DK2300465T3 - Imidazopyridinderivater som hæmmere af receptortyrosinkinaser - Google Patents

Imidazopyridinderivater som hæmmere af receptortyrosinkinaser Download PDF

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Publication number
DK2300465T3
DK2300465T3 DK09761801.1T DK09761801T DK2300465T3 DK 2300465 T3 DK2300465 T3 DK 2300465T3 DK 09761801 T DK09761801 T DK 09761801T DK 2300465 T3 DK2300465 T3 DK 2300465T3
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Prior art keywords
receptoryrosinkinases
imidazopyridin
derivatives
understanding
understanding receptoryrosinkinases
Prior art date
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DK09761801.1T
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Danish (da)
English (en)
Inventor
Valerio Berdini
Maria Grazia Carr
Miles Stuart Congreve
Martyn Frederickson
Charlotte Mary Griffiths-Jones
Christopher Charles Frederick Hamlett
Christopher William Murray
Rajdeep Kaur Benning
Gordon Saxty
Emma Vickerstaffe
Andrew James Woodhead
Eddy Jean Edgard Freyne
Tom Cornelis Hortense Govaerts
Patrick René Angibaud
Andrew Madin
Steven John Woodhead
Brian John Williams
Original Assignee
Astex Therapeutics Ltd
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Publication of DK2300465T3 publication Critical patent/DK2300465T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK09761801.1T 2008-06-13 2009-06-12 Imidazopyridinderivater som hæmmere af receptortyrosinkinaser DK2300465T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6118408P 2008-06-13 2008-06-13
GBGB0810902.7A GB0810902D0 (en) 2008-06-13 2008-06-13 New compounds
PCT/EP2009/057318 WO2009150240A1 (en) 2008-06-13 2009-06-12 Imidazopyridine derivatives as inhibitors of receptor tyrosine kinases

Publications (1)

Publication Number Publication Date
DK2300465T3 true DK2300465T3 (da) 2019-06-24

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DK09761801.1T DK2300465T3 (da) 2008-06-13 2009-06-12 Imidazopyridinderivater som hæmmere af receptortyrosinkinaser

Country Status (21)

Country Link
US (1) US8796244B2 (enExample)
EP (1) EP2300465B1 (enExample)
JP (1) JP5596023B2 (enExample)
KR (1) KR101745730B1 (enExample)
CN (1) CN102137859B (enExample)
AU (1) AU2009256584B2 (enExample)
BR (1) BRPI0915084B8 (enExample)
CA (1) CA2727062A1 (enExample)
DK (1) DK2300465T3 (enExample)
ES (1) ES2735979T3 (enExample)
GB (1) GB0810902D0 (enExample)
HR (1) HRP20191027T1 (enExample)
HU (1) HUE045300T2 (enExample)
IL (1) IL209864A (enExample)
LT (1) LT2300465T (enExample)
MX (1) MX2010013743A (enExample)
NZ (1) NZ589781A (enExample)
RU (1) RU2518089C2 (enExample)
SI (1) SI2300465T1 (enExample)
WO (1) WO2009150240A1 (enExample)
ZA (1) ZA201008961B (enExample)

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KR20110017000A (ko) 2011-02-18
JP2011522866A (ja) 2011-08-04
BRPI0915084B8 (pt) 2021-05-25
IL209864A (en) 2015-10-29
AU2009256584B2 (en) 2014-06-12
JP5596023B2 (ja) 2014-09-24
AU2009256584A1 (en) 2009-12-17
RU2518089C2 (ru) 2014-06-10
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GB0810902D0 (en) 2008-07-23
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EP2300465A1 (en) 2011-03-30
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SI2300465T1 (sl) 2019-08-30
ZA201008961B (en) 2015-05-27
BRPI0915084A2 (pt) 2015-10-27
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