PT880350E - Tratamento de esclerose multipla - Google Patents

Tratamento de esclerose multipla

Info

Publication number
PT880350E
PT880350E PT96929924T PT96929924T PT880350E PT 880350 E PT880350 E PT 880350E PT 96929924 T PT96929924 T PT 96929924T PT 96929924 T PT96929924 T PT 96929924T PT 880350 E PT880350 E PT 880350E
Authority
PT
Portugal
Prior art keywords
multiple sclerosis
symptoms
sclerosis treatment
treatment
patient
Prior art date
Application number
PT96929924T
Other languages
English (en)
Inventor
Hector F Deluca
Colleen E Hayes
Margherita T Cantorna
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of PT880350E publication Critical patent/PT880350E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transplanting Machines (AREA)
  • Exposure Control For Cameras (AREA)
  • Control Of Vehicles With Linear Motors And Vehicles That Are Magnetically Levitated (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT96929924T 1996-02-13 1996-09-05 Tratamento de esclerose multipla PT880350E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/600,913 US5716946A (en) 1996-02-13 1996-02-13 Multiple sclerosis treatment

Publications (1)

Publication Number Publication Date
PT880350E true PT880350E (pt) 2002-04-29

Family

ID=24405578

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96929924T PT880350E (pt) 1996-02-13 1996-09-05 Tratamento de esclerose multipla

Country Status (12)

Country Link
US (1) US5716946A (pt)
EP (1) EP0880350B1 (pt)
JP (1) JP3701687B2 (pt)
KR (1) KR100347657B1 (pt)
AT (1) ATE209483T1 (pt)
AU (1) AU6915396A (pt)
CA (1) CA2245661C (pt)
DE (1) DE69617469T2 (pt)
DK (1) DK0880350T3 (pt)
ES (1) ES2164916T3 (pt)
PT (1) PT880350E (pt)
WO (1) WO1997029740A1 (pt)

Families Citing this family (34)

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US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6207656B1 (en) 1997-05-22 2001-03-27 Cephalon, Inc. Vitamin D analogues and their neuronal effects
ES2204165T3 (es) 1998-05-29 2004-04-16 Bone Care International, Inc. Procedimiento para la preparacion de compuestos 25-eno-vitamina d hidroxilo.
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
US6800287B2 (en) 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US6479474B2 (en) * 1999-07-08 2002-11-12 Wisconsin Alumni Research Foundation Dietary calcium as a supplement to vitamin D compound treatment of multiple sclerosis
DK1219599T3 (da) * 1999-08-27 2010-05-25 Hiroaki Takayama Vitamin-D-derivater som har substituenter i 2-alfa-position
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US7012086B1 (en) 2000-06-30 2006-03-14 The Foundation For Innovative Therapies, Inc. Treatment of retrovirus induced derangements with niacin compounds
US20050175585A1 (en) * 2001-06-11 2005-08-11 Transition Therapeutics Inc. Combination therapies using vitamin B12 and interferon for treatment of viral proliferative and inflammatory disesases
JP2005506957A (ja) * 2001-06-11 2005-03-10 トランジション・セラピューティックス・インコーポレーテッド ウイルス性、増殖性および炎症性の疾患の治療のためにビタミンｂ１２およびインターフェロンを用いた複合治療
US7658926B2 (en) * 2001-09-14 2010-02-09 Opexa Pharmaceuticals, Inc. Autologous T-cell vaccines materials and methods
NZ533327A (en) * 2001-12-04 2006-11-30 Teva Pharma Processes for the measurement of the potency of glatiramer acetate
MXPA04008068A (es) * 2002-02-20 2004-11-26 Lilly Co Eli Metodo para administrar moleculas de glp-1.
RU2327487C2 (ru) * 2002-08-08 2008-06-27 Бейлор Колледж Оф Медисин Выделение и идентификация т-клеток
US7566696B2 (en) * 2002-09-05 2009-07-28 Wisconsin Alumni Research Foundation Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis
US20040141947A1 (en) * 2002-10-16 2004-07-22 Hunter Samuel F. Method for treatment of demyelinating central nervous system disease
WO2004062620A2 (en) * 2003-01-13 2004-07-29 Cedars-Sinai Medical Center Paricalcitol as a chemotherapeutic agent
US20070037740A1 (en) * 2003-03-04 2007-02-15 Irit Pinchasi Combination therapy with glatiramer acetate and alphacalcidol for the treatment of multiple sclerosis
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
CA2580564A1 (en) * 2004-09-14 2006-03-23 Teva Pharmaceutical Industries Ltd. Methods of treating symptoms of multiple sclerosis using vitamin d and related compounds
EP1848455A1 (en) * 2005-02-14 2007-10-31 Wisconsin Alumni Research Foundation Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis
NZ572644A (en) * 2006-05-05 2012-06-29 Opexa Therapeutics T-cell vaccine
US20090221538A1 (en) * 2008-02-01 2009-09-03 Hayes Colleen E Methods of treating multiple sclerosis by administering pulse dose calcitriol
US20140296190A1 (en) * 2013-03-27 2014-10-02 Dsm Ip Assets B.V. Marketing the use of 25-hydroxyvitamin d3 to enhance cognition
CA3013554A1 (en) 2016-02-05 2017-08-10 Orionis Biosciences Nv Targeted therapeutic agents and uses thereof
WO2018144999A1 (en) 2017-02-06 2018-08-09 Orionis Biosciences, Inc. Targeted engineered interferon and uses thereof
MX2019009255A (es) 2017-02-06 2019-11-05 Orionis Biosciences Nv Proteínas quiméricas dirigidas y sus usos.

