EE03562B1 - 4-ndas asendis kaksikasendatud amiinradikaali sisaldavad uudsed antikonvulsiivse toimega 1-ar(alk)üülimidasoliin-2-oonid ning nende valmistamise meetod - Google Patents
4-ndas asendis kaksikasendatud amiinradikaali sisaldavad uudsed antikonvulsiivse toimega 1-ar(alk)üülimidasoliin-2-oonid ning nende valmistamise meetodInfo
- Publication number
- EE03562B1 EE03562B1 EE9800063A EE9800063A EE03562B1 EE 03562 B1 EE03562 B1 EE 03562B1 EE 9800063 A EE9800063 A EE 9800063A EE 9800063 A EE9800063 A EE 9800063A EE 03562 B1 EE03562 B1 EE 03562B1
- Authority
- EE
- Estonia
- Prior art keywords
- ylimidazolin
- alk
- preparation
- amine radical
- ones containing
- Prior art date
Links
- 230000001773 anti-convulsant effect Effects 0.000 title 1
- 239000001961 anticonvulsive agent Substances 0.000 title 1
- 229960003965 antiepileptics Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19532668A DE19532668A1 (de) | 1995-09-05 | 1995-09-05 | Neue, antikonvulsiv wirkende 1-Ar(alk)yl-imidazolin-2-one, die in 4-Stellung einen disubstituierten Amin-Rest enthalten, und Verfahren zu deren Herstellung |
| PCT/EP1996/003295 WO1997009314A1 (de) | 1995-09-05 | 1996-07-26 | Neue, antikonvulsiv wirkende 1-ar(alk)yl-imidazolin-2-one, die in 4-stellung einen disubstituierten amin-rest enthalten, und verfahren zu deren herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE9800063A EE9800063A (et) | 1998-08-17 |
| EE03562B1 true EE03562B1 (et) | 2001-12-17 |
Family
ID=7771261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EE9800063A EE03562B1 (et) | 1995-09-05 | 1996-07-26 | 4-ndas asendis kaksikasendatud amiinradikaali sisaldavad uudsed antikonvulsiivse toimega 1-ar(alk)üülimidasoliin-2-oonid ning nende valmistamise meetod |
Country Status (31)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19721580A1 (de) * | 1997-05-23 | 1998-11-26 | Dresden Arzneimittel | Verwendung von 1-Ar(alk)yl-imidazolin-2-one zur Behandlung von Angst- und Spannungszuständen |
| US20050070537A1 (en) * | 2002-10-10 | 2005-03-31 | Chris Rundfeldt | Use of dihydroimidazolones for the treatment of dogs |
| RU2354377C2 (ru) * | 2003-07-11 | 2009-05-10 | Берингер Ингельхайм Ветмедика Гмбх | Способ лечения или предупреждения заболеваний центральной нервной системы с использованием соединений, обладающих селективностью в отношении альфа-3-субъединицы бензодиазепинового рецептора |
| EP2093218A1 (en) * | 2008-02-22 | 2009-08-26 | Ruggero Fariello | Arylalkyl substituted imidazolidinones |
| AR089646A1 (es) | 2011-08-12 | 2014-09-10 | Boehringer Ingelheim Vetmed | Inhibidores de corrientes funny (if) para utilizar en un metodo de tratamiento y prevencion de la insuficiencia cardiaca en felinos |
| US9820988B2 (en) | 2014-03-24 | 2017-11-21 | Boehringer Ingelheim Vetmedica Gmbh | Treatment of epileptic disorders in feline animals |
| IT202100000782A1 (it) | 2021-01-18 | 2022-07-18 | Procos Spa | Processo per la sintesi di imepitoina |
| EP4553066A1 (en) | 2023-11-10 | 2025-05-14 | Justesa Imagen S.A.U. | Improved process for the synthesis of imepitoin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE790380A (fr) | 1971-10-21 | 1973-04-20 | American Cyanamid Co | Nouvelles (p-chloro) phenyl-1 methyl-3 imidazolidines, 2,4-disubstituees utiles notamment comme agents diuretiques antialdosterone et leur procede de preparation |
