DK163305C - Analogifremgangsmaade til fremstilling af 1-normon-2-yl-heterocycliske forbindelser og mellemprodukter til anvendelse ved fremgangsmaaden - Google Patents
Analogifremgangsmaade til fremstilling af 1-normon-2-yl-heterocycliske forbindelser og mellemprodukter til anvendelse ved fremgangsmaadenInfo
- Publication number
- DK163305C DK163305C DK095483A DK95483A DK163305C DK 163305 C DK163305 C DK 163305C DK 095483 A DK095483 A DK 095483A DK 95483 A DK95483 A DK 95483A DK 163305 C DK163305 C DK 163305C
- Authority
- DK
- Denmark
- Prior art keywords
- normon
- analogy
- intermediates
- procedure
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/653—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8205842 | 1982-02-27 | ||
| GB8205842 | 1982-02-27 | ||
| GB8230800 | 1982-10-28 | ||
| GB8230800 | 1982-10-28 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK95483D0 DK95483D0 (da) | 1983-02-25 |
| DK95483A DK95483A (da) | 1983-08-28 |
| DK163305B DK163305B (da) | 1992-02-17 |
| DK163305C true DK163305C (da) | 1992-08-03 |
Family
ID=26282099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK095483A DK163305C (da) | 1982-02-27 | 1983-02-25 | Analogifremgangsmaade til fremstilling af 1-normon-2-yl-heterocycliske forbindelser og mellemprodukter til anvendelse ved fremgangsmaaden |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US4812470A (da) |
| EP (1) | EP0087953B1 (da) |
| JP (1) | JPH064627B2 (da) |
| AU (1) | AU563067B2 (da) |
| CA (1) | CA1195983A (da) |
| DE (1) | DE3376424D1 (da) |
| DK (1) | DK163305C (da) |
| ES (2) | ES520132A0 (da) |
| HK (1) | HK47091A (da) |
| IE (1) | IE55221B1 (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK163305C (da) * | 1982-02-27 | 1992-08-03 | Beecham Group Plc | Analogifremgangsmaade til fremstilling af 1-normon-2-yl-heterocycliske forbindelser og mellemprodukter til anvendelse ved fremgangsmaaden |
| GB8305316D0 (en) * | 1983-02-25 | 1983-03-30 | Beecham Group Plc | Compounds |
| DE3736113A1 (de) * | 1987-10-26 | 1989-05-03 | Hoechst Ag | Arzneimittel, darin enthaltene phosphorhaltige 2-isoxazoline und isoxazole, sowie herstellungsverfahren fuer diese heterocyclischen verbindungen |
| GB8815626D0 (en) * | 1988-06-30 | 1988-08-03 | Beecham Group Plc | Novel compounds |
| IL94051A0 (en) * | 1989-04-12 | 1991-01-31 | Beecham Group Plc | 1-normon-2-yl-heterocycles,process for their preparation and pharmaceutical compositions containing them |
| GB8928839D0 (en) * | 1989-12-21 | 1990-02-28 | Beecham Group Plc | Novel compounds |
| DE4126994A1 (de) * | 1991-08-16 | 1993-02-18 | Basf Ag | (alpha)-arylacrylsaeurederivate, ihre herstellung und verwendung zur bekaempfung von schaedlingen und pilzen |
| GB9201391D0 (en) * | 1992-01-22 | 1992-03-11 | Smithkline Beecham Plc | Method of treatment |
| GB9207214D0 (en) * | 1992-04-02 | 1992-05-13 | Smithkline Beecham Plc | Novel compounds |
| US5380738A (en) * | 1993-05-21 | 1995-01-10 | Monsanto Company | 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents |
| AU7497594A (en) * | 1993-08-13 | 1995-03-14 | Smithkline Beecham Plc | Derivatives of monic acids a and c having antibacterial, antimycoplasmatical, antifungal and herbicidal activity |
| AU6500696A (en) * | 1995-07-28 | 1997-02-26 | Cubist Pharmaceuticals, Inc. | Aminoacyl adenylate mimics as novel antimicrobial and antiparasitic agents |
| US5726195A (en) * | 1995-07-28 | 1998-03-10 | Cubist Pharmaceuticals, Inc. | Aminoacyl adenylate mimics as novel antimicrobial and antiparasitic agents |
| AU1209497A (en) * | 1995-12-27 | 1997-07-28 | Takeda Chemical Industries Ltd. | Oxazole derivatives, their production and use |
