GB8429087D0
(en)
*
|
1984-11-16 |
1984-12-27 |
Scras |
Thienopyridine derivatives
|
FR2576901B1
(fr)
*
|
1985-01-31 |
1987-03-20 |
Sanofi Sa |
Nouveaux derives de l'acide a-(oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation et leur application therapeutique
|
FR2596392B1
(fr)
*
|
1986-03-27 |
1988-08-05 |
Sanofi Sa |
Derives de l'acide a-(hydroxy-3 oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenylacetique, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
|
FR2597102B1
(fr)
*
|
1986-04-14 |
1988-08-26 |
Sanofi Sa |
Derives de l'acide a-(hydroxy-7 tetrahydro-4,5,6,7 thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation, leur application comme medicament et les compositions les renfermant
|
FR2623810B2
(fr)
*
|
1987-02-17 |
1992-01-24 |
Sanofi Sa |
Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
|
FR2612929B1
(fr)
*
|
1987-02-17 |
1990-02-09 |
Sanofi Sa |
Enantiomere dextrogyre de 1a-(tetrahydro- 4,5,6,7 thieno (3,2-c) pyridyl-5) (chloro-2 phenyl)-acetate de methyle, son procede de preparation et les compositions pharmaceutiques le renfermant
|
JPH0339159A
(ja)
*
|
1989-07-07 |
1991-02-20 |
Toichi Chikuma |
健康用具
|
FR2652575B1
(fr)
*
|
1989-09-29 |
1992-01-24 |
Sanofi Sa |
Procede de preparation d'acides alpha-bromo phenylacetiques.
|
US5189170A
(en)
*
|
1989-09-29 |
1993-02-23 |
Sanofi |
Process for the preparation of phenylacetic derivatives of thieno-pyridines
|
JPH03242154A
(ja)
*
|
1990-02-17 |
1991-10-29 |
Toichi Chikuma |
健康用具
|
FR2664596B1
(fr)
*
|
1990-07-10 |
1994-06-10 |
Sanofi Sa |
Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese.
|
FR2672801B1
(fr)
*
|
1991-02-14 |
1995-03-03 |
Sanofi Sa |
Utilisation de derives de tetrahydrothienopyridine comme inhibiteurs de l'angiogenese.
|
FI101150B
(fi)
*
|
1991-09-09 |
1998-04-30 |
Sankyo Co |
Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
|
NZ334389A
(en)
*
|
1996-08-28 |
2001-05-25 |
Ube Industries |
Cyclic amine derivatives
|
HU222283B1
(hu)
*
|
1997-05-13 |
2003-05-28 |
Sanofi-Synthelabo |
Eljárás tieno[3,2-c]piridin-származékok előállítására
|
HU225503B1
(en)
|
1997-05-13 |
2007-01-29 |
Sanofi Aventis |
Novel 2-(2-halophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides and process for producing them
|
HU225504B1
(en)
*
|
1997-05-13 |
2007-01-29 |
Sanofi Aventis |
Novel halophenyl-(2-(2-thienyl)-ethylamino)-acetonitriles and process for producing them
|
FR2769313B1
(fr)
*
|
1997-10-06 |
2000-04-21 |
Sanofi Sa |
Derives d'esters hydroxyacetiques, leur procede de preparation et leur utilisation comme intermediaires de synthese
|
KR100567950B1
(ko)
|
1998-02-27 |
2006-04-05 |
상꾜 가부시키가이샤 |
환상 아미노화합물
|
PT1087775E
(pt)
|
1998-06-17 |
2005-11-30 |
Bristol Myers Squibb Co |
Prevencao de enfarte cerebral por administracao de uma combinacao de farmacos antiplaquetarios bloqueadores de receptores de adp e anti-hipertensivos
|
HU226421B1
(en)
*
|
1998-11-09 |
2008-12-29 |
Sanofi Aventis |
Process for racemizing optically active 2-(2-chlorophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides
|
RU2270695C2
(ru)
|
1999-03-17 |
2006-02-27 |
Дайити Фармасьютикал Ко., Лтд. |
Фармацевтическая композиция
|
EP1350511B1
(de)
*
|
2000-12-25 |
2008-09-10 |
Daiichi Sankyo Company, Limited |
Aspirin enthaltende medizinische zusammensetzungen
|
IN191030B
(de)
|
2001-01-24 |
2003-09-13 |
Cadila Healthcare Ltd |
|
MXPA03006133A
(es)
*
|
2001-01-24 |
2004-05-04 |
Cadila Healthcare Ltd |
Proceso para preparar clopidogrel.
