DK151882C - Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive 5-substituerede oxazolidin-2,4-dioner eller 3-acylforbindelser eller kationsalte deraf og carboximidat-forbindelser til anvendelse som udgangsmateriale ved fremgangsmaaden - Google Patents

Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive 5-substituerede oxazolidin-2,4-dioner eller 3-acylforbindelser eller kationsalte deraf og carboximidat-forbindelser til anvendelse som udgangsmateriale ved fremgangsmaaden

Info

Publication number
DK151882C
DK151882C DK334681A DK334681A DK151882C DK 151882 C DK151882 C DK 151882C DK 334681 A DK334681 A DK 334681A DK 334681 A DK334681 A DK 334681A DK 151882 C DK151882 C DK 151882C
Authority
DK
Denmark
Prior art keywords
acyles
calated
carboximidate
diones
racemic
Prior art date
Application number
DK334681A
Other languages
Danish (da)
English (en)
Other versions
DK151882B (da
DK334681A (da
Inventor
Rodney Caughren Schnur
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK334681A publication Critical patent/DK334681A/da
Publication of DK151882B publication Critical patent/DK151882B/da
Application granted granted Critical
Publication of DK151882C publication Critical patent/DK151882C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/008—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with tri- or tetrahalomethyl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/546—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/55—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/46—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK334681A 1980-07-28 1981-07-27 Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive 5-substituerede oxazolidin-2,4-dioner eller 3-acylforbindelser eller kationsalte deraf og carboximidat-forbindelser til anvendelse som udgangsmateriale ved fremgangsmaaden DK151882C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17320680A 1980-07-28 1980-07-28
US17320680 1980-07-28
US06/222,202 US4367234A (en) 1980-07-28 1981-01-02 Hypoglycemic 5-substituted oxazolidine-2,4-diones
US22220281 1981-01-02

Publications (3)

Publication Number Publication Date
DK334681A DK334681A (da) 1982-03-05
DK151882B DK151882B (da) 1988-01-11
DK151882C true DK151882C (da) 1988-06-06

Family

ID=26868872

Family Applications (1)

Application Number Title Priority Date Filing Date
DK334681A DK151882C (da) 1980-07-28 1981-07-27 Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive 5-substituerede oxazolidin-2,4-dioner eller 3-acylforbindelser eller kationsalte deraf og carboximidat-forbindelser til anvendelse som udgangsmateriale ved fremgangsmaaden

Country Status (27)

