DK54880A - Fremgangsmaade til fremstilling af optisk aktive cephalosporin-analoge - Google Patents

Fremgangsmaade til fremstilling af optisk aktive cephalosporin-analoge

Info

Publication number
DK54880A
DK54880A DK54880A DK54880A DK54880A DK 54880 A DK54880 A DK 54880A DK 54880 A DK54880 A DK 54880A DK 54880 A DK54880 A DK 54880A DK 54880 A DK54880 A DK 54880A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
optically active
active cephalosporin
analogue
Prior art date
Application number
DK54880A
Other languages
English (en)
Other versions
DK170255B1 (da
Inventor
T Hirata
Y Hashimoto
T Ogasa
S Kobayashi
I Matsukuma
K Kimura
S Yoshiie
K Sato
Y Ohashi
S Takasawa
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1453479A external-priority patent/JPS55108877A/ja
Priority claimed from JP4589779A external-priority patent/JPS55138396A/ja
Priority claimed from JP9203579A external-priority patent/JPS5616491A/ja
Priority claimed from JP14047679A external-priority patent/JPS5664795A/ja
Priority claimed from JP14648979A external-priority patent/JPS5672698A/ja
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of DK54880A publication Critical patent/DK54880A/da
Application granted granted Critical
Publication of DK170255B1 publication Critical patent/DK170255B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK054880A 1979-02-10 1980-02-08 Analogifremgangsmåde til fremstilling af optisk aktive cephalosporin-analoge DK170255B1 (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP1453479A JPS55108877A (en) 1979-02-10 1979-02-10 Optically active cephalosporin analog
JP1453479 1979-02-10
JP4589779A JPS55138396A (en) 1979-04-14 1979-04-14 Production of cephalosporin analogs
JP4589779 1979-04-14
JP9203579A JPS5616491A (en) 1979-07-19 1979-07-19 Cephalosporin analog
JP9203579 1979-07-19
JP14047679A JPS5664795A (en) 1979-11-01 1979-11-01 Preparation of cephalosporin analog
JP14047679 1979-11-01
JP14648979 1979-11-14
JP14648979A JPS5672698A (en) 1979-11-14 1979-11-14 Preparation of optically active cephalosporin analogue

Publications (2)

Publication Number Publication Date
DK54880A true DK54880A (da) 1980-08-11
DK170255B1 DK170255B1 (da) 1995-07-17

Family

ID=27519617

Family Applications (1)

Application Number Title Priority Date Filing Date
DK054880A DK170255B1 (da) 1979-02-10 1980-02-08 Analogifremgangsmåde til fremstilling af optisk aktive cephalosporin-analoge

Country Status (6)

Country Link
EP (1) EP0014476B1 (da)
AU (1) AU5538280A (da)
CA (1) CA1171373A (da)
DE (1) DE3064509D1 (da)
DK (1) DK170255B1 (da)
NO (2) NO155548C (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5671092A (en) * 1979-11-14 1981-06-13 Kyowa Hakko Kogyo Co Ltd Optical active cephalosporin analogous derivative
US4347183A (en) * 1981-02-02 1982-08-31 Schering Corporation Process for the synthesis of penems and carbapenems
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
EP0112481A1 (en) * 1982-11-12 1984-07-04 Kyowa Hakko Kogyo Co., Ltd Beta-lactam compound
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd 3位置換カルバセフエム化合物
US4673737A (en) 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof
US4708956A (en) * 1985-12-12 1987-11-24 Kyowa Hakko Kogyo Co., Ltd. 3-position halogenated cephalosporin analogs and pharmaceutical compositions
JPH0791291B2 (ja) * 1985-12-30 1995-10-04 イ−ライ・リリ−・アンド・カンパニ− 1−カルバセフアロスポリン抗生物質
ATE79119T1 (de) * 1986-10-03 1992-08-15 Lilly Co Eli 7-((meta-substituiert)-phenylglycin>-1-carba-1dethia-cephalosporine.
US4885291A (en) * 1988-01-14 1989-12-05 Eli Lilly And Company 1-carba(dethia)-3-cephem derivatives
DE3803169A1 (de) 1988-02-03 1989-08-17 Bayer Ag Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln
ZA89829B (en) * 1988-02-05 1990-10-31 Lilly Co Eli Crystalline b-lactam solvate
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic
CA2034592C (en) * 1990-01-26 2001-06-05 Ralph R. Pfeiffer Crystalline hydrochloride of new beta-lactam antibiotic and process therefor
CS133392A3 (en) * 1991-05-10 1992-11-18 Lilly Co Eli Process for preparing twice blocked1-carba(1-dithia)-3-cephem-4-carboxylic acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
NO790956L (no) * 1978-03-25 1979-09-26 Kyowa Hakko Kogyo Kk Analogifremgangsmaate til fremstilling av cefalosporinanaloge eller farmasoeytisk akseptable salter derav

Also Published As

Publication number Publication date
NO841499L (no) 1980-08-11
NO155548B (no) 1987-01-05
EP0014476B1 (en) 1983-08-10
NO800315L (no) 1980-08-11
CA1171373A (en) 1984-07-24
NO155548C (no) 1987-04-15
DK170255B1 (da) 1995-07-17
AU5538280A (en) 1980-08-14
DE3064509D1 (en) 1983-09-15
EP0014476A1 (en) 1980-08-20

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1995 00013, 950807

CTFG Supplementary protection certificate (spc) issued

Free format text: CA 1995 00013, 950807, EXPIRES: 20050208

PUP Patent expired