|
CA2352520C
(en)
*
|
2001-07-06 |
2007-10-02 |
Brantford Chemicals Inc. |
Process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives
|
US6495691B1
(en)
|
2001-07-06 |
2002-12-17 |
Brantford Chemicals Inc. |
Process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives
|
US6767913B2
(en)
|
2001-12-18 |
2004-07-27 |
Teva Pharmaceutical Industries Ltd. |
Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms
|
US7074928B2
(en)
|
2002-01-11 |
2006-07-11 |
Teva Pharmaceutical Industries, Ltd. |
Polymorphs of clopidogrel hydrogensulfate
|
HUP0200438A3
(en)
*
|
2002-02-06 |
2003-10-28 |
Egis Gyogyszergyar Nyilvanosan |
Novel clopidogrel hydrochloride polymorphs, process for the preparation thereof, their use and pharmaceutical compositions containing them
|
ITMI20020933A1
(it)
*
|
2002-05-03 |
2003-11-03 |
Danimite Dipharma S P A |
Procedimento per la sintesi di clopidogrel
|
US6800759B2
(en)
*
|
2002-08-02 |
2004-10-05 |
Teva Pharmaceutical Industries Ltd. |
Racemization and enantiomer separation of clopidogrel
|
IL166593A0
(en)
|
2002-08-02 |
2006-01-15 |
|
Racemization and enantiomer separation of clopidogrel
|
US20040067995A1
(en)
*
|
2002-10-02 |
2004-04-08 |
Wong Pancras C. |
Novel combination of a factor Xa inhibitor and clopidogrel
|
US6812363B2
(en)
*
|
2002-10-15 |
2004-11-02 |
Usv Limited |
Racemization of optically active 2-substituted phenyl glycine esters
|
ITMI20022228A1
(it)
*
|
2002-10-21 |
2004-04-22 |
Dinamite Dipharma S P A |
Sali di clopidogrel con acidi alchil-solforici.
|
EP1606231A1
(de)
*
|
2003-02-03 |
2005-12-21 |
Nadkarni, Sunil Sadanand |
Verfahren zur herstellung von clopidogrel, seine salze und pharmazeutische zusammensetzungen
|
DE10305984A1
(de)
*
|
2003-02-13 |
2004-09-02 |
Helm Ag |
Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
|
EP1603920A1
(de)
|
2003-03-12 |
2005-12-14 |
Cadila Healthcare Ltd. |
Polymorphe und amorphe form (s)-(+)-clopidogrel-bisulfat
|
EP1618111B1
(de)
|
2003-04-25 |
2014-12-24 |
Cadila Healthcare Limited |
Salze von clopidogrel und herstellungsverfahren
|
DE10337773A1
(de)
*
|
2003-08-13 |
2005-03-24 |
Krka Tovarna Zdravil, D.D. |
Kristallisation von festen Formen von Clopidogrel-Additionssalzen
|
GB0321256D0
(en)
|
2003-09-11 |
2003-10-08 |
Generics Uk Ltd |
Novel crystalline compounds
|
US8907090B2
(en)
|
2003-11-03 |
2014-12-09 |
Cadila Healthcare Limited |
Processes for preparing different forms of (S)-(+)-Clopidogrel bisulfate
|
CA2454015C
(en)
*
|
2003-12-23 |
2009-11-24 |
Brantford Chemicals Inc. |
A process for the preparation of tetrahydrothieno [3,2-c] pyridine derivatives
|
CA2457459A1
(en)
*
|
2004-02-11 |
2005-08-11 |
Brantford Chemicals Inc. |
