DZ2289A1 - Dérivés 6,6-ou 6,7 bicycliques à noyau pyrido ou pyrimido substitués. - Google Patents

Dérivés 6,6-ou 6,7 bicycliques à noyau pyrido ou pyrimido substitués.

Info

Publication number
DZ2289A1
DZ2289A1 DZ970139A DZ970139A DZ2289A1 DZ 2289 A1 DZ2289 A1 DZ 2289A1 DZ 970139 A DZ970139 A DZ 970139A DZ 970139 A DZ970139 A DZ 970139A DZ 2289 A1 DZ2289 A1 DZ 2289A1
Authority
DZ
Algeria
Prior art keywords
bicyclic
derivatives
substituted pyrido
pyrimido ring
pyrimido
Prior art date
Application number
DZ970139A
Other languages
English (en)
Inventor
Liang Chen Yuhpyng
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DZ2289A1 publication Critical patent/DZ2289A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DZ970139A 1996-08-06 1997-08-06 Dérivés 6,6-ou 6,7 bicycliques à noyau pyrido ou pyrimido substitués. DZ2289A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2345396P 1996-08-06 1996-08-06

Publications (1)

Publication Number Publication Date
DZ2289A1 true DZ2289A1 (fr) 2002-12-25

Family

ID=21815208

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ970139A DZ2289A1 (fr) 1996-08-06 1997-08-06 Dérivés 6,6-ou 6,7 bicycliques à noyau pyrido ou pyrimido substitués.

Country Status (41)

