EE03562B1 - Novel anticonvulsant 1-ar (alk) ylimidazolin-2-ones containing a 4-position disubstituted amine radical and a process for their preparation - Google Patents

Novel anticonvulsant 1-ar (alk) ylimidazolin-2-ones containing a 4-position disubstituted amine radical and a process for their preparation

Info

Publication number
EE03562B1
EE03562B1 EE9800063A EE9800063A EE03562B1 EE 03562 B1 EE03562 B1 EE 03562B1 EE 9800063 A EE9800063 A EE 9800063A EE 9800063 A EE9800063 A EE 9800063A EE 03562 B1 EE03562 B1 EE 03562B1
Authority
EE
Estonia
Prior art keywords
ylimidazolin
alk
preparation
amine radical
ones containing
Prior art date
Application number
EE9800063A
Other languages
Estonian (et)
Other versions
EE9800063A (en
Inventor
Lankau Hans-Joachim
Menzer Manfred
Unverferth Klaus
Gewald Karl
Schfer Harry
Original Assignee
Arzneimittelwerk Dresden Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7771261&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE03562(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Arzneimittelwerk Dresden Gmbh filed Critical Arzneimittelwerk Dresden Gmbh
Publication of EE9800063A publication Critical patent/EE9800063A/en
Publication of EE03562B1 publication Critical patent/EE03562B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EE9800063A 1995-09-05 1996-07-26 Novel anticonvulsant 1-ar (alk) ylimidazolin-2-ones containing a 4-position disubstituted amine radical and a process for their preparation EE03562B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19532668A DE19532668A1 (en) 1995-09-05 1995-09-05 Novel, anticonvulsant 1-ar (alk) yl-imidazolin-2-ones which contain a disubstituted amine radical in the 4-position, and process for their preparation
PCT/EP1996/003295 WO1997009314A1 (en) 1995-09-05 1996-07-26 Novel 1-ar(alk)yl-imidazolin-2-ones containing a disubstituted amine radical in the 4th position, having an anti-convulsive effect, and process for their production

Publications (2)

Publication Number Publication Date
EE9800063A EE9800063A (en) 1998-08-17
EE03562B1 true EE03562B1 (en) 2001-12-17

Family

ID=7771261

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800063A EE03562B1 (en) 1995-09-05 1996-07-26 Novel anticonvulsant 1-ar (alk) ylimidazolin-2-ones containing a 4-position disubstituted amine radical and a process for their preparation

Country Status (32)

Country Link
EP (1) EP0863880B1 (en)
JP (1) JP4030578B2 (en)
CN (1) CN1103762C (en)
AR (1) AR003502A1 (en)
AT (1) ATE254606T1 (en)
AU (1) AU700602B2 (en)
BG (1) BG63917B1 (en)
BR (1) BR9610359A (en)
CA (1) CA2184871C (en)
CZ (1) CZ291839B6 (en)
DE (2) DE19532668A1 (en)
DK (1) DK0863880T3 (en)
EA (1) EA000535B1 (en)
EE (1) EE03562B1 (en)
ES (1) ES2208758T3 (en)
FR (1) FR13C0049I2 (en)
GE (1) GEP20022652B (en)
HK (1) HK1015776A1 (en)
HU (1) HU225956B1 (en)
IL (1) IL123333A (en)
LT (1) LT4482B (en)
LU (1) LU92263I2 (en)
NO (1) NO313829B1 (en)
NZ (1) NZ315624A (en)
PL (1) PL188287B1 (en)
PT (1) PT863880E (en)
SK (1) SK284868B6 (en)
TR (1) TR199800476T1 (en)
TW (1) TW422838B (en)
UA (1) UA46790C2 (en)
WO (1) WO1997009314A1 (en)
ZA (1) ZA967014B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19721580A1 (en) * 1997-05-23 1998-11-26 Dresden Arzneimittel Use of 1-ar (alk) yl-imidazolin-2-one for the treatment of anxiety and tension
US20050070537A1 (en) * 2002-10-10 2005-03-31 Chris Rundfeldt Use of dihydroimidazolones for the treatment of dogs
MXPA05013196A (en) * 2003-07-11 2006-03-09 Elbion Ag Method of treating or preventing central nervous system disorders with compounds having selectivity for the alpha 3 subunit of the benzodiazepine receptor.
EP2093218A1 (en) * 2008-02-22 2009-08-26 Ruggero Fariello Arylalkyl substituted imidazolidinones
JP2014521714A (en) 2011-08-12 2014-08-28 ベーリンガー インゲルハイム フェトメディカ ゲゼルシャフト ミット ベシュレンクテル ハフツング Odd isomer current (If) inhibitors for use in methods of treating and preventing feline heart failure
US9820988B2 (en) 2014-03-24 2017-11-21 Boehringer Ingelheim Vetmedica Gmbh Treatment of epileptic disorders in feline animals
IT202100000782A1 (en) 2021-01-18 2022-07-18 Procos Spa PROCESS FOR THE SYNTHESIS OF IMEPITOIN