Resolution of racemates of methyl alpha-5-(4,5,6,7-tetrahydro(3,2-c)thienopyridyl)-(2-chlorophenyl) acetate
|
EP1750701A1
(de)
*
|
2004-06-01 |
2007-02-14 |
IVAX Pharmaceuticals s.r.o. |
Amorphes clopidogrel-hydrochlorid und seine antithrombotische anwendung
|
AR050631A1
(es)
*
|
2004-09-09 |
2006-11-08 |
Novartis Ag |
Combinacion de compuestos organicos
|
US20060154957A1
(en)
*
|
2004-09-21 |
2006-07-13 |
Nina Finkelstein |
Crystalline clopidogrel hydrobromide and processes for preparation thereof
|
EP1851231A2
(de)
*
|
2005-02-24 |
2007-11-07 |
Teva Pharmaceutical Industries Ltd |
Zur pharmazeutischen formulierung geeignete clopidogrel-basis und deren herstellung
|
CZ299213B6
(cs)
|
2005-03-08 |
2008-05-21 |
Zentiva, A. S |
Zpusob racemizace R(-) izomeru methylesteru kyseliny (2-chlorfenyl)-6,7-dihydro-thieno[3,2-c]pyridin-5(4H)-octové
|
WO2006130852A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Dr. Reddy's Laboratories Ltd. |
Recovery of clopidogrel bisulfate
|
WO2007032023A2
(en)
|
2005-07-12 |
2007-03-22 |
Rpg Life Sciences Limited |
A process for preparation of methyl-(+)-(s)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4h)-acetic acid methyl ester or salts thereof having higher chiral purity and products thereof
|
WO2007029096A2
(en)
*
|
2005-09-05 |
2007-03-15 |
Ranbaxy Laboratories Limited |
Novel polymorphic forms of clopidogrel hydrochloride
|
EP1934229B1
(de)
*
|
2005-09-05 |
2012-09-26 |
Cadila Healthcare Limited |
Verfahren zur herstellung verschiedener formen von (s)-(+)-clopidogrel-besylat
|
WO2007029080A1
(en)
*
|
2005-09-05 |
2007-03-15 |
Ranbaxy Laboratories Limited |
Preparation of form i of clopidogrel hydrochloride
|
CN100390180C
(zh)
*
|
2005-12-15 |
2008-05-28 |
上海应用技术学院 |
氯吡格雷及其盐的制备方法
|
KR101235117B1
(ko)
*
|
2005-12-26 |
2013-02-20 |
에스케이케미칼주식회사 |
광학분리에 의한 (s)-(+)-클로피도그렐의 제조방법
|
KR100742134B1
(ko)
*
|
2006-02-07 |
2007-07-24 |
경동제약 주식회사 |
결정성S-(+)-메틸-2-(2-클로로페닐)-2-(6,7-디히드로티에노[3,2-c]피리딘-5(4H)-일)아세테이트·캄실레이트를 포함하는약학적 조성물
|
JP5844028B2
(ja)
|
2006-04-04 |
2016-01-13 |
ケージー アクキュイシチオン エルエルシー |
抗血小板薬及び酸阻害薬を含む経口剤形
|
RU2008146758A
(ru)
*
|
2006-04-27 |
2010-06-10 |
Инд-Свифт Лэборетриз Лимитед (In) |
Способ получения полиморфных форм клопидогрела гидросульфата
|
EP2064217B1
(de)
*
|
2006-09-04 |
2011-01-19 |
Ranbaxy Laboratories Limited |
Verbessertes verfahren zur herstellung von clopidogrel und pharmazeutisch unbedenklichen salzen davon
|
EP1900358A1
(de)
|
2006-09-16 |
2008-03-19 |
Cimex Pharma AG |
Clopidogrel enthaltende Arzneiformulierungen
|
WO2008060934A2
(en)
*
|
2006-11-14 |
2008-05-22 |
Acusphere, Inc. |
Formulations of tetrahydropyridine antiplatelet agents for parenteral or oral administration
|
EP1980563A1
