NL7702896A - Werkwijze ter bereiding van nieuwe carbostyril- derivaten. - Google Patents

Werkwijze ter bereiding van nieuwe carbostyril- derivaten.

Info

Publication number
NL7702896A
NL7702896A NL7702896A NL7702896A NL7702896A NL 7702896 A NL7702896 A NL 7702896A NL 7702896 A NL7702896 A NL 7702896A NL 7702896 A NL7702896 A NL 7702896A NL 7702896 A NL7702896 A NL 7702896A
Authority
NL
Netherlands
Prior art keywords
preparation
carbostyril derivatives
new carbostyril
new
derivatives
Prior art date
Application number
NL7702896A
Other languages
English (en)
Other versions
NL179816B (nl
NL179816C (nl
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP51028957A external-priority patent/JPS5919541B2/ja
Priority claimed from JP51052498A external-priority patent/JPS609501B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NL7702896A publication Critical patent/NL7702896A/nl
Publication of NL179816B publication Critical patent/NL179816B/nl
Application granted granted Critical
Publication of NL179816C publication Critical patent/NL179816C/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof
    • C07D215/32Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
NLAANVRAGE7702896,A 1976-03-17 1977-03-17 Werkwijze ter bereiding van een farmaceutisch preparaat met een beta-blokkeringsactiviteit, alsmede de aldus vervaardigde farmaceutische voorwerpen, en werkwijze ter bereiding van nieuwe 5-(2-hydroxy-3-gesubstitueerd amino)propoxy-carbostyril- of 3.4-dihydrocarbostyril-verbindingen of de zouten daarvan. NL179816C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP51028957A JPS5919541B2 (ja) 1976-03-17 1976-03-17 新規3,4−ジヒドロカルボスチリル誘導体
JP51052498A JPS609501B2 (ja) 1976-05-07 1976-05-07 新規3,4−ジヒドロカルボスチリル誘導体

Publications (3)

Publication Number Publication Date
NL7702896A true NL7702896A (nl) 1977-09-20
NL179816B NL179816B (nl) 1986-06-16
NL179816C NL179816C (nl) 1986-11-17

Family

ID=26367107

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7702896,A NL179816C (nl) 1976-03-17 1977-03-17 Werkwijze ter bereiding van een farmaceutisch preparaat met een beta-blokkeringsactiviteit, alsmede de aldus vervaardigde farmaceutische voorwerpen, en werkwijze ter bereiding van nieuwe 5-(2-hydroxy-3-gesubstitueerd amino)propoxy-carbostyril- of 3.4-dihydrocarbostyril-verbindingen of de zouten daarvan.

Country Status (20)

Country Link
US (2) US4289883A (nl)
AR (1) AR211570A1 (nl)
AT (1) AT363474B (nl)
AU (1) AU513950B2 (nl)
CA (1) CA1081232A (nl)
CH (1) CH619453A5 (nl)
DE (1) DE2711719C2 (nl)
DK (1) DK154970C (nl)
ES (1) ES456963A1 (nl)
FI (1) FI63224C (nl)
FR (1) FR2344538A1 (nl)
GB (2) GB1578972A (nl)
IE (1) IE45269B1 (nl)
LU (1) LU76957A1 (nl)
MX (1) MX4808E (nl)
NL (1) NL179816C (nl)
NO (1) NO149388C (nl)
PH (1) PH15115A (nl)
PT (1) PT66312B (nl)
SE (1) SE443140B (nl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
AU518814B2 (en) * 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
FR2539413A1 (fr) * 1983-01-17 1984-07-20 Pos Lab Carbostyriloximinopropanolamines utiles comme medicaments et procede pour leur preparation
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
WO1997037967A1 (en) 1996-04-09 1997-10-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
TW483881B (en) 1996-12-03 2002-04-21 Nps Pharma Inc Calcilytic compounds
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910924A (en) * 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
JPS48103590A (nl) * 1972-04-13 1973-12-25
JPS5239035B2 (nl) * 1972-12-14 1977-10-03
US3975391A (en) * 1973-12-26 1976-08-17 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
JPS5082218A (nl) * 1973-11-10 1975-07-03
DK138890C (da) * 1973-12-26 1979-04-30 Otsuka Pharma Co Ltd Analogifremgangsmaade til fremstilling af et carbostyril- eller 3,4-dihydrocarbostyrilderivat eller syreadditionssalte deraf
US4026897A (en) * 1974-01-31 1977-05-31 Otsuka Pharmaceutical Company 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxycarbostyril derivatives
US3994901A (en) * 1974-06-13 1976-11-30 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
FI58329C (fi) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds

Also Published As

Publication number Publication date
AU513950B2 (en) 1981-01-15
NL179816B (nl) 1986-06-16
FI770827A (nl) 1977-09-18
FI63224B (fi) 1983-01-31
PH15115A (en) 1982-08-10
US4302588A (en) 1981-11-24
DK154970B (da) 1989-01-16
DK115677A (da) 1977-09-18
MX4808E (es) 1982-10-14
ATA181577A (de) 1981-01-15
FR2344538A1 (fr) 1977-10-14
AU2329977A (en) 1978-09-28
PT66312A (en) 1977-04-01
IE45269L (en) 1977-09-17
GB1578971A (en) 1980-11-12
CA1081232A (en) 1980-07-08
DE2711719A1 (de) 1977-09-22
ES456963A1 (es) 1978-07-16
DE2711719C2 (de) 1985-02-14
FI63224C (fi) 1983-05-10
SE7703000L (sv) 1977-09-18
LU76957A1 (nl) 1977-07-15
NL179816C (nl) 1986-11-17
IE45269B1 (en) 1982-07-28
AT363474B (de) 1981-08-10
AR211570A1 (es) 1978-01-30
NO149388C (no) 1984-04-11
CH619453A5 (nl) 1980-09-30
US4289883A (en) 1981-09-15
PT66312B (en) 1978-08-11
NO149388B (no) 1984-01-02
SE443140B (sv) 1986-02-17
DK154970C (da) 1989-06-12
NO770940L (no) 1977-09-20
GB1578972A (en) 1980-11-12
FR2344538B1 (nl) 1980-07-18

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Legal Events

Date Code Title Description
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee