HK1031325A1 - Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient - Google Patents

Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient

Info

Publication number
HK1031325A1
HK1031325A1 HK01100766A HK01100766A HK1031325A1 HK 1031325 A1 HK1031325 A1 HK 1031325A1 HK 01100766 A HK01100766 A HK 01100766A HK 01100766 A HK01100766 A HK 01100766A HK 1031325 A1 HK1031325 A1 HK 1031325A1
Authority
HK
Hong Kong
Prior art keywords
clodronate
microcrystalline cellulose
excipient
silicified microcrystalline
active ingredient
Prior art date
Application number
HK01100766A
Other languages
English (en)
Inventor
Veli-Matti Lehtola
Eeva-Maria Susanne Rantala
Pertti Tapani Rantala
Original Assignee
Schering Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Oy filed Critical Schering Oy
Publication of HK1031325A1 publication Critical patent/HK1031325A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HK01100766A 1997-09-19 2001-02-02 Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient HK1031325A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI973733A FI109088B (fi) 1997-09-19 1997-09-19 Tabletti ja menetelmä sen valmistamiseksi
PCT/FI1998/000735 WO1999015155A1 (en) 1997-09-19 1998-09-18 Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient

Publications (1)

Publication Number Publication Date
HK1031325A1 true HK1031325A1 (en) 2001-06-15

Family

ID=8549561

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01100766A HK1031325A1 (en) 1997-09-19 2001-02-02 Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient

Country Status (31)

Country Link
EP (1) EP1027037B1 (xx)
JP (1) JP3589977B2 (xx)
KR (1) KR20010024184A (xx)
CN (1) CN1124130C (xx)
AT (1) ATE255410T1 (xx)
AU (1) AU737738B2 (xx)
BG (1) BG64886B1 (xx)
BR (1) BR9812480A (xx)
CA (1) CA2301185C (xx)
CZ (1) CZ298675B6 (xx)
DE (3) DE29824938U1 (xx)
DK (1) DK1027037T3 (xx)
EA (1) EA002331B1 (xx)
EE (1) EE04218B1 (xx)
ES (1) ES2212341T3 (xx)
FI (1) FI109088B (xx)
HK (1) HK1031325A1 (xx)
HR (1) HRP20000142B1 (xx)
HU (1) HU226118B1 (xx)
ID (1) ID24423A (xx)
IL (1) IL135130A (xx)
IS (1) IS5404A (xx)
NO (1) NO327728B1 (xx)
NZ (1) NZ503766A (xx)
PL (1) PL191166B1 (xx)
PT (1) PT1027037E (xx)
SI (1) SI1027037T1 (xx)
SK (1) SK284088B6 (xx)
TR (1) TR200000722T2 (xx)
UA (1) UA73078C2 (xx)
WO (1) WO1999015155A1 (xx)

Families Citing this family (86)

