DK394080A - Fremgangsmaade til fremstilling af carbostyrilderivater - Google Patents
Fremgangsmaade til fremstilling af carbostyrilderivaterInfo
- Publication number
- DK394080A DK394080A DK394080A DK394080A DK394080A DK 394080 A DK394080 A DK 394080A DK 394080 A DK394080 A DK 394080A DK 394080 A DK394080 A DK 394080A DK 394080 A DK394080 A DK 394080A
- Authority
- DK
- Denmark
- Prior art keywords
- carbostyric
- derivatives
- procedure
- preparation
- carbostyric derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12045279A JPS5643280A (en) | 1979-09-18 | 1979-09-18 | Carbostyril derivative |
| JP12045279 | 1979-09-18 | ||
| JP12556579 | 1979-09-28 | ||
| JP12556579A JPS5649360A (en) | 1979-09-28 | 1979-09-28 | 2-oxoquinoline derivative |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK394080A true DK394080A (da) | 1981-03-19 |
| DK158984B DK158984B (da) | 1990-08-13 |
| DK158984C DK158984C (da) | 1991-01-14 |
Family
ID=26458032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK394080A DK158984C (da) | 1979-09-18 | 1980-09-17 | Analogifremgangsmaade til fremstilling af carbostyrilderivater |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4482560A (da) |
| AR (2) | AR230280A1 (da) |
| AT (1) | AT376972B (da) |
| AU (1) | AU518144B2 (da) |
| CA (1) | CA1151172A (da) |
| CH (1) | CH645892A5 (da) |
| DE (1) | DE3034237A1 (da) |
| DK (1) | DK158984C (da) |
| ES (1) | ES8200679A1 (da) |
| FI (1) | FI76322C (da) |
| FR (1) | FR2465732A1 (da) |
| GB (1) | GB2063869B (da) |
| IT (1) | IT1129263B (da) |
| MX (1) | MX6806E (da) |
| NL (1) | NL187912C (da) |
| NO (1) | NO154841C (da) |
| PT (1) | PT71810B (da) |
| SE (1) | SE439632B (da) |
| SU (1) | SU1091857A3 (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2901336A1 (de) | 1979-01-15 | 1980-07-24 | Boehringer Mannheim Gmbh | Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| CH655110A5 (de) * | 1982-09-03 | 1986-03-27 | Otsuka Pharma Co Ltd | Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten. |
| GB8426584D0 (en) * | 1984-10-19 | 1984-11-28 | Beecham Group Plc | Compounds |
| US4704390A (en) * | 1986-02-13 | 1987-11-03 | Warner-Lambert Company | Phenyl and heterocyclic tetrahydropyridyl alkoxy-benzheterocyclic compounds as antipsychotic agents |
| US4792561A (en) * | 1986-05-29 | 1988-12-20 | Syntex (U.S.A.) Inc. | Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors |
| US4921862A (en) * | 1986-05-29 | 1990-05-01 | Syntex (U.S.A.) Inc. | Carbostyril derivatives as combined thromboxane synthetase and cyclic-amp phosphodiesterase inhibitors |
| US4886809A (en) * | 1986-07-31 | 1989-12-12 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof |
| FR2620704B1 (fr) * | 1987-09-17 | 1991-04-26 | Sanofi Sa | Derives de (benzyl-4 piperidino)-1 propanol-2, leur preparation, leur utilisation comme antimicrobiens et les produits les contenant |
| US5227381A (en) * | 1988-05-02 | 1993-07-13 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative |
| US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
| JP2686887B2 (ja) * | 1992-08-11 | 1997-12-08 | キッセイ薬品工業株式会社 | ピペリジノ−３，４−ジヒドロカルボスチリル誘導体 |
| IT1264816B1 (it) * | 1993-07-28 | 1996-10-10 | Pergam Srl | Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile |
| ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| ZA9610736B (en) | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
| US7229986B2 (en) | 2000-05-16 | 2007-06-12 | Takeda Pharmaceutical Company Ltd. | Melanin-concentrating hormone antagonist |
| ES2250919T5 (es) † | 2003-01-09 | 2010-12-03 | Otsuka Pharmaceutical Co., Ltd. | Procedimiento de preparación de aripiprazol. |
| DE102008022221A1 (de) | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
| US8541404B2 (en) | 2009-11-09 | 2013-09-24 | Elexopharm Gmbh | Inhibitors of the human aldosterone synthase CYP11B2 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3629266A (en) * | 1969-03-03 | 1971-12-21 | Miles Lab | (phenyl piperidino alkyl)3 4-dihydrocarbostyrils |
| JPS48103590A (da) * | 1972-04-13 | 1973-12-25 | ||
| US3910924A (en) * | 1972-04-13 | 1975-10-07 | Otsuka Pharma Co Ltd | 3,4-Dihydrocarbostyril derivatives and a process for preparing the same |
| US4256890A (en) * | 1972-09-14 | 1981-03-17 | Otsukapharmaceutical Co., Ltd. | 3,4-Dihydrocarbostyril derivatives and process for producing the same |
| JPS5239035B2 (da) * | 1972-12-14 | 1977-10-03 | ||
| JPS5310986B2 (da) * | 1974-02-05 | 1978-04-18 | ||
| JPS5310989B2 (da) * | 1974-04-25 | 1978-04-18 | ||
| US3994900A (en) * | 1976-01-23 | 1976-11-30 | E. R. Squibb & Sons, Inc. | 6-(Or 8)-[[(substituted amino)alkyl]oxy(or thio)]-3,4-dihydro-4-phenyl-2(1H)-quinolinones |
| JPS609501B2 (ja) * | 1976-05-07 | 1985-03-11 | 大塚製薬株式会社 | 新規３，４−ジヒドロカルボスチリル誘導体 |
| US4210753A (en) * | 1976-03-17 | 1980-07-01 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril compounds |
| JPS5919541B2 (ja) * | 1976-03-17 | 1984-05-07 | 大塚製薬株式会社 | 新規３，４−ジヒドロカルボスチリル誘導体 |
| CH619453A5 (da) * | 1976-03-17 | 1980-09-30 | Otsuka Pharma Co Ltd | |
| GB1574665A (en) * | 1976-05-08 | 1980-09-10 | Otsuka Pharma Co Ltd | 3,4-dihydrocarbostyril derivatives and process for preparing the same |
| JPS6019295B2 (ja) * | 1977-03-04 | 1985-05-15 | 大塚製薬株式会社 | カルボスチリル誘導体及びその製造法 |
| JPS5416478A (en) * | 1977-07-08 | 1979-02-07 | Otsuka Pharmaceut Co Ltd | 3,4-dihydrocarbostyril herivative |
| JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| DE2827566A1 (de) * | 1978-06-23 | 1980-01-10 | Boehringer Mannheim Gmbh | 1,2-dihydro-chinolin-2-on-derivate und verfahren zu ihrer herstellung |
| JPS5589222A (en) * | 1978-12-28 | 1980-07-05 | Otsuka Pharmaceut Co Ltd | Antihistaminic agent |
| JPS5589221A (en) * | 1978-12-28 | 1980-07-05 | Otsuka Pharmaceut Co Ltd | Antihistaminic agent |
| DE2901336A1 (de) * | 1979-01-15 | 1980-07-24 | Boehringer Mannheim Gmbh | Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
-
1980
- 1980-09-11 DE DE19803034237 patent/DE3034237A1/de active Granted
- 1980-09-12 AU AU62381/80A patent/AU518144B2/en not_active Ceased
- 1980-09-12 FR FR8019708A patent/FR2465732A1/fr active Granted
- 1980-09-16 SU SU802982853A patent/SU1091857A3/ru active
- 1980-09-16 FI FI802905A patent/FI76322C/fi not_active IP Right Cessation
- 1980-09-17 AR AR282565A patent/AR230280A1/es active
- 1980-09-17 CH CH694080A patent/CH645892A5/de not_active IP Right Cessation
- 1980-09-17 CA CA000360402A patent/CA1151172A/en not_active Expired
- 1980-09-17 NL NLAANVRAGE8005188,A patent/NL187912C/xx not_active IP Right Cessation
- 1980-09-17 NO NO802762A patent/NO154841C/no unknown
- 1980-09-17 PT PT71810A patent/PT71810B/pt unknown
- 1980-09-17 DK DK394080A patent/DK158984C/da active
- 1980-09-17 SE SE8006498A patent/SE439632B/sv not_active IP Right Cessation
- 1980-09-17 AT AT0465780A patent/AT376972B/de not_active IP Right Cessation
- 1980-09-18 IT IT68445/80A patent/IT1129263B/it active
- 1980-09-18 ES ES495163A patent/ES8200679A1/es not_active Expired
- 1980-09-18 GB GB8030207A patent/GB2063869B/en not_active Expired
- 1980-09-18 MX MX809034U patent/MX6806E/es unknown
-
1982
- 1982-03-12 US US06/357,769 patent/US4482560A/en not_active Expired - Fee Related
- 1982-05-18 AR AR289431A patent/AR230059A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| SE439632B (sv) | 1985-06-24 |
| NO154841C (no) | 1987-01-07 |
| DE3034237C2 (da) | 1988-04-21 |
| MX6806E (es) | 1986-07-30 |
| ES495163A0 (es) | 1981-11-16 |
| SE8006498L (sv) | 1981-03-19 |
| FI76322B (fi) | 1988-06-30 |
| DK158984C (da) | 1991-01-14 |
| AT376972B (de) | 1985-01-25 |
| AR230059A1 (es) | 1984-02-29 |
| NL187912C (nl) | 1992-02-17 |
| DE3034237A1 (de) | 1981-04-16 |
| NO154841B (no) | 1986-09-22 |
| IT1129263B (it) | 1986-06-04 |
| FI802905A (fi) | 1981-03-19 |
| CA1151172A (en) | 1983-08-02 |
| SU1091857A3 (ru) | 1984-05-07 |
| AU6238180A (en) | 1981-05-28 |
| NL187912B (nl) | 1991-09-16 |
| NO802762L (no) | 1981-03-19 |
| GB2063869A (en) | 1981-06-10 |
| NL8005188A (nl) | 1981-03-20 |
| FI76322C (fi) | 1988-10-10 |
| US4482560A (en) | 1984-11-13 |
| ATA465780A (de) | 1984-06-15 |
| AU518144B2 (en) | 1981-09-17 |
| PT71810B (en) | 1981-07-07 |
| FR2465732A1 (fr) | 1981-03-27 |
| ES8200679A1 (es) | 1981-11-16 |
| CH645892A5 (de) | 1984-10-31 |
| IT8068445A0 (it) | 1980-09-18 |
| PT71810A (en) | 1980-10-01 |
| GB2063869B (en) | 1983-05-25 |
| AR230280A1 (es) | 1984-03-01 |
| DK158984B (da) | 1990-08-13 |
| FR2465732B1 (da) | 1983-06-24 |
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