| ES2226839T3 (es) | 1999-05-05 | 2005-04-01 | MERCK & CO., INC. | Nuevos catecoles como agentes antimicrobianos. |
| DE60026514T2 (de) | 1999-05-05 | 2006-11-09 | Merck & Co., Inc. | Neue prolinverbindungen als mikrobizide mittel |
| EP2295444A3 (en) | 1999-12-15 | 2011-03-23 | Cubist Pharmaceutical Inc. | Lipopeptides as antibacterial agents |
| US6696412B1 (en) | 2000-01-20 | 2004-02-24 | Cubist Pharmaceuticals, Inc. | High purity lipopeptides, Lipopeptide micelles and processes for preparing same |
| IL156394A0 (en) | 2000-12-18 | 2004-01-04 | Cubist Pharm Inc | Methods for preparing purified lipopeptides |
| EP1932853A1 (en) | 2001-08-06 | 2008-06-18 | Cubist Pharmaceutical Inc. | Novel depsipeptides and process for preparing same |
| IL150907A (en) * | 2002-07-25 | 2007-07-04 | Stephan Cherkez | Process for the preparation of stable amorphous calcium pseudomonate |
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| US20080051326A1 (en) * | 2004-11-12 | 2008-02-28 | Alexander Dylan C | Antiinfective Lipopeptides |
| GB2459509B (en) * | 2008-04-25 | 2011-05-11 | Goodwin Plc | An apparatus for casting and a method of casting |
| CN102325787B (zh) | 2008-12-22 | 2014-05-28 | 丘比斯特药物股份有限公司 | 治疗革兰氏阳性感染的新的抗菌剂 |
| WO2010075416A1 (en) | 2008-12-23 | 2010-07-01 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2012029032A2 (en) | 2010-09-03 | 2012-03-08 | Piramal Life Sciences Limited | Heterocyclic compounds as dgat1 inhibitors |
| CN104334558A (zh) | 2012-03-30 | 2015-02-04 | 丘比斯特药物股份有限公司 | 1,3,4-噁二唑和1,3,4-噻二唑β-内酰胺酶抑制剂 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2860726D1 (en) * | 1977-11-05 | 1981-08-27 | Beecham Group Plc | Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides |
| DK163305C (da) * | 1982-02-27 | 1992-08-03 | Beecham Group Plc | Analogifremgangsmaade til fremstilling af 1-normon-2-yl-heterocycliske forbindelser og mellemprodukter til anvendelse ved fremgangsmaaden |
-
1983
- 1983-02-25 DK DK095483A patent/DK163305C/da not_active IP Right Cessation
- 1983-02-25 DE DE8383301022T patent/DE3376424D1/de not_active Expired
- 1983-02-25 EP EP83301022A patent/EP0087953B1/en not_active Expired
- 1983-02-25 US US06/469,819 patent/US4812470A/en not_active Expired - Fee Related
- 1983-02-25 ES ES520132A patent/ES520132A0/es active Granted
- 1983-02-25 IE IE403/83A patent/IE55221B1/en not_active IP Right Cessation
- 1983-02-25 AU AU11853/83A patent/AU563067B2/en not_active Ceased
- 1983-02-25 CA CA000422461A patent/CA1195983A/en not_active Expired
- 1983-02-26 JP JP58031707A patent/JPH064627B2/ja not_active Expired - Lifetime
- 1983-10-06 ES ES526295A patent/ES8704483A1/es not_active Expired
-
1988
- 1988-11-28 US US07/276,910 patent/US5041567A/en not_active Expired - Fee Related
-
1991
- 1991-06-11 HK HK470/91A patent/HK47091A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES526295A0 (es) | 1987-04-01 |
| EP0087953B1 (en) | 1988-04-27 |
| IE830403L (en) | 1983-08-27 |
| AU563067B2 (en) | 1987-06-25 |
| EP0087953A2 (en) | 1983-09-07 |
| IE55221B1 (en) | 1990-07-04 |
| HK47091A (en) | 1991-06-21 |
| AU1185383A (en) | 1983-09-01 |
| DE3376424D1 (en) | 1988-06-01 |
| JPH064627B2 (ja) | 1994-01-19 |
| CA1195983A (en) | 1985-10-29 |
| US4812470A (en) | 1989-03-14 |
| ES8403890A1 (es) | 1984-04-01 |
| ES8704483A1 (es) | 1987-04-01 |
| DK95483D0 (da) | 1983-02-25 |
| DK163305B (da) | 1992-02-17 |
| ES520132A0 (es) | 1984-04-01 |
| JPS58159491A (ja) | 1983-09-21 |
| DK95483A (da) | 1983-08-28 |
| US5041567A (en) | 1991-08-20 |
| EP0087953A3 (en) | 1984-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |