DK169476B1 - Carbapenemderivater og fremgangsmåde til fremstilling deraf samt midler indeholdende dem - Google Patents

Carbapenemderivater og fremgangsmåde til fremstilling deraf samt midler indeholdende dem Download PDF

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Publication number
DK169476B1
DK169476B1 DK138885A DK138885A DK169476B1 DK 169476 B1 DK169476 B1 DK 169476B1 DK 138885 A DK138885 A DK 138885A DK 138885 A DK138885 A DK 138885A DK 169476 B1 DK169476 B1 DK 169476B1
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compound
formula
group
defined above
compounds
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DK138885A
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Danish (da)
English (en)
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DK138885A (da
DK138885D0 (da
Inventor
Masayuki Iwata
Yukio Sugimura
Toshihiko Hashimoto
Teruo Tanaka
Kimio Iino
Tomoyuki Shibata
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Sankyo Co
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Publication of DK138885D0 publication Critical patent/DK138885D0/da
Publication of DK138885A publication Critical patent/DK138885A/da
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Publication of DK169476B1 publication Critical patent/DK169476B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/26—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DK138885A 1984-03-27 1985-03-27 Carbapenemderivater og fremgangsmåde til fremstilling deraf samt midler indeholdende dem DK169476B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59059279A JPS60202886A (ja) 1984-03-27 1984-03-27 １―置換カルバペネム―３―カルボン酸誘導体
JP5927984 1984-03-27

Publications (3)

Publication Number Publication Date
DK138885D0 DK138885D0 (da) 1985-03-27
DK138885A DK138885A (da) 1985-09-28
DK169476B1 true DK169476B1 (da) 1994-11-07

Family

ID=13108786

Family Applications (1)

Application Number Title Priority Date Filing Date
DK138885A DK169476B1 (da) 1984-03-27 1985-03-27 Carbapenemderivater og fremgangsmåde til fremstilling deraf samt midler indeholdende dem

Country Status (17)

Country Link
US (1) US5102997A (de)
EP (1) EP0160391B1 (de)
JP (1) JPS60202886A (de)
KR (1) KR910010049B1 (de)
AT (1) ATE86255T1 (de)
AU (1) AU582148B2 (de)
DE (1) DE3587126T2 (de)
DK (1) DK169476B1 (de)
ES (2) ES8702912A1 (de)
FI (1) FI83419C (de)
HU (1) HU196800B (de)
IE (1) IE59708B1 (de)
NO (1) NO164980C (de)
NZ (1) NZ211604A (de)
PH (1) PH25057A (de)
SU (2) SU1501922A3 (de)
ZA (1) ZA852251B (de)

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CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
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JPS63255280A (ja) * 1987-04-11 1988-10-21 Nippon Redarii Kk （１ｒ，５ｓ，６ｓ）−２−置換−６−〔（ｒ）−１−ヒドロキシエチル〕−１−メチル−カルバペネム−３−カルボン酸誘導体
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US4963544A (en) * 1988-05-23 1990-10-16 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
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GB8923844D0 (en) * 1989-10-23 1989-12-13 Fujisawa Pharmaceutical Co Carbapenem compounds
FI96311C (fi) * 1989-12-04 1996-06-10 Squibb Bristol Myers Co Menetelmä farmaseuttisesti käyttökelpoisten 6-(1-hydroksietyyli)-3-(substituoitu tio)-7-okso-1-atsabisyklo/3.2.0/hept-2-eeni-2-karboksyylihappojohdannaisten valmistamiseksi
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US5672701A (en) * 1990-01-16 1997-09-30 Bristol-Myers Squibb Company 4-substituted alkyl carbapenem antibiotics
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US5208348A (en) * 1990-09-07 1993-05-04 Tanabe Seiyaku Co., Ltd. Mercaptan compound
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GB9107341D0 (en) * 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
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CA2091309A1 (en) * 1992-03-26 1993-09-27 Frederic H. Jung Antibiotic compounds
GB9304156D0 (en) * 1992-03-26 1993-04-21 Zeneca Ltd Antibiotic compounds
EP0937725A3 (de) 1992-04-28 2004-12-01 Tanabe Seiyaku Co., Ltd. Verfahren, um eine geschützte HO-Gruppe freizumachen
US5587474A (en) * 1992-06-18 1996-12-24 Tanabe Seiyaku Co., Ltd. Method for removing the protecting group for carboxyl group
CA2099811A1 (en) * 1992-07-21 1994-01-22 Frederic H. Jung Antibiotic compounds
CA2099818A1 (en) * 1992-07-21 1994-01-22 Frederic H. Jung Antibiotic compounds
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KR940007029A (ko) * 1992-09-02 1994-04-26 손정삼 새로운 카바페넴 유도체 및 그의 제조방법
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US5631363A (en) * 1992-11-13 1997-05-20 Tanabe Seiyaku Co., Ltd. Azetidinone compound and process for preparation thereof
US6011150A (en) * 1992-11-13 2000-01-04 Tanabe Seiyaku Co., Ltd. Azetidinone compound and process for preparation thereof
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US5550229A (en) * 1993-06-23 1996-08-27 Tanabe Seiyaku Co., Ltd. Alkylation process for preparing azetidinone compound and starting compound therefor
AU682510B2 (en) * 1993-07-01 1997-10-09 Pfizer Japan Inc. 2-(1-(1,3-thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives
US5783703A (en) * 1993-07-01 1998-07-21 Lederle (Japan), Ltd. Sulfur-containing compounds method for their use and prodction
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Also Published As

Publication number Publication date
ATE86255T1 (de) 1993-03-15
JPS60202886A (ja) 1985-10-14
IE850776L (en) 1985-09-27
FI851240L (fi) 1985-09-28
HUT38351A (en) 1986-05-28
JPH0367068B2 (de) 1991-10-21
KR910010049B1 (ko) 1991-12-12
ES550907A0 (es) 1987-02-16
SU1501922A3 (ru) 1989-08-15
DK138885A (da) 1985-09-28
NO164980C (no) 1990-12-05
SU1591810A3 (ru) 1990-09-07
FI83419B (fi) 1991-03-28
ZA852251B (en) 1985-12-24
KR850006418A (ko) 1985-10-05
ES541638A0 (es) 1987-01-16
DK138885D0 (da) 1985-03-27
FI83419C (fi) 1991-07-10
DE3587126T2 (de) 1993-10-07
NZ211604A (en) 1989-01-06
NO164980B (no) 1990-08-27
PH25057A (en) 1991-01-28
US5102997A (en) 1992-04-07
EP0160391A1 (de) 1985-11-06
NO851227L (no) 1985-09-30
FI851240A0 (fi) 1985-03-27
ES8703473A1 (es) 1987-02-16
EP0160391B1 (de) 1993-03-03
ES8702912A1 (es) 1987-01-16
IE59708B1 (en) 1994-03-23
AU4043185A (en) 1985-10-03
HU196800B (en) 1989-01-30
AU582148B2 (en) 1989-03-16
DE3587126D1 (de) 1993-04-08

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