BR9808221A - Método de tratamento de tumor. - Google Patents

Método de tratamento de tumor.

Info

Publication number
BR9808221A
BR9808221A BR9808221-3A BR9808221A BR9808221A BR 9808221 A BR9808221 A BR 9808221A BR 9808221 A BR9808221 A BR 9808221A BR 9808221 A BR9808221 A BR 9808221A
Authority
BR
Brazil
Prior art keywords
mammal
administering
effective amount
treatment method
tumor treatment
Prior art date
Application number
BR9808221-3A
Other languages
English (en)
Inventor
Daniel L Dexter
Paul E Juniewicz
James B Rake
Daniel D Von Hoff
Original Assignee
Sanofi Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Winthrop Inc filed Critical Sanofi Winthrop Inc
Publication of BR9808221A publication Critical patent/BR9808221A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Patente de Invenção: <B> "MéTODO DE TRATAMENTO DE TUMOR". <D> De acordo com a presente invenção é provido um método de tratamento de um mamífero que tem um tumor sólido, o método compreende: a) administrar ao mamífero uma quantidade eficaz de 1,4 dióxido de 3-amino-1,2,4-benzotriazina; b) administrar ao manífero uma quantidade eficaz de paclitaxel; e c) administrar ao mamífero uma quantidade eficaz de complexo de platina. O método provê eficácia sinergética inesperada. A invenção ainda provê um kit para tratamento de um tumor em mamíferos que compreende 1,4 dióxido de 3-amino-1,2,4-benzotriazina, paclitaxel e um complexo de platina.
BR9808221-3A 1997-03-07 1998-02-17 Método de tratamento de tumor. BR9808221A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81476997A 1997-03-07 1997-03-07
PCT/US1998/003292 WO1998039009A1 (en) 1997-03-07 1998-02-17 Method of treating a tumor

Publications (1)

Publication Number Publication Date
BR9808221A true BR9808221A (pt) 2000-05-16

Family

ID=25215967

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808221-3A BR9808221A (pt) 1997-03-07 1998-02-17 Método de tratamento de tumor.

Country Status (15)

Country Link
US (2) US6063780A (pt)
EP (1) EP1014990B1 (pt)
JP (1) JP2001513110A (pt)
AT (1) ATE338553T1 (pt)
AU (1) AU6178198A (pt)
BR (1) BR9808221A (pt)
CA (1) CA2281807C (pt)
DE (1) DE69835824T2 (pt)
DK (1) DK1014990T3 (pt)
ES (1) ES2268764T3 (pt)
HR (1) HRP980095A2 (pt)
NO (1) NO324974B1 (pt)
PT (1) PT1014990E (pt)
WO (1) WO1998039009A1 (pt)
ZA (1) ZA981609B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1014990T3 (da) * 1997-03-07 2006-12-11 Sanofi Aventis Us Llc Antitumorkombination af 3 amino-1,2,4 benzotriazin-1,4 dioxid/paclitaxel/platin
DE69901725T2 (de) * 1998-10-14 2003-01-30 Debiopharm Sa Verpackung eines oxaliplatinhaltigen arzneimittels
DE19925211B4 (de) * 1999-06-01 2006-01-12 PBS Pharmaceutical Bulk Substances SA Kit zur Herstellung einer Formulierung von Paclitaxel
JP4890711B2 (ja) * 1999-08-30 2012-03-07 デビオファーム ソシエテ アノニム 非経口投与のための医薬として安定なオキザリプラチナム製剤
US7070796B1 (en) 1999-08-30 2006-07-04 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation for parenteral administration
AU2002223013A1 (en) 2000-12-12 2002-06-24 Debiopharm S.A. Pharmaceutical oxaliplatinum preparation for parenteral administration and method for obtaining same
US6476068B1 (en) 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
WO2004012746A2 (en) * 2002-08-02 2004-02-12 The Regents Of The University Of California New uses for inhibitors of inosine monophosphate dehydrogenase
WO2004103344A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7989490B2 (en) 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US20060275331A1 (en) * 2004-08-31 2006-12-07 Borek Zaludek Pharmaceutical composition, method of manufacturing and therapeutic use thereof
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
CA2624707A1 (en) * 2005-10-03 2007-04-12 Genetix Pharmaceuticals, Inc. Method for selectively depleting hypoxic cells
US20070212360A1 (en) * 2006-01-17 2007-09-13 Denko Nicholas C Modulation of mitochondrial oxygen consumption for therapeutic purposes
US8026017B2 (en) 2007-03-16 2011-09-27 The United States Of America As Represented By The Secretary Of The Army High voltage methanol fuel cell assembly using proton exchange membranes and base/acid electrolytes
CN102026634B (zh) 2008-04-10 2014-01-22 弗吉尼亚州立邦联大学 诱导肿瘤缺氧以治疗癌症
WO2014062856A1 (en) 2012-10-16 2014-04-24 Halozyme, Inc. Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods
EP4201403A1 (en) * 2021-12-21 2023-06-28 Som Innovation Biotech, S.L. Compounds tirapazamine and quazinone for use in the treatment of gm2 gangliosidoses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US5484612A (en) * 1993-09-22 1996-01-16 The Board Of Trustees Of The Leland Stanford Junior University Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
DK1014990T3 (da) * 1997-03-07 2006-12-11 Sanofi Aventis Us Llc Antitumorkombination af 3 amino-1,2,4 benzotriazin-1,4 dioxid/paclitaxel/platin

