DK174690A - Antibakterielle midler - Google Patents

Antibakterielle midler Download PDF

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Publication number
DK174690A
DK174690A DK174690A DK174690A DK174690A DK 174690 A DK174690 A DK 174690A DK 174690 A DK174690 A DK 174690A DK 174690 A DK174690 A DK 174690A DK 174690 A DK174690 A DK 174690A
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DK
Denmark
Prior art keywords
antibacterial agents
manufacture
formulation
methods
well
Prior art date
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DK174690A
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English (en)
Other versions
DK173057B1 (da
DK174690D0 (da
Inventor
John Michael Domagala
Susan Elizabeth Hagen
John Steven Kiely
Original Assignee
Warner Lambert Co
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Filing date
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Publication of DK174690D0 publication Critical patent/DK174690D0/da
Publication of DK174690A publication Critical patent/DK174690A/da
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Publication of DK173057B1 publication Critical patent/DK173057B1/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK199001746A 1988-01-25 1990-07-20 5-Alkyl-6-fluor-1,4-dihydro-4-oxo-1,8-naphthyridinforbindelser, fremgangsmåder til fremstilling deraf, farmaceutisk præpara DK173057B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US14746288A 1988-01-25 1988-01-25
US14746288 1988-01-25
US07/280,924 US4920120A (en) 1988-01-25 1988-12-09 Antibacterial agents
US28092488 1988-12-09
PCT/US1989/000278 WO1989006649A2 (en) 1988-01-25 1989-01-23 Antibacterial agents
US8900278 1989-01-23

Publications (3)

Publication Number Publication Date
DK174690D0 DK174690D0 (da) 1990-07-20
DK174690A true DK174690A (da) 1990-07-20
DK173057B1 DK173057B1 (da) 1999-12-13

Family

ID=26844956

Family Applications (2)

Application Number Title Priority Date Filing Date
DK199001746A DK173057B1 (da) 1988-01-25 1990-07-20 5-Alkyl-6-fluor-1,4-dihydro-4-oxo-1,8-naphthyridinforbindelser, fremgangsmåder til fremstilling deraf, farmaceutisk præpara
DK140996A DK140996A (da) 1988-01-25 1996-12-09 Fremgangsmåde til fremstilling af 2,3,4,5-tetraflour-6-alkyl-benzoesyreforbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK140996A DK140996A (da) 1988-01-25 1996-12-09 Fremgangsmåde til fremstilling af 2,3,4,5-tetraflour-6-alkyl-benzoesyreforbindelser

Country Status (16)

Country Link
US (1) US4920120A (da)
EP (2) EP0398967A1 (da)
JP (2) JP2815119B2 (da)
KR (3) KR0130931B1 (da)
AT (1) ATE109471T1 (da)
AU (4) AU624118B2 (da)
CA (1) CA1340492C (da)
DE (1) DE68917163T2 (da)
DK (2) DK173057B1 (da)
ES (1) ES2056963T3 (da)
FI (1) FI93360C (da)
IE (1) IE65350B1 (da)
NO (2) NO178194C (da)
NZ (1) NZ227680A (da)
PT (1) PT89520B (da)
WO (1) WO1989006649A2 (da)

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ATE365152T1 (de) * 1998-09-14 2007-07-15 Otsuka Pharma Co Ltd Verfahren zur herstellung fluorierter benzoesäuren
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Also Published As

Publication number Publication date
KR900700475A (ko) 1990-08-13
WO1989006649A3 (en) 1989-12-28
FI93360C (fi) 1995-03-27
DK173057B1 (da) 1999-12-13
JPH10291959A (ja) 1998-11-04
PT89520B (pt) 1994-02-28
KR19980703084A (ko) 1998-09-05
NO942468D0 (no) 1994-06-30
AU659444B2 (en) 1995-05-18
PT89520A (pt) 1989-10-04
KR0182275B1 (ko) 1999-05-01
AU2722495A (en) 1995-10-05
DE68917163D1 (de) 1994-09-08
AU624118B2 (en) 1992-06-04
JP2815119B2 (ja) 1998-10-27
AU674272B2 (en) 1996-12-12
AU1388892A (en) 1992-07-09
EP0398967A1 (en) 1990-11-28
AU2722395A (en) 1995-10-19
DK140996A (da) 1996-12-09
DE68917163T2 (de) 1994-12-01
NO300263B1 (no) 1997-05-05
DK174690D0 (da) 1990-07-20
NO942468L (no) 1990-07-24
NO178194B (no) 1995-10-30
IE883900L (en) 1989-07-25
EP0326891A2 (en) 1989-08-09
ES2056963T3 (es) 1994-10-16
KR0130931B1 (ko) 1998-04-16
CA1340492C (en) 1999-04-13
FI903696A0 (fi) 1990-07-23
IE65350B1 (en) 1995-10-18
EP0326891B1 (en) 1994-08-03
EP0326891A3 (en) 1990-04-25
FI93360B (fi) 1994-12-15
NO178194C (no) 1996-02-07
ATE109471T1 (de) 1994-08-15
NO903286L (no) 1990-07-24
NZ227680A (en) 1991-11-26
NO903286D0 (no) 1990-07-24
AU3048389A (en) 1989-08-11
US4920120A (en) 1990-04-24
JPH03502452A (ja) 1991-06-06
KR0145958B1 (en) 1998-08-17
WO1989006649A2 (en) 1989-07-27
AU671575B2 (en) 1996-08-29
JP2986154B2 (ja) 1999-12-06

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