EE04218B1 - Toimeainena klodronaati ja ekstsipiendina ränistatud mikrokristallilist tselluloosi sisaldav farmatseutiline preparaat ning farmatseutilise preparaadi tootmismeetod - Google Patents
Toimeainena klodronaati ja ekstsipiendina ränistatud mikrokristallilist tselluloosi sisaldav farmatseutiline preparaat ning farmatseutilise preparaadi tootmismeetodInfo
- Publication number
- EE04218B1 EE04218B1 EEP200000096A EEP200000096A EE04218B1 EE 04218 B1 EE04218 B1 EE 04218B1 EE P200000096 A EEP200000096 A EE P200000096A EE P200000096 A EEP200000096 A EE P200000096A EE 04218 B1 EE04218 B1 EE 04218B1
- Authority
- EE
- Estonia
- Prior art keywords
- pharmaceutical preparation
- manufacture
- microcrystalline cellulose
- excipient
- active ingredient
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI973733A FI109088B (fi) | 1997-09-19 | 1997-09-19 | Tabletti ja menetelmä sen valmistamiseksi |
PCT/FI1998/000735 WO1999015155A1 (en) | 1997-09-19 | 1998-09-18 | Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient |
Publications (2)
Publication Number | Publication Date |
---|---|
EE200000096A EE200000096A (et) | 2000-12-15 |
EE04218B1 true EE04218B1 (et) | 2004-02-16 |
Family
ID=8549561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200000096A EE04218B1 (et) | 1997-09-19 | 1998-09-18 | Toimeainena klodronaati ja ekstsipiendina ränistatud mikrokristallilist tselluloosi sisaldav farmatseutiline preparaat ning farmatseutilise preparaadi tootmismeetod |
Country Status (31)
Country | Link |
---|---|
EP (1) | EP1027037B1 (cs) |
JP (1) | JP3589977B2 (cs) |
KR (1) | KR20010024184A (cs) |
CN (1) | CN1124130C (cs) |
AT (1) | ATE255410T1 (cs) |
AU (1) | AU737738B2 (cs) |
BG (1) | BG64886B1 (cs) |
BR (1) | BR9812480A (cs) |
CA (1) | CA2301185C (cs) |
CZ (1) | CZ298675B6 (cs) |
DE (3) | DE1027037T1 (cs) |
DK (1) | DK1027037T3 (cs) |
EA (1) | EA002331B1 (cs) |
EE (1) | EE04218B1 (cs) |
ES (1) | ES2212341T3 (cs) |
FI (1) | FI109088B (cs) |
HK (1) | HK1031325A1 (cs) |
HR (1) | HRP20000142B1 (cs) |
HU (1) | HU226118B1 (cs) |
ID (1) | ID24423A (cs) |
IL (1) | IL135130A (cs) |
IS (1) | IS5404A (cs) |
NO (1) | NO327728B1 (cs) |
NZ (1) | NZ503766A (cs) |
PL (1) | PL191166B1 (cs) |
PT (1) | PT1027037E (cs) |
SI (1) | SI1027037T1 (cs) |
SK (1) | SK284088B6 (cs) |
TR (1) | TR200000722T2 (cs) |
UA (1) | UA73078C2 (cs) |
WO (1) | WO1999015155A1 (cs) |
Families Citing this family (86)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6395303B1 (en) | 1996-06-10 | 2002-05-28 | Edward Mendell Co., Inc. | Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose |
SE9901272D0 (sv) * | 1999-04-09 | 1999-04-09 | Astra Ab | New improved formulation |
SE9903345D0 (sv) | 1999-09-17 | 1999-09-17 | Astra Pharma Prod | Novel process |
DE10006125C2 (de) * | 2000-02-11 | 2003-08-28 | Kallies Feinchemie Ag | Modifizierte Mikrocellulose |
US6399101B1 (en) | 2000-03-30 | 2002-06-04 | Mova Pharmaceutical Corp. | Stable thyroid hormone preparations and method of making same |
US8052987B2 (en) | 2000-06-20 | 2011-11-08 | Novartis Pharmaceuticals Corporation | Method of administering bisphosphonates |
EP1591122B1 (en) * | 2000-06-20 | 2012-09-26 | Novartis AG | Method of administering bisphosphonates |
US6753017B2 (en) | 2001-11-07 | 2004-06-22 | Jrs Pharma Lp | Process for preparing dry extracts |
EP1509204A4 (en) * | 2001-11-29 | 2005-07-13 | Rettenmaier & Soehne Gmbh & Co | AGGLOMERATED PARTICLES WITH AN ACTIVE SUBSTANCE PREPARED WITH MELTED MICROCRYSTALLINE CELLULOSE |