Also Published As

Publication number Publication date
HRP980095A2 (en) 1998-12-31
PT1014990E (pt) 2006-11-30
EP1014990A4 (en) 2004-03-24
DK1014990T3 (da) 2006-12-11
DE69835824D1 (de) 2006-10-19
AU6178198A (en) 1998-09-22
NO994330L (no) 1999-10-25
NO324974B1 (no) 2008-01-14
EP1014990A1 (en) 2000-07-05
JP2001513110A (ja) 2001-08-28
EP1014990B1 (en) 2006-09-06
ES2268764T3 (es) 2007-03-16
CA2281807A1 (en) 1998-09-11
DE69835824T2 (de) 2007-03-29
US6063780A (en) 2000-05-16
ATE338553T1 (de) 2006-09-15
US6319923B1 (en) 2001-11-20
WO1998039009A1 (en) 1998-09-11
ZA981609B (en) 1998-12-08
NO994330D0 (no) 1999-09-06
CA2281807C (en) 2007-10-16

Similar Documents

Publication Publication Date Title
BR9808221A (pt) Método de tratamento de tumor.
DK1068870T3 (da) Antitumormidler
ATE386808T1 (de) Arzneimittelzubereitungen für die behandlung von alpha-galactosidase a-mangel
EA199900620A1 (ru) Фталазиноны
DE69523350T2 (de) Behandlung von hyperproliferativen Gefässerkrankungen
PT880350E (pt) Tratamento de esclerose multipla
ATE258796T1 (de) Verwendung von vitamin d4-derivaten zur behandlung von hauterkrankungen
EA200101089A1 (ru) Новый способ лечения
PT902789E (pt) Derivados de androsteno
EA199900421A1 (ru) Бензонафтиридины в качестве бронхиальных терапевтических средств
EA199800717A1 (ru) Способ лечения заболеваний млекопитающих и цвиттерионная композиция
PL340679A1 (en) Application of a mixture of diole and alpha-hydroxyacid in treating
ID24184A (id) Obat untuk perawatan disfungsi ereksi
EA200000242A1 (ru) Применение фанхинона для лечения болезни альцгеймера
DE69612056D1 (de) Terpenderivate (sarcodictyine) als antikrebsmittel
ATE317263T1 (de) Diphosphonat derivate von therapeutisch wirksamen stoffen
ATE293972T1 (de) Behandlung von chronischen schmerzen
DE69814691D1 (de) Verwendung von fc101 als hemmstoff der angiogenese zur behandlung von krebs und anderen angiogenen krankheiten
EA199901061A1 (ru) Новые соли врс-пептидов с органопротективной активностью, способ их получения и их использование в терапии
DE69936779D1 (de) Verwendung von ngali nussöl zur behandlung/linderung der arthritisschmerzen und anderer ähnlichen störungen
DE69426986T2 (de) Behandlung von laminitis
RU94024337A (ru) Антиметастатическое средство
ATE271867T1 (de) Behandlung der harninkontinenz und zusammenstellung dafür
BR9807980A (pt) Uso de um composto e composto para tratar um mamìfero com disfunção cognitiva
DE69635282D1 (de) Behandlung der exzessiven aggressivität mit olanzapine

Legal Events

Date Code Title Description
TC Change of name
B25A Requested transfer of rights approved

Owner name: SANOFI-AVENTIS U.S. LLC (US)

Free format text: TRANSFERIDO DE: SANOFI-SYNTHELABO INC.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE SE OPOE AO DISPOSTO NO ART. 10 ( VIII ) DA LPI

B15G Petition not considered as such [chapter 15.7 patent gazette]

Free format text: DESCONHECIDA A PETICAO DE ALTERACAO DE SEDE, NO 020070160149/RJ DE 13/11/2007, POR AUSENCIA DE FUNDAMENTACAO LEGAL, UMA VEZ QUE O PEDIDO FOI INDEFERIDO NA RPI 1924 DE 20/11/2007.