AR002719A1 - Forma ii polimorfa 2-metil-4-(4-metil-1-piperacinil)-10h-tieno[2,3-b]-[1,5] benzodiacepina(olanzapina) y formulaciones farmaceuticas que las contienen. - Google Patents
Forma ii polimorfa 2-metil-4-(4-metil-1-piperacinil)-10h-tieno[2,3-b]-[1,5] benzodiacepina(olanzapina) y formulaciones farmaceuticas que las contienen.Info
- Publication number
- AR002719A1 AR002719A1 ARP960101876A AR10187696A AR002719A1 AR 002719 A1 AR002719 A1 AR 002719A1 AR P960101876 A ARP960101876 A AR P960101876A AR 10187696 A AR10187696 A AR 10187696A AR 002719 A1 AR002719 A1 AR 002719A1
- Authority
- AR
- Argentina
- Prior art keywords
- methyl
- olanzapine
- benzodiacepine
- piperacinyl
- theno
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
Abstract
Se trata de una nueva forma de 2-metil-4-(4-metil-1-piperacinil)-1OH-tieno [2,3-b][1,5]benzodiacepina (Olanzapina), disponible de otras formas conocidasdel mismo compuesto por difractometría (en polvo) con Rx, cuyos parámetros se detallan en las reivindicaciones y en la memoria descriptiva. Dicho compuestoútil en el tratamiento de estados psicóticos, tiene la fórmula (I). También se proponen formulaciones farmacéuticamente que incluyen dicha forma (II) comocomponente activo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40956695A | 1995-03-24 | 1995-03-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR002719A1 true AR002719A1 (es) | 1998-04-29 |
Family
ID=23621056
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP960101875A AR010448A1 (es) | 1995-03-24 | 1996-03-22 | PROCEDIMIENTO PARA OBTENER LA FORMA II POLIMORFA DE 2-METIL-4-[4-METIL-1- PIPERACINIL]-10H-TIENO-[2,3-b]-[1,5]-BENZODIACEPINA (OLANZAPINA) |
ARP960101876A AR002719A1 (es) | 1995-03-24 | 1996-03-22 | Forma ii polimorfa 2-metil-4-(4-metil-1-piperacinil)-10h-tieno[2,3-b]-[1,5] benzodiacepina(olanzapina) y formulaciones farmaceuticas que las contienen. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP960101875A AR010448A1 (es) | 1995-03-24 | 1996-03-22 | PROCEDIMIENTO PARA OBTENER LA FORMA II POLIMORFA DE 2-METIL-4-[4-METIL-1- PIPERACINIL]-10H-TIENO-[2,3-b]-[1,5]-BENZODIACEPINA (OLANZAPINA) |
Country Status (49)
Families Citing this family (82)
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CN103848847B (zh) * | 2012-12-04 | 2018-02-06 | 广东东阳光药业有限公司 | 一种改进制备奥氮平及其晶型ii的方法 |
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1996
- 1996-03-21 EG EG19960250A patent/EG23659A/xx active
- 1996-03-22 AT AT03077455T patent/ATE331719T1/de active
- 1996-03-22 PT PT03077455T patent/PT1445259E/pt unknown
- 1996-03-22 EE EE9700232A patent/EE03489B1/xx not_active IP Right Cessation
- 1996-03-22 DE DE69636313T patent/DE69636313T2/de not_active Expired - Lifetime
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- 1996-03-22 ES ES00203573T patent/ES2208220T3/es not_active Expired - Lifetime
- 1996-03-22 GB GB9719819A patent/GB2313835B/en not_active Expired - Fee Related
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- 1996-03-22 SI SI9620040A patent/SI9620040B/sl not_active IP Right Cessation
- 1996-03-22 CA CA002214005A patent/CA2214005C/en not_active Expired - Fee Related
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- 1996-03-22 SI SI9630743T patent/SI1445259T1/sl unknown
- 1996-03-22 SI SI9630345T patent/SI0733635T1/xx unknown
- 1996-03-22 PL PL96322501A patent/PL183723B1/pl not_active IP Right Cessation
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- 1996-03-22 HU HU9802824A patent/HU224989B1/hu not_active IP Right Cessation
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- 1996-03-22 CN CN96192775A patent/CN1065536C/zh not_active Expired - Lifetime
- 1996-03-22 UA UA97094737A patent/UA44765C2/uk unknown
- 1996-03-22 RO RO97-01761A patent/RO118872B1/ro unknown
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- 1996-03-22 ZA ZA9602342A patent/ZA962342B/xx unknown
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- 1996-03-22 SI SI9630636T patent/SI1095941T1/xx unknown
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- 1996-03-22 TR TR97/01017T patent/TR199701017T1/xx unknown
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- 1996-03-22 AR ARP960101876A patent/AR002719A1/es unknown
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- 1996-03-22 EP EP03077455A patent/EP1445259B1/en not_active Expired - Lifetime
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- 1996-03-22 AT AT96302000T patent/ATE204280T1/de active
- 1996-03-22 YU YU17796A patent/YU49478B/sh unknown
- 1996-03-22 SK SK1218-97A patent/SK284143B6/sk not_active IP Right Cessation
- 1996-03-22 DK DK03077455T patent/DK1445259T3/da active
- 1996-03-22 PE PE1996000203A patent/PE44897A1/es not_active IP Right Cessation
- 1996-03-22 JP JP8529532A patent/JPH11502535A/ja not_active Ceased
- 1996-03-22 WO PCT/US1996/003917 patent/WO1996030375A1/en active IP Right Grant
- 1996-03-22 IL IL11761096A patent/IL117610A/xx not_active IP Right Cessation
- 1996-03-22 ZA ZA9602344A patent/ZA962344B/xx unknown
- 1996-03-22 ES ES03077455T patent/ES2266719T3/es not_active Expired - Lifetime
- 1996-03-22 AU AU54279/96A patent/AU706471B2/en not_active Ceased
- 1996-03-22 KR KR1019970706591A patent/KR100399688B1/ko not_active IP Right Cessation
- 1996-03-22 LU LU90096A patent/LU90096B1/fr active
- 1996-03-22 CH CH02245/97A patent/CH690579A5/de not_active IP Right Cessation
- 1996-03-22 PT PT00203573T patent/PT1095941E/pt unknown
- 1996-05-09 SV SV1996000031A patent/SV1996000031A/es not_active Application Discontinuation
- 1996-07-25 US US08/686,989 patent/US5736541A/en not_active Expired - Lifetime
- 1996-10-18 PA PA19968353701A patent/PA8353701A1/es unknown
-
1997
- 1997-09-05 SE SE9703205A patent/SE9703205D0/xx not_active Application Discontinuation
- 1997-09-08 LV LVP-97-163A patent/LV12018B/en unknown
- 1997-09-16 LT LT97-148A patent/LT4349B/lt not_active IP Right Cessation
- 1997-09-22 FI FI973750A patent/FI973750A/fi unknown
- 1997-09-22 BG BG101900A patent/BG62619B1/bg unknown
- 1997-09-22 NO NO19974365A patent/NO314663B1/no not_active IP Right Cessation
- 1997-09-22 IS IS4564A patent/IS1896B/is unknown
- 1997-09-23 DK DK108997A patent/DK108997A/da not_active Application Discontinuation
- 1997-09-24 OA OA70082A patent/OA10510A/en unknown
-
1998
- 1998-12-23 HK HK98115175A patent/HK1013988A1/xx not_active IP Right Cessation
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