JP2001513110A - 腫瘍治療方法 - Google Patents
腫瘍治療方法Info
- Publication number
- JP2001513110A JP2001513110A JP53855198A JP53855198A JP2001513110A JP 2001513110 A JP2001513110 A JP 2001513110A JP 53855198 A JP53855198 A JP 53855198A JP 53855198 A JP53855198 A JP 53855198A JP 2001513110 A JP2001513110 A JP 2001513110A
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- paclitaxel
- tirapazamine
- carboplatin
- mice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1. 固形腫瘍を有する哺乳動物の治療方法であって、 a) 前記動物に有効量の3−アミノ−1,2,4−ベンゾトリアジン1,4−ジ オキシドを投与し; b) 前記動物に有効量のパクリタキセルを投与し;そして c) 前記動物に有効量の白金錯体を投与する ことを含んで成る方法。 2. 前記白金錯体がオキサリプラチン、シスプラチンおよびカルボプラチンか ら成る群より選ばれる、請求項1の方法。 3. 前記白金錯体がシスプラチンである、請求項1の方法。 4. 前記白金錯体がカルボプラチンである、請求項1の方法。 5. 前記白金錯体がオキサリプラチンである、請求項1の方法。 6. 哺乳動物の腫瘍治療用キットであって、3−アミノ−1,2,4−ベンゾ トリアジン1,4−ジオキシド、パクリタキセルおよび白金錯体を含んで成るキ ット。 7. 前記白金錯体がオキサリプラチン、シスプラチンおよびカルボプラチンか ら成る群より選ばれる、請求項6のキット。 8. 前記白金錯体がシスプラチンである、請求項6のキット。 9. 前記白金錯体がカルボプラチンである、請求項6のキット。 10.前記白金錯体がオキサリプラチンである、請求項6のキット。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81476997A | 1997-03-07 | 1997-03-07 | |
US08/814,769 | 1997-03-07 | ||
PCT/US1998/003292 WO1998039009A1 (en) | 1997-03-07 | 1998-02-17 | Method of treating a tumor |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2001513110A true JP2001513110A (ja) | 2001-08-28 |
Family
ID=25215967
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP53855198A Ceased JP2001513110A (ja) | 1997-03-07 | 1998-02-17 | 腫瘍治療方法 |
Country Status (15)
Country | Link |
---|---|
US (2) | US6063780A (ja) |
EP (1) | EP1014990B1 (ja) |
JP (1) | JP2001513110A (ja) |
AT (1) | ATE338553T1 (ja) |
AU (1) | AU6178198A (ja) |
BR (1) | BR9808221A (ja) |
CA (1) | CA2281807C (ja) |
DE (1) | DE69835824T2 (ja) |
DK (1) | DK1014990T3 (ja) |
ES (1) | ES2268764T3 (ja) |
HR (1) | HRP980095A2 (ja) |
NO (1) | NO324974B1 (ja) |
PT (1) | PT1014990E (ja) |
WO (1) | WO1998039009A1 (ja) |
ZA (1) | ZA981609B (ja) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1014990B1 (en) * | 1997-03-07 | 2006-09-06 | Sanofi-Aventis U.S. LLC | Antitumor combination of 3-amino-1,2,4-benzotriazine 1,4-dioxide/paclitaxel/platinum |
PT1121117E (pt) | 1998-10-14 | 2002-10-31 | Debiopharm Sa | Acondicionamento de uma preparacao de oxaliplatina |
DE19925211B4 (de) * | 1999-06-01 | 2006-01-12 | PBS Pharmaceutical Bulk Substances SA | Kit zur Herstellung einer Formulierung von Paclitaxel |
CA2382389C (fr) * | 1999-08-30 | 2010-06-29 | Debiopharm S.A. | Preparation pharmaceutique stable d'oxaliplatine pour administration par voie parenterale |
US7070796B1 (en) | 1999-08-30 | 2006-07-04 | Debiopharm S.A. | Pharmaceutically stable oxaliplatinum preparation for parenteral administration |
EP1341555A2 (fr) | 2000-12-12 | 2003-09-10 | Debiopharm S.A. | Preparation pharmaceutique d'oxaliplatine pour administration par voie parenterale et procede d'obtention de ladite preparation |
US6476068B1 (en) | 2001-12-06 | 2002-11-05 | Pharmacia Italia, S.P.A. | Platinum derivative pharmaceutical formulations |
US20040127435A1 (en) * | 2002-08-02 | 2004-07-01 | Regents Of The University Of California | Uses for inhibitors of inosine monophosphate dehydrogenase |
EP1663153A4 (en) * | 2003-05-20 | 2011-01-05 | Aronex Pharmaceuticals Inc | COMBINATION SCHEMOTHERAPY WITH A LIPOSOMAL PLATINUM COMPLEX |
US7989490B2 (en) | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
US20060275331A1 (en) * | 2004-08-31 | 2006-12-07 | Borek Zaludek | Pharmaceutical composition, method of manufacturing and therapeutic use thereof |