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790380A (en) 1971-10-21 1973-04-20 American Cyanamid Co NEW (P-CHLORO) PHENYL-1 METHYL-3 IMIDAZOLIDINES, 2,4-DISUBSTITUTIONS USEFUL IN PARTICULAR AS ANTIALDOSTERONE DIURETIC AGENTS AND THEIR PREPARATION PROCESS
US4044021A (en) * 1971-10-21 1977-08-23 American Cyanamid Company Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism
US3932452A (en) * 1975-02-07 1976-01-13 Morton-Norwich Products, Inc. 1-Arylmethyl-2-imidazolidinones

Also Published As

Publication number Publication date
NO980906D0 (en) 1998-03-02
ZA967014B (en) 1997-08-18
EA000535B1 (en) 1999-10-28
HK1015776A1 (en) 1999-10-22
CN1103762C (en) 2003-03-26
CA2184871A1 (en) 1997-03-06
CA2184871C (en) 2001-08-21
TR199800476T1 (en) 1998-06-22
JPH11512101A (en) 1999-10-19
NO313829B1 (en) 2002-12-09
CN1200728A (en) 1998-12-02
DE59610827D1 (en) 2003-12-24
DE19532668A1 (en) 1997-03-06
SK284868B6 (en) 2006-01-05
PL188287B1 (en) 2005-01-31
HUP9802941A2 (en) 1999-09-28
ES2208758T3 (en) 2004-06-16
FR13C0049I1 (en) 2013-09-27
BR9610359A (en) 1999-07-06
LT98047A (en) 1998-10-26
NZ315624A (en) 1998-11-25
ATE254606T1 (en) 2003-12-15
IL123333A (en) 2001-10-31
CZ291839B6 (en) 2003-06-18
PL325413A1 (en) 1998-07-20
SK21698A3 (en) 1998-10-07
BG63917B1 (en) 2003-06-30
GEP20022652B (en) 2002-03-25
PT863880E (en) 2004-04-30
DK0863880T3 (en) 2004-03-22
BG102287A (en) 1998-09-30
AU700602B2 (en) 1999-01-07
LU92263I2 (en) 2013-10-07
LT4482B (en) 1999-03-25
AU6737596A (en) 1997-03-27
TW422838B (en) 2001-02-21
HU225956B1 (en) 2008-01-28
JP4030578B2 (en) 2008-01-09
EA199800271A1 (en) 1998-10-29
NO980906L (en) 1998-03-02
EP0863880A1 (en) 1998-09-16
EP0863880B1 (en) 2003-11-19
FR13C0049I2 (en) 2014-03-28
EE9800063A (en) 1998-08-17
IL123333A0 (en) 1998-09-24
WO1997009314A1 (en) 1997-03-13
CZ66198A3 (en) 1998-07-15
UA46790C2 (en) 2002-06-17
HUP9802941A3 (en) 1999-10-28
AR003502A1 (en) 1998-08-05
MX9801742A (en) 1998-08-30

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