GB0209265D0 (en) | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
US20040109889A1 (en) | 2002-12-04 | 2004-06-10 | Bunick Frank J. | Surface treatment composition for soft substrates |
US7862552B2 (en) | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
DK2279731T3 (da) * | 2008-04-23 | 2013-03-18 | Farmasierra Mfg S L | Forbedret farmaceutisk sammensætning, som indeholder ibuprofen og codein |
US8603527B2 (en) * | 2010-10-25 | 2013-12-10 | Signal Pharmaceuticals, Llc | Pharmaceutical formulations of a substituted diaminopurine |
PE20150092A1 (es) * | 2012-02-07 | 2015-02-06 | Biogen Idec Inc | Composiciones farmaceuticas que contienen fumarato de dimetilo |
US9956237B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
US10350227B2 (en) | 2012-05-14 | 2019-07-16 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US9616078B2 (en) | 2012-05-14 | 2017-04-11 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
US9901589B2 (en) | 2012-05-14 | 2018-02-27 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9844559B2 (en) | 2012-05-14 | 2017-12-19 | Antecip Bioventures Ii Llc | Neridronic acid for treating bone marrow lesions |
US8802658B2 (en) | 2012-05-14 | 2014-08-12 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
US9925203B2 (en) | 2012-05-14 | 2018-03-27 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
US9949993B2 (en) | 2012-05-14 | 2018-04-24 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
US10413561B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
US9211257B2 (en) | 2012-05-14 | 2015-12-15 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
US9782421B1 (en) | 2012-05-14 | 2017-10-10 | Antecip Bioventures Ii Llc | Neridronic acid molecular complex for treating complex regional pain syndrome |
US9655908B2 (en) | 2012-05-14 | 2017-05-23 | Antecip Bioventures Ii Llc | Neridronic acid molecular complex for treating complex regional pain syndrome |
US9867840B2 (en) | 2014-05-27 | 2018-01-16 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US10111837B2 (en) | 2012-05-14 | 2018-10-30 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds |
US9770457B2 (en) | 2012-05-14 | 2017-09-26 | Antecip Bioventures Ii Llc | Neridronic acid for treating bone marrow lesion |
US9956234B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
US9289441B2 (en) | 2014-08-08 | 2016-03-22 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
US9662343B2 (en) | 2012-05-14 | 2017-05-30 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US10092581B2 (en) | 2014-05-15 | 2018-10-09 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
US9943531B2 (en) | 2014-08-08 | 2018-04-17 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
US9827192B2 (en) | 2012-05-14 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US8865757B1 (en) | 2014-05-28 | 2014-10-21 | Antecip Bioventures Ii Llp | Therapeutic compositions comprising imidazole and imidazolium compounds |
US9877977B2 (en) | 2012-05-14 | 2018-01-30 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9795622B2 (en) | 2012-05-14 | 2017-10-24 | Antecip Bioventures Ii Llc | Neridronic acid for treating pain associated with a joint |
US20150051175A1 (en) * | 2012-05-14 | 2015-02-19 | Antecip Bioventures Ii Llc | Co-Administration of Steroids and Zoledronic Acid to Prevent and Treat Pain |
US10173986B2 (en) | 2012-05-14 | 2019-01-08 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
US10016446B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating Paget's disease of bone |
US11654152B2 (en) | 2012-05-14 | 2023-05-23 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
US9999629B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9956238B2 (en) | 2014-05-15 | 2018-05-01 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
US9867839B2 (en) | 2012-05-14 | 2018-01-16 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
US9669040B2 (en) | 2012-05-14 | 2017-06-06 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US10034890B2 (en) | 2012-05-14 | 2018-07-31 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9820999B2 (en) | 2012-05-14 | 2017-11-21 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US9895383B2 (en) | 2012-05-14 | 2018-02-20 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US10493085B2 (en) | 2012-05-14 | 2019-12-03 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
US10004756B2 (en) | 2014-05-15 | 2018-06-26 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9707245B2 (en) | 2012-05-14 | 2017-07-18 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US9827256B2 (en) | 2014-05-27 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating lower back pain |
US10028969B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9700570B2 (en) | 2014-05-27 | 2017-07-11 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US10080765B2 (en) | 2012-05-14 | 2018-09-25 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US9694023B2 (en) | 2012-05-14 | 2017-07-04 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
US9675626B2 (en) | 2012-05-14 | 2017-06-13 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9861648B2 (en) | 2012-05-14 | 2018-01-09 | Antecip Boiventures Ii Llc | Osteoclast inhibitors for knee conditions |
US10016445B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US9707247B2 (en) | 2012-05-14 | 2017-07-18 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
US9789128B2 (en) | 2012-05-14 | 2017-10-17 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US10039773B2 (en) | 2012-05-14 | 2018-08-07 | Antecip Bioventures Ii Llc | Neridronic acid for treating arthritis |
US9999628B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
US9717747B2 (en) | 2012-05-14 | 2017-08-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
US10028908B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
US10413560B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
US10463682B2 (en) | 2012-05-14 | 2019-11-05 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating low back pain |
CN102698281B (zh) * | 2012-05-29 | 2013-07-03 | 安吉东来药用辅料有限责任公司 | 海带多糖片剂赋形剂、药物片剂及药物片剂的制备方法 |
CN102671205B (zh) * | 2012-05-29 | 2013-07-10 | 安吉东来药用辅料有限责任公司 | 紫菜多糖片剂赋形剂、药物片剂及药物片剂的制备方法 |
CN102671206B (zh) * | 2012-05-29 | 2013-07-10 | 安吉东来药用辅料有限责任公司 | 低聚果糖片剂赋形剂、药物片剂及药物片剂的制备方法 |
CN102671200B (zh) * | 2012-05-29 | 2013-07-10 | 安吉东来药用辅料有限责任公司 | 低聚异麦芽糖片剂赋形剂、药物片剂及制备方法 |
CN102671204B (zh) * | 2012-05-29 | 2013-07-10 | 安吉东来药用辅料有限责任公司 | 古洛糖片剂赋形剂、药物片剂及药物片剂的制备方法 |
CN102671203B (zh) * | 2012-05-29 | 2013-07-10 | 安吉东来药用辅料有限责任公司 | 裙带菜多糖片剂赋形剂、药物片剂及药物片剂的制备方法 |
CN102698280B (zh) * | 2012-05-29 | 2013-07-10 | 安吉东来药用辅料有限责任公司 | 塔格糖片剂赋形剂、药物片剂及药物片剂的制备方法 |
CN102697744B (zh) * | 2012-05-29 | 2013-11-27 | 安吉东来药用辅料有限责任公司 | 阿洛糖片剂赋形剂、药物片剂及药物片剂的制备方法 |
CN102688206B (zh) * | 2012-05-29 | 2014-08-20 | 石药集团中奇制药技术(石家庄)有限公司 | 一种匹伐他汀钙片及其制备方法 |
US9127069B1 (en) | 2014-06-11 | 2015-09-08 | Antecip Bioventures LLC | Compositions comprising rank/rankl antagonists and related compounds for treating pain |
