DK1095941T3 - Fremgangsmåde og krystalformer for 2-methyl-thieno-benzodiazepin - Google Patents

Fremgangsmåde og krystalformer for 2-methyl-thieno-benzodiazepin

Info

Publication number
DK1095941T3
DK1095941T3 DK00203573T DK00203573T DK1095941T3 DK 1095941 T3 DK1095941 T3 DK 1095941T3 DK 00203573 T DK00203573 T DK 00203573T DK 00203573 T DK00203573 T DK 00203573T DK 1095941 T3 DK1095941 T3 DK 1095941T3
Authority
DK
Denmark
Prior art keywords
benzodiazepine
thieno
methyl
crystal forms
crystal
Prior art date
Application number
DK00203573T
Other languages
English (en)
Inventor
Charles Arthur Bunnell
Barry Arnold Hendriksen
Samuel Dean Larsen
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23621056&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1095941(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK1095941T3 publication Critical patent/DK1095941T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
DK00203573T 1995-03-24 1996-03-22 Fremgangsmåde og krystalformer for 2-methyl-thieno-benzodiazepin DK1095941T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40956695A 1995-03-24 1995-03-24
EP96302000A EP0733635B1 (en) 1995-03-24 1996-03-22 Crystal forms of a thieno(2,3-B)(1,5) benzodiazepine derivative and process for their preparation

Publications (1)

Publication Number Publication Date
DK1095941T3 true DK1095941T3 (da) 2004-02-16

Family

ID=23621056

Family Applications (4)

Application Number Title Priority Date Filing Date
DK00203573T DK1095941T3 (da) 1995-03-24 1996-03-22 Fremgangsmåde og krystalformer for 2-methyl-thieno-benzodiazepin
DK96302000T DK0733635T3 (da) 1995-03-24 1996-03-22 Krystalformer af et thieno[2,3-b] [1,5]benzodiazepin-derivat og fremgangsmåde til deres fremstilling
DK03077455T DK1445259T3 (da) 1995-03-24 1996-03-22 Anvendelse af krystalformer for 2-methyl-thieno-benzodiazepin
DK108997A DK108997A (da) 1995-03-24 1997-09-23 Fremstilling og krystalformer af 2-methylthien-benzodiazepin

Family Applications After (3)

Application Number Title Priority Date Filing Date
DK96302000T DK0733635T3 (da) 1995-03-24 1996-03-22 Krystalformer af et thieno[2,3-b] [1,5]benzodiazepin-derivat og fremgangsmåde til deres fremstilling
DK03077455T DK1445259T3 (da) 1995-03-24 1996-03-22 Anvendelse af krystalformer for 2-methyl-thieno-benzodiazepin
DK108997A DK108997A (da) 1995-03-24 1997-09-23 Fremstilling og krystalformer af 2-methylthien-benzodiazepin

Country Status (49)

