EA200500487A1 - Антивирусные олигонуклеотиды, не связанные с комплементарностью последовательностей - Google Patents

Антивирусные олигонуклеотиды, не связанные с комплементарностью последовательностей

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Publication number
EA200500487A1
EA200500487A1 EA200500487A EA200500487A EA200500487A1 EA 200500487 A1 EA200500487 A1 EA 200500487A1 EA 200500487 A EA200500487 A EA 200500487A EA 200500487 A EA200500487 A EA 200500487A EA 200500487 A1 EA200500487 A1 EA 200500487A1
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Prior art keywords
sequence
animal
human
oligonucleotides
methods
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EA200500487A
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English (en)
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EA008940B1 (ru
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Эндрю Вайан
Жан-Марк Жюто
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Репликор, Инк.
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Publication of EA200500487A1 publication Critical patent/EA200500487A1/ru
Publication of EA008940B1 publication Critical patent/EA008940B1/ru

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Abstract

Описываются олигонуклеотиды со случайной последовательностью, которые обладают антивирусной активностью, а также их применение в качестве антивирусных средств. Во многих случаях олигонуклеотиды содержат более 40 нуклеотидов в длину. Описаны также способы профилактики или лечения вирусной инфекции у человека или животного и способ профилактического лечения рака, вызванного онковирусами человека или животного. Данные способы в типичном случае предусматривают введение человеку или животному, при необходимости такого лечения, фармакологически приемлемого терапевтически эффективного количества по меньшей мере одного олигонуклеотида, который функционирует способом, не связанным с комплементарностью последовательностей.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200500487A 2002-09-13 2003-09-11 Антивирусные олигонуклеотиды, не связанные с комплементарностью последовательностей EA008940B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41026402P 2002-09-13 2002-09-13
US43093402P 2002-12-05 2002-12-05
PCT/IB2003/004573 WO2004024919A1 (en) 2002-09-13 2003-09-11 Non-sequence complementary antiviral oligonucleotides

Publications (2)

Publication Number Publication Date
EA200500487A1 true EA200500487A1 (ru) 2005-10-27
EA008940B1 EA008940B1 (ru) 2007-10-26

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EA200500487A EA008940B1 (ru) 2002-09-13 2003-09-11 Антивирусные олигонуклеотиды, не связанные с комплементарностью последовательностей

Country Status (12)

Country Link
US (13) US20040162253A1 (ru)
EP (2) EP2330194A3 (ru)
JP (4) JP2005538186A (ru)
KR (1) KR101360955B1 (ru)
CN (1) CN1694959B (ru)
AU (1) AU2003267785C1 (ru)
BR (1) BR0314236A (ru)
CA (1) CA2498777C (ru)
EA (1) EA008940B1 (ru)
MX (1) MXPA05002791A (ru)
NZ (1) NZ538719A (ru)
WO (1) WO2004024919A1 (ru)

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US20040162253A1 (en) 2004-08-19
US8008269B2 (en) 2011-08-30
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US7358068B2 (en) 2008-04-15
US20040162254A1 (en) 2004-08-19
JP5514179B2 (ja) 2014-06-04
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