(de)
|
2007-04-09 |
2008-10-15 |
BATTULA, Srinivasa Reddy |
Verfahren zur Herstellung von Methyl (+)-(S)-Alpha-(O-Chlorophenyl)-6,7-Dihydrothieno-[3,2-C]pyridine-5(4H) Acetat
|
KR20090086903A
(ko)
*
|
2007-04-18 |
2009-08-14 |
테바 파마슈티컬 인더스트리즈 리미티드 |
개선된 클로피도그렐의 제조 방법
|
KR20150041173A
(ko)
|
2007-04-27 |
2015-04-15 |
사이덱스 파마슈티칼스, 인크. |
클로피도그렐 및 설포알킬 에테르 사이클로덱스트린을 함유하는 제형 및 사용 방법
|
US7985859B2
(en)
*
|
2007-05-30 |
2011-07-26 |
Wockhardt Ltd. |
Processes for the preparation of clopidogrel
|
WO2009080469A1
(en)
*
|
2007-12-24 |
2009-07-02 |
Sandoz Ag |
Process for the preparation of clopidogrel bisulphate form i
|
ATE530172T1
(de)
*
|
2008-02-26 |
2011-11-15 |
Lesvi Laboratorios Sl |
Pharmazeutische formulierungen mit clopidogrel
|
EP2258364A4
(de)
|
2008-04-01 |
2012-07-25 |
Astellas Pharma Inc |
Prophylaktikum und/oder heilmittel für gefässkrankheiten
|
EP2107061A1
(de)
|
2008-04-02 |
2009-10-07 |
Krka Tovarna Zdravil, D.D., Novo Mesto |
Herstellungsverfahren für optisch angereichertes Clopidogrel
|
US20090264460A1
(en)
*
|
2008-04-21 |
2009-10-22 |
Mamta Mishra |
Clopidogrel pharmaceutical formulations
|
US20130303477A1
(en)
*
|
2008-05-13 |
2013-11-14 |
The Medicines Company |
Maintenance of Platelet Inhibition During Antiplatelet Therapy
|
US9427448B2
(en)
|
2009-11-11 |
2016-08-30 |
The Medicines Company |
Methods of treating, reducing the incidence of, and/or preventing ischemic events
|
WO2009140092A1
(en)
|
2008-05-13 |
2009-11-19 |
The Medicines Company |
Maintenance of platelet inhibition during antiplatelet therapy
|
US8759316B2
(en)
*
|
2008-05-13 |
2014-06-24 |
The Medicines Company |
Maintenance of platelet inhibition during antiplatelet therapy
|
US20120141468A1
(en)
|
2008-05-13 |
2012-06-07 |
Lisa Ruderman Chen |
Maintenance of platelet inhibition during antiplatelet therapy
|
KR100990949B1
(ko)
*
|
2008-06-09 |
2010-10-29 |
엔자이텍 주식회사 |
클로피도그렐 및 그의 유도체의 제조방법
|
US8299097B2
(en)
*
|
2008-09-12 |
2012-10-30 |
The Brigham And Women's Hospital, Inc. |
Methods for treating inflammatory disorders
|
WO2010046476A1
(en)
*
|
2008-10-24 |
2010-04-29 |
Sandoz Ag |
A process for the preparation of s-clopidogrel
|
US8563690B2
(en)
*
|
2008-11-03 |
2013-10-22 |
The Board Of Trustees Of The University Of Illinois |
Modulation of platelet aggregation
|
CN101402641B
(zh)
*
|
2008-11-20 |
2011-05-04 |
天津药物研究院 |
含噻吩并吡啶的肟类衍生物、其制备方法和用途
|
AU2010233089B2
(en)
|
2009-04-10 |
2016-05-26 |
Tufts Medical Center, Inc. |
Par-1 activation by metalloproteinase-1 (MMP-1)
|
KR101743591B1
(ko)
|
2009-05-13 |
2017-06-20 |
사이덱스 파마슈티칼스, 인크. |
프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법
|
KR20120050437A
(ko)
|
2009-06-25 |
2012-05-18 |
테트라, 시아 |