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Publication number Priority date Publication date Assignee Title
US4279826A (en) * 1980-09-22 1981-07-21 Wisconsin Alumni Research Foundation 23,25-Dihydroxyvitamin D3
US4307025A (en) * 1981-02-17 1981-12-22 Wisconsin Alumni Research Foundation 1α, 25-dihydroxy-2β-fluorovitamin D3
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US5036061A (en) * 1983-05-09 1991-07-30 Deluca Hector F Process for the preparation of 1 alpha,25-dihydroxylated vitamin D2 and related compounds
US4500460A (en) * 1983-08-18 1985-02-19 Wisconsin Alumni Research Foundation 23,23-Difluoro-25-hydroxy-vitamin D3 and process for preparing same
US4502991A (en) * 1983-08-18 1985-03-05 Wisconsin Alumni Research Foundation 23,23-Difluoro-1α,25-dihydroxy-vitamin D3
US4769181A (en) * 1983-11-07 1988-09-06 Wisconsin Alumni Research Foundation 1,25-dihydroxyvitamin D2 compounds
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4588528A (en) * 1984-05-31 1986-05-13 Wisconsin Alumni Research Foundation 1,24-dihydroxy-Δ22 -vitamin D3 and process for preparing same
US4594192A (en) * 1985-03-20 1986-06-10 Wisconsin Alumni Research Foundation 2α-fluorovitamin D3
US4619920A (en) * 1985-09-16 1986-10-28 Wisconsin Alumni Research Foundation 26,26,26,27,27-pentafluoro-1α-hydroxy-27-methoxyvitamin D3
JPS63104926A (ja) * 1986-10-21 1988-05-10 Teijin Ltd 老年性痴呆症治療又は予防剤
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
US4973584A (en) * 1989-03-09 1990-11-27 Deluca Hector F Novel 1α-hydroxyvitamin D2 epimer and derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
JP2845342B2 (ja) * 1990-04-28 1999-01-13 大正製薬株式会社 ビタミンｄ▲下３▼誘導体含有固形製剤組成物
US5260199A (en) * 1991-07-30 1993-11-09 Wisconsin Alumni Research Foundation Method of producing 1,25-dihydroxyvitamin D3 receptor protein
IL104201A0 (en) * 1991-12-26 1993-05-13 Wisconsin Alumni Res Found 26,27-dimethylene-1 alpha-25-dihydroxyvitamin d2 and its 24-epimer and pharmaceutical compositions containing them
AU666529B2 (en) * 1992-04-24 1996-02-15 Wisconsin Alumni Research Foundation Method of treating osteoporosis with 1 alpha, 24 (R)-dihydroxy-22 (E)-dehydro-vitamin D3
TW272187B (pt) * 1992-05-20 1996-03-11 Hoffmann La Roche
US5380720A (en) * 1993-05-11 1995-01-10 Wisconsin Alumni Research Foundation Iodo vitamin D3 compounds and method for preparing same
US5371249A (en) * 1993-05-11 1994-12-06 Wisconsin Alumni Research Foundation Iodo vitamin D3 compounds and method for preparing same
CA2166898C (en) * 1993-07-09 2004-09-07 Roger Bouillon Novel structural analogues of vitamin d
US5373004A (en) * 1993-11-24 1994-12-13 Wisconsin Alumni Research Foundation 26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
US5471382A (en) * 1994-01-10 1995-11-28 Informed Access Systems, Inc. Medical network management system and process

Also Published As

Publication number Publication date
JP3701687B2 (ja) 2005-10-05
US5716946A (en) 1998-02-10
JPH11510819A (ja) 1999-09-21
EP0880350A1 (en) 1998-12-02
EP0880350B1 (en) 2001-11-28
CA2245661C (en) 2004-02-03
DE69617469T2 (de) 2002-07-18
KR19990082492A (ko) 1999-11-25
DK0880350T3 (da) 2002-03-25
ES2164916T3 (es) 2002-03-01
ATE209483T1 (de) 2001-12-15
CA2245661A1 (en) 1997-08-21
WO1997029740A1 (en) 1997-08-21
AU6915396A (en) 1997-09-02
DE69617469D1 (de) 2002-01-10
KR100347657B1 (ko) 2002-11-25

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