Country Link
US (1) US6492520B1 (fr)
EP (1) EP0920429B1 (fr)
JP (1) JP3345021B2 (fr)
KR (1) KR20000029843A (fr)
CN (1) CN1093130C (fr)
AP (1) AP1096A (fr)
AR (1) AR008829A1 (fr)
AT (1) ATE232863T1 (fr)
AU (1) AU709203B2 (fr)
BG (1) BG103143A (fr)
BR (1) BR9710808A (fr)
CA (1) CA2262692C (fr)
CO (1) CO4900060A1 (fr)
CZ (1) CZ292806B6 (fr)
DE (1) DE69719193T2 (fr)
DK (1) DK0920429T3 (fr)
DZ (1) DZ2289A1 (fr)
EA (1) EA003188B1 (fr)
ES (1) ES2191183T3 (fr)
GT (1) GT199700089A (fr)
HK (1) HK1021734A1 (fr)
HR (1) HRP970432B1 (fr)
ID (1) ID17980A (fr)
IL (1) IL128188A0 (fr)
IS (1) IS4948A (fr)
MA (1) MA24296A1 (fr)
NO (1) NO313293B1 (fr)
NZ (1) NZ333727A (fr)
OA (1) OA10970A (fr)
PA (1) PA8435201A1 (fr)
PE (1) PE97098A1 (fr)
PL (1) PL331602A1 (fr)
SA (1) SA97180334A (fr)
SK (1) SK14099A3 (fr)
TN (1) TNSN97135A1 (fr)
TR (1) TR199900228T2 (fr)
TW (1) TW550265B (fr)
UY (1) UY24655A1 (fr)
WO (1) WO1998005661A1 (fr)
YU (1) YU5399A (fr)
ZA (1) ZA976954B (fr)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
PT1129091E (pt) 1998-11-12 2003-02-28 Neurocrine Biosciences Inc Antagonistas de receptor de crf e metodos relacionados
CN1178941C (zh) 1998-11-12 2004-12-08 纽罗克里恩生物科学有限公司 Crf受体拮抗剂以及与其有关的方法
US6432989B1 (en) * 1999-08-27 2002-08-13 Pfizer Inc Use of CRF antagonists to treat circadian rhythm disorders
IL139197A0 (en) * 1999-10-29 2001-11-25 Pfizer Prod Inc Use of corticotropin releasing factor antagonists and related compositions
KR20030016222A (ko) * 2000-02-14 2003-02-26 니뽄 다바코 산교 가부시키가이샤 수술후 스트레스 예방ㆍ치료제
AU2001234180A1 (en) * 2000-02-25 2001-09-03 Japan Tobacco Inc. Benzamide derivative and use thereof
US7235551B2 (en) * 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
AR030053A1 (es) * 2000-03-02 2003-08-13 Smithkline Beecham Corp 1h-pirimido [4,5-d] pirimidin-2-onas y sales, composiciones farmaceuticas, uso para la fabricacion de un medicamento y procedimiento para producirlas
GB0011964D0 (en) 2000-05-18 2000-07-05 Suyal N Thick glass films with controlled refractive indices and their applications
JP4524072B2 (ja) 2000-10-23 2010-08-11 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 新規化合物
GB0117396D0 (en) 2001-07-17 2001-09-05 Glaxo Group Ltd Chemical compounds
JP2005504807A (ja) 2001-09-26 2005-02-17 バイエル・フアーマシユーチカルズ・コーポレーシヨン 抗糖尿病薬としての1,8−ナフチリジン誘導体
CA2482022A1 (fr) 2002-04-19 2003-10-30 Smithkline Beecham Corporation Nouveaux composes
FR2846657B1 (fr) * 2002-11-05 2004-12-24 Servier Lab Nouveaux composes pyridopyrimidinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US7109337B2 (en) 2002-12-20 2006-09-19 Pfizer Inc Pyrimidine derivatives for the treatment of abnormal cell growth
PT1625121E (pt) 2002-12-20 2010-03-11 Pfizer Prod Inc Derivados de piridina para o tratamento de crescimento celular anormal
GB0308208D0 (en) 2003-04-09 2003-05-14 Glaxo Group Ltd Chemical compounds
US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
US7618975B2 (en) 2003-07-03 2009-11-17 Myriad Pharmaceuticals, Inc. 4-arylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
US20050085479A1 (en) * 2003-08-27 2005-04-21 Pharmacia Corporation Mediated central nervous system compositions of a cyclooxygenase-2 selective inhibitor and a corticotropin releasing factor antagonist for the treatment of ischemic disorders or injury
EP2522670A1 (fr) * 2004-04-07 2012-11-14 Takeda Pharmaceutical Company Limited Antagonistes hétérocycliques des récépteurs du CRF
BRPI0511132A (pt) 2004-05-14 2007-11-27 Pfizer Prod Inc derivados de pirimidina e composição farmacêutica compreendendo os mesmos
MXPA06013164A (es) 2004-05-14 2007-02-13 Pfizer Prod Inc Derivados de pirimidina para el tratamiento de crecimiento de celulas anormal.
BRPI0510963A (pt) 2004-05-14 2007-11-20 Pfizer Prod Inc derivados pirimidina para o tratamento do crescimento anormal de células
CA2592900A1 (fr) 2005-01-03 2006-07-13 Myriad Genetics Inc. Composes et utilisation therapeutique associee
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
UY29439A1 (es) * 2005-03-25 2006-10-02 Glaxo Group Ltd Nuevos compuestos
AR053346A1 (es) 2005-03-25 2007-05-02 Glaxo Group Ltd Compuesto derivado de 8h -pirido (2,3-d) pirimidin -7 ona 2,4,8- trisustituida composicion farmaceutica y uso para preparar una composicion para tratamiento y profilxis de una enfermedad mediada por la quinasa csbp/ rk/p38
WO2006110298A2 (fr) * 2005-03-25 2006-10-19 Glaxo Group Limited Nouveaux composes
AU2006229995A1 (en) * 2005-03-25 2006-10-05 Glaxo Group Limited Process for preparing pyrido(2,3-d)pyrimidin-7-one and 3,4-dihydropyrimido(4,5-d)pyrimidin-2(1H)-one derivatives
RU2419610C2 (ru) 2005-05-26 2011-05-27 Ньюрон Системз, Инк. Композиции и способы лечения заболевания сетчатки
