DK155740C - Analogifremgangsmaade til fremstilling af penicillansyre-1,1-dioxid, visse estere og fysiologisk acceptable salte heraf - Google Patents

Analogifremgangsmaade til fremstilling af penicillansyre-1,1-dioxid, visse estere og fysiologisk acceptable salte heraf

Info

Publication number
DK155740C
DK155740C DK251478A DK251478A DK155740C DK 155740 C DK155740 C DK 155740C DK 251478 A DK251478 A DK 251478A DK 251478 A DK251478 A DK 251478A DK 155740 C DK155740 C DK 155740C
Authority
DK
Denmark
Prior art keywords
analogue
dioxide
preparation
acceptable salts
physiologically acceptable
Prior art date
Application number
DK251478A
Other languages
Danish (da)
English (en)
Other versions
DK251478A (da
DK155740B (da
Inventor
Wayne Ernest Barth
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27122691&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK155740(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of DK251478A publication Critical patent/DK251478A/da
Priority to DK428682A priority Critical patent/DK156480C/da
Publication of DK155740B publication Critical patent/DK155740B/da
Application granted granted Critical
Publication of DK155740C publication Critical patent/DK155740C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK251478A 1977-06-07 1978-06-06 Analogifremgangsmaade til fremstilling af penicillansyre-1,1-dioxid, visse estere og fysiologisk acceptable salte heraf DK155740C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK428682A DK156480C (da) 1977-06-07 1982-09-27 Penicillansyre-1-oxider til anvendelse som mellemprodukter ved fremstilling af terapeutisk aktive penicillansyre-1,1-dioxidderivater

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80432077A 1977-06-07 1977-06-07
US80432077 1977-06-07
US87938178A 1978-02-21 1978-02-21
US87938178 1978-02-21

Publications (3)

Publication Number Publication Date
DK251478A DK251478A (da) 1978-12-08
DK155740B DK155740B (da) 1989-05-08
DK155740C true DK155740C (da) 1989-10-23

Family

ID=27122691

Family Applications (1)

Application Number Title Priority Date Filing Date
DK251478A DK155740C (da) 1977-06-07 1978-06-06 Analogifremgangsmaade til fremstilling af penicillansyre-1,1-dioxid, visse estere og fysiologisk acceptable salte heraf

Country Status (35)