Country Link
US (1) US5736541A (da)
EP (3) EP1095941B1 (da)
JP (1) JPH11502535A (da)
KR (1) KR100399688B1 (da)
CN (1) CN1065536C (da)
AP (1) AP828A (da)
AR (2) AR002719A1 (da)
AT (4) ATE251627T1 (da)
AU (1) AU706471B2 (da)
BG (1) BG62619B1 (da)
BR (1) BR9607790A (da)
CA (1) CA2214005C (da)
CH (1) CH690579A5 (da)
CO (1) CO4650278A1 (da)
CZ (1) CZ292688B6 (da)
DE (4) DE69636313T2 (da)
DK (4) DK1095941T3 (da)
EA (1) EA000149B1 (da)
EE (1) EE03489B1 (da)
EG (1) EG23659A (da)
ES (3) ES2208220T3 (da)
FI (1) FI973750A (da)
GB (1) GB2313835B (da)
HK (1) HK1013988A1 (da)
HU (1) HU224989B1 (da)
IL (1) IL117610A (da)
IS (1) IS1896B (da)
LT (1) LT4349B (da)
LU (1) LU90096B1 (da)
LV (1) LV12018B (da)
MY (1) MY114701A (da)
NO (1) NO314663B1 (da)
NZ (1) NZ306110A (da)
OA (1) OA10510A (da)
PA (1) PA8353701A1 (da)
PE (1) PE44897A1 (da)
PL (1) PL183723B1 (da)
PT (3) PT1095941E (da)
RO (1) RO118872B1 (da)
SE (1) SE9703205L (da)
SI (4) SI0733635T1 (da)
SK (1) SK284143B6 (da)
SV (1) SV1996000031A (da)
TR (1) TR199701017T1 (da)
TW (2) TW513432B (da)
UA (1) UA44765C2 (da)
WO (1) WO1996030375A1 (da)
YU (1) YU49478B (da)
ZA (2) ZA962342B (da)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
AU7013196A (en) * 1995-09-29 1997-04-17 Eli Lilly And Company Method for treating a tic disorder
UA57727C2 (uk) * 1996-03-11 2003-07-15 Елі Ліллі Енд Компані Спосіб лікування надмірної агресивності
JP2001517202A (ja) * 1996-03-25 2001-10-02 イーライ・リリー・アンド・カンパニー 痛み処置方法
JP2000507546A (ja) * 1996-03-25 2000-06-20 イーライ・リリー・アンド・カンパニー 麻酔方法
WO1997035582A1 (en) * 1996-03-25 1997-10-02 Eli Lilly And Company Method for treating migraine pain
US5945416A (en) * 1996-03-25 1999-08-31 Eli Lilly And Company Method for treating pain
KR100516088B1 (ko) * 1996-09-23 2005-09-22 일라이 릴리 앤드 캄파니 올란자핀 이수화물 ｄ
ZA978515B (en) * 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
WO1998046596A1 (en) * 1997-04-15 1998-10-22 Eli Lilly And Company Method for providing neuro-protective effects
EP1155696B1 (en) * 1997-04-15 2004-03-03 Eli Lilly And Company Use of olanzapine for the manufacture of a medicament for neuroprotection
ZA982917B (en) * 1997-04-15 1999-10-06 Lilly Co Eli Method for treating cerebral focal stroke.
US20030022889A1 (en) * 1997-04-15 2003-01-30 Bymaster Franklin P. Method for providing neuro-protective effects
USRE43932E1 (en) 1997-07-18 2013-01-15 Novartis Ag Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
US6617321B2 (en) 1997-09-30 2003-09-09 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
SK285944B6 (sk) * 1998-09-30 2007-11-02 Eli Lilly And Company Pamoátová soľ olanzapínu a jej solváty
FR2802101B1 (fr) 1999-12-10 2003-02-28 Aventis Pharma Sa Association de cymemazine et d'un neuroleptique atypique
US6348458B1 (en) 1999-12-28 2002-02-19 U & I Pharmaceuticals Ltd. Polymorphic forms of olanzapine
US7022698B2 (en) 1999-12-28 2006-04-04 U & I Pharmaceuticals, Ltd. Pharmaceutical compositions containing new polymorphic forms of olanzapine and uses thereof
CA2395774C (en) * 1999-12-28 2009-09-15 Cipla Limited New polymorphic forms of olanzapine
IL154688A0 (en) * 2000-08-31 2003-09-17 Reddys Lab Ltd Dr Hydrates of olanzapine and processes for the preparation thereof
WO2002019998A2 (en) * 2000-09-08 2002-03-14 Eli Lilly And Company A method of treating weight gain associated with atypical antipsychotic use
US6740753B2 (en) 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
CA2464306A1 (en) * 2001-10-29 2003-05-08 Dr. Reddy's Laboratories Ltd. Olanzapine dihydrate-ii a process for its preparation and use thereof