EP2345652A1 (fr) 2005-12-21 2011-07-20 Abbott Laboratories Composées antivirales
WO2007081517A2 (fr) 2005-12-21 2007-07-19 Abbott Laboratories Composes anti-viraux
DE602006015861D1 (de) 2005-12-21 2010-09-09 Abbott Lab Antivirale verbindungen
KR20080080395A (ko) 2005-12-21 2008-09-03 아보트 러보러터리즈 항바이러스 화합물
EP2094276A4 (fr) 2006-12-20 2011-01-05 Abbott Lab Composés antiviraux
NZ612380A (en) 2008-12-09 2015-01-30 Gilead Sciences Inc Modulators of toll-like receptors
US8551996B2 (en) * 2009-02-20 2013-10-08 Emory University Compounds, compositions, methods of synthesis, and methods of treatment
PT2477987T (pt) 2009-09-14 2018-03-13 Gilead Sciences Inc Moduladores de recetores do tipo toll
JP5885670B2 (ja) 2009-12-11 2016-03-15 アルデイラ セラピューティクス, インコーポレイテッド 黄斑変性の処置のための組成物および方法
WO2012088266A2 (fr) 2010-12-22 2012-06-28 Incyte Corporation Imidazopyridazines et benzimidazoles substitués en tant qu'inhibiteurs de fgfr3
WO2014007951A2 (fr) 2012-06-13 2014-01-09 Incyte Corporation Composés tricycliques substitués utilisés comme inhibiteurs de fgfr
WO2014026125A1 (fr) 2012-08-10 2014-02-13 Incyte Corporation Dérivés de pyrazine en tant qu'inhibiteurs de fgfr
US9266892B2 (en) 2012-12-19 2016-02-23 Incyte Holdings Corporation Fused pyrazoles as FGFR inhibitors
KR102435676B1 (ko) 2013-01-23 2022-08-24 알데이라 테라퓨틱스, 아이엔씨. 독성 알데히드 관련된 질병 및 치료
DK2986610T5 (en) 2013-04-19 2018-12-10 Incyte Holdings Corp BICYCLIC HETEROCYCLES AS FGFR INHIBITORS
US10882868B2 (en) 2014-05-15 2021-01-05 Hoffmann-La Roche Inc. Compounds for treating spinal muscular atrophy
PT3143025T (pt) * 2014-05-15 2019-12-03 Hoffmann La Roche Compostos para tratamento da atrofia muscular espinhal
CN113577081A (zh) 2014-07-11 2021-11-02 吉利德科学公司 用于治疗hiv的toll样受体调节剂
CN110305133A (zh) 2014-09-16 2019-10-08 吉利德科学公司 Toll样受体调节剂的固体形式
PT3194402T (pt) 2014-09-16 2019-02-11 Gilead Sciences Inc Métodos de preparação de moduladores dos recetores tipo toll
US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
NZ773116A (en) 2015-02-20 2024-05-31 Incyte Holdings Corp Bicyclic heterocycles as fgfr inhibitors
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
US9580423B2 (en) 2015-02-20 2017-02-28 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
EP3317278B1 (fr) 2015-07-01 2021-04-14 Crinetics Pharmaceuticals, Inc. Modulateurs de somatostatine et leurs utilisations
CN118724806A (zh) 2015-08-21 2024-10-01 奥尔德拉医疗公司 氘化化合物和其用途
UA124879C2 (uk) 2016-02-12 2021-12-08 Сайтокінетікс, Інкорпорейтед Похідні тетрагідроізохіноліну
AR111960A1 (es) 2017-05-26 2019-09-04 Incyte Corp Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
WO2019023278A1 (fr) 2017-07-25 2019-01-31 Crinetics Pharmaceuticals, Inc. Modulateurs de la somatostatine et utilisations de ces derniers
US11040039B2 (en) 2017-10-10 2021-06-22 Aldeyra Therapeutics, Inc. Treatment of inflammatory disorders
SG11202010636VA (en) 2018-05-04 2020-11-27 Incyte Corp Solid forms of an fgfr inhibitor and processes for preparing the same
BR112020022373A2 (pt) 2018-05-04 2021-02-02 Incyte Corporation sais de um inibidor de fgfr
JP2021533154A (ja) 2018-08-06 2021-12-02 アルデイラ セラピューティクス, インコーポレイテッド 多形化合物およびその使用
CN113056353B (zh) 2018-09-25 2022-11-01 奥尔德拉医疗公司 用于治疗干眼病的调配物
US11628162B2 (en) 2019-03-08 2023-04-18 Incyte Corporation Methods of treating cancer with an FGFR inhibitor
WO2020198064A1 (fr) 2019-03-26 2020-10-01 Aldeyra Therapeutics, Inc. Formulations ophtalmiques et leurs utilisations
CA3137301A1 (fr) 2019-05-02 2020-11-05 Aldeyra Therapeutics, Inc. Composes polymorphes et leurs utilisations
WO2020223717A1 (fr) 2019-05-02 2020-11-05 Aldeyra Therapeutics, Inc. Procédé de préparation d'un piégeur d'aldéhyde et d'intermédiaires
WO2021007269A1 (fr) 2019-07-09 2021-01-14 Incyte Corporation Hétérocycles bicycliques en tant qu'inhibiteurs de fgfr
WO2021067374A1 (fr) 2019-10-01 2021-04-08 Incyte Corporation Hétérocycles bicycliques en tant qu'inhibiteurs de fgfr
BR112022007163A2 (pt) 2019-10-14 2022-08-23 Incyte Corp Heterociclos bicíclicos como inibidores de fgfr
US11566028B2 (en) 2019-10-16 2023-01-31 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
JP2023505258A (ja) 2019-12-04 2023-02-08 インサイト・コーポレイション Fgfr阻害剤としての三環式複素環
US11407750B2 (en) 2019-12-04 2022-08-09 Incyte Corporation Derivatives of an FGFR inhibitor
US12012409B2 (en) 2020-01-15 2024-06-18 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
WO2021231792A1 (fr) 2020-05-13 2021-11-18 Aldeyra Therapeutics, Inc. Formulations pharmaceutiques et leurs utilisations
WO2022221170A1 (fr) 2021-04-12 2022-10-20 Incyte Corporation Polythérapie comprenant un inhibiteur de fgfr et un agent de ciblage de nectine-4
EP4352059A1 (fr) 2021-06-09 2024-04-17 Incyte Corporation Hétérocycles tricycliques en tant qu'inhibiteurs de fgfr

