-01-17
KR102240920B1 (ko) 2021-04-16
CA3006469C (en) 2023-01-10
AU2016380349A1 (en) 2018-06-14
EP3397629B1 (en) 2023-04-19
CA3006469A1 (en) 2017-07-06
EA201891539A1 (ru) 2018-12-28
EP3397629A1 (en) 2018-11-07
CN108779094A (zh) 2018-11-09
AU2016380349B2 (en) 2020-10-29
TWI623528B (zh) 2018-05-11
JP2019502755A (ja) 2019-01-31
CN108779094B (zh) 2021-11-16
WO2017117393A1 (en) 2017-07-06

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Legal Events

Date Code Title Description
GB Transfer or rights

Owner name: NQP 1598, LTD.

HC Change of company name or juridical status

Owner name: INTERDIGITAL CE PATENT HOLDINGS

FG Grant or registration