DK138885D0 - Carbapenemderivater og midler med indhold heraf - Google Patents
Carbapenemderivater og midler med indhold herafInfo
- Publication number
- DK138885D0 DK138885D0 DK138885A DK138885A DK138885D0 DK 138885 D0 DK138885 D0 DK 138885D0 DK 138885 A DK138885 A DK 138885A DK 138885 A DK138885 A DK 138885A DK 138885 D0 DK138885 D0 DK 138885D0
- Authority
- DK
- Denmark
- Prior art keywords
- sup
- contents contained
- carbapenem derivatives
- optionally substituted
- carbapenem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/26—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5927984 | 1984-03-27 | ||
JP59059279A JPS60202886A (ja) | 1984-03-27 | 1984-03-27 | 1―置換カルバペネム―3―カルボン酸誘導体 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK138885D0 true DK138885D0 (da) | 1985-03-27 |
DK138885A DK138885A (da) | 1985-09-28 |
DK169476B1 DK169476B1 (da) | 1994-11-07 |
Family
ID=13108786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK138885A DK169476B1 (da) | 1984-03-27 | 1985-03-27 | Carbapenemderivater og fremgangsmåde til fremstilling deraf samt midler indeholdende dem |
Country Status (17)
Country | Link |
---|---|
US (1) | US5102997A (da) |
EP (1) | EP0160391B1 (da) |
JP (1) | JPS60202886A (da) |
KR (1) | KR910010049B1 (da) |
AT (1) | ATE86255T1 (da) |
AU (1) | AU582148B2 (da) |
DE (1) | DE3587126T2 (da) |
DK (1) | DK169476B1 (da) |
ES (2) | ES8702912A1 (da) |
FI (1) | FI83419C (da) |
HU (1) | HU196800B (da) |
IE (1) | IE59708B1 (da) |
NO (1) | NO164980C (da) |
NZ (1) | NZ211604A (da) |
PH (1) | PH25057A (da) |
SU (2) | SU1501922A3 (da) |
ZA (1) | ZA852251B (da) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1283906C (en) * | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
US4696923A (en) * | 1984-04-23 | 1987-09-29 | Merck & Co., Inc. | 6-[1-hydroxyethyl]-2-SR8 -1-methyl-1-carbadethiapen-2-em-3-carboxylic acids |
US4665169A (en) * | 1985-09-11 | 1987-05-12 | Bristol-Myers Company | Carbapenem antibiotics |
JPS6363680A (ja) * | 1986-09-05 | 1988-03-22 | Nippon Redarii Kk | (1r)−1−メチルカルバペネム−3−カルボン酸誘導体 |
DE3784147T2 (de) * | 1986-11-24 | 1993-06-03 | Fujisawa Pharmaceutical Co | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)hept-2-en-2-carbonsaeure-derivate. |
KR880006244A (ko) * | 1986-11-24 | 1988-07-22 | 후지사와 도모 기찌 로 | 3-피롤리디닐티오-1-아자바이스클로[3.2.0]햅트2-엔-2-카르복실산 화합물 및 이의 제조방법 |
JPS63255280A (ja) * | 1987-04-11 | 1988-10-21 | Nippon Redarii Kk | (1r,5s,6s)−2−置換−6−〔(r)−1−ヒドロキシエチル〕−1−メチル−カルバペネム−3−カルボン酸誘導体 |
US4925838A (en) * | 1988-03-18 | 1990-05-15 | Fujisawa Pharmaceutical Company, Ltd. | 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds |
US5242914A (en) * | 1988-04-01 | 1993-09-07 | Sankyo Company, Limited | 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics |
ES2067534T3 (es) * | 1988-04-01 | 1995-04-01 | Sankyo Co | Derivados de 2-(heterocicliltio)carbapenemo, su preparacion y su aplicacion como antibioticos. |
