FI63224C - Foerfarande foer framstaellning av medicinskt anvaendbara 5-(3-amino-2-hydroxipropoxi)-karbostyrilderivat - Google Patents

Foerfarande foer framstaellning av medicinskt anvaendbara 5-(3-amino-2-hydroxipropoxi)-karbostyrilderivat Download PDF

Info

Publication number
FI63224C
FI63224C FI770827A FI770827A FI63224C FI 63224 C FI63224 C FI 63224C FI 770827 A FI770827 A FI 770827A FI 770827 A FI770827 A FI 770827A FI 63224 C FI63224 C FI 63224C
Authority
FI
Finland
Prior art keywords
group
alkyl
carbon atoms
cholatomers
moiety
Prior art date
Application number
FI770827A
Other languages
English (en)
Finnish (fi)
Other versions
FI770827A (da
FI63224B (fi
Inventor
Michiaki Tominaga
Hitoshi Tone
Kazuyuki Nakagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP51028957A external-priority patent/JPS5919541B2/ja
Priority claimed from JP51052498A external-priority patent/JPS609501B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of FI770827A publication Critical patent/FI770827A/fi
Publication of FI63224B publication Critical patent/FI63224B/fi
Application granted granted Critical
Publication of FI63224C publication Critical patent/FI63224C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
FI770827A 1976-03-17 1977-03-15 Foerfarande foer framstaellning av medicinskt anvaendbara 5-(3-amino-2-hydroxipropoxi)-karbostyrilderivat FI63224C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2895776 1976-03-17
JP51028957A JPS5919541B2 (ja) 1976-03-17 1976-03-17 新規３，４−ジヒドロカルボスチリル誘導体
JP51052498A JPS609501B2 (ja) 1976-05-07 1976-05-07 新規３，４−ジヒドロカルボスチリル誘導体
JP5249876 1976-05-07

Publications (3)

Publication Number Publication Date
FI770827A FI770827A (da) 1977-09-18
FI63224B FI63224B (fi) 1983-01-31
FI63224C true FI63224C (fi) 1983-05-10

Family

ID=26367107

Family Applications (1)

Application Number Title Priority Date Filing Date
FI770827A FI63224C (fi) 1976-03-17 1977-03-15 Foerfarande foer framstaellning av medicinskt anvaendbara 5-(3-amino-2-hydroxipropoxi)-karbostyrilderivat

Country Status (20)

Country Link
US (2) US4289883A (da)
AR (1) AR211570A1 (da)
AT (1) AT363474B (da)
AU (1) AU513950B2 (da)
CA (1) CA1081232A (da)
CH (1) CH619453A5 (da)
DE (1) DE2711719C2 (da)
DK (1) DK154970C (da)
ES (1) ES456963A1 (da)
FI (1) FI63224C (da)
FR (1) FR2344538A1 (da)
GB (2) GB1578971A (da)
IE (1) IE45269B1 (da)
LU (1) LU76957A1 (da)
MX (1) MX4808E (da)
NL (1) NL179816C (da)
NO (1) NO149388C (da)
PH (1) PH15115A (da)
PT (1) PT66312B (da)
SE (1) SE443140B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
AU518814B2 (en) * 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
FR2539413A1 (fr) * 1983-01-17 1984-07-20 Pos Lab Carbostyriloximinopropanolamines utiles comme medicaments et procede pour leur preparation
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
SG99290A1 (en) * 1996-04-09 2003-10-27 Nps Pharma Inc Calcilytic compounds
TW483881B (en) 1996-12-03 2002-04-21 Nps Pharma Inc Calcilytic compounds
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS517672B2 (da) * 1972-04-13 1976-03-10
US3910924A (en) * 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
JPS5239035B2 (da) * 1972-12-14 1977-10-03
US3975391A (en) * 1973-12-26 1976-08-17 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
JPS5082218A (da) * 1973-11-10 1975-07-03
DK138890C (da) * 1973-12-26 1979-04-30 Otsuka Pharma Co Ltd Analogifremgangsmaade til fremstilling af et carbostyril- eller 3,4-dihydrocarbostyrilderivat eller syreadditionssalte deraf
US4026897A (en) * 1974-01-31 1977-05-31 Otsuka Pharmaceutical Company 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxycarbostyril derivatives
US3994901A (en) * 1974-06-13 1976-11-30 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
FI58329C (fi) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds

Also Published As

Publication number Publication date
AR211570A1 (es) 1978-01-30
CA1081232A (en) 1980-07-08
FI770827A (da) 1977-09-18
GB1578971A (en) 1980-11-12
NO149388C (no) 1984-04-11
AU2329977A (en) 1978-09-28
NL179816B (nl) 1986-06-16
NO770940L (no) 1977-09-20
US4289883A (en) 1981-09-15
PT66312A (en) 1977-04-01
IE45269L (en) 1977-09-17
FR2344538B1 (da) 1980-07-18
PH15115A (en) 1982-08-10
CH619453A5 (da) 1980-09-30
DE2711719A1 (de) 1977-09-22
DK154970C (da) 1989-06-12
DK154970B (da) 1989-01-16
ATA181577A (de) 1981-01-15
NL7702896A (nl) 1977-09-20
AU513950B2 (en) 1981-01-15
AT363474B (de) 1981-08-10
PT66312B (en) 1978-08-11
FR2344538A1 (fr) 1977-10-14
DK115677A (da) 1977-09-18
NL179816C (nl) 1986-11-17
GB1578972A (en) 1980-11-12
IE45269B1 (en) 1982-07-28
NO149388B (no) 1984-01-02
ES456963A1 (es) 1978-07-16
DE2711719C2 (de) 1985-02-14
SE7703000L (sv) 1977-09-18
MX4808E (es) 1982-10-14
FI63224B (fi) 1983-01-31
SE443140B (sv) 1986-02-17
LU76957A1 (da) 1977-07-15
US4302588A (en) 1981-11-24

Similar Documents

Publication Publication Date Title
FI66371B (fi) Foerfarande foer framstaellning av heterocykliska oxipropanolaminderivater
FI72714C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla 4-acylamino-fenyl-etanolaminer.
FI63224C (fi) Foerfarande foer framstaellning av medicinskt anvaendbara 5-(3-amino-2-hydroxipropoxi)-karbostyrilderivat
BG60412B2 (bg) Нови бензазепинпроизводни,тяхното получаване и приложение като лекарствени средства
US4210753A (en) Carbostyril compounds
EP0187524B1 (en) A diaryl butyric acid derivative and the production process thereof
FI76322C (fi) Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara karbostyrilderivat.
US4363808A (en) N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines
US4147869A (en) 3,4-Dihydrocarbostyril derivatives and process for preparing the same
EP0230020B1 (en) 1,2,3,4,4a,9b-hexahydro-4a-aminoalkyldibenzofurans, a process for their preparation and their use as medicaments
US4001271A (en) 3-(isopropyl amino alkoxy)-2-phenyl-isoindolin-1-ones
US3972994A (en) Disubstituted azabicycloalkanes
US4950677A (en) Benzimidazole derivative compounds and method of making
CA1192198A (en) Quinolylacetic acid compounds, process for producing thereof and pharmaceutical compositions containing them
US4250310A (en) 3-[4-(3-Methoxy-phenyl)-piperazin-1-yl]-1-(furan-2-carbonyloxy)-propane
COSGROVE et al. Tetrazole derivatives I. Tetrazole alkamine ethers
CA2050492C (en) Piperazine compounds, processes for preparation thereof and medical uses thereof
JPS6412247B2 (da)
US3987174A (en) Isoindolin-1-one derivatives
EP0283147B1 (en) Labile ketone derivatives of 3-substituted-1-alkylamino-2-propanols and their use as beta-adrenergic blockers
JPH059181A (ja) 新規なテトラヒドロベンズアゼピン誘導体
EP0133259A2 (en) Aminoalkyl-substituted benzene derivatives, process for production thereof, and pharmaceutical composition thereof
JPS5919541B2 (ja) 新規３，４−ジヒドロカルボスチリル誘導体
US4042598A (en) Disubstituted azabicycloalkanes
JPS63225357A (ja) カルボスチリル誘導体

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: OTSUKA PHARMACEUTICAL CO. LTD.