JP2006248978A (ja) | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
EP1931769A2 (en) * | 2005-10-03 | 2008-06-18 | Genetix Pharmaceuticals Inc. | Method for selectively depleting hypoxic cells |
US20070212360A1 (en) * | 2006-01-17 | 2007-09-13 | Denko Nicholas C | Modulation of mitochondrial oxygen consumption for therapeutic purposes |
US8026017B2 (en) | 2007-03-16 | 2011-09-27 | The United States Of America As Represented By The Secretary Of The Army | High voltage methanol fuel cell assembly using proton exchange membranes and base/acid electrolytes |
CN102026634B (zh) | 2008-04-10 | 2014-01-22 | 弗吉尼亚州立邦联大学 | 诱导肿瘤缺氧以治疗癌症 |
WO2014062856A1 (en) | 2012-10-16 | 2014-04-24 | Halozyme, Inc. | Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods |
EP4201403A1 (en) * | 2021-12-21 | 2023-06-28 | Som Innovation Biotech, S.L. | Compounds tirapazamine and quazinone for use in the treatment of gm2 gangliosidoses |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5399363A (en) * | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
US5484612A (en) * | 1993-09-22 | 1996-01-16 | The Board Of Trustees Of The Leland Stanford Junior University | Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin |
EP1014990B1 (en) * | 1997-03-07 | 2006-09-06 | Sanofi-Aventis U.S. LLC | Antitumor combination of 3-amino-1,2,4-benzotriazine 1,4-dioxide/paclitaxel/platinum |
-
1998
- 1998-02-17 EP EP98906594A patent/EP1014990B1/en not_active Expired - Lifetime
- 1998-02-17 BR BR9808221-3A patent/BR9808221A/pt not_active Application Discontinuation
- 1998-02-17 DK DK98906594T patent/DK1014990T3/da active
- 1998-02-17 JP JP53855198A patent/JP2001513110A/ja not_active Ceased
- 1998-02-17 AU AU61781/98A patent/AU6178198A/en not_active Abandoned
- 1998-02-17 WO PCT/US1998/003292 patent/WO1998039009A1/en active IP Right Grant
- 1998-02-17 ES ES98906594T patent/ES2268764T3/es not_active Expired - Lifetime
- 1998-02-17 AT AT98906594T patent/ATE338553T1/de not_active IP Right Cessation
- 1998-02-17 DE DE69835824T patent/DE69835824T2/de not_active Expired - Fee Related
- 1998-02-17 CA CA002281807A patent/CA2281807C/en not_active Expired - Fee Related
- 1998-02-17 PT PT98906594T patent/PT1014990E/pt unknown
- 1998-02-25 HR HR08/814,769A patent/HRP980095A2/hr not_active Application Discontinuation
- 1998-02-26 ZA ZA981609A patent/ZA981609B/xx unknown
- 1998-02-27 US US09/031,692 patent/US6063780A/en not_active Expired - Fee Related
-
1999
- 1999-09-06 NO NO19994330A patent/NO324974B1/no unknown
-
2000
- 2000-02-16 US US09/505,043 patent/US6319923B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2268764T3 (es) | 2007-03-16 |
NO994330D0 (no) | 1999-09-06 |
ATE338553T1 (de) | 2006-09-15 |
CA2281807A1 (en) | 1998-09-11 |
HRP980095A2 (en) | 1998-12-31 |
EP1014990A4 (en) | 2004-03-24 |
NO994330L (no) | 1999-10-25 |
CA2281807C (en) | 2007-10-16 |
AU6178198A (en) | 1998-09-22 |
US6063780A (en) | 2000-05-16 |
US6319923B1 (en) | 2001-11-20 |
PT1014990E (pt) | 2006-11-30 |
DE69835824D1 (de) | 2006-10-19 |
WO1998039009A1 (en) | 1998-09-11 |
ZA981609B (en) | 1998-12-08 |
NO324974B1 (no) | 2008-01-14 |
DK1014990T3 (da) | 2006-12-11 |
EP1014990A1 (en) | 2000-07-05 |
EP1014990B1 (en) | 2006-09-06 |
BR9808221A (pt) | 2000-05-16 |
DE69835824T2 (de) | 2007-03-29 |
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Legal Events
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Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20050216 |
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