| US4044021A (en) * | 1971-10-21 | 1977-08-23 | American Cyanamid Company | Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism |
| US3932452A (en) * | 1975-02-07 | 1976-01-13 | Morton-Norwich Products, Inc. | 1-Arylmethyl-2-imidazolidinones |
-
1995
- 1995-09-05 DE DE19532668A patent/DE19532668A1/de not_active Ceased
-
1996
- 1996-07-26 ES ES96927607T patent/ES2208758T3/es not_active Expired - Lifetime
- 1996-07-26 JP JP51080097A patent/JP4030578B2/ja not_active Expired - Lifetime
- 1996-07-26 CN CN96197801A patent/CN1103762C/zh not_active Expired - Lifetime
- 1996-07-26 PT PT96927607T patent/PT863880E/pt unknown
- 1996-07-26 TR TR1998/00476T patent/TR199800476T1/xx unknown
- 1996-07-26 AT AT96927607T patent/ATE254606T1/de active
- 1996-07-26 PL PL96325413A patent/PL188287B1/pl unknown
- 1996-07-26 EP EP96927607A patent/EP0863880B1/de not_active Expired - Lifetime
- 1996-07-26 BR BR9610359A patent/BR9610359A/pt active IP Right Grant
- 1996-07-26 EA EA199800271A patent/EA000535B1/ru not_active IP Right Cessation
- 1996-07-26 IL IL12333396A patent/IL123333A/en not_active IP Right Cessation
- 1996-07-26 NZ NZ315624A patent/NZ315624A/en not_active IP Right Cessation
- 1996-07-26 WO PCT/EP1996/003295 patent/WO1997009314A1/de active IP Right Grant
- 1996-07-26 UA UA98041717A patent/UA46790C2/uk unknown
- 1996-07-26 SK SK216-98A patent/SK284868B6/sk not_active IP Right Cessation
- 1996-07-26 DE DE59610827T patent/DE59610827D1/de not_active Expired - Lifetime
- 1996-07-26 EE EE9800063A patent/EE03562B1/xx unknown
- 1996-07-26 AU AU67375/96A patent/AU700602B2/en not_active Expired
- 1996-07-26 CZ CZ1998661A patent/CZ291839B6/cs not_active IP Right Cessation
- 1996-07-26 GE GEAP19964221A patent/GEP20022652B/en unknown
- 1996-07-26 DK DK96927607T patent/DK0863880T3/da active
- 1996-07-26 HU HU9802941A patent/HU225956B1/hu unknown
- 1996-08-19 ZA ZA967014A patent/ZA967014B/xx unknown
- 1996-09-03 TW TW085110749A patent/TW422838B/zh not_active IP Right Cessation
- 1996-09-04 AR ARP960104226A patent/AR003502A1/es active IP Right Grant
- 1996-09-05 CA CA002184871A patent/CA2184871C/en not_active Expired - Lifetime
-
1998
- 1998-02-27 BG BG102287A patent/BG63917B1/bg unknown
- 1998-03-02 NO NO19980906A patent/NO313829B1/no not_active IP Right Cessation
- 1998-04-03 LT LT98-047A patent/LT4482B/lt not_active IP Right Cessation
-
2013
- 2013-08-07 LU LU92263C patent/LU92263I2/fr unknown
- 2013-08-13 FR FR13C0049C patent/FR13C0049I2/fr active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20021231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20031231 |
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| GB1A | Change in the ownership or in the address of the owner | ||
| KB4A | Valid patent at the end of a year |
Effective date: 20041231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20051231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20061231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20071231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20081231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20091231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
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| GB1A | Change in the ownership or in the address of the owner | ||
| HC1A | Change of owner name |