CH619453A5 - - Google Patents

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Publication number
CH619453A5
CH619453A5 CH308777A CH308777A CH619453A5 CH 619453 A5 CH619453 A5 CH 619453A5 CH 308777 A CH308777 A CH 308777A CH 308777 A CH308777 A CH 308777A CH 619453 A5 CH619453 A5 CH 619453A5
Authority
CH
Switzerland
Prior art keywords
group
dihydrocarbostyrile
hydroxypropoxy
hydroxy
formula
Prior art date
Application number
CH308777A
Other languages
English (en)
French (fr)
Inventor
Michiaki Tominaga
Hitoshi Tone
Kazuyuki Nadagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP51028957A external-priority patent/JPS5919541B2/ja
Priority claimed from JP51052498A external-priority patent/JPS609501B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of CH619453A5 publication Critical patent/CH619453A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
CH308777A 1976-03-17 1977-03-11 CH619453A5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP51028957A JPS5919541B2 (ja) 1976-03-17 1976-03-17 新規３，４−ジヒドロカルボスチリル誘導体
JP51052498A JPS609501B2 (ja) 1976-05-07 1976-05-07 新規３，４−ジヒドロカルボスチリル誘導体

Publications (1)

Publication Number Publication Date
CH619453A5 true CH619453A5 (da) 1980-09-30

Family

ID=26367107

Family Applications (1)

Application Number Title Priority Date Filing Date
CH308777A CH619453A5 (da) 1976-03-17 1977-03-11

Country Status (20)

Country Link
US (2) US4302588A (da)
AR (1) AR211570A1 (da)
AT (1) AT363474B (da)
AU (1) AU513950B2 (da)
CA (1) CA1081232A (da)
CH (1) CH619453A5 (da)
DE (1) DE2711719C2 (da)
DK (1) DK154970C (da)
ES (1) ES456963A1 (da)
FI (1) FI63224C (da)
FR (1) FR2344538A1 (da)
GB (2) GB1578972A (da)
IE (1) IE45269B1 (da)
LU (1) LU76957A1 (da)
MX (1) MX4808E (da)
NL (1) NL179816C (da)
NO (1) NO149388C (da)
PH (1) PH15115A (da)
PT (1) PT66312B (da)
SE (1) SE443140B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
AU518814B2 (en) * 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
FR2539413A1 (fr) * 1983-01-17 1984-07-20 Pos Lab Carbostyriloximinopropanolamines utiles comme medicaments et procede pour leur preparation
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
EA002984B1 (ru) * 1996-04-09 2002-12-26 Эн Пи Эс Фармасьютикалз, Инк. Кальцилитические соединения, фармацевтические композиции и способ скрининга кальцилитических соединений
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds
TW483881B (en) 1996-12-03 2002-04-21 Nps Pharma Inc Calcilytic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS517672B2 (da) * 1972-04-13 1976-03-10
US3910924A (en) * 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
JPS5239035B2 (da) * 1972-12-14 1977-10-03
US3975391A (en) * 1973-12-26 1976-08-17 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
JPS5082218A (da) * 1973-11-10 1975-07-03
DK138890C (da) * 1973-12-26 1979-04-30 Otsuka Pharma Co Ltd Analogifremgangsmaade til fremstilling af et carbostyril- eller 3,4-dihydrocarbostyrilderivat eller syreadditionssalte deraf
US4022776A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives
US3994901A (en) * 1974-06-13 1976-11-30 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
FI58329C (fi) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds

Also Published As

Publication number Publication date
SE7703000L (sv) 1977-09-18
PH15115A (en) 1982-08-10
DK154970B (da) 1989-01-16
AT363474B (de) 1981-08-10
DE2711719A1 (de) 1977-09-22
IE45269L (en) 1977-09-17
GB1578972A (en) 1980-11-12
IE45269B1 (en) 1982-07-28
AU2329977A (en) 1978-09-28
SE443140B (sv) 1986-02-17
PT66312B (en) 1978-08-11
AU513950B2 (en) 1981-01-15
FR2344538B1 (da) 1980-07-18
FR2344538A1 (fr) 1977-10-14
NO149388C (no) 1984-04-11
DE2711719C2 (de) 1985-02-14
FI63224C (fi) 1983-05-10
PT66312A (en) 1977-04-01
NL179816C (nl) 1986-11-17
DK115677A (da) 1977-09-18
ES456963A1 (es) 1978-07-16
NO770940L (no) 1977-09-20
AR211570A1 (es) 1978-01-30
US4289883A (en) 1981-09-15
GB1578971A (en) 1980-11-12
ATA181577A (de) 1981-01-15
NL179816B (nl) 1986-06-16
NL7702896A (nl) 1977-09-20
NO149388B (no) 1984-01-02
DK154970C (da) 1989-06-12
MX4808E (es) 1982-10-14
FI63224B (fi) 1983-01-31
LU76957A1 (da) 1977-07-15
CA1081232A (en) 1980-07-08
FI770827A (da) 1977-09-18
US4302588A (en) 1981-11-24

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Legal Events

Date Code Title Description
PL Patent ceased