ITMI992711A0 - Composti organici - Google Patents

Composti organici

Info

Publication number
ITMI992711A0
ITMI992711A0 IT99MI002711A ITMI992711A ITMI992711A0 IT MI992711 A0 ITMI992711 A0 IT MI992711A0 IT 99MI002711 A IT99MI002711 A IT 99MI002711A IT MI992711 A ITMI992711 A IT MI992711A IT MI992711 A0 ITMI992711 A0 IT MI992711A0
Authority
IT
Italy
Prior art keywords
organic compounds
compounds
organic
Prior art date
Application number
IT99MI002711A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority to IT1999MI002711A priority Critical patent/ITMI992711A1/it
Publication of ITMI992711A0 publication Critical patent/ITMI992711A0/it
Priority to TW089126229A priority patent/TWI246917B/zh
Priority to PE2000001393A priority patent/PE20010991A1/es
Priority to US10/169,035 priority patent/US20030125343A1/en
Priority to AT00985244T priority patent/ATE432069T1/de
Priority to PCT/EP2000/013161 priority patent/WO2001047507A2/en
Priority to CA002394944A priority patent/CA2394944A1/en
Priority to CO00097404A priority patent/CO5271710A1/es
Priority to DE60042283T priority patent/DE60042283D1/de
Priority to CNB008178976A priority patent/CN1304005C/zh
Priority to ARP000106887A priority patent/AR030179A1/es
Priority to BR0016817-3A priority patent/BR0016817A/pt
Priority to EP00985244A priority patent/EP1250140B1/en
Priority to JP2001548102A priority patent/JP2003523325A/ja
Priority to PT00985244T priority patent/PT1250140E/pt
Priority to ES00985244T priority patent/ES2326307T3/es
Priority to AU21719/01A priority patent/AU2171901A/en
Publication of ITMI992711A1 publication Critical patent/ITMI992711A1/it
Priority to HK03101801.4A priority patent/HK1050993A1/zh
Priority to US12/397,374 priority patent/US20090221519A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT1999MI002711A 1999-12-27 1999-12-27 Composti organici ITMI992711A1 (it)

Priority Applications (19)

Application Number Priority Date Filing Date Title
IT1999MI002711A ITMI992711A1 (it) 1999-12-27 1999-12-27 Composti organici
TW089126229A TWI246917B (en) 1999-12-27 2000-12-08 Combinations of a receptor tyrosine kinase inhibitor with an organic compound capable of binding to alpha1-acidic glycoprotein
AU21719/01A AU2171901A (en) 1999-12-27 2000-12-22 Combinations of a receptor tyrosine kinase inhibitor with an organic compound capable of binding to alpha1-acidic glycoprotein
DE60042283T DE60042283D1 (de) 1999-12-27 2000-12-22 Kombination eines abl-, pdgf-rezeptor- und/oder kit rezeptor-tyrosin kinase inhibitors mit einer organischen substanz, die an alpha1-acidisches glycoprotein bindet
BR0016817-3A BR0016817A (pt) 1999-12-27 2000-12-22 Combinações de um inibidor de quinase do receptor de tirosina com um composto orgânico capaz de se ligar à alfa1-glicoproteìna ácida
AT00985244T ATE432069T1 (de) 1999-12-27 2000-12-22 Kombination eines abl-, pdgf-rezeptor- und/oder kit rezeptor-tyrosin kinase inhibitors mit einer organischen substanz, die an alpha1-acidisches glycoprotein bindet
PCT/EP2000/013161 WO2001047507A2 (en) 1999-12-27 2000-12-22 Combinations of receptor tyrosine kinase inhibitor with an a1-acidic glycoprotein binding compound
CA002394944A CA2394944A1 (en) 1999-12-27 2000-12-22 Combinations of a receptor tyrosine kinase inhibitor with an organic compound capable of binding to .alpha.1-acidic glycoprotein
CO00097404A CO5271710A1 (es) 1999-12-27 2000-12-22 Combinanciones de un inhibidor de cinasa de tirosina receptora con un compuesto organico capaz de enlazarse con glicorpoteina acido-a
PE2000001393A PE20010991A1 (es) 1999-12-27 2000-12-22 Combinaciones de un inhibidor de cinasa de tirosina receptora con un compuesto organico capaz de enlazarse con glicoproteina acido-o1
CNB008178976A CN1304005C (zh) 1999-12-27 2000-12-22 受体酪氨酸激酶抑制剂和α1－酸性糖蛋白结合化合物的联合形式
ARP000106887A AR030179A1 (es) 1999-12-27 2000-12-22 Combinaciones de un inhibidor de tirosinquinasa de receptores abl, de pdgf y de kit con un compuesto organico capaz de enlazarse con glicoproteina acido-alfa1, un producto, el uso de dicha combinacion para producir un producto farmaceutico y un producto farmaceutico
US10/169,035 US20030125343A1 (en) 1999-12-27 2000-12-22 Combinations of receptor tyrosine kinase inhibitor with an a1-acidic glycoprotein binding compound
EP00985244A EP1250140B1 (en) 1999-12-27 2000-12-22 Combination ofan abl-, pdgf-receptor- and/or kit receptor-tyrosine kinase inhibitor with an organic compound capable of binding to alpha1-acidic glycoprotein
JP2001548102A JP2003523325A (ja) 1999-12-27 2000-12-22 受容体チロシンキナーゼ阻害剤とα１−酸性糖タンパク質結合性有機化合物との組合せ
PT00985244T PT1250140E (pt) 1999-12-27 2000-12-22 Combinação de um inibidor de abl, receptor pdgf e/ou receptor kit-tirosina quinase com um composto orgânico capaz de se ligar a uma alfa1-glicoproteína ácida
ES00985244T ES2326307T3 (es) 1999-12-27 2000-12-22 Combinacion de un inhibidor del receptor abl, receptor pdgf y/o receptor de kit de la tirosina quinasa con un compuesto organico capaz de unirse a la glicoproteina acida-alfa1.
HK03101801.4A HK1050993A1 (zh) 1999-12-27 2003-03-12 受體酪氨酸激酶抑制劑與能夠結合a1-酸的糖蛋白的有機化合物的組合
US12/397,374 US20090221519A1 (en) 1999-12-27 2009-03-04 Combinations of receptor tyrosine kinase inhibitor with an a1-acidic glycoprotein binding compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI002711A ITMI992711A1 (it) 1999-12-27 1999-12-27 Composti organici