PT3204386T (pt) | 2014-10-06 | 2021-05-31 | Signal Pharm Llc | Compostos de aminopurina substituída, suas composições e métodos de tratamento com os mesmos |
CN104771761A (zh) * | 2015-03-19 | 2015-07-15 | 深圳国源国药有限公司 | 一种创新药用辅料硅化微晶纤维素及其制备方法 |
CA3019105A1 (en) | 2016-04-01 | 2017-10-05 | Signal Pharmaceuticals, Llc | Solid forms of (1s,4s)-4-(2-(((3s,4r)-3-fluorotetrahydro-2h-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9h-purin-9-yl)-1-methylcyclohexane-1-carboxamide and methods of their use |
NZ746554A (en) | 2016-04-01 | 2023-03-31 | Signal Pharm Llc | Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith |
JP2020536100A (ja) | 2017-10-04 | 2020-12-10 | セルジーン コーポレイション | シス−4−[2−{[(3s,4r)−3−フルオロキサン−4−イル]アミノ}−8−(2,4,6−トリクロロアニリノ)−9h−プリン−9−イル]−1−メチルシクロヘキサン−1−カルボキサミドの製造プロセス |
IL273658B2 (en) | 2017-10-04 | 2024-10-01 | Celgene Corp | Compounds and methods for using cis-4-[2-{[(3S,4R)-3-fluoroxan-4-YL]amino}-8-(2,4,6-trichloroanilino)-9H-purine-9-YL]- 1-Methylcyclohexane-1-carboxamide |
CN110787140A (zh) * | 2018-08-01 | 2020-02-14 | 北京万全德众医药生物技术有限公司 | 比拉斯汀片剂及其制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE60711T1 (de) * | 1986-12-20 | 1991-02-15 | Boehringer Mannheim Gmbh | Clodronat-haltige arzneimittel und verfahren zur herstellung derselben. |
SK281193B6 (sk) * | 1993-05-15 | 2001-01-18 | Roche Diagnostics Gmbh | Tableta so zlepšenou biodostupnosťou účinnej látky, kyseliny klodrónovej, spôsob jej výroby a použitie mikrokryštalickej celulózy |
FI94926C (fi) * | 1993-11-12 | 1995-11-27 | Leiras Oy | Menetelmä klodronaattivalmisteen valmistamiseksi |
US5585115A (en) * | 1995-01-09 | 1996-12-17 | Edward H. Mendell Co., Inc. | Pharmaceutical excipient having improved compressability |
-
1997
- 1997-09-19 FI FI973733A patent/FI109088B/fi not_active IP Right Cessation
-
1998
- 1998-09-18 EP EP98945336A patent/EP1027037B1/en not_active Expired - Lifetime
- 1998-09-18 DE DE1027037T patent/DE1027037T1/de active Pending
- 1998-09-18 ES ES98945336T patent/ES2212341T3/es not_active Expired - Lifetime
- 1998-09-18 PL PL339290A patent/PL191166B1/pl unknown
- 1998-09-18 AT AT98945336T patent/ATE255410T1/de active
- 1998-09-18 PT PT98945336T patent/PT1027037E/pt unknown
- 1998-09-18 CZ CZ20000787A patent/CZ298675B6/cs not_active IP Right Cessation
- 1998-09-18 UA UA2000042105A patent/UA73078C2/uk unknown
- 1998-09-18 AU AU92685/98A patent/AU737738B2/en not_active Expired
- 1998-09-18 SK SK393-2000A patent/SK284088B6/sk not_active IP Right Cessation
- 1998-09-18 TR TR2000/00722T patent/TR200000722T2/xx unknown
- 1998-09-18 CA CA002301185A patent/CA2301185C/en not_active Expired - Lifetime
- 1998-09-18 ID IDW20000735A patent/ID24423A/id unknown
- 1998-09-18 WO PCT/FI1998/000735 patent/WO1999015155A1/en active IP Right Grant
- 1998-09-18 DE DE29824938U patent/DE29824938U1/de not_active Expired - Lifetime
- 1998-09-18 CN CN98809173A patent/CN1124130C/zh not_active Expired - Lifetime
- 1998-09-18 DE DE69820287T patent/DE69820287T2/de not_active Expired - Lifetime
- 1998-09-18 KR KR1020007002955A patent/KR20010024184A/ko active Search and Examination
- 1998-09-18 JP JP2000512526A patent/JP3589977B2/ja not_active Expired - Lifetime
- 1998-09-18 NZ NZ503766A patent/NZ503766A/en not_active IP Right Cessation
- 1998-09-18 EE EEP200000096A patent/EE04218B1/xx unknown
- 1998-09-18 EA EA200000317A patent/EA002331B1/ru not_active IP Right Cessation