Country Link
AR (1) AR224111A1 (ko)
AT (2) AT360649B (ko)
AU (1) AU513636B2 (ko)
BE (1) BE867859A (ko)
BG (2) BG34614A3 (ko)
CH (1) CH634073A5 (ko)
CS (1) CS208472B2 (ko)
DD (2) DD148585A5 (ko)
DE (2) DE2824535C3 (ko)
DK (1) DK155740C (ko)
EG (1) EG13869A (ko)
FI (1) FI66003C (ko)
FR (2) FR2393804A1 (ko)
GB (1) GB2000138B (ko)
GR (1) GR72255B (ko)
HK (1) HK13184A (ko)
HU (1) HU180042B (ko)
IE (1) IE47079B1 (ko)
IL (2) IL54867A (ko)
IN (1) IN149747B (ko)
IT (1) IT1096381B (ko)
KE (1) KE3355A (ko)
LU (1) LU79774A1 (ko)
MY (1) MY8500092A (ko)
NL (2) NL180009C (ko)
NO (2) NO151746C (ko)
NZ (1) NZ187476A (ko)
OA (1) OA05964A (ko)
PH (3) PH26810A (ko)
PL (1) PL114501B1 (ko)
PT (1) PT68146A (ko)
SE (2) SE436206B (ko)
SG (1) SG65383G (ko)
SU (1) SU860706A1 (ko)
YU (1) YU41829B (ko)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU77306A1 (ko) * 1977-05-09 1979-01-18
DE2912511C2 (de) * 1977-06-07 1982-06-24 Pfizer Inc., 10017 New York, N.Y. Pharmazeutische Zusammensetzung, enthaltend Penicillansäure
DK155942C (da) * 1977-12-23 1989-10-23 Pfizer Analogifremgangsmaade til fremstilling af 6-aminopenicillansyre-1,1-dioxid og fysiologisk acceptable syreadditions- og basesalte deraf.
JPS54126735A (en) * 1978-03-24 1979-10-02 Toyama Chem Co Ltd Bactericidal composition for medical use
US4241050A (en) * 1978-09-01 1980-12-23 Pfizer Inc. Penam 1,1-dioxides as beta-lactamase inhibitors
CA1158639A (en) * 1978-12-11 1983-12-13 Eric M. Gordon 6-bromopenicillanic acid sulfone
IE49880B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd Penicillin derivatives
SE449103B (sv) * 1979-03-05 1987-04-06 Pfizer Sett att framstella penicillansyra-1,1-dioxid samt estrar derav
US4714761A (en) * 1979-03-05 1987-12-22 Pfizer Inc. 6,6-dihalopenicillanic acid 1,1-dioxides and process
US4420426A (en) 1979-03-05 1983-12-13 Pfizer Inc. 6-Alpha-halopenicillanic acid 1,1-dioxides
GB2045236A (en) * 1979-03-26 1980-10-29 Hoechst Uk Ltd Oxapenem derivatives
US4244951A (en) 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4309347A (en) * 1979-05-16 1982-01-05 Pfizer Inc. Penicillanoyloxymethyl penicillanate 1,1,1',1'-tetraoxide
IE49770B1 (en) * 1979-05-21 1985-12-11 Leo Pharm Prod Ltd 6beta-halopenicillanic acid derivatives
DE3051044C2 (ko) * 1979-06-19 1989-03-30 Leo Pharmaceutical Products Ltd. A/S (Loevens Kemiske Fabrik Produktionsaktieselskab), Ballerup, Dk
US4256733A (en) * 1979-09-26 1981-03-17 Pfizer Inc. Acetoxymethyl penam compounds as β-lactamase inhibitors
US4432970A (en) * 1979-11-23 1984-02-21 Pfizer Inc. 6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
IL61880A (en) * 1980-01-21 1984-11-30 Bristol Myers Co 2beta-chloromethyl-2alpha-methylpenam-3alpha-carboxylic acid sulfone derivatives,their preparation and pharmaceutical compositions containing them
US4488994A (en) * 1980-09-08 1984-12-18 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4432903A (en) * 1980-09-08 1984-02-21 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4474698A (en) * 1980-12-11 1984-10-02 Pfizer Inc. Process for preparing esters of penicillanic acid sulfone
US4419284A (en) * 1981-03-23 1983-12-06 Pfizer Inc. Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
EP0069962B1 (en) * 1981-07-15 1985-01-02 Kanebo, Ltd. Novel ester of 1,1-dioxopenicillanic acid, process for production thereof, and use thereof as beta-lactamase inhibitor
PT76526B (en) * 1982-04-19 1986-01-21 Gist Brocades Nv Preparation of 6-alpha-bromo- and/or 6,6-dibromopenicillanic acid 1,1-dioxides
US4502988A (en) * 1983-08-08 1985-03-05 Eli Lilly And Company Oxidation process
EP0139047A1 (en) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Process for the preparation of 6,6-dibromopenicillanic acid 1,1-dioxide
US4647457A (en) * 1983-12-16 1987-03-03 Hoffmann-La Roche Inc. Penicillanic acid derivatives
JPH07103129B2 (ja) * 1986-04-10 1995-11-08 レオ・ファーマシューティカル・プロダクツ・リミテッド・エイ／エス（レーベンス・ケミスケ・ファブリック・プロデュクチオンスアクチーセルスカブ） ペニシラン酸誘導体の改良された新規合成方法
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
CN102977120B (zh) * 2012-12-14 2015-05-27 江西富祥药业股份有限公司 一种舒巴坦匹酯制备及结晶方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3197466A (en) * 1961-10-30 1965-07-27 Smith Kline French Lab Penicillin sulfoxides and process
LU77306A1 (ko) * 1977-05-09 1979-01-18
AU3796278A (en) * 1977-07-13 1980-01-17 Glaxo Group Ltd Penams and azetidinones

Also Published As

Publication number Publication date
GB2000138B (en) 1982-03-03
AT360649B (de) 1981-01-26
DE2824535B2 (de) 1980-05-14
FR2393805B1 (ko) 1984-02-24
AT364084B (de) 1981-09-25
SE447995B (sv) 1987-01-12
YU41829B (en) 1988-02-29
PH16465A (en) 1983-10-20
PL114501B1 (en) 1981-02-28
DD140888A5 (de) 1980-04-02
FR2393805A1 (fr) 1979-01-05
FI781800A (fi) 1978-12-08
IL62168A0 (en) 1981-03-31
FI66003B (fi) 1984-04-30
HK13184A (en) 1984-02-24
DK251478A (da) 1978-12-08
IT1096381B (it) 1985-08-26
SE8305916L (sv) 1983-10-27
LU79774A1 (fr) 1980-01-22
AU513636B2 (en) 1980-12-11
DD148585A5 (de) 1981-06-03
GB2000138A (en) 1979-01-04
NL930064I2 (nl) 1994-04-18
NO823126L (no) 1978-12-08
CS208472B2 (en) 1981-09-15
BG34615A3 (en) 1983-10-15
IT7824270A0 (it) 1978-06-06
NL7806126A (nl) 1978-12-11
IL54867A (en) 1981-11-30
IE781140L (en) 1978-12-07
SE7806628L (sv) 1978-12-08
HU180042B (en) 1983-01-28
SE8305916D0 (sv) 1983-10-27
BG34614A3 (en) 1983-10-15
IL54867A0 (en) 1978-08-31
ATA411278A (de) 1980-06-15
NZ187476A (en) 1982-08-17
CH634073A5 (en) 1983-01-14
DE2824535C3 (de) 1981-01-22
DE2824535A1 (de) 1978-12-14
PH26810A (en) 1992-11-05
IN149747B (ko) 1982-04-03
NO781970L (no) 1978-12-08
DK155740B (da) 1989-05-08
SG65383G (en) 1985-03-29
IE47079B1 (en) 1983-12-14
FR2393804A1 (fr) 1979-01-05
NO151746C (no) 1985-06-05
ATA128580A (de) 1981-02-15
BE867859A (fr) 1978-12-06
AU3683878A (en) 1979-12-06
FR2393804B1 (ko) 1980-11-07
SU860706A1 (ru) 1981-08-30
OA05964A (fr) 1981-06-30
NO152448B (no) 1985-06-24
NO152448C (no) 1985-10-02
NO151746B (no) 1985-02-18
SE436206B (sv) 1984-11-19
DE2857263B2 (de) 1981-04-23
AR224111A1 (es) 1981-10-30
GR72255B (ko) 1983-10-06
YU117078A (en) 1983-01-21
PH21116A (en) 1987-07-16
DE2857263C3 (de) 1981-12-17
FI66003C (fi) 1984-08-10
NL180009C (nl) 1986-12-16
KE3355A (en) 1983-12-16
PT68146A (en) 1978-07-01
EG13869A (en) 1983-03-31
MY8500092A (en) 1985-12-31
NL930064I1 (nl) 1993-09-01
PL207396A1 (pl) 1979-06-04

Similar Documents

Publication Publication Date Title
DK155740C (da) Analogifremgangsmaade til fremstilling af penicillansyre-1,1-dioxid, visse estere og fysiologisk acceptable salte heraf
DK163244C (da) Analogifremgangsmaade til fremstilling af 7-oe2-(2-aminothiazol-4-yl)-2-oxyimino-acetamidoaa-ceph-3-em-4-carboxylsyrederivater eller fysiologisk acceptable salte deraf
DK149344C (da) Analogifremgangsmaade til fremstilling af 4-hydroxy-2h-1,2-benzothiazin-3-carboxamid-1,1-dioxider
DK148632C (da) Analogifremgangsmaade til fremstilling af hydroxykarbonylfosfonsyremonoestere eller optiske antipoder og/eller fysiologisk acceptable salte deraf
DK159786C (da) Analogifremgangsmaade til fremstilling af bis-estre af methandiol med penicilliner og penicillansyre-1,1-dioxid
DK159156C (da) Analogifremgangsmaade til fremstilling af (2-(2-aminothiazol-4-yl)-2-(0-substitueret)-oxyiminoacetamido)-7-cephalosporan-syre og fysiologisk acceptable salte deraf
DK160300C (da) Analogifremgangsmaade til fremstilling af substituerede phenoxybenzyloxycarbonylderivater og cyclopropancarboxylsyreestere til anvendelse som udgangsforbindelser herved
DK150472C (da) Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive cycloalkylmethylphenyleddikesyrederivater eller farmaceutisk acceptablesalte deraf
DK165455C (da) Analogifremgangsmaade til fremstilling af dipeptidderivater og farmaceutisk acceptable salte heraf
SE7813406L (sv) Forfarande for framstellning av implantat
DK152114C (da) Analogifremgangsmaade til fremstilling af propenylaminer eller farmaceutisk acceptable salte deraf
DK162444C (da) Analogifremgangsmaade til fremstilling af azabicyklooctancarboxylsyrer og farmaceutisk acceptable salte heraf
DK158836C (da) Analogifremgangsmaade til fremstilling af terapeutisk aktive anthraquinonderivater
DK155670C (da) Analogifremgangsmaade til fremstilling af sesquiterpenderivater eller farmaceutisk acceptable salte deraf
DK149625C (da) Analogifremgangsmaade til fremstilling af n-substituerede (8-halogen- eller -trifluormethyl-4-quinolylamino)-benzamider eller et farmaceutiskacceptabelt syreadditionssalt deraf
NL7800557A (nl) Benzoxa(thia)zolonderivaten en werkwijze ter bereiding daarvan.
DK152115C (da) Analogifremgangsmaade til fremstilling af fluorerede 2,5-diamino-3-pentenderivater og farmaceutisk acceptable salte deraf
DK148019C (da) Analogifremgangsmaade til fremstilling af 2-pyridylaminobenzoesyrer eller farmaceutisk acceptable salte deraf
PL209256A1 (pl) Sposob wytwarzania pochodnych kwasu 2-hydrazonopropionowego
DK164169C (da) Analogifremgangsmaade til fremstilling af 7-alfa-methoxycephalosporiner eller farmaceutisk acceptable salte deraf samt et mellemprodukt til anvendelse herved
DK150521C (da) Analogifremgangsmaade til fremstilling af n2-arylsulfonyl-l-argininamider eller farmaceutisk acceptable salte deraf
SE7800790L (sv) Sett att framstella nya oximderivat av 3-tiadiazolyl-tiometyl-7-aminotiazolyl-acetamidocefalosporansyra
DK157021C (da) Analogifremgangsmaade til fremstilling af 2,3-polymethylen-4-oxo-4h-pyrido- eller -azepinooe1,2-aaapyrimidiner eller farmaceutisk acceptable syreadditionssalte eller kvaternaere salte deraf
DK155942C (da) Analogifremgangsmaade til fremstilling af 6-aminopenicillansyre-1,1-dioxid og fysiologisk acceptable syreadditions- og basesalte deraf.
DK143273C (da) Analogifremgangsmaade til fremstilling af amidinobenzyloyrimidiner og syreadditionssalte heraf

Legal Events

Date Code Title Description
PUP Patent expired