DK172655B1 - Fremgangsmåde til fremstilling af 5-chlor-3-chlorsulfonyl-2-thiophencarboxylsyreestere ved chlorering under tilstedeværelse - Google Patents

Fremgangsmåde til fremstilling af 5-chlor-3-chlorsulfonyl-2-thiophencarboxylsyreestere ved chlorering under tilstedeværelse Download PDF

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Publication number
DK172655B1
DK172655B1 DK198902111A DK211189A DK172655B1 DK 172655 B1 DK172655 B1 DK 172655B1 DK 198902111 A DK198902111 A DK 198902111A DK 211189 A DK211189 A DK 211189A DK 172655 B1 DK172655 B1 DK 172655B1
Authority
DK
Denmark
Prior art keywords
compound
iron
gaseous chlorine
chlorination
process according
Prior art date
Application number
DK198902111A
Other languages
Danish (da)
English (en)
Other versions
DK211189D0 (da
DK211189A (da
Inventor
Hans Peter Wagner
Original Assignee
Nycomed Danmark As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Danmark As filed Critical Nycomed Danmark As
Publication of DK211189D0 publication Critical patent/DK211189D0/da
Publication of DK211189A publication Critical patent/DK211189A/da
Application granted granted Critical
Publication of DK172655B1 publication Critical patent/DK172655B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK198902111A 1988-05-02 1989-05-01 Fremgangsmåde til fremstilling af 5-chlor-3-chlorsulfonyl-2-thiophencarboxylsyreestere ved chlorering under tilstedeværelse DK172655B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0112388A AT390060B (de) 1988-05-02 1988-05-02 Verfahren zur herstellung von 5-chlor-3chlorsulfonyl-2-thiophencarbonsaeureestern
AT112388 1988-05-02

Publications (3)

Publication Number Publication Date
DK211189D0 DK211189D0 (da) 1989-05-01
DK211189A DK211189A (da) 1989-11-03
DK172655B1 true DK172655B1 (da) 1999-04-12

Family

ID=3507085

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198902111A DK172655B1 (da) 1988-05-02 1989-05-01 Fremgangsmåde til fremstilling af 5-chlor-3-chlorsulfonyl-2-thiophencarboxylsyreestere ved chlorering under tilstedeværelse

Country Status (28)

Country Link
US (1) US5138072A (zh)
EP (1) EP0340472B1 (zh)
JP (1) JP2785132B2 (zh)
KR (1) KR970000685B1 (zh)
CN (1) CN1028101C (zh)
AT (2) AT390060B (zh)
AU (1) AU614058B2 (zh)
CA (1) CA1333177C (zh)
CS (1) CS275851B6 (zh)
CY (1) CY1756A (zh)
DD (1) DD283818A5 (zh)
DE (1) DE58905010D1 (zh)
DK (1) DK172655B1 (zh)
EG (1) EG20136A (zh)
ES (1) ES2058372T3 (zh)
FI (1) FI86062C (zh)
GR (1) GR3008623T3 (zh)
HK (1) HK128193A (zh)
HU (1) HU202518B (zh)
IL (1) IL89902A0 (zh)
MY (1) MY103874A (zh)
NO (1) NO171912C (zh)
NZ (1) NZ228772A (zh)
PH (1) PH27581A (zh)
SA (1) SA89100027B1 (zh)
SU (1) SU1704632A3 (zh)
YU (1) YU48507B (zh)
ZA (1) ZA892791B (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4232417A1 (de) * 1992-09-28 1994-03-31 Bayer Ag Substituierte Thienylsulfonylharnstoffe
DE19540737A1 (de) * 1995-11-02 1997-05-07 Bayer Ag Substituierte Sulfonylamino(thio)carbonylverbindungen
CN103356636A (zh) 2004-05-23 2013-10-23 杰勒德·M·豪斯 Theramutein调节剂
US8431110B2 (en) 2005-05-23 2013-04-30 Hmi Medical Innovations, Llc. Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
JP2009523408A (ja) * 2005-11-23 2009-06-25 ジェラルド・エム・ハウシー タンパク質モジュレーターを同定、合成、最適化および解析する化合物群および方法群
CN116693498B (zh) * 2023-05-30 2024-01-30 湖北广济医药科技有限公司 一种利用连续流动反应合成5-氯-3-(氯磺酰基)-2-噻吩羧酸甲酯的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE698778C (de) * 1934-11-11 1941-07-10 I G Farbenindustrie Akt Ges Verfahren zur Herstellung von organischen Monochlor- oder Monobromverbindungen
DE2227439B2 (de) * 1972-06-06 1977-05-05 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Chlorierung oder bromierung phenolischer verbindungen
DE2534689B2 (de) * 1974-09-16 1979-03-01 Basf Ag, 6700 Ludwigshafen 23-Dihydro-3-oxo-thieno-isothiazol-1,1-dioxide
AU518216B2 (en) * 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
GB2159156A (en) * 1984-05-24 1985-11-27 Du Pont Process for the preparation of alkyl 3-chlorosulfonylthiophene-2-carboxylate
FI862513A (fi) * 1985-07-04 1987-01-05 Chemie Linz Ag Nya tieno-1,2-tiazolderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska preparat.
EP0245835B1 (en) * 1986-05-13 1993-05-05 Seitetsu Kagaku Co., Ltd. Novel thiophene derivatives and methods for producing the same

Also Published As

Publication number Publication date
FI86062C (fi) 1992-07-10
AU614058B2 (en) 1991-08-15
DD283818A5 (de) 1990-10-24
DE58905010D1 (de) 1993-09-02
CS275851B6 (en) 1992-03-18
JP2785132B2 (ja) 1998-08-13
FI892051A0 (fi) 1989-04-28
NO891679L (no) 1989-11-03
DK211189D0 (da) 1989-05-01
ES2058372T3 (es) 1994-11-01
YU81089A (en) 1990-06-30
ATA112388A (de) 1989-08-15
KR890017240A (ko) 1989-12-15
ATE92056T1 (de) 1993-08-15
YU48507B (sh) 1998-09-18
FI86062B (fi) 1992-03-31
NO171912B (no) 1993-02-08
AT390060B (de) 1990-03-12
AU3380189A (en) 1989-11-02
MY103874A (en) 1993-09-30
US5138072A (en) 1992-08-11
GR3008623T3 (zh) 1993-10-29
PH27581A (en) 1993-08-18
HK128193A (en) 1993-11-26
HU202518B (en) 1991-03-28
HUT49869A (en) 1989-11-28
NZ228772A (en) 1990-09-26
EP0340472B1 (de) 1993-07-28
JPH01313474A (ja) 1989-12-18
SA89100027B1 (ar) 2003-04-09
ZA892791B (en) 1989-12-27
CA1333177C (en) 1994-11-22
DK211189A (da) 1989-11-03
CY1756A (en) 1994-06-03
EP0340472A1 (de) 1989-11-08
CN1028101C (zh) 1995-04-05
EG20136A (en) 1997-07-31
NO171912C (no) 1993-05-19
CN1037511A (zh) 1989-11-29
IL89902A0 (en) 1989-12-15
SU1704632A3 (ru) 1992-01-07
KR970000685B1 (ko) 1997-01-18
FI892051A (fi) 1989-11-03
NO891679D0 (no) 1989-04-24

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
B1 Patent granted (law 1993)
PUP Patent expired