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605642A (en) 1984-02-23 1986-08-12 The Salk Institute For Biological Studies CRF antagonists
US5063245A (en) 1990-03-28 1991-11-05 Nova Pharmaceutical Corporation Corticotropin-releasing factor antagonism compounds
GB9300059D0 (en) * 1992-01-20 1993-03-03 Zeneca Ltd Quinazoline derivatives
TW444018B (en) * 1992-12-17 2001-07-01 Pfizer Pyrazolopyrimidines
KR19990067704A (ko) * 1992-12-17 1999-08-25 디. 제이. 우드, 스피겔 알렌 제이 부신피질자극호르몬 유리인자 길항제로서의 피롤로피리미딘을함유하는 약학 조성물
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
TW530047B (en) * 1994-06-08 2003-05-01 Pfizer Corticotropin releasing factor antagonists
JP2891544B2 (ja) * 1994-06-16 1999-05-17 ファイザー・インコーポレーテッド ピラゾロおよびピロロピリジン類
JP2898887B2 (ja) * 1994-08-31 1999-06-02 沖電気工業株式会社 Icカードの読み取り装置
EP0729758A3 (fr) * 1995-03-02 1997-10-29 Pfizer Pyrazolopyrimidines et pyrrolopyrimidines pour traiter les troubles neuronaux et autres maladies
US6020492A (en) * 1995-05-12 2000-02-01 Neurogen Corporation Deazapurine derivatives; a new class of CRF1 specific ligands
US6403599B1 (en) * 1995-11-08 2002-06-11 Pfizer Inc Corticotropin releasing factor antagonists
DK0778277T3 (da) * 1995-12-08 2003-10-27 Pfizer Substituerede heterocycliske derivater som CRF antagonister
ES2168237T3 (es) 1996-02-07 2007-04-01 Neurocrine Biosciences, Inc. Pirazolopirimidinas como antagonistas de receptores de crf.
TW477787B (en) 1996-08-27 2002-03-01 Pfizer Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same

Also Published As

Publication number Publication date
HRP970432A2 (en) 1998-08-31
KR20000029843A (ko) 2000-05-25
UY24655A1 (es) 2000-09-29
DK0920429T3 (da) 2003-05-12
ID17980A (id) 1998-02-12
GT199700089A (es) 1999-01-26
MA24296A1 (fr) 1998-04-01
CZ41199A3 (cs) 2000-01-12
PL331602A1 (en) 1999-08-02
DE69719193T2 (de) 2003-09-25
DE69719193D1 (de) 2003-03-27
HRP970432B1 (en) 2002-10-31
JP2000501116A (ja) 2000-02-02
EA199900083A1 (ru) 1999-08-26
CN1227552A (zh) 1999-09-01
YU5399A (sh) 2002-03-18
OA10970A (en) 2001-11-05
SA97180334A (ar) 2005-12-03
CN1093130C (zh) 2002-10-23
AU709203B2 (en) 1999-08-26
TW550265B (en) 2003-09-01
BG103143A (en) 1999-09-30
CA2262692C (fr) 2002-06-11
ZA976954B (en) 1999-02-05
EP0920429A1 (fr) 1999-06-09
TNSN97135A1 (fr) 2005-03-15
NO313293B1 (no) 2002-09-09
NZ333727A (en) 2000-09-29
AR008829A1 (es) 2000-02-23
AP9701052A0 (en) 1997-10-31
NO990544D0 (no) 1999-02-05
TR199900228T2 (xx) 1999-03-22
AP1096A (en) 2002-08-26
AU3356397A (en) 1998-02-25
NO990544L (no) 1999-03-31
ATE232863T1 (de) 2003-03-15
CO4900060A1 (es) 2000-03-27
SK14099A3 (en) 2000-05-16
PA8435201A1 (es) 1999-12-27
WO1998005661A1 (fr) 1998-02-12
PE97098A1 (es) 1999-01-12
EA003188B1 (ru) 2003-02-27
BR9710808A (pt) 1999-08-17
IS4948A (is) 1999-01-19
CA2262692A1 (fr) 1998-02-12
JP3345021B2 (ja) 2002-11-18
CZ292806B6 (cs) 2003-12-17
US6492520B1 (en) 2002-12-10
HK1021734A1 (en) 2000-06-30
IL128188A0 (en) 1999-11-30
ES2191183T3 (es) 2003-09-01
EP0920429B1 (fr) 2003-02-19

Similar Documents

Publication Publication Date Title
DZ2289A1 (fr) Dérivés 6,6-ou 6,7 bicycliques à noyau pyrido ou pyrimido substitués.
MX9202838A (es) Imidazo[1,5-a]quinoxalinas.
NO974595D0 (no) Imidazo£1,2-a|pyridin-derivater
IS4963A (is) Setnar 6,5-heteró-bísýklískar afleiður
TR199800085A3 (tr) 8-Sübstitüye edilmis-1,3,8-triaza- spiro(4,5)dekan-4-on türevleri.
NO954090L (no) 1,5 Benzodiazepin-derivater med CCK-antagonistisk eller agonistisk aktivitet
AP9701076A0 (en) Substituted 6,6-hetero bicyclic derivatives
DK0921125T3 (da) 1,3,8-triazaspiro[4.5]decan-4-on-derivater
TR199600482A1 (tr) Trisiklik 5,6-dihidro-9H-pirazolo(3,4-c)-1,2,4-triazolo (4,3-a) piridinler.
TR199901381A3 (tr) Diaza-spiro[3,5]nonan türevleri.
BR9701675A (pt) Novos pirimido(1,2-a)indóis
NO982843L (no) 2,7-Substituerte oktahydro-pyrrol£1,2-a|pyrazin-derivater
FI923290A0 (fi) Imidazo (2,1-b)bensotiazol-3 -acetamidderivat.
FI906270A0 (fi) Imidazo/4,5-c/pyridiner som antiosteoporotiska aemnen.
FI904017A0 (fi) Pyrido/3,4-b/1,4/bensoxazepiner, foerfarande foer framstaellning av dessa och anvaendning av dessa som laekemedel.
NO983007D0 (no) Tieno(2,3-b)pyrazolo(3,4.d)pyridin-3-oner for Õ °ke erytropoese
TR199700219A3 (tr) 1,25-Dihidroksi-16, 22, 23-Trisdihidro-kolkalsiferol türevleri.
ES1031146Y (es) Estructura perfeccionada para el montaje de un tobogan infantil.
ZA200203580B (en) Bicyclic imidazo-3-yl-amine derivatives which are substituted on the sixth ring.
DE69014784D1 (de) Antivirale Tetrahydroimidazo[1,4]benzodiazepine.
ES1039020Y (es) Tarjeta-llavero multiusos.
ES1025258Y (es) Llavero multiuso perfeccionado.
FI1336U1 (fi) Vaermevaexlare foer uppvaermning av uteluft med vatten, skaerkilt i s.k. vertikalvindkraftverk
ES1035409Y (es) Llavero perfeccionado.
ES1033823Y (es) Llavero perfeccionado.