- 1998-09-18 DK DK98945336T patent/DK1027037T3/da active
- 1998-09-18 IL IL13513098A patent/IL135130A/en not_active IP Right Cessation
- 1998-09-18 BR BR9812480-3A patent/BR9812480A/pt not_active Application Discontinuation
- 1998-09-18 HU HU0004383A patent/HU226118B1/hu unknown
- 1998-09-18 SI SI9830599T patent/SI1027037T1/xx unknown
-
2000
- 2000-03-13 HR HR20000142A patent/HRP20000142B1/xx not_active IP Right Cessation
- 2000-03-14 IS IS5404A patent/IS5404A/is unknown
- 2000-03-17 NO NO20001417A patent/NO327728B1/no not_active IP Right Cessation
- 2000-03-22 BG BG104265A patent/BG64886B1/bg unknown
-
2001
- 2001-02-02 HK HK01100766A patent/HK1031325A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EE04218B1 (et) | Toimeainena klodronaati ja ekstsipiendina ränistatud mikrokristallilist tselluloosi sisaldav farmatseutiline preparaat ning farmatseutilise preparaadi tootmismeetod | |
EE04800B1 (et) | Oraalne manustamisvorm happes ebapüsiva toimeainetarbeks, toimeaineühik, selle valmistamismeetod ja kasutamine ning meetod oraalse manustamisvormi valmistamiseks | |
BRPI0015567B8 (pt) | composto, composição farmacêutica, forma de unidade de dosagem, uso da composição farmacêutica e método para preparar uma composição farmacêutica | |
EA199900521A1 (ru) | Быстрорастворимая и маскирующая вкус фармацевтическая дозированная лекарственная форма | |
AU3533395A (en) | Oral sustained-release preparation | |
PT1140031E (pt) | Preparacao farmaceutica de libertacao controlada com mesilato de tilidina como substancia activa | |
TNSN03106A1 (fr) | Procede pour la production d'une composition pharmaceutique a faible dose ayant une distribution et activite medicamenteuse uniforme | |
ATE429925T1 (de) | Methoden und pharmazeutische zusammensetzungen zur wundheilung | |
SE9700885D0 (sv) | New pharmaceutical formulation | |
ES2149990T3 (es) | Composiciones farmaceuticas solidas que contienen ingrediente activo de acido (s)-2-(4-isobutilfenil)propionico y celulosa microcristalina y silice coloidal como excipientes. | |
IS3789A7 (is) | Aðferð við framleiðslu lyfjaskammta í föstu formimeð tempraðri losun virks þáttar | |
YU242789A (en) | New compound, 4-fluoro-2-//(4-metoxy-2-pyridin-yl)methylsulphinyl/-1h-benzimidazole and process for obtaining | |
DE69819539D1 (de) | Antithrombotische mittel | |
BR0114395A (pt) | Composição farmacêutica para administração por suprimento via oral | |
AP9901474A0 (en) | Pharmaceutical composition for treating viral diseases. | |
DE69927997D1 (de) | Neuartige pyrimidin-derivate und verfahren zu ihrer herstellung | |
EP1027051A4 (en) | ANTITHROMBOTIC AGENTS | |
SE9900190D0 (sv) | New compounds | |
NZ502807A (en) | Preparation of solid oral dosage forms of alendronic acid (4-amino-1-hydroxybutylidene-1, 1-bisphosphonic acid) | |
ES2170168T3 (es) | Composiciones recubiertas entericamente de derivados de 1,5-benzodiacepina con actividad antagonista o agonista de cck. | |
BG106236A (en) | Melt granulation | |
DE69824410D1 (en) | Antithrombosemittel |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB4A | Valid patent at the end of a year |
Effective date: 20041231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20051231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20061231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20071231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20081231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20101231 |