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SE9903345D0 (sv) 1999-09-17 1999-09-17 Astra Pharma Prod Novel process
DE10006125C2 (de) * 2000-02-11 2003-08-28 Kallies Feinchemie Ag Modifizierte Mikrocellulose
US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
JP4722375B2 (ja) * 2000-06-20 2011-07-13 ノバルティス アーゲー ビホスホネートの投与法
SI1591122T1 (sl) * 2000-06-20 2013-02-28 Novartis Ag Postopek za aplikacijo bisfosfonatov
US6753017B2 (en) 2001-11-07 2004-06-22 Jrs Pharma Lp Process for preparing dry extracts
EP1509204A4 (en) * 2001-11-29 2005-07-13 Rettenmaier & Soehne Gmbh & Co AGGLOMERATED PARTICLES WITH AN ACTIVE SUBSTANCE PREPARED WITH MELTED MICROCRYSTALLINE CELLULOSE
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
US20040109889A1 (en) 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
US8491930B2 (en) * 2008-04-23 2013-07-23 Farmasierra Manufacturing, S.L. Pharmaceutical formulation containing ibuprofen and codeine
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EP2811994A4 (en) * 2012-02-07 2016-01-13 Biogen Ma Inc PHARMACEUTICAL COMPOSITIONS CONTAINING DIMETHYL FUMARATE
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US10080765B2 (en) 2012-05-14 2018-09-25 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
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US9675626B2 (en) 2012-05-14 2017-06-13 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US10413560B2 (en) 2012-05-14 2019-09-17 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
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US10016446B2 (en) 2012-05-14 2018-07-10 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating Paget's disease of bone
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US10092581B2 (en) 2014-05-15 2018-10-09 Antecip Bioventures Ii Llc Osteoclast inhibitors such as zoledronic acid for low back pain treatment
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US10463682B2 (en) 2012-05-14 2019-11-05 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating low back pain
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US9820999B2 (en) 2012-05-14 2017-11-21 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
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US9956238B2 (en) 2014-05-15 2018-05-01 Antecip Bioventures Ii Llc Compositions for administration of zoledronic acid or related compounds for treating low back pain
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US9861648B2 (en) 2012-05-14 2018-01-09 Antecip Boiventures Ii Llc Osteoclast inhibitors for knee conditions
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US9895383B2 (en) 2012-05-14 2018-02-20 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
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US9707247B2 (en) 2012-05-14 2017-07-18 Antecip Bioventures Ii Llc Compositions for administration of zoledronic acid or related compounds for treating low back pain
US9707245B2 (en) 2012-05-14 2017-07-18 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
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US9999629B2 (en) 2012-05-14 2018-06-19 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
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CN102671200B (zh) * 2012-05-29 2013-07-10 安吉东来药用辅料有限责任公司 低聚异麦芽糖片剂赋形剂、药物片剂及制备方法
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CN102688206B (zh) * 2012-05-29 2014-08-20 石药集团中奇制药技术（石家庄）有限公司 一种匹伐他汀钙片及其制备方法
CN102698281B (zh) * 2012-05-29 2013-07-03 安吉东来药用辅料有限责任公司 海带多糖片剂赋形剂、药物片剂及药物片剂的制备方法
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CN102697744B (zh) * 2012-05-29 2013-11-27 安吉东来药用辅料有限责任公司 阿洛糖片剂赋形剂、药物片剂及药物片剂的制备方法
CN102698280B (zh) * 2012-05-29 2013-07-10 安吉东来药用辅料有限责任公司 塔格糖片剂赋形剂、药物片剂及药物片剂的制备方法
CN102671206B (zh) * 2012-05-29 2013-07-10 安吉东来药用辅料有限责任公司 低聚果糖片剂赋形剂、药物片剂及药物片剂的制备方法
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CN104771761A (zh) * 2015-03-19 2015-07-15 深圳国源国药有限公司 一种创新药用辅料硅化微晶纤维素及其制备方法
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CN109069512B (zh) 2016-04-01 2022-06-14 西格诺药品有限公司 取代的氨基嘌呤化合物、其组合物以及相关治疗方法
US10590136B2 (en) 2017-10-04 2020-03-17 Celgene Corporation Processes for the preparation of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide
JP7287955B2 (ja) 2017-10-04 2023-06-06 セルジーン コーポレイション シス－４－［２－｛［（３ｓ，４ｒ）－３－フルオロオキサン－４－イル］アミノ｝－８－（２，４，６－トリクロロアニリノ）－９ｈ－プリン－９－イル］－１－メチルシクロヘキサン－１－カルボキサミドの組成物及び使用方法
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Also Published As

Publication number Publication date
EE200000096A (et) 2000-12-15
FI973733A0 (fi) 1997-09-19
CN1124130C (zh) 2003-10-15
SK284088B6 (sk) 2004-09-08
UA73078C2 (uk) 2005-06-15
PT1027037E (pt) 2004-04-30
IS5404A (is) 2000-03-14
PL191166B1 (pl) 2006-03-31
KR20010024184A (ko) 2001-03-26
TR200000722T2 (tr) 2000-11-21
IL135130A0 (en) 2001-05-20
BG64886B1 (bg) 2006-08-31
CA2301185A1 (en) 1999-04-01
CN1270516A (zh) 2000-10-18
JP2001517616A (ja) 2001-10-09
JP3589977B2 (ja) 2004-11-17
EE04218B1 (et) 2004-02-16
HRP20000142B1 (en) 2004-06-30
ES2212341T3 (es) 2004-07-16
EP1027037A1 (en) 2000-08-16
SK3932000A3 (en) 2000-11-07
EA002331B1 (ru) 2002-04-25
HRP20000142A2 (en) 2000-06-30
DK1027037T3 (da) 2004-03-15
ATE255410T1 (de) 2003-12-15
BR9812480A (pt) 2000-09-26
DE1027037T1 (de) 2002-11-28
EP1027037B1 (en) 2003-12-03
AU9268598A (en) 1999-04-12
DE29824938U1 (de) 2003-07-31
FI973733A (fi) 1999-03-20
ID24423A (id) 2000-07-20
HUP0004383A2 (hu) 2001-08-28
SI1027037T1 (en) 2004-04-30
NO20001417D0 (no) 2000-03-17
HUP0004383A3 (en) 2006-06-28
PL339290A1 (en) 2000-12-04
EA200000317A1 (ru) 2000-10-30
NO327728B1 (no) 2009-09-14
CZ298675B6 (cs) 2007-12-19
IL135130A (en) 2004-09-27
DE69820287T2 (de) 2004-10-14
CZ2000787A3 (cs) 2000-08-16
HU226118B1 (en) 2008-04-28
AU737738B2 (en) 2001-08-30
NO20001417L (no) 2000-05-19
CA2301185C (en) 2006-11-28
BG104265A (en) 2000-11-30
NZ503766A (en) 2002-02-01
DE69820287D1 (de) 2004-01-15
WO1999015155A1 (en) 1999-04-01
FI109088B (fi) 2002-05-31

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