BR9608392A - Preparação multiparticulada de liberação controlada e forma de dosagem em tablete. - Google Patents
Preparação multiparticulada de liberação controlada e forma de dosagem em tablete.Info
- Publication number
- BR9608392A BR9608392A BR9608392-1A BR9608392A BR9608392A BR 9608392 A BR9608392 A BR 9608392A BR 9608392 A BR9608392 A BR 9608392A BR 9608392 A BR9608392 A BR 9608392A
- Authority
- BR
- Brazil
- Prior art keywords
- dosage form
- tablet dosage
- release preparation
- multiparticulate controlled
- controlled
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"PREPARAçãO MULTIPARTICULADA DE LIBERAçãO CONTROLADA E FORMA DE DOSAGEM EM TABLETE". Preparações de liberação controlada multiparticuladas incorporando um sal alcalinizante de potássio, de preferência bicarbonato de potássio, como um ingrediente ativo, que são adequadas para formação de formas de dosagem farmacêuticas para administração oral. Tais formas de dosagens são úteis para suplementação de potássio e para o tratamento de doenças degenerativas dos ossos ou cardiovasculares, por exemplo, osteoporose e hipertensão.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/472,693 US5674529A (en) | 1995-06-06 | 1995-06-06 | Alkalinizing potassium salt controlled release preparations |
PCT/US1996/009016 WO1996039127A1 (en) | 1995-06-06 | 1996-06-06 | Alkalinizing potassium salt controlled release preparations |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9608392A true BR9608392A (pt) | 1999-11-30 |
Family
ID=23876566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9608392-1A BR9608392A (pt) | 1995-06-06 | 1996-06-06 | Preparação multiparticulada de liberação controlada e forma de dosagem em tablete. |
Country Status (18)
Country | Link |
---|---|
US (1) | US5674529A (pt) |
EP (1) | EP0840598A4 (pt) |
JP (1) | JPH11506778A (pt) |
KR (1) | KR19990022537A (pt) |
CN (1) | CN1106837C (pt) |
AR (1) | AR003131A1 (pt) |
AU (1) | AU698784B2 (pt) |
BR (1) | BR9608392A (pt) |
CA (1) | CA2223281A1 (pt) |
CO (1) | CO4700033A1 (pt) |
CZ (1) | CZ288129B6 (pt) |
HU (1) | HUP9900856A2 (pt) |
NO (1) | NO312815B1 (pt) |
NZ (1) | NZ310138A (pt) |
PL (1) | PL323939A1 (pt) |
SK (1) | SK167797A3 (pt) |
WO (1) | WO1996039127A1 (pt) |
ZA (1) | ZA964427B (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4759099A (en) * | 1998-09-21 | 2000-03-23 | Mcneil-Ppc, Inc. | Heat stable antacid and antigas suspensions |
WO2001096260A1 (fr) * | 2000-06-14 | 2001-12-20 | Chisso Corporation | Procede de production de granules bioactifs enrobes |
US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
US20030190343A1 (en) * | 2002-03-05 | 2003-10-09 | Pfizer Inc. | Palatable pharmaceutical compositions for companion animals |
FR2837100B1 (fr) * | 2002-03-18 | 2004-07-23 | Flamel Tech Sa | Comprimes a bases de microcapsules a liberation modifiee |
CN100577164C (zh) | 2002-04-09 | 2010-01-06 | 弗拉梅技术公司 | 可改进释放阿莫西林的微囊含水混悬液形式的口服药物制剂 |
EP1492511B3 (fr) | 2002-04-09 | 2012-05-02 | Flamel Technologies | Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s) |
FR2838647B1 (fr) * | 2002-04-23 | 2006-02-17 | Particules enrobees a liberation prolongee, leur procede de preparation et comprimes les contenant | |
US20040109889A1 (en) * | 2002-12-04 | 2004-06-10 | Bunick Frank J. | Surface treatment composition for soft substrates |
US20050019395A1 (en) * | 2003-04-14 | 2005-01-27 | Gabor Pragai | Formulations of amlodipine maleate |
PT2207526T (pt) | 2007-10-12 | 2018-01-25 | Ferring Int Center Sa | Resumo |
FR2967578B1 (fr) * | 2010-11-18 | 2012-12-28 | Advicenne Pharma | Composition pharmaceutique comportant des sels de citrate et de bicarbonate, et son utilisation pour le traitement de la cystinurie |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3538214A (en) * | 1969-04-22 | 1970-11-03 | Merck & Co Inc | Controlled release medicinal tablets |
US4140756A (en) * | 1976-06-10 | 1979-02-20 | Mead Johnson & Company | Film-coated matrix core tablet |
US4259315A (en) * | 1980-06-13 | 1981-03-31 | A. H. Robins Company, Inc. | Controlled release potassium dosage form |
DK152744C (da) * | 1982-08-13 | 1988-10-31 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat |
DK151608C (da) * | 1982-08-13 | 1988-06-20 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse |
DE3586600T2 (de) * | 1984-02-10 | 1993-02-18 | Benzon Pharma As | Dosierungsform eine vielzahl mit einer diffusionshuelle ueberzogener einheiten enthaltend. |
DK62184D0 (da) * | 1984-02-10 | 1984-02-10 | Benzon As Alfred | Diffusionsovertrukket polydepotpraeparat |
CH658188A5 (de) * | 1984-03-23 | 1986-10-31 | Ciba Geigy Ag | Lagerstabile schnellzerfallende pharmazeutische presslinge. |
CA1270765A (en) * | 1985-02-19 | 1990-06-26 | Charles Hsiao | Controlled release potassium chloride |
GB8519310D0 (en) * | 1985-07-31 | 1985-09-04 | Zyma Sa | Granular active substances |
GB8702411D0 (en) * | 1987-02-03 | 1987-03-11 | Zyma Sa | Swellable pellets |
US4822619A (en) * | 1987-02-18 | 1989-04-18 | Ionor, Inc. | Controlled release pharmaceutical preparation containing a gastrointestinal irritant drug |
US5035898A (en) * | 1987-11-27 | 1991-07-30 | Schering Corporation | Potassium/magnesium supplement |
US5498428A (en) * | 1988-10-21 | 1996-03-12 | The Regents Of The University Of California | Treatment of hypertension by oral administration of potassium bicarbonate |
HU208923B (en) * | 1988-10-21 | 1994-02-28 | Univ California | Process for producing pharmaceutical compositions for treating osteoporosis containing pharmaceutically applicable alkalizing potassium salt |
US5171583A (en) * | 1988-10-21 | 1992-12-15 | The Regents Of The University Of California | Treatment of osteoporosis using potassium bicarbonate |
DE3838094A1 (de) * | 1988-11-10 | 1990-05-17 | Nordmark Arzneimittel Gmbh | Feste pharmazeutische retardform |
US5077051A (en) * | 1990-04-10 | 1991-12-31 | Warner-Lambert Company | Sustained release of active agents from bioadhesive microcapsules |
US5445805A (en) * | 1993-05-06 | 1995-08-29 | Church & Dwight Co., Inc. | Large potassium bicarbonate crystals and process for the preparation thereof |
-
1995
- 1995-06-06 US US08/472,693 patent/US5674529A/en not_active Expired - Lifetime
-
1996
- 1996-05-30 ZA ZA9604427A patent/ZA964427B/xx unknown
- 1996-06-03 AR ARP960102873A patent/AR003131A1/es not_active Application Discontinuation
- 1996-06-06 CN CN96194592A patent/CN1106837C/zh not_active Expired - Fee Related
- 1996-06-06 CO CO96029255A patent/CO4700033A1/es unknown
- 1996-06-06 EP EP96918140A patent/EP0840598A4/en not_active Withdrawn
- 1996-06-06 HU HU9900856A patent/HUP9900856A2/hu unknown
- 1996-06-06 KR KR1019970709018A patent/KR19990022537A/ko not_active Application Discontinuation
- 1996-06-06 WO PCT/US1996/009016 patent/WO1996039127A1/en not_active Application Discontinuation
- 1996-06-06 NZ NZ310138A patent/NZ310138A/en unknown
- 1996-06-06 BR BR9608392-1A patent/BR9608392A/pt not_active IP Right Cessation
- 1996-06-06 PL PL96323939A patent/PL323939A1/xx unknown
- 1996-06-06 CZ CZ19973892A patent/CZ288129B6/cs not_active IP Right Cessation
- 1996-06-06 AU AU60473/96A patent/AU698784B2/en not_active Ceased
- 1996-06-06 SK SK1677-97A patent/SK167797A3/sk unknown
- 1996-06-06 CA CA002223281A patent/CA2223281A1/en not_active Abandoned
- 1996-06-06 JP JP9501435A patent/JPH11506778A/ja not_active Ceased
-
1997
- 1997-12-03 NO NO19975567A patent/NO312815B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0840598A4 (en) | 2001-08-29 |
NO312815B1 (no) | 2002-07-08 |
CZ389297A3 (cs) | 1998-06-17 |
CN1187121A (zh) | 1998-07-08 |
CO4700033A1 (es) | 1998-12-29 |
NO975567D0 (no) | 1997-12-03 |
PL323939A1 (en) | 1998-04-27 |
CA2223281A1 (en) | 1996-12-12 |
AU6047396A (en) | 1996-12-24 |
NZ310138A (en) | 1999-04-29 |
NO975567L (no) | 1998-02-05 |
KR19990022537A (ko) | 1999-03-25 |
US5674529A (en) | 1997-10-07 |
CZ288129B6 (cs) | 2001-04-11 |
WO1996039127A1 (en) | 1996-12-12 |
HUP9900856A2 (hu) | 1999-08-30 |
ZA964427B (en) | 1997-02-24 |
AR003131A1 (es) | 1998-07-08 |
JPH11506778A (ja) | 1999-06-15 |
SK167797A3 (en) | 1998-06-03 |
AU698784B2 (en) | 1998-11-05 |
EP0840598A1 (en) | 1998-05-13 |
CN1106837C (zh) | 2003-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Decision: intention to grant | ||
FG9A | Patent or certificate of addition granted | ||
B24C | Patent annual fee: request for for restoration | ||
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |