DK2542590T4 - Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner - Google Patents

Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner Download PDF

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Publication number
DK2542590T4
DK2542590T4 DK11751481.0T DK11751481T DK2542590T4 DK 2542590 T4 DK2542590 T4 DK 2542590T4 DK 11751481 T DK11751481 T DK 11751481T DK 2542590 T4 DK2542590 T4 DK 2542590T4
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compositions
procedure
fusion proteins
immunomodulatory antibodies
targeted immunomodulatory
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DK11751481.0T
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Danish (da)
English (en)
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DK2542590T3 (en
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Atul Bedi
Rajani Ravi
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Univ Johns Hopkins
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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DK11751481.0T 2010-03-05 2011-03-04 Sammensætninger og fremgangsmåde til målrettede immunomodulatoriske antistof-fer og fusionproteiner DK2542590T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31125510P 2010-03-05 2010-03-05
US201161435671P 2011-01-24 2011-01-24
PCT/US2011/027317 WO2011109789A2 (en) 2010-03-05 2011-03-04 Compositions and methods for targeted immunomodulatory antibodies and fusion proteins

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DK2542590T3 DK2542590T3 (en) 2017-08-28
DK2542590T4 true DK2542590T4 (da) 2020-07-13

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US (7) US8993524B2 (https=)
EP (3) EP2542590B2 (https=)
JP (4) JP6066732B2 (https=)
CA (3) CA3253628A1 (https=)
DK (1) DK2542590T4 (https=)
ES (1) ES2638521T5 (https=)
IL (5) IL300733B2 (https=)
PL (1) PL2542590T5 (https=)
PT (1) PT2542590T (https=)
WO (1) WO2011109789A2 (https=)

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DK2257301T3 (da) 2008-03-03 2014-04-28 Univ Miami Immunterapi baseret på allogene cancerceller.
EP3255060A1 (en) 2008-12-09 2017-12-13 F. Hoffmann-La Roche AG Anti-pd-l1 antibodies and their use to enhance t-cell function
KR101790802B1 (ko) 2009-09-03 2017-10-27 머크 샤프 앤드 돔 코포레이션 항-ｇｉｔｒ 항체
WO2011066342A2 (en) * 2009-11-24 2011-06-03 Amplimmune, Inc. Simultaneous inhibition of pd-l1/pd-l2
CA3253628A1 (en) 2010-03-05 2025-11-29 The Johns Hopkins University Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
EP3604339B1 (en) 2011-01-14 2021-03-10 The Regents Of The University Of California Therapeutic antibodies against ror-1 protein and methods for use of same
CN103561771B (zh) 2011-03-17 2019-01-04 伯明翰大学 重新定向的免疫治疗
JP6047142B2 (ja) * 2011-04-01 2016-12-21 ウニヴェルズィテート シュトゥットガルト 抗体結合ドメインを有する組換えｔｎｆリガンドファミリーメンバーポリペプチドおよびそれらの使用
JP6055615B2 (ja) 2011-05-27 2016-12-27 アッヴィ バイオテクノロジー リミテッド Ｄａｃｈｙｐ組成物および方法
WO2013056240A1 (en) 2011-10-13 2013-04-18 Aerpio Therapeutics, Inc. Methods for treating vascular leak syndrome and cancer
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