GB8811237D0 (en) * | 1988-05-12 | 1988-06-15 | Fujisawa Pharmaceutical Co | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives |
US4963544A (en) * | 1988-05-23 | 1990-10-16 | Fujisawa Pharmaceutical Company, Ltd. | 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds |
CA2022382A1 (en) * | 1989-08-02 | 1991-02-03 | Susumu Nakagawa | Piperidylthiocarbapenem derivatives |
GB8923844D0 (en) * | 1989-10-23 | 1989-12-13 | Fujisawa Pharmaceutical Co | Carbapenem compounds |
FI96311C (fi) * | 1989-12-04 | 1996-06-10 | Squibb Bristol Myers Co | Menetelmä farmaseuttisesti käyttökelpoisten 6-(1-hydroksietyyli)-3-(substituoitu tio)-7-okso-1-atsabisyklo/3.2.0/hept-2-eeni-2-karboksyylihappojohdannaisten valmistamiseksi |
WO1991009860A1 (en) * | 1989-12-28 | 1991-07-11 | Banyu Pharmaceutical Co., Ltd. | New carbapenem derivative |
US5672701A (en) * | 1990-01-16 | 1997-09-30 | Bristol-Myers Squibb Company | 4-substituted alkyl carbapenem antibiotics |
US5554606A (en) * | 1990-03-12 | 1996-09-10 | Zeneca Limited | Antibiotic compounds |
US5208348A (en) * | 1990-09-07 | 1993-05-04 | Tanabe Seiyaku Co., Ltd. | Mercaptan compound |
CA2050255C (en) * | 1990-09-07 | 1997-02-04 | Tameo Iwasaki | 1-methylcarbapenem derivatives and process for preparation thereof |
GB9107341D0 (en) * | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
GB9202298D0 (en) * | 1992-02-04 | 1992-03-18 | Ici Plc | Antibiotic compounds |
GB9304156D0 (en) * | 1992-03-26 | 1993-04-21 | Zeneca Ltd | Antibiotic compounds |
CA2091309A1 (en) * | 1992-03-26 | 1993-09-27 | Frederic H. Jung | Antibiotic compounds |
DE69329939T2 (de) * | 1992-04-28 | 2001-06-28 | Tanabe Seiyaku Co., Ltd. | Verfahrenzur Abspaltung von Silylschutzgruppen aus geschützten HO-Gruppen |
US5587474A (en) * | 1992-06-18 | 1996-12-24 | Tanabe Seiyaku Co., Ltd. | Method for removing the protecting group for carboxyl group |
CA2099817A1 (en) * | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
CA2099818A1 (en) * | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
CA2099811A1 (en) * | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
JP2696807B2 (ja) * | 1992-08-06 | 1998-01-14 | 田辺製薬株式会社 | カルバペネム誘導体の製法 |
KR940007029A (ko) * | 1992-09-02 | 1994-04-26 | 손정삼 | 새로운 카바페넴 유도체 및 그의 제조방법 |
CA2106141A1 (en) * | 1992-09-28 | 1994-03-29 | Michael J. Betts | Antibiotic compounds |
US5631363A (en) * | 1992-11-13 | 1997-05-20 | Tanabe Seiyaku Co., Ltd. | Azetidinone compound and process for preparation thereof |
US6011150A (en) * | 1992-11-13 | 2000-01-04 | Tanabe Seiyaku Co., Ltd. | Azetidinone compound and process for preparation thereof |
US5442055A (en) * | 1992-11-13 | 1995-08-15 | Tanabe Seiyaku Co., Ltd. | Azetidinone compound and process for preparation thereof |
US5602118A (en) * | 1993-03-16 | 1997-02-11 | American Cyanamid Company | 2-thiosubstituted carbapenems |
US5550229A (en) * | 1993-06-23 | 1996-08-27 | Tanabe Seiyaku Co., Ltd. | Alkylation process for preparing azetidinone compound and starting compound therefor |