Country Link
US (1) US4367234A (ko)
KR (3) KR850000381B1 (ko)
AR (3) AR228061A1 (ko)
AT (1) AT376424B (ko)
AU (1) AU526905B2 (ko)
CA (1) CA1155855A (ko)
CH (1) CH653025A5 (ko)
DD (1) DD202149A5 (ko)
DE (1) DE3129309A1 (ko)
DK (1) DK151882C (ko)
ES (3) ES8306367A1 (ko)
FI (1) FI77457C (ko)
FR (1) FR2487348B1 (ko)
GB (3) GB2083810B (ko)
GR (1) GR74590B (ko)
HU (1) HU185682B (ko)
IE (1) IE51427B1 (ko)
IL (1) IL63422A (ko)
IT (1) IT1138110B (ko)
LU (1) LU83512A1 (ko)
NL (1) NL8103536A (ko)
NO (1) NO812558L (ko)
NZ (1) NZ197853A (ko)
PH (1) PH17421A (ko)
PT (1) PT73437B (ko)
SE (1) SE460849B (ko)
YU (3) YU185281A (ko)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689336A (en) * 1981-01-02 1987-08-25 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine 2,4-diones
GR78120B (ko) * 1982-03-01 1984-09-26 Pfizer
US4430337A (en) * 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
JPS59186916A (ja) * 1983-04-06 1984-10-23 Aiji Noda 膵石症治療剤
US5130379A (en) * 1988-03-08 1992-07-14 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US4946942A (en) * 1988-03-11 1990-08-07 Bioresearch, Inc. Urethane-protected amino acid-N-carboxyanhydrides
US5442124A (en) * 1989-06-30 1995-08-15 Firmenich Sa Process for the preparation of novel aromatic compounds
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
CA2064815C (en) * 1990-06-07 1999-11-16 Alan Duncan Robertson Therapeutic heterocyclic compounds
GB9017218D0 (en) * 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
DE69106714T2 (de) * 1990-08-23 1995-05-11 Pfizer Hypoglykämische hydroxyharnstoffderivate.
TW222626B (ko) 1991-07-22 1994-04-21 Pfizer
US5498621A (en) * 1992-05-01 1996-03-12 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5401761A (en) * 1993-12-09 1995-03-28 Pfizer, Inc. Thiazolidinedione hypoglycemic agents
US5925656A (en) * 1995-04-10 1999-07-20 Dr. Reddy's Research Foundation Compounds having antidiabetic, hypolipidemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
GB9604242D0 (en) 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
US5801173A (en) * 1996-05-06 1998-09-01 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973850B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5889032A (en) * 1996-05-06 1999-03-30 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
BR9711098B1 (pt) * 1996-07-01 2011-10-04 compostos heterocìclicos, processo para sua preparação e composições farmacêuticas contendo os mesmos e seu uso no tratamento de diabetes e doenças relacionadas.
US6114526A (en) 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6372750B2 (en) * 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
AU743411B2 (en) * 1998-08-21 2002-01-24 Viropharma Incorporated Compounds, compositions and methods for treating or preventing viral infections and associated diseases
WO2000018745A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Oxazolidine derivatives for the treatment and prevention of metabolic bone disorders
EP1194147B1 (en) 1999-06-18 2007-01-10 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
EP1194146B1 (en) 1999-06-18 2006-07-19 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
AR065670A1 (es) 2007-03-09 2009-06-24 Indigene Pharmaceuticals Inc Combinacion de metformina r-(+) lipoato y agentes antihiperlipidemicos para el tratamiento de hiperglucemia diabetica y complicaciones diabeticas
JP5417860B2 (ja) * 2008-08-26 2014-02-19 住友化学株式会社 α−ヒドロキシエステル類の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE729852C (de) * 1939-07-06 1943-01-04 Carl Nachtigall Verfahren zur Herstellung von 2, 4-Dioxooxazolidinen
US2338220A (en) * 1942-01-31 1944-01-04 Mallinckrodt Chemical Works Process of making oxazolidinediones
US2721197A (en) * 1953-01-05 1955-10-18 Bristol Lab Inc Bicyclic lactams
US2961377A (en) * 1957-08-05 1960-11-22 Us Vitamin Pharm Corp Oral anti-diabetic compositions and methods
FR1284516A (fr) * 1957-11-20 1962-02-16 France Etat Produits utilisables notamment comme agents susceptibles d'agir sur la croissance des plantes et leur procédé de fabrication
GB1227428A (ko) * 1968-04-08 1971-04-07
US3699229A (en) * 1970-12-18 1972-10-17 Abbott Lab 2-oxo-5-phenyl-4-oxazolidinone as an anti-depressant agent
AT322266B (de) * 1972-11-06 1975-05-12 Rath Karl Friedrich Vorrichtung zum einsetzen von pflanzen
FR2207706B1 (ko) * 1972-11-24 1975-11-28 Orsymonde
DE2813873A1 (de) * 1978-03-31 1979-10-11 Basf Ag Verfahren zur herstellung von oxazolidin-2,4-dionen
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones

Also Published As

Publication number Publication date
PT73437A (en) 1981-08-01
KR850003290A (ko) 1985-06-13
KR850000387B1 (ko) 1985-03-25
KR850000382B1 (ko) 1985-03-23
IL63422A0 (en) 1981-10-30
SE8104542L (sv) 1982-01-29
ES504322A0 (es) 1983-05-16
CA1155855A (en) 1983-10-25
AU526905B2 (en) 1983-02-03
HU185682B (en) 1985-03-28
NL8103536A (nl) 1982-02-16
LU83512A1 (fr) 1982-02-17
IE51427B1 (en) 1986-12-24
AT376424B (de) 1984-11-26
AR230834A1 (es) 1984-07-31
GR74590B (ko) 1984-06-29
IT1138110B (it) 1986-09-17
IT8123175A0 (it) 1981-07-27
KR830006247A (ko) 1983-09-20
GB2132609A (en) 1984-07-11
YU88283A (en) 1983-12-31
PT73437B (en) 1983-09-01
FI77457B (fi) 1988-11-30
DK151882B (da) 1988-01-11
NO812558L (no) 1982-01-29
YU88183A (en) 1983-12-31
ATA328681A (de) 1984-04-15
GB2132609B (en) 1985-01-03
PH17421A (en) 1984-08-08
KR850003291A (ko) 1985-06-13
FR2487348B1 (fr) 1986-05-02
ES8306367A1 (es) 1983-05-16
IE811695L (en) 1982-01-28
IL63422A (en) 1984-11-30
DE3129309A1 (de) 1982-03-18
US4367234A (en) 1983-01-04
AR231721A1 (es) 1985-02-28
ES514666A0 (es) 1983-05-01
FI812340L (fi) 1982-01-29
GB8317145D0 (en) 1983-07-27
GB2128987A (en) 1984-05-10
GB8317144D0 (en) 1983-07-27
DK334681A (da) 1982-03-05
ES514665A0 (es) 1983-05-01
NZ197853A (en) 1986-09-10
FI77457C (fi) 1989-03-10
CH653025A5 (fr) 1985-12-13
FR2487348A1 (fr) 1982-01-29
YU185281A (en) 1983-12-31
ES8306133A1 (es) 1983-05-01
AR228061A1 (es) 1983-01-14
ES8306132A1 (es) 1983-05-01
KR850000381B1 (ko) 1985-03-23
SE460849B (sv) 1989-11-27
GB2083810B (en) 1984-03-14
GB2128987B (en) 1984-09-26
GB2083810A (en) 1982-03-31
DE3129309C2 (ko) 1987-06-19
DD202149A5 (de) 1983-08-31

