EE05019B1 - Kristalsete orgaaniliste hendite stabiilsed kindla kujuga osakesed - Google Patents

Kristalsete orgaaniliste hendite stabiilsed kindla kujuga osakesed

Info

Publication number
EE05019B1
EE05019B1 EEP200000492A EEP200000492A EE05019B1 EE 05019 B1 EE05019 B1 EE 05019B1 EE P200000492 A EEP200000492 A EE P200000492A EE P200000492 A EEP200000492 A EE P200000492A EE 05019 B1 EE05019 B1 EE 05019B1
Authority
EE
Estonia
Prior art keywords
stable
organic compounds
crystalline organic
particles
stable particles
Prior art date
Application number
EEP200000492A
Other languages
English (en)
Estonian (et)
Inventor
Angeles Uribe Juan
De Gyves Aurelio
Gomez Abraham
Original Assignee
John Claude Savoir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21853984&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE05019(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by John Claude Savoir filed Critical John Claude Savoir
Publication of EE200000492A publication Critical patent/EE200000492A/xx
Publication of EE05019B1 publication Critical patent/EE05019B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
EEP200000492A 1998-02-25 1999-02-10 Kristalsete orgaaniliste hendite stabiilsed kindla kujuga osakesed EE05019B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/030,388 US6287693B1 (en) 1998-02-25 1998-02-25 Stable shaped particles of crystalline organic compounds
PCT/IB1999/000233 WO1999043304A1 (en) 1998-02-25 1999-02-10 Stable shaped particles of crystalline organic compounds

Publications (2)

Publication Number Publication Date
EE200000492A EE200000492A (et) 2002-02-15
EE05019B1 true EE05019B1 (et) 2008-06-16

Family

ID=21853984

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000492A EE05019B1 (et) 1998-02-25 1999-02-10 Kristalsete orgaaniliste hendite stabiilsed kindla kujuga osakesed

Country Status (34)

Country Link
US (7) US6287693B1 (pl)
EP (4) EP2319497B1 (pl)
JP (2) JP4885357B2 (pl)
KR (1) KR100726315B1 (pl)
CN (2) CN1146407C (pl)
AR (3) AR018107A1 (pl)
AT (2) ATE427102T1 (pl)
AU (1) AU747779B2 (pl)
BR (1) BR9908156A (pl)
CA (1) CA2319176C (pl)
CL (1) CL2010001333A1 (pl)
CY (1) CY1118522T1 (pl)
CZ (1) CZ301042B6 (pl)
DE (2) DE69934099T2 (pl)
DK (3) DK1056444T3 (pl)
EE (1) EE05019B1 (pl)
ES (3) ES2275334T3 (pl)
HU (1) HUP0101271A3 (pl)
ID (1) ID26523A (pl)
IL (2) IL137970A0 (pl)
MY (1) MY138375A (pl)
NO (1) NO331804B1 (pl)
NZ (1) NZ505987A (pl)
PE (1) PE20000393A1 (pl)
PL (1) PL196369B1 (pl)
PT (1) PT2085075T (pl)
RU (1) RU2225708C2 (pl)
SA (1) SA99200098B1 (pl)
TR (1) TR200002462T2 (pl)
TW (1) TWI256308B (pl)
UA (1) UA73470C2 (pl)
UY (1) UY25404A1 (pl)
WO (1) WO1999043304A1 (pl)
ZA (1) ZA991058B (pl)

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US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
HRP20041061B1 (hr) 2002-05-16 2015-02-27 Tibotec Pharmaceuticals Ltd. Pseudopolimorfni oblici inhibitora hiv proteaze
US20040028747A1 (en) * 2002-08-06 2004-02-12 Tucker Christopher J. Crystalline drug particles prepared using a controlled precipitation process
US20040028746A1 (en) * 2002-08-06 2004-02-12 Sonke Svenson Crystalline drug particles prepared using a controlled precipitation (recrystallization) process
DK1820494T3 (da) * 2003-06-13 2010-05-25 Skendi Finance Ltd Mikropartikler bestående af estradiol og cholesterol
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
US20050048127A1 (en) * 2003-07-22 2005-03-03 Larry Brown Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
DE602004014805D1 (de) * 2003-12-04 2008-08-14 Pfizer Prod Inc Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten
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US9351924B2 (en) 2011-03-11 2016-05-31 Snu R&Db Foundation Drug delivery system including laminated structure
KR101314126B1 (ko) 2011-03-11 2013-10-04 서울대학교산학협력단 다면체 형상의 약물 전달 시스템
CA2856520C (en) 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
MX366703B (es) 2013-03-15 2019-07-22 Incyte Holdings Corp Heterociclos tricíclicos como inhibidores de la proteína bet.
WO2015095492A1 (en) 2013-12-19 2015-06-25 Incyte Corporation Tricyclic heterocycles as bet protein inhibitors
KR102702503B1 (ko) 2014-04-23 2024-09-05 인사이트 홀딩스 코포레이션 BET 단백질의 저해제로서의 1H-피롤로[2,3-c]피리딘-7(6H)-온 및 피라졸로[3,4-c]피리딘-7(6H)-온
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
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US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
AU2017239645A1 (en) 2016-04-01 2018-10-18 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
PH12021551886A1 (en) 2016-06-20 2023-07-17 Incyte Corp Crystalline solid forms of a bet inhibitor
PL236889B1 (pl) * 2017-10-03 2021-02-22 Univ Warszawski Medyczny Nowa forma krystaliczna bezwodnego 17-β-estradiolu, sposób jej otrzymywania oraz kompozycja farmaceutyczna zawierająca nową formę krystaliczną bezwodnego 17-β-estradiolu i jej zastosowanie
EP3542786A1 (en) * 2018-03-21 2019-09-25 ITF Research Pharma, S.L.U. Progesterone intravaginal devices
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms

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Also Published As

Publication number Publication date
US20040166164A1 (en) 2004-08-26
ES2609284T3 (es) 2017-04-19
ES2275334T3 (es) 2007-06-01
CN1146407C (zh) 2004-04-21
US6663895B2 (en) 2003-12-16
KR100726315B1 (ko) 2007-06-11
UY25404A1 (es) 1999-05-14
US6737081B2 (en) 2004-05-18
NO331804B1 (no) 2012-04-10
DK1772141T3 (da) 2009-07-20
JP2002504507A (ja) 2002-02-12
EP2085075A1 (en) 2009-08-05
US6638536B2 (en) 2003-10-28
DK1056444T3 (da) 2007-03-12
CZ20003047A3 (cs) 2000-11-15
CA2319176C (en) 2007-09-11
IL137970A (en) 2006-10-05
MY138375A (en) 2009-05-29
US6528094B1 (en) 2003-03-04
US6537580B1 (en) 2003-03-25
DE69934099T2 (de) 2007-06-21
ATE345779T1 (de) 2006-12-15
TR200002462T2 (tr) 2000-11-21
RU2225708C2 (ru) 2004-03-20
ZA991058B (en) 1999-08-11
CL2010001333A1 (es) 2011-04-25
CZ301042B6 (cs) 2009-10-21
AU747779B2 (en) 2002-05-23
EP2319497A1 (en) 2011-05-11
EP1056444A1 (en) 2000-12-06
ATE427102T1 (de) 2009-04-15
AR018107A1 (es) 2001-10-31
NO20004241D0 (no) 2000-08-24
UA73470C2 (uk) 2005-08-15
ES2324366T3 (es) 2009-08-05
IL137970A0 (en) 2001-10-31
AU2293699A (en) 1999-09-15
PL196369B1 (pl) 2007-12-31
EP1772141B1 (en) 2009-04-01
PL343170A1 (en) 2001-07-30
HUP0101271A3 (en) 2002-10-28
EE200000492A (et) 2002-02-15
WO1999043304A1 (en) 1999-09-02
PT2085075T (pt) 2017-01-04
JP4885357B2 (ja) 2012-02-29
US20030191101A1 (en) 2003-10-09
AR077168A2 (es) 2011-08-10
DE69940684D1 (de) 2009-05-14
KR20010034540A (ko) 2001-04-25
US6287693B1 (en) 2001-09-11
JP2011241220A (ja) 2011-12-01
HUP0101271A2 (hu) 2001-09-28
EP2085075B1 (en) 2016-09-28
PE20000393A1 (es) 2000-05-04
BR9908156A (pt) 2000-10-31
NO20004241L (no) 2000-08-24
TWI256308B (en) 2006-06-11
US20020168395A1 (en) 2002-11-14
SA99200098B1 (ar) 2006-04-26
NZ505987A (en) 2003-07-25
DE69934099D1 (de) 2007-01-04
HK1155384A1 (en) 2012-05-18
CA2319176A1 (en) 1999-09-02
AR077167A2 (es) 2011-08-10
ID26523A (id) 2001-01-11
CN1524608A (zh) 2004-09-01
US7427413B2 (en) 2008-09-23
HK1036017A1 (en) 2001-12-21
US20030147964A1 (en) 2003-08-07
CN100528140C (zh) 2009-08-19
EP2319497B1 (en) 2012-08-22
DK2085075T3 (en) 2017-01-23
CN1291887A (zh) 2001-04-18
CY1118522T1 (el) 2017-07-12
EP1772141A1 (en) 2007-04-11
EP1056444B1 (en) 2006-11-22

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