CA2191855A1 - Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients - Google Patents

Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients

Info

Publication number
CA2191855A1
CA2191855A1 CA002191855A CA2191855A CA2191855A1 CA 2191855 A1 CA2191855 A1 CA 2191855A1 CA 002191855 A CA002191855 A CA 002191855A CA 2191855 A CA2191855 A CA 2191855A CA 2191855 A1 CA2191855 A1 CA 2191855A1
Authority
CA
Canada
Prior art keywords
isobutylphenyl
active ingredient
propionic acid
excipients
solid pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002191855A
Other languages
French (fr)
Other versions
CA2191855C (en
Inventor
Federico Stroppolo
Daniele Bonadeo
Alberto Pagano
Annibale Gazzaniga (Deceased)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Federico Stroppolo
Daniele Bonadeo
Alberto Pagano
Annibale Gazzaniga (Deceased)
Gazzaniga, Giovanni
Marabelli, Cisella
Zambon Group S.P.A.
Gazzaniga, Paolo
Zambon S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI941262A external-priority patent/IT1270239B/en
Application filed by Federico Stroppolo, Daniele Bonadeo, Alberto Pagano, Annibale Gazzaniga (Deceased), Gazzaniga, Giovanni, Marabelli, Cisella, Zambon Group S.P.A., Gazzaniga, Paolo, Zambon S.P.A. filed Critical Federico Stroppolo
Publication of CA2191855A1 publication Critical patent/CA2191855A1/en
Application granted granted Critical
Publication of CA2191855C publication Critical patent/CA2191855C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A solid pharmaceutical composition suitable for the preparation of pharmaceutical forms such as tablets, sachets and capsules, containing (S)-2-(4-isobutylphenyl)propionic acid as active ingredient, is described.
CA002191855A 1994-06-17 1995-05-26 Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients Expired - Lifetime CA2191855C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI941262A IT1270239B (en) 1994-06-17 1994-06-17 SOLID PHARMACEUTICAL COMPOSITION CONTAINING ACID (S) -2- (4- ISOBUTYLPHENYL) PROPIONIC AS ACTIVE INGREDIENT
ITMI94A001262 1994-06-17
PCT/EP1995/002010 WO1995035104A1 (en) 1994-06-17 1995-05-26 Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients

Publications (2)

Publication Number Publication Date
CA2191855A1 true CA2191855A1 (en) 1995-12-28
CA2191855C CA2191855C (en) 2006-08-01

Family

ID=36764259

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002191855A Expired - Lifetime CA2191855C (en) 1994-06-17 1995-05-26 Solid pharmaceutical compositions containing (s)-2-(4-isobutylphenyl)propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients

Country Status (1)

Country Link
CA (1) CA2191855C (en)

Also Published As

Publication number Publication date
CA2191855C (en) 2006-08-01

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Effective date: 20150526