DK1027037T3 - Farmaceutisk præparat som indeholder clodronat som aktiv ingrediens og forkislet mikrokrystallinsk cellulose som excipiens - Google Patents

Farmaceutisk præparat som indeholder clodronat som aktiv ingrediens og forkislet mikrokrystallinsk cellulose som excipiens

Info

Publication number
DK1027037T3
DK1027037T3 DK98945336T DK98945336T DK1027037T3 DK 1027037 T3 DK1027037 T3 DK 1027037T3 DK 98945336 T DK98945336 T DK 98945336T DK 98945336 T DK98945336 T DK 98945336T DK 1027037 T3 DK1027037 T3 DK 1027037T3
Authority
DK
Denmark
Prior art keywords
microcrystalline cellulose
excipient
silicified microcrystalline
active ingredient
pharmaceutical preparation
Prior art date
Application number
DK98945336T
Other languages
English (en)
Inventor
Eeva-Maria Susanne Rantala
Pertti Tapani Rantala
Veli-Matti Lehtola
Original Assignee
Schering Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Oy filed Critical Schering Oy
Application granted granted Critical
Publication of DK1027037T3 publication Critical patent/DK1027037T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK98945336T 1997-09-19 1998-09-18 Farmaceutisk præparat som indeholder clodronat som aktiv ingrediens og forkislet mikrokrystallinsk cellulose som excipiens DK1027037T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI973733A FI109088B (fi) 1997-09-19 1997-09-19 Tabletti ja menetelmä sen valmistamiseksi
PCT/FI1998/000735 WO1999015155A1 (en) 1997-09-19 1998-09-18 Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient

Publications (1)

Publication Number Publication Date
DK1027037T3 true DK1027037T3 (da) 2004-03-15

Family

ID=8549561

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98945336T DK1027037T3 (da) 1997-09-19 1998-09-18 Farmaceutisk præparat som indeholder clodronat som aktiv ingrediens og forkislet mikrokrystallinsk cellulose som excipiens

Country Status (31)

Country Link
EP (1) EP1027037B1 (da)
JP (1) JP3589977B2 (da)
KR (1) KR20010024184A (da)
CN (1) CN1124130C (da)
AT (1) ATE255410T1 (da)
AU (1) AU737738B2 (da)
BG (1) BG64886B1 (da)
BR (1) BR9812480A (da)
CA (1) CA2301185C (da)
CZ (1) CZ298675B6 (da)
DE (3) DE29824938U1 (da)
DK (1) DK1027037T3 (da)
EA (1) EA002331B1 (da)
EE (1) EE04218B1 (da)
ES (1) ES2212341T3 (da)
FI (1) FI109088B (da)
HK (1) HK1031325A1 (da)
HR (1) HRP20000142B1 (da)
HU (1) HU226118B1 (da)
ID (1) ID24423A (da)
IL (1) IL135130A (da)
IS (1) IS5404A (da)
NO (1) NO327728B1 (da)
NZ (1) NZ503766A (da)
PL (1) PL191166B1 (da)
PT (1) PT1027037E (da)
SI (1) SI1027037T1 (da)
SK (1) SK284088B6 (da)
TR (1) TR200000722T2 (da)
UA (1) UA73078C2 (da)
WO (1) WO1999015155A1 (da)

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SE9903345D0 (sv) 1999-09-17 1999-09-17 Astra Pharma Prod Novel process
DE10006125C2 (de) * 2000-02-11 2003-08-28 Kallies Feinchemie Ag Modifizierte Mikrocellulose
US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
JP4722375B2 (ja) * 2000-06-20 2011-07-13 ノバルティス アーゲー ビホスホネートの投与法
SI1591122T1 (sl) * 2000-06-20 2013-02-28 Novartis Ag Postopek za aplikacijo bisfosfonatov
US6753017B2 (en) 2001-11-07 2004-06-22 Jrs Pharma Lp Process for preparing dry extracts
EP1509204A4 (en) * 2001-11-29 2005-07-13 Rettenmaier & Soehne Gmbh & Co AGGLOMERATED PARTICLES WITH AN ACTIVE SUBSTANCE PREPARED WITH MELTED MICROCRYSTALLINE CELLULOSE
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
US20040109889A1 (en) 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
US8491930B2 (en) * 2008-04-23 2013-07-23 Farmasierra Manufacturing, S.L. Pharmaceutical formulation containing ibuprofen and codeine
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EP2811994A4 (en) * 2012-02-07 2016-01-13 Biogen Ma Inc PHARMACEUTICAL COMPOSITIONS CONTAINING DIMETHYL FUMARATE
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US9795622B2 (en) 2012-05-14 2017-10-24 Antecip Bioventures Ii Llc Neridronic acid for treating pain associated with a joint
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US9700570B2 (en) 2014-05-27 2017-07-11 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9717747B2 (en) 2012-05-14 2017-08-01 Antecip Bioventures Ii Llc Osteoclast inhibitors for knee conditions
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US10413560B2 (en) 2012-05-14 2019-09-17 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
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US10092581B2 (en) 2014-05-15 2018-10-09 Antecip Bioventures Ii Llc Osteoclast inhibitors such as zoledronic acid for low back pain treatment
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US9782421B1 (en) 2012-05-14 2017-10-10 Antecip Bioventures Ii Llc Neridronic acid molecular complex for treating complex regional pain syndrome
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US10173986B2 (en) 2012-05-14 2019-01-08 Antecip Bioventures Ii Llc Methods for the safe administration of imidazole or imidazolium compounds
US9861648B2 (en) 2012-05-14 2018-01-09 Antecip Boiventures Ii Llc Osteoclast inhibitors for knee conditions
US10034890B2 (en) 2012-05-14 2018-07-31 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US10028908B2 (en) 2012-05-14 2018-07-24 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9770457B2 (en) 2012-05-14 2017-09-26 Antecip Bioventures Ii Llc Neridronic acid for treating bone marrow lesion
US9895383B2 (en) 2012-05-14 2018-02-20 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
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US9616078B2 (en) 2012-05-14 2017-04-11 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
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US9925203B2 (en) 2012-05-14 2018-03-27 Antecip Bioventures Ii Llc Compositions for administration of zoledronic acid or related compounds for treating low back pain
US9669040B2 (en) 2012-05-14 2017-06-06 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9943531B2 (en) 2014-08-08 2018-04-17 Antecip Bioventures Ii Llc Osteoclast inhibitors such as zoledronic acid for low back pain treatment
US9707247B2 (en) 2012-05-14 2017-07-18 Antecip Bioventures Ii Llc Compositions for administration of zoledronic acid or related compounds for treating low back pain
US9707245B2 (en) 2012-05-14 2017-07-18 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
US10039773B2 (en) 2012-05-14 2018-08-07 Antecip Bioventures Ii Llc Neridronic acid for treating arthritis
US9999629B2 (en) 2012-05-14 2018-06-19 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
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CN102688206B (zh) * 2012-05-29 2014-08-20 石药集团中奇制药技术(石家庄)有限公司 一种匹伐他汀钙片及其制备方法
CN102698281B (zh) * 2012-05-29 2013-07-03 安吉东来药用辅料有限责任公司 海带多糖片剂赋形剂、药物片剂及药物片剂的制备方法
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CN102698280B (zh) * 2012-05-29 2013-07-10 安吉东来药用辅料有限责任公司 塔格糖片剂赋形剂、药物片剂及药物片剂的制备方法
CN102671206B (zh) * 2012-05-29 2013-07-10 安吉东来药用辅料有限责任公司 低聚果糖片剂赋形剂、药物片剂及药物片剂的制备方法
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CN104771761A (zh) * 2015-03-19 2015-07-15 深圳国源国药有限公司 一种创新药用辅料硅化微晶纤维素及其制备方法
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CN109069512B (zh) 2016-04-01 2022-06-14 西格诺药品有限公司 取代的氨基嘌呤化合物、其组合物以及相关治疗方法
US10590136B2 (en) 2017-10-04 2020-03-17 Celgene Corporation Processes for the preparation of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide
JP7287955B2 (ja) 2017-10-04 2023-06-06 セルジーン コーポレイション シス-4-[2-{[(3s,4r)-3-フルオロオキサン-4-イル]アミノ}-8-(2,4,6-トリクロロアニリノ)-9h-プリン-9-イル]-1-メチルシクロヘキサン-1-カルボキサミドの組成物及び使用方法
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Also Published As

Publication number Publication date
EE200000096A (et) 2000-12-15
FI973733A0 (fi) 1997-09-19
CN1124130C (zh) 2003-10-15
SK284088B6 (sk) 2004-09-08
UA73078C2 (uk) 2005-06-15
PT1027037E (pt) 2004-04-30
IS5404A (is) 2000-03-14
PL191166B1 (pl) 2006-03-31
KR20010024184A (ko) 2001-03-26
TR200000722T2 (tr) 2000-11-21
IL135130A0 (en) 2001-05-20
BG64886B1 (bg) 2006-08-31
CA2301185A1 (en) 1999-04-01
CN1270516A (zh) 2000-10-18
JP2001517616A (ja) 2001-10-09
JP3589977B2 (ja) 2004-11-17
EE04218B1 (et) 2004-02-16
HRP20000142B1 (en) 2004-06-30
ES2212341T3 (es) 2004-07-16
EP1027037A1 (en) 2000-08-16
SK3932000A3 (en) 2000-11-07
EA002331B1 (ru) 2002-04-25
HRP20000142A2 (en) 2000-06-30
ATE255410T1 (de) 2003-12-15
BR9812480A (pt) 2000-09-26
DE1027037T1 (de) 2002-11-28
EP1027037B1 (en) 2003-12-03
AU9268598A (en) 1999-04-12
DE29824938U1 (de) 2003-07-31
FI973733A (fi) 1999-03-20
ID24423A (id) 2000-07-20
HUP0004383A2 (hu) 2001-08-28
SI1027037T1 (en) 2004-04-30
NO20001417D0 (no) 2000-03-17
HK1031325A1 (en) 2001-06-15
HUP0004383A3 (en) 2006-06-28
PL339290A1 (en) 2000-12-04
EA200000317A1 (ru) 2000-10-30
NO327728B1 (no) 2009-09-14
CZ298675B6 (cs) 2007-12-19
IL135130A (en) 2004-09-27
DE69820287T2 (de) 2004-10-14
CZ2000787A3 (cs) 2000-08-16
HU226118B1 (en) 2008-04-28
AU737738B2 (en) 2001-08-30
NO20001417L (no) 2000-05-19
CA2301185C (en) 2006-11-28
BG104265A (en) 2000-11-30
NZ503766A (en) 2002-02-01
DE69820287D1 (de) 2004-01-15
WO1999015155A1 (en) 1999-04-01
FI109088B (fi) 2002-05-31

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