Publications (2)

Publication Number Publication Date
ITMI992711A0 true ITMI992711A0 (it) 1999-12-27
ITMI992711A1 ITMI992711A1 (it) 2001-06-27

Family

ID=11384195

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI002711A ITMI992711A1 (it) 1999-12-27 1999-12-27 Composti organici

Country Status (18)

Country Link
US (2) US20030125343A1 (it)
EP (1) EP1250140B1 (it)
JP (1) JP2003523325A (it)
CN (1) CN1304005C (it)
AR (1) AR030179A1 (it)
AT (1) ATE432069T1 (it)
AU (1) AU2171901A (it)
BR (1) BR0016817A (it)
CA (1) CA2394944A1 (it)
CO (1) CO5271710A1 (it)
DE (1) DE60042283D1 (it)
ES (1) ES2326307T3 (it)
HK (1) HK1050993A1 (it)
IT (1) ITMI992711A1 (it)
PE (1) PE20010991A1 (it)
PT (1) PT1250140E (it)
TW (1) TWI246917B (it)
WO (1) WO2001047507A2 (it)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
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CA2427184A1 (en) * 2000-11-22 2002-05-30 Novartis Ag Combination comprising an agent decreasing vegf activity and an agent decreasing egf activity
AU2002315388A1 (en) 2001-06-21 2003-01-08 Ariad Pharmaceuticals, Inc. Novel phenylamino-pyrimidines and uses thereof
GB0119249D0 (en) 2001-08-07 2001-10-03 Novartis Ag Organic compounds
US7323469B2 (en) 2001-08-07 2008-01-29 Novartis Ag 7H-pyrrolo[2,3-d]pyrimidine derivatives
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
NZ532418A (en) * 2001-10-25 2007-02-23 Novartis Ag Combinations comprising a selective cyclooxygenase-2 inhibitor and a microtubule interfering agent
GB0201508D0 (en) 2002-01-23 2002-03-13 Novartis Ag Organic compounds
EP1487451A4 (en) * 2002-03-21 2007-10-03 Dana Farber Cancer Inst Inc INHIBITION OF CELLULAR DEATH RESPONSES INDUCED BY OXIDATIVE STRESS
AU2007201830C1 (en) * 2002-04-23 2017-09-07 Novartis Pharma Ag High drug load tablet
GB0209265D0 (en) * 2002-04-23 2002-06-05 Novartis Ag Organic compounds
AU2003295320A1 (en) * 2002-06-26 2004-04-08 The Ohio State University Research Foundation The method for reducing inflammation using sti-571 or its salt
AU2003232376A1 (en) * 2002-07-24 2004-02-09 Novartis Ag 4-(4-methylpiperazin-1-ylmethyl)-n-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-benzamide for treating anaplastic thyroid cancer
AU2003250701A1 (en) * 2002-07-31 2004-02-16 Wayne R. Danter Protein tyrosine kinase inhibitors
GB0222514D0 (en) 2002-09-27 2002-11-06 Novartis Ag Organic compounds
WO2004033446A1 (en) * 2002-10-09 2004-04-22 Danter Wayne R Protein tyrosine kinase inhibitors
JP2007523827A (ja) * 2003-08-25 2007-08-23 ダナ−ファーバー　キャンサー　インスティテュート，インコーポレイテッド 混合性白血病遺伝子の再構成を伴う急性リンパ芽球性白血病の処置方法
ATE489109T1 (de) * 2003-09-19 2010-12-15 Novartis Pharma Gmbh Behandlung von gastrointestinalen stromatumoren mit imatinib und midostaurin
TW200517114A (en) * 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
SI1720853T1 (sl) † 2004-02-11 2016-04-29 Natco Pharma Limited "Natco House Nova polimorfna oblika imatinibijevega mesilata in postopek za njeno pripravo
EP1768982A2 (en) 2004-06-29 2007-04-04 Amgen Inc. Pyrolo [2,3-d] pyrimidines that modulate ack1 and lck activity
WO2006017443A2 (en) * 2004-08-02 2006-02-16 Osi Pharmaceuticals, Inc. Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds
AU2005322855B2 (en) 2004-12-30 2012-09-20 Exelixis, Inc. Pyrimidine derivatives as kinase modulators and method of use
US20060275365A1 (en) * 2005-06-07 2006-12-07 Thomas Backensfeld Immediate-release and high-drug-load pharmaceutical formulations of micronised (4-chlorophenyl) [4-(4-pyridylmethyl)phthalazin-1-yl] and salts thereof