신규한 아세틸살리실산 염들
|
CN101585842B
(zh)
*
|
2009-07-13 |
2011-07-20 |
北京赛科药业有限责任公司 |
氯吡格雷中杂质b的研究及控制方法
|
US10376532B2
(en)
|
2009-11-11 |
2019-08-13 |
Chiesi Farmaceutici, S.P.A. |
Methods of treating, reducing the incidence of, and/or preventing ischemic events
|
EA028885B1
(ru)
|
2009-11-11 |
2018-01-31 |
Чиези Фармачеутичи С.П.А. |
Способы лечения или предотвращения тромбоза стента и инфаркта миокарда (варианты)
|
WO2011101865A2
(en)
|
2010-02-19 |
2011-08-25 |
Cadila Healthcare Limited |
Stable pharmaceutical compositions of clopidogrel for parenteral delivery
|
CN102212069A
(zh)
*
|
2010-04-06 |
2011-10-12 |
刘桂坤 |
环烷衍生物及其制备方法和在心脑血管病药物上的应用
|
CN101812071A
(zh)
*
|
2010-05-10 |
2010-08-25 |
杭州和素化学技术有限公司 |
硫酸氢氯吡格雷中间体拆分后的母液处理方法
|
CN102241690B
(zh)
|
2010-05-13 |
2015-08-12 |
天津药物研究院 |
一类含腈基的噻吩并吡啶酯类衍生物、其制备方法和用途
|
CN101863901B
(zh)
*
|
2010-06-29 |
2012-12-05 |
天津药物研究院 |
2-(取代苯基)-2-(4,5,6,7-四氢噻吩并[3,2-c]吡啶-5(4H)-基)-N-取代-乙酰胺、其制备方法和用途
|
WO2012007019A1
(en)
|
2010-07-13 |
2012-01-19 |
Pharmathen S.A. |
Process for the preparation of clopidogrel and salts thereof
|
BR112013004165B1
(pt)
|
2010-08-26 |
2021-07-20 |
Ipca Laboratories Limited |
Composição para o tratamento ou profilaxia da trombose ou embolia
|
CN101974015B
(zh)
*
|
2010-10-11 |
2012-05-09 |
天津药物研究院 |
酯类化合物、其制备方法和用途
|
CN101962388B
(zh)
*
|
2010-10-14 |
2012-12-19 |
天津药物研究院 |
乙酰胺衍生物及其制备方法和用途
|
CN101974016A
(zh)
*
|
2010-10-14 |
2011-02-16 |
天津药物研究院 |
酰胺类化合物及其制备方法和用途
|
JP5856177B2
(ja)
|
2010-10-18 |
2016-02-09 |
セレニス セラピューティクス ホールディング エスアー |
コレステロールモビリゼーションに有用な化合物、組成物及び方法
|
WO2012123958A1
(en)
|
2011-02-14 |
2012-09-20 |
Cadila Healthcare Limited |
Highly pure salts of clopidogrel free of genotoxic impurities
|
EP2675813A4
(de)
|
2011-06-27 |
2014-04-30 |
Ipca Lab Ltd |
Antithromboseverbindungen
|
WO2013033178A1
(en)
|
2011-08-30 |
2013-03-07 |
University Of Utah Research Foundation |
Methods and compositions for treating nephrogenic diabetes insipidus
|
RU2014127884A
(ru)
|
2011-12-09 |
2016-02-10 |
Вокхардт Лимитед |
Способы лечения сердечно-сосудистого нарушения
|
CN103665042B
(zh)
*
|
2012-09-21 |
2016-03-16 |
北京普禄德医药科技有限公司 |
光学活性的2-羟基四氢噻吩并吡啶衍生物及其制备方法和用途
|
CN102993210A
(zh)
*
|
2012-12-19 |
2013-03-27 |
苏春华 |
一种吡啶并噻吩的新化合物
|
WO2014118802A1
(en)
|
2013-01-31 |
2014-08-07 |
Pharmazell Gmbh |
An improved process for the preparation of clopidogrel bisulfate form-i
|
CN104447867B
(zh)
*
|
2013-09-17 |
2017-12-26 |
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(hu)
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|
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|
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*
|
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