Similar Documents

Publication Publication Date Title
DK151882C (da) Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive 5-substituerede oxazolidin-2,4-dioner eller 3-acylforbindelser eller kationsalte deraf og carboximidat-forbindelser til anvendelse som udgangsmateriale ved fremgangsmaaden
DK160936C (da) Analogifremgangsmaade til fremstilling af optisk aktive phenethanolaminer
DK153787C (da) Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved
DK159146C (da) Analogifremgangsmaade til fremstilling af 1,2-diaminocyclobuten-3,4-dioner og cyclobuten-3,4-dionderivater til anvendelse som mellemprodukter i fremgangsmaaden
DK160939C (da) Analogifremgangsmaade til fremstilling af benzisothiazol- og benzisoxazolpiperazinderivater, samt mellemprodukter til anvendelse ved fremgangsmaaden
DK148632C (da) Analogifremgangsmaade til fremstilling af hydroxykarbonylfosfonsyremonoestere eller optiske antipoder og/eller fysiologisk acceptable salte deraf
DK149850C (da) Analogifremgangsmaade til fremstilling af 5-(3,4-disubst. phenyl)-oxazolidinoner eller thiazolidinoner eller de tilsvarende thioner
DK155665C (da) Analogifremgangsmaade til fremstilling af carbostyrilforbindelser
DK163305C (da) Analogifremgangsmaade til fremstilling af 1-normon-2-yl-heterocycliske forbindelser og mellemprodukter til anvendelse ved fremgangsmaaden
DK158664C (da) Analogifremgangsmaade til fremstilling af benzoxazinoner og benzoxazolinoner samt forbindelser til anvendelse ved fremgangsmaaden.
DK334781A (da) Fremgangsmaade til fremstilling af racemiske eller optisk aktive 5-substituerede oxazolidin-2,4-dioner eller 3-acylforbindelser deraf eller salte deraf og mellemprodukter ved fremgangsmaaden
DK339680A (da) Fremgangsmaade til fremstilling af det proteolytiske enzym caldolysin ved hjaelp af mikroorganismen thermus t-351.
DK341281A (da) Fremgangsmaade til fremstilling af 3,3-dialkyldenzodiazepinderivater eller syreadditionssalte deraf samt ved fremgangsmaaden som mellemprodukter anvendelige forbindelrser
DK54880A (da) Fremgangsmaade til fremstilling af optisk aktive cephalosporin-analoge
DK160935C (da) Fremgangsmaade til fremstilling af optisk aktive alkyl-2-chlorpropionater
DK157538C (da) Analogifremgangsmaade til fremstilling af heterocycliske phenoxyaminer samt 1-cyclohexenylmethyl-pyrrolidiner til anvendelse som mellemprodukt ved fremgangsmaaden
DK152363C (da) Analogifremgangsmaade til fremstilling af 3-(omega-piperazinylalkyl)-alkylendioxybenzenderivater
DK463779A (da) Fremgangsmaade til fremstilling af en oxazol
DK591787D0 (da) Anvendelse af 5-(substitueret phenyl)-oxa-zolidinonderivater til fremstilling af et til behandling af depressioner egnet laegemiddel
DK150206C (da) Analogifremgangsmaade til fremstilling af lrf-analoge nona- eller decapeptidamider eller ikke-toksiske salte deraf og nona- eller decapeptidderivater til anvendelse som udgangsforbindelser ved fremgangsmaaden
DK161520C (da) Analogifremgangsmaade til fremstilling af penemderivater og mellemprodukter til anvendeles ved fremgangsmaaden
DK135081A (da) Fr&mgangsmaade til fremstilling af thiazoler
DK333579A (da) Analogifremgangsmaade til fremstilling af thiophencarboxamidoalkylmercaptaner
DK157865C (da) Fremgangsmaade til fremstilling af ranitidin og ethyleniminoderivat til anvendelse som udgangsmateriale ved fremgangsmaaden
DK231583D0 (da) Fremgangsmade til fremstilling af penicillin-og cephalosporinforbindelser samt forbindelser, der er anvendelige som mellemprodukter ved en sadan fremgangsmade