US20070059359A1 (en) * 2005-06-07 2007-03-15 Thomas Backensfeld Immediate-release and high-drug-load pharmaceutical formulations of non-micronised (4-chlorophenyl)[4-(4-pyridylmethyl)phthalazin-1-yl] and salts thereof
WO2006136391A2 (en) * 2005-06-23 2006-12-28 Novartis Ag Treatment of solid tumor disease with combinations comprising imatinib and an efflux pump inhibitor
WO2007076035A2 (en) * 2005-12-21 2007-07-05 Abbott Laboratories Anti-viral compounds
RU2441869C2 (ru) * 2005-12-21 2012-02-10 Эбботт Лэборетриз Противовирусные соединения
WO2007081517A2 (en) 2005-12-21 2007-07-19 Abbott Laboratories Anti-viral compounds
WO2007124369A2 (en) * 2006-04-20 2007-11-01 Janssen Pharmaceutica N.V. Method of inhibiting c kit kinase
AU2007269540B2 (en) * 2006-07-05 2013-06-27 Exelixis, Inc. Methods of using IGF1R and Abl kinase modulators
WO2008133753A2 (en) 2006-12-20 2008-11-06 Abbott Laboratories Anti-viral compounds
US8034815B2 (en) 2007-01-11 2011-10-11 Critical Outcome Technologies, Inc. Compounds and method for treatment of cancer
US20080248548A1 (en) * 2007-04-09 2008-10-09 Flynn Daniel L Modulation of protein functionalities
BRPI0817946A2 (pt) * 2007-09-25 2015-05-05 Teva Pharma Composições de imatinibe estável
EP2225226B1 (en) 2007-12-26 2016-08-17 Critical Outcome Technologies, Inc. Compounds and their use in a method for treatment of cancer
BRPI0906475A2 (pt) 2008-01-11 2015-07-14 Natco Pharma Ltd Compostos, processso para a preparação de um composto, composição farmacêutica e uso de um composto
DK2300013T3 (en) 2008-05-21 2017-12-04 Ariad Pharma Inc PHOSPHORUS DERIVATIVES AS KINASE INHIBITORS
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
EP2318406B1 (en) 2008-07-17 2016-01-27 Critical Outcome Technologies, Inc. Thiosemicarbazone inhibitor compounds and cancer treatment methods
CA2744563A1 (en) 2008-12-12 2010-06-17 Ariad Pharmaceuticals, Inc. Azaindole derivatives as kinase inhibitors
ITRM20090578A1 (it) * 2009-11-10 2011-05-11 Noi Per Voi Onlus Nuove composizioni per il trattamento di leucemie chemioresistenti e/o di leucemie potenzialmente chemioresistenti.
CA2999435A1 (en) 2010-04-01 2011-10-06 Critical Outcome Technologies Inc. Compounds and method for treatment of hiv
AR083797A1 (es) 2010-11-10 2013-03-20 Novartis Ag Succinato de dimetil-amida del acido 7-ciclopentil-2-(5-piperazin-1-il-piridin-2-il-amino)-7h-pirrolo-[2,3-d]pirimidin-6-carboxilico, proceso para prepararla, intermediarios de dicha sintesis y proceso de preparacion de los mismos
TR201010618A2 (tr) * 2010-12-20 2012-07-23 Bi̇lgi̇ç Mahmut İmatinib içeren bir oral dozaj formu ve bu oral dozaj formunun üretimi
PL394169A1 (pl) 2011-03-09 2012-09-10 Adamed Spółka Z Ograniczoną Odpowiedzialnością Kompozycja farmaceutyczna metanosulfonianu imatinibu do napełniania jednostkowych postaci dawkowania oraz sposób jej wytwarzania
CN103501612B (zh) 2011-05-04 2017-03-29 阿里亚德医药股份有限公司 抑制表皮生长因子受体导致的癌症中细胞增殖的化合物
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US20150166591A1 (en) 2012-05-05 2015-06-18 Ariad Pharmaceuticals, Inc. Methods and compositions for raf kinase mediated diseases
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
WO2017078647A1 (en) 2015-11-05 2017-05-11 Koçak Farma Ilaç Ve Kimya Sanayi Anonim Şirketi Pharmaceutical compositions of imatinib
EP3257499A1 (en) 2016-06-17 2017-12-20 Vipharm S.A. Process for preparation of imatinib methanesulfonate capsules