JP4530664B2 (ja) * 2001-12-24 2010-08-25 サン・ファーマシューティカル・インダストリーズ・リミテッド ２−メチル−４−（４−メチル−１−ピペラジニル）−１０Ｈ−チエノ［２，３−ｂ］［１，５］ベンゾジアゼピンの結晶形Ｉ、この結晶形Ｉの製造方法、及び医薬組成物
WO2004089313A2 (en) * 2003-04-01 2004-10-21 Transform Pharmaceuticals, Inc. Novel olanzapine forms and related methods of treatment
US20030224006A1 (en) 2002-03-01 2003-12-04 Zaworotko Michael J. Multiple-component solid phases containing at least one active pharmaceutical ingredient
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
US20100311701A1 (en) * 2002-02-15 2010-12-09 Transform Pharmaceuticals, Inc Pharmaceutical Co-Crystal Compositions
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
EP2316468A1 (en) 2002-02-22 2011-05-04 Shire LLC Delivery system and methods for protecting and administering dextroamphetamine
PL196814B1 (pl) * 2002-05-17 2008-02-29 Inst Farmaceutyczny Sposób wytwarzania odmiany polimorficznej I olanzapiny i jej solwaty
SI1513846T1 (sl) * 2002-05-31 2011-11-30 Sandoz Ag Postopek za pripravo olanzapina form I
AU2003243699B2 (en) * 2002-06-21 2009-01-15 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
PL202856B1 (pl) * 2002-12-20 2009-07-31 Adamed Spo & Lstrok Ka Z Ogran Sposób otrzymywania farmaceutycznie czystej polimorficznej postaci I olanzapiny
US7323459B2 (en) 2002-12-24 2008-01-29 Teva Pharmaceutical Industries Ltd. Crystal forms, methods for their preparation and method for preparation of olanzapine
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
US20060135547A1 (en) * 2003-03-12 2006-06-22 Toth Zoltan G Stable pharmaceutical compositions of desloratadine and processes for preparation of polymorphic forms of desloratadine
WO2004080461A2 (en) * 2003-03-12 2004-09-23 TEVA Gyógyszergyár Részvénytársaság Stable pharmaceutical compositions of desloratadine
GB0314149D0 (en) * 2003-06-18 2003-07-23 Generics Uk Ltd Novel amorphous forms
GB0326148D0 (en) 2003-11-10 2003-12-17 Lilly Co Eli Morpholine derivatives
CA2546200A1 (en) * 2003-11-18 2005-06-02 3M Innovative Properties Company Olanzapine containing transdermal drug delivery compositions
DE602004014264D1 (de) * 2003-12-22 2008-07-17 Teva Pharma Verfahren zur herstellung von olanzapin
EP1709053B1 (en) 2004-01-27 2011-04-06 Synthon B.V. Stable salts of olanzapine
US20050272720A1 (en) * 2004-01-27 2005-12-08 Rolf Keltjens Process for making olanzapine Form I
ES2253091B1 (es) 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
DE112005000641T5 (de) * 2004-09-06 2007-09-06 Shasun Chemicals and Drugs Ltd., Chennai Neues Verfahren zur Herstellung einer pharmazeutisch reinen polymorphen Form I von Olanzapin
EA200701065A1 (ru) * 2004-11-16 2007-12-28 Элан Фарма Интернэшнл Лтд. Инъецируемые составы, содержащие нанодисперсный оланзапин
ATE511512T1 (de) 2005-01-05 2011-06-15 Lilly Co Eli Olanzapinpamoat-dihydrat
CZ297214B6 (cs) * 2005-02-02 2006-10-11 Zentiva, A. S. Lécivý prípravek obsahující jako úcinnou slozku olanzapin a zpusob jeho výroby
AR053562A1 (es) * 2005-03-21 2007-05-09 Reddys Lab Ltd Dr Proceso para la preparacion de la forma i cristalina de olanzapina
US20070021605A1 (en) * 2005-07-20 2007-01-25 Rolf Keltjens Process and composition for making olanzapine form i
EP1919923A1 (en) * 2005-08-17 2008-05-14 Synthon B.V. A process for making olanzapine form i
GB0522474D0 (en) * 2005-11-03 2005-12-14 Actavis Group A pharmaceutical formulation
HUP0501046A2 (en) 2005-11-11 2007-08-28 Egis Gyogyszergyar Nyilvanosan Process for the preparation of olanzapine