AU682510B2 (en) * | 1993-07-01 | 1997-10-09 | Pfizer Japan Inc. | 2-(1-(1,3-thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives |
US5783703A (en) * | 1993-07-01 | 1998-07-21 | Lederle (Japan), Ltd. | Sulfur-containing compounds method for their use and prodction |
US5688786A (en) * | 1994-04-01 | 1997-11-18 | Microcide Pharmaceuticals, Inc. | β-lactam antibiotics |
AU4844896A (en) * | 1995-03-02 | 1996-09-18 | Takeda Chemical Industries Ltd. | Carbapenem compounds, their production and use |
AU5985596A (en) * | 1995-05-31 | 1996-12-18 | Microcide Pharmaceuticals, Inc. | Cephalosporin antibiotics |
TW420681B (en) * | 1995-12-08 | 2001-02-01 | Lederle Japan Ltd | Carbapenem-3-carboxylic acid ester derivatives |
US8729260B2 (en) * | 2010-05-19 | 2014-05-20 | Savior Lifetec Corporation | Process for the preparation of carbapenem using cabapenem intermediates and recovery of cabapenem |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2966497D1 (en) * | 1978-10-24 | 1984-01-26 | Merck & Co Inc | 6-, 1- and 2-substituted-1-carbapen-2-em-3-carboxylic acids, processes for the preparation of such compounds and pharmaceutical composition comprising such compounds |
US4260627A (en) * | 1978-10-24 | 1981-04-07 | Merck & Co., Inc. | 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids |
US4208422A (en) * | 1978-10-24 | 1980-06-17 | Merck & Co., Inc. | 1-Substituted-pen-2-em-3-carboxylic acids |
US4206219A (en) * | 1978-10-24 | 1980-06-03 | Merck & Co., Inc. | 6- and 1-Substituted-1-carbadethiapen-2-em-3-carboxylic acid |
US4312871A (en) * | 1979-12-03 | 1982-01-26 | Merck & Co., Inc. | 6-, 1- And 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids |
EP0060077A1 (en) * | 1981-03-04 | 1982-09-15 | Beecham Group Plc | Beta-lactam antibiotics, their preparation and use |
ES514240A0 (es) * | 1981-08-03 | 1984-04-16 | Merck & Co Inc | Un procedimiento para la prepracion de nuevos derivados de acidos 2-carbamimidoil-1-,carbadestiapen-2-en-3-carboxilados. |
US4552873A (en) * | 1981-08-19 | 1985-11-12 | Sankyo Company Limited | Carbapenem compounds, and compositions containing them |
US4650794A (en) * | 1982-04-29 | 1987-03-17 | Merck & Co., Inc. | 6-(1-hydroxyethyl)-2-carbamimidoyl-pen-2-em-3-carboxylic acids |
EP0089139A2 (en) * | 1982-03-16 | 1983-09-21 | Beecham Group Plc | Antibiotics, their preparation and use |
JPS5916892A (ja) * | 1982-07-19 | 1984-01-28 | Sankyo Co Ltd | カルバペネム−3−カルボン酸誘導体およびその製法 |
JPS5951286A (ja) * | 1982-09-10 | 1984-03-24 | Sankyo Co Ltd | カルバペネム誘導体の製造法 |
EP0113101A1 (en) * | 1982-12-30 | 1984-07-11 | Merck & Co. Inc. | 6-(1-Hydroxyethyl)-2-SR8-1-methyl-1-carbadethiapen-2-em-3-carboxylic acid esters |
CA1283906C (en) * | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
JPS60104088A (ja) * | 1983-11-11 | 1985-06-08 | Sumitomo Chem Co Ltd | 新規なβ−ラクタム化合物およびその製造法 |
CH660736A5 (de) * | 1983-10-03 | 1987-06-15 | Sanraku Inc | Carbapenemderivate. |
JPS60178888A (ja) * | 1984-02-22 | 1985-09-12 | Sankyo Co Ltd | ペネムまたはカルバペネム誘導体およびその製法 |
US4696923A (en) * | 1984-04-23 | 1987-09-29 | Merck & Co., Inc. | 6-[1-hydroxyethyl]-2-SR8 -1-methyl-1-carbadethiapen-2-em-3-carboxylic acids |
DE3579888D1 (de) * | 1984-11-08 | 1990-10-31 | Sumitomo Pharma | Carbapenemverbindungen und deren herstellung. |
JPS61275279A (ja) * | 1984-12-25 | 1986-12-05 | Sankyo Co Ltd | カルバペネム化合物 |
-
1984
- 1984-03-27 JP JP59059279A patent/JPS60202886A/ja active Granted
-
1985
- 1985-03-26 AT AT85302106T patent/ATE86255T1/de not_active IP Right Cessation
- 1985-03-26 EP EP85302106A patent/EP0160391B1/en not_active Expired - Lifetime
- 1985-03-26 ZA ZA852251A patent/ZA852251B/xx unknown
- 1985-03-26 HU HU851142A patent/HU196800B/hu not_active IP Right Cessation
- 1985-03-26 DE DE85302106T patent/DE3587126T2/de not_active Expired - Fee Related
- 1985-03-26 SU SU853878791A patent/SU1501922A3/ru active
- 1985-03-27 NZ NZ211604A patent/NZ211604A/xx unknown
- 1985-03-27 FI FI851240A patent/FI83419C/fi not_active IP Right Cessation
- 1985-03-27 PH PH32061A patent/PH25057A/en unknown
- 1985-03-27 ES ES541638A patent/ES8702912A1/es not_active Expired
- 1985-03-27 DK DK138885A patent/DK169476B1/da active
- 1985-03-27 AU AU40431/85A patent/AU582148B2/en not_active Ceased
- 1985-03-27 NO NO851227A patent/NO164980C/no unknown
- 1985-03-27 KR KR1019850002037A patent/KR910010049B1/ko not_active IP Right Cessation
- 1985-03-27 IE IE77685A patent/IE59708B1/en not_active IP Right Cessation
-
1986
- 1986-01-15 ES ES550907A patent/ES8703473A1/es not_active Expired
- 1986-10-27 SU SU864028361A patent/SU1591810A3/ru active
-
1990
- 1990-01-05 US US07/463,773 patent/US5102997A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU582148B2 (en) | 1989-03-16 |
FI83419C (fi) | 1991-07-10 |
NO851227L (no) | 1985-09-30 |
DK138885A (da) | 1985-09-28 |
HU196800B (en) | 1989-01-30 |
FI851240L (fi) | 1985-09-28 |
FI851240A0 (fi) | 1985-03-27 |
US5102997A (en) | 1992-04-07 |
SU1591810A3 (ru) | 1990-09-07 |
JPH0367068B2 (da) | 1991-10-21 |
ES541638A0 (es) | 1987-01-16 |
AU4043185A (en) | 1985-10-03 |
HUT38351A (en) | 1986-05-28 |
ZA852251B (en) | 1985-12-24 |
JPS60202886A (ja) | 1985-10-14 |
SU1501922A3 (ru) | 1989-08-15 |
DK169476B1 (da) | 1994-11-07 |
FI83419B (fi) | 1991-03-28 |
EP0160391B1 (en) | 1993-03-03 |
DE3587126T2 (de) | 1993-10-07 |
IE59708B1 (en) | 1994-03-23 |
ATE86255T1 (de) | 1993-03-15 |
ES8703473A1 (es) | 1987-02-16 |
NO164980C (no) | 1990-12-05 |
NZ211604A (en) | 1989-01-06 |
PH25057A (en) | 1991-01-28 |
IE850776L (en) | 1985-09-27 |
EP0160391A1 (en) | 1985-11-06 |
ES8702912A1 (es) | 1987-01-16 |
DE3587126D1 (de) | 1993-04-08 |
KR910010049B1 (ko) | 1991-12-12 |
ES550907A0 (es) | 1987-02-16 |
NO164980B (no) | 1990-08-27 |
KR850006418A (ko) | 1985-10-05 |
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