LT2300465T - Imidazopiridino dariniai kaip receptoriaus tirozino kinazių inhibitoriai - Google Patents

Imidazopiridino dariniai kaip receptoriaus tirozino kinazių inhibitoriai

Info

Publication number
LT2300465T
LT2300465T LTEP09761801.1T LT09761801T LT2300465T LT 2300465 T LT2300465 T LT 2300465T LT 09761801 T LT09761801 T LT 09761801T LT 2300465 T LT2300465 T LT 2300465T
Authority
LT
Lithuania
Prior art keywords
inhibitors
receptor tyrosine
tyrosine kinases
imidazopyridine derivatives
imidazopyridine
Prior art date
Application number
LTEP09761801.1T
Other languages
English (en)
Inventor
Valerio Berdini
Maria Carr
Miles Congreve
Martyn Frederickson
Charlotte GRIFFITHS-JONES
Christopher Hamlett
Andrew Madin
Christopher Murray
Rajdeep Kaur Benning
Gordon Saxty
Emma Vickerstaffe
Andrew Woodhead
Steven Woodhead
Eddy Freyne
Tom GOVAERTS
Patrick Angibaud
Brian Williams
Original Assignee
Astex Therapeutics Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astex Therapeutics Limited filed Critical Astex Therapeutics Limited
Publication of LT2300465T publication Critical patent/LT2300465T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
LTEP09761801.1T 2008-06-13 2009-06-12 Imidazopiridino dariniai kaip receptoriaus tirozino kinazių inhibitoriai LT2300465T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6118408P 2008-06-13 2008-06-13
GBGB0810902.7A GB0810902D0 (en) 2008-06-13 2008-06-13 New compounds
PCT/EP2009/057318 WO2009150240A1 (en) 2008-06-13 2009-06-12 Imidazopyridine derivatives as inhibitors of receptor tyrosine kinases

Publications (1)

Publication Number Publication Date
LT2300465T true LT2300465T (lt) 2019-06-25

Family

ID=39672279

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP09761801.1T LT2300465T (lt) 2008-06-13 2009-06-12 Imidazopiridino dariniai kaip receptoriaus tirozino kinazių inhibitoriai

Country Status (21)

Country Link
US (1) US8796244B2 (lt)
EP (1) EP2300465B1 (lt)
JP (1) JP5596023B2 (lt)
KR (1) KR101745730B1 (lt)
CN (1) CN102137859B (lt)
AU (1) AU2009256584B2 (lt)
BR (1) BRPI0915084B8 (lt)
CA (1) CA2727062A1 (lt)
DK (1) DK2300465T3 (lt)
ES (1) ES2735979T3 (lt)
GB (1) GB0810902D0 (lt)
HR (1) HRP20191027T1 (lt)
HU (1) HUE045300T2 (lt)
IL (1) IL209864A (lt)
LT (1) LT2300465T (lt)
MX (1) MX2010013743A (lt)
NZ (1) NZ589781A (lt)
RU (1) RU2518089C2 (lt)
SI (1) SI2300465T1 (lt)
WO (1) WO2009150240A1 (lt)
ZA (1) ZA201008961B (lt)

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JP5596023B2 (ja) 2014-09-24
DK2300465T3 (da) 2019-06-24
AU2009256584A1 (en) 2009-12-17
ES2735979T3 (es) 2019-12-23
IL209864A (en) 2015-10-29
RU2518089C2 (ru) 2014-06-10
WO2009150240A1 (en) 2009-12-17
NZ589781A (en) 2013-02-22
CA2727062A1 (en) 2009-12-17
BRPI0915084B1 (pt) 2020-02-11
HRP20191027T1 (hr) 2019-11-29
EP2300465A1 (en) 2011-03-30
EP2300465B1 (en) 2019-04-17
BRPI0915084A2 (pt) 2015-10-27
SI2300465T1 (sl) 2019-08-30
KR101745730B1 (ko) 2017-06-12
ZA201008961B (en) 2015-05-27
GB0810902D0 (en) 2008-07-23
HUE045300T2 (hu) 2019-12-30
JP2011522866A (ja) 2011-08-04
AU2009256584B2 (en) 2014-06-12
KR20110017000A (ko) 2011-02-18
IL209864A0 (en) 2011-02-28
US20120208791A1 (en) 2012-08-16
RU2011100786A (ru) 2012-07-20
CN102137859A (zh) 2011-07-27
MX2010013743A (es) 2011-02-15

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