US8721202B2 (en) 2005-12-08 2014-05-13 Ncr Corporation Two-sided thermal print switch
US8222184B2 (en) 2006-03-07 2012-07-17 Ncr Corporation UV and thermal guard
US8367580B2 (en) 2006-03-07 2013-02-05 Ncr Corporation Dual-sided thermal security features
ES2279715B1 (es) 2005-12-26 2008-06-01 Laboratorios Lesvi, S.L. Formulacion oral de olanzapina.
US7834176B2 (en) 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
US20070293479A1 (en) * 2006-05-18 2007-12-20 Osinga Niels J Olanzapine pharmaceutical composition
CL2007002807A1 (es) * 2006-09-29 2008-04-11 Synthon Bv Composicion farmaceutica en estado solido que comprende olanzapina o una sal farmaceuticamente aceptable de la misma y lactosa anhidra; tableta farmaceutica oral; procedimiento de preparacion de dicha tableta, util en el tratamiento de la esquizofren
US7718649B1 (en) 2006-11-10 2010-05-18 Pisgah Labs, Inc. Physical states of a pharmaceutical drug substance
US8039461B1 (en) 2006-11-10 2011-10-18 Pisgah Laboratories, Inc. Physical states of a pharmaceutical drug substance
PL381564A1 (pl) 2007-01-22 2008-08-04 Koźluk Tomasz Nobilus Ent Sposób wytwarzania zasadniczo czystej odmiany polimorficznej I olanzapiny
CA2591644A1 (en) * 2007-06-14 2008-12-14 Apotex Pharmachem Inc. Novel processes to form-i of olanzapine
US9056488B2 (en) 2007-07-12 2015-06-16 Ncr Corporation Two-side thermal printer
US8883863B1 (en) 2008-04-03 2014-11-11 Pisgah Laboratories, Inc. Safety of psuedoephedrine drug products
CN101735239B (zh) * 2008-11-06 2011-08-31 齐鲁制药有限公司 一种无水奥氮平晶型ii的制备方法
EP2292624A1 (en) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Process for the purification of olanzapine
RS65091B1 (sr) 2010-08-23 2024-02-29 Alkermes Pharma Ireland Ltd Postupci za lečenje povećanja telesne težine indukovanog antipsihoticima
CN102093386B (zh) * 2011-01-05 2016-06-01 浙江华海药业股份有限公司 一种制备奥兰扎平晶型ⅱ的方法
WO2012153347A2 (en) 2011-05-04 2012-11-15 Zentiva K.S. Oral pharmaceutical composition of olanzapine form 1
CN107253993B (zh) 2012-08-21 2021-10-22 詹森药业有限公司 奥氮平的抗体及其用途
CA2882595C (en) 2012-08-21 2019-06-04 Ortho-Clinical Diagnostics, Inc. Antibodies to olanzapine haptens and use thereof
CN104736565B (zh) 2012-08-21 2019-03-12 詹森药业有限公司 利培酮半抗原的抗体及其用途
EP2919788A4 (en) 2012-11-14 2016-05-25 Univ Johns Hopkins METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA
CN103848847B (zh) * 2012-12-04 2018-02-06 广东东阳光药业有限公司 一种改进制备奥氮平及其晶型ii的方法
JP6008734B2 (ja) * 2012-12-20 2016-10-19 株式会社トクヤマ オランザピンｉｉ型結晶の製造方法
CN103145731B (zh) * 2013-02-26 2014-02-19 江苏豪森药业股份有限公司 奥氮平晶型及其制备方法和用途
WO2023139531A1 (en) 2022-01-20 2023-07-27 Teva Pharmaceuticals International Gmbh Olanzapine, compositions thereof and methods of use thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115568A (en) * 1974-11-26 1978-09-19 Lilly Industries Limited Thieno[3,2-b]-[1,5]benzodiazepines
GB1548022A (en) 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
CA1097233A (en) 1977-07-20 1981-03-10 George K. E. Gregory Packages
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
IE53696B1 (en) 1981-12-02 1989-01-18 Wyeth John & Brother Ltd Solid shaped articles
US5079018A (en) 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5039540A (en) 1989-08-14 1991-08-13 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
TW268005B (da) * 1992-05-29 1996-01-11 Lilly Industries Ltd
US5439888A (en) * 1994-03-04 1995-08-08 Eli Lilly And Company Antithrombotic agents
US5457101A (en) * 1994-06-03 1995-10-10 Eli Lilly And Company Thieno[1,5]benzoidiazepine use
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine

Also Published As

Publication number Publication date
CZ292688B6 (cs) 2003-11-12
AP9701065A0 (en) 1997-10-31
AR010448A1 (es) 2000-06-28
GB9719819D0 (en) 1997-11-19
IS1896B (is) 2003-10-20
DE69636313D1 (de) 2006-08-10
SE9703205D0 (sv) 1997-09-05
EG23659A (en) 2007-03-26
PE44897A1 (es) 1997-10-22
BG62619B1 (bg) 2000-03-31
EE03489B1 (et) 2001-08-15
CO4650278A1 (es) 1998-09-03
GB2313835B (en) 1998-09-16
CN1065536C (zh) 2001-05-09
TR199701017T1 (xx) 1998-01-21
GB2313835A (en) 1997-12-10
ZA962342B (en) 1997-09-22
MY114701A (en) 2002-12-31
DE69614426T2 (de) 2002-05-23
IL117610A0 (en) 1996-07-23
AU706471B2 (en) 1999-06-17
EE9700232A (et) 1998-04-15
CN1179160A (zh) 1998-04-15
DE69630324T2 (de) 2004-07-29
EP0733635B1 (en) 2001-08-16
FI973750A0 (fi) 1997-09-22
EP0733635A1 (en) 1996-09-25
YU17796A (sh) 1999-03-04
SI0733635T1 (en) 2002-06-30
OA10510A (en) 2002-04-24
LT97148A (en) 1998-01-26
RO118872B1 (ro) 2003-12-30
IS4564A (is) 1997-09-22
PT733635E (pt) 2001-12-28
ATA902196A (de) 2000-01-15
BG101900A (en) 1999-03-31
ATE204280T1 (de) 2001-09-15
DK108997A (da) 1997-11-12
NZ306110A (en) 1998-09-24
AT406771B (de) 2000-08-25
PT1095941E (pt) 2004-02-27
IL117610A (en) 2001-08-26
ZA962344B (en) 1997-09-22
YU49478B (sh) 2006-05-25
NO314663B1 (no) 2003-04-28
NO974365D0 (no) 1997-09-22
WO1996030375A1 (en) 1996-10-03
SI1445259T1 (sl) 2006-10-31
LT4349B (lt) 1998-05-25
PA8353701A1 (es) 1998-09-18
PT1445259E (pt) 2006-10-31
ES2159346T3 (es) 2001-10-01
CZ300097A3 (en) 1997-12-17
BR9607790A (pt) 1998-07-07
AP828A (en) 2000-04-28
EP1445259B1 (en) 2006-06-28
CA2214005C (en) 2001-07-03
LV12018B (en) 1998-09-20
SI1095941T1 (en) 2003-12-31
UA44765C2 (uk) 2002-03-15
ATE251627T1 (de) 2003-10-15
FI973750A (fi) 1997-09-22
DE69636313T2 (de) 2007-05-31
EA199700262A1 (ru) 1998-02-26
SE9703205L (sv) 1997-09-05
HU224989B1 (en) 2006-05-29
LU90096B1 (fr) 1997-07-22
MX9707183A (es) 1997-11-29
AR002719A1 (es) 1998-04-29
PL322501A1 (en) 1998-02-02
CH690579A5 (de) 2000-10-31
SI9620040A (sl) 1998-06-30
DE69614426D1 (de) 2001-09-20
ES2266719T3 (es) 2007-03-01
SI9620040B (sl) 2002-02-28
ATE331719T1 (de) 2006-07-15
SK284143B6 (sk) 2004-10-05
HUP9802824A3 (en) 2000-01-28
TW513432B (en) 2002-12-11
LV12018A (lv) 1998-04-20
HUP9802824A2 (hu) 1999-06-28
ES2208220T3 (es) 2004-06-16
SV1996000031A (es) 1998-03-27
US5736541A (en) 1998-04-07
EP1445259A1 (en) 2004-08-11
EP1095941A1 (en) 2001-05-02
CA2214005A1 (en) 1996-10-03
HK1013988A1 (en) 1999-09-17
KR100399688B1 (ko) 2004-02-18
EA000149B1 (ru) 1998-10-29
JPH11502535A (ja) 1999-03-02
DK1445259T3 (da) 2006-10-16
DE19681286T1 (de) 1998-04-02
KR19980703188A (ko) 1998-10-15
AU5427996A (en) 1996-10-16
TW442488B (en) 2001-06-23
EP1095941B1 (en) 2003-10-08
SK121897A3 (en) 1998-03-04
PL183723B1 (pl) 2002-07-31
NO974365L (no) 1997-09-22
DK0733635T3 (da) 2001-10-08
DE69630324D1 (de) 2003-11-13