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US5587459A (en) * 1994-08-19 1996-12-24 Regents Of The University Of Minnesota Immunoconjugates comprising tyrosine kinase inhibitors
US5750493A (en) * 1995-08-30 1998-05-12 Raymond F. Schinazi Method to improve the biological and antiviral activity of protease inhibitors
US20030069174A1 (en) * 1997-03-10 2003-04-10 Ludwig Pichler Use of human alpha1-acid glycoprotein for producing a pharmaceutical preparation
CO4940418A1 (es) * 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
WO2001004125A1 (fr) * 1999-07-13 2001-01-18 Kyowa Hakko Kogyo Co., Ltd. Derives de staurosporine
EE05351B1 (et) * 1999-12-10 2010-10-15 Pfizer Products Inc. Prrolo[2,3-d]primidiinhendid

Also Published As

Publication number Publication date
CN1414858A (zh) 2003-04-30
DE60042283D1 (de) 2009-07-09
HK1050993A1 (zh) 2003-07-18
AR030179A1 (es) 2003-08-13
ITMI992711A1 (it) 2001-06-27
CN1304005C (zh) 2007-03-14
WO2001047507A3 (en) 2002-04-04
US20090221519A1 (en) 2009-09-03
EP1250140B1 (en) 2009-05-27
ATE432069T1 (de) 2009-06-15
BR0016817A (pt) 2002-10-01
JP2003523325A (ja) 2003-08-05
AU2171901A (en) 2001-07-09
US20030125343A1 (en) 2003-07-03
TWI246917B (en) 2006-01-11
EP1250140A2 (en) 2002-10-23
CA2394944A1 (en) 2001-07-05
WO2001047507A2 (en) 2001-07-05
PT1250140E (pt) 2009-08-24
CO5271710A1 (es) 2003-04-30
PE20010991A1 (es) 2001-10-23
ES2326307T3 (es) 2009-10-07

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