Similar Documents

Publication Publication Date Title
DK1095941T3 (da) Fremgangsmåde og krystalformer for 2-methyl-thieno-benzodiazepin
NO20035726D0 (no) Benzopyran-inneholdende forbindelser og fremgangsmåte for anvendelse derav
BR9607386A (pt) Aparato e processo
NO965489D0 (no) Kontrollert denitrifikasjonsprosess og system
KR970704918A (ko) 단결정 제조장치 및 제조방법
BR9605916A (pt) Aparelho e aparelho de sintonizaçao
NO954690D0 (no) Intelligent akkompagnementsapparat og fremgangsmåte
FI965093A (fi) Laite ja menetelmä kellon säätämiseksi ja kytkemiseksi
NO975457D0 (no) Optisk apparat og fremgangsmåte
DK0863856T3 (da) Komposteringssystem og fremgangsmåde
DE69630723D1 (de) Bilderzeugungsverfahren und -gerät
DE69401016D1 (de) Biegverfahren und -gerät
DE69628873D1 (de) Ausrichtgerät und -verfahren
NO934132D0 (no) Fremgangsm}te og system for synkronisering
DE69615544D1 (de) Anzeigeverfahren und anzeigevorrichtung
DE59610014D1 (de) Schwingquarzsensor
NO993807D0 (no) Fremgangsmåte og apparatur for fremstilling av hydrolepater av krill
DE69528051D1 (de) Kristallwachstumsverfahren
NO994599L (no) Anordning og fremgangsmåte for prosodigenering av visuell syntese
DE69604455T2 (de) Einkristallziehvorrichtung
NO982396D0 (no) Bakverk og framgangsmÕte for tilvirkning av dette
FI935225A0 (fi) Menetelmä ja laite kellosignaalin symmetroimiseksi
NO960766D0 (no) Nytt protein og fremgangsmåte for fremstilling av dette
NO982362D0 (no) FremgangsmÕte og apparat for luktsetting
NO961493L (no) Stötteanordning og fremgangsmåte for tilvirkning av slike