JPS48103590A - - Google Patents
Info
- Publication number
- JPS48103590A JPS48103590A JP47037182A JP3718272A JPS48103590A JP S48103590 A JPS48103590 A JP S48103590A JP 47037182 A JP47037182 A JP 47037182A JP 3718272 A JP3718272 A JP 3718272A JP S48103590 A JPS48103590 A JP S48103590A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (32)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47037182A JPS48103590A (nl) | 1972-04-13 | 1972-04-13 | |
| JP47037181A JPS517672B2 (nl) | 1972-04-13 | 1972-04-13 | |
| JP47120953A JPS5229745B2 (nl) | 1972-04-13 | 1972-12-02 | |
| JP47125858A JPS5239036B2 (nl) | 1972-04-13 | 1972-12-14 | |
| JP47128972A JPS5241269B2 (nl) | 1972-04-13 | 1972-12-21 | |
| DK2773AA DK141603B (da) | 1972-04-13 | 1973-01-03 | Analogifremgangsmåde til fremstilling af 3,4-dihydrocarbostyril-derivater. |
| NO73105A NO140589C (no) | 1972-04-13 | 1973-01-10 | Analogifremgangsmaate for fremstilling av nye, terapeutisk aktive 3,4-dihydrokarbostyrilderivater |
| FR7300739A FR2179715B1 (nl) | 1972-04-13 | 1973-01-10 | |
| CA161,000A CA1025447A (en) | 1972-04-13 | 1973-01-11 | Process for preparing 3,4-dihydrocarbostyril derivatives |
| DE2302027A DE2302027C2 (de) | 1972-04-13 | 1973-01-16 | In 5- oder 8-Stellung substituierte 3,4-Dihydrocarbostyril-Derivate und ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel |
| YU15073A YU39001B (en) | 1972-04-13 | 1973-01-18 | Process for preparing new 3,4-dihydrocarbostyryl derivatives |
| US324905A US3910924A (en) | 1972-04-13 | 1973-01-19 | 3,4-Dihydrocarbostyril derivatives and a process for preparing the same |
| SU731873456A SU580835A3 (ru) | 1972-04-13 | 1973-01-20 | Способ получени 3,4-дигидрокарбостирильных производных или их солей |
| GB325173A GB1424571A (en) | 1972-04-13 | 1973-01-22 | 3,4-dihydrocarbostyril derivatives their preparation and pharmaceutical compositions thereof |
| GB3417075A GB1424572A (en) | 1972-04-13 | 1973-01-22 | 3,4-dihydrocarbostyril derivatives and their preparation |
| BE794669D BE794669A (fr) | 1972-04-13 | 1973-01-29 | Derives de 3,4-dihydrocarbostyryle et leur procede de preparation |
| FI279/73A FI53703C (fi) | 1972-04-13 | 1973-01-31 | Foerfarande foer framstaellning av beta-adrenergiskt blockerande 3,4-dihydrokarbostyrilderivat |
| DD168643A DD108293A5 (nl) | 1972-04-13 | 1973-02-02 | |
| DD178082*A DD112446A5 (nl) | 1972-04-13 | 1973-02-02 | |
| SE7301863A SE380018B (nl) | 1972-04-13 | 1973-02-09 | |
| AR246548A AR209575A1 (es) | 1972-04-13 | 1973-02-12 | Un procedimiento para preparar nuevos derivados sustituidos de 5-,6-,7-u8-(3-amino-2-oxisustituido)-propoxi-3,4-dihidrocarbostirilo y de 5-,6-,7-u8-(3-amino-2-hidroxi)propoxi -3,4-dihidrocarbostirilo |
| NL7302353.A NL158176B (nl) | 1972-04-13 | 1973-02-20 | Werkwijze voor het bereiden van een geneesmiddel met (beta)-adrenenergisch blokkerende werking, gevormd geneesmiddel verkregen onder toepassing daarvan, alsmede werkwijze voor het bereiden van een verbinding geschikt voor toepassing bij voornoemde werkwijze. |
| CH1554675A CH574930A5 (en) | 1972-04-13 | 1973-03-19 | (2-hydroxy-3-amino)-propoxy-(3,4-dihydro)-carbostyril - derivs - beta-adrenergic blocking agents |
| CH393973A CH575929A5 (nl) | 1972-04-13 | 1973-03-19 | |
| AU54386/73A AU475964B2 (en) | 1972-04-13 | 1973-04-11 | Process for preparing 3,4-dihydrocarbostyril derivatives |
| DK138076A DK152492C (da) | 1972-04-13 | 1976-03-29 | 3,4-dihydrocarbostyril-derivater til anvendelse som mellemprodukter til fremstilling af biologisk aktive 3,4-dihydrocarbostyril-derivater |
| DK137976A DK137976A (da) | 1972-04-13 | 1976-03-29 | Fremgangsmade til fremstilling af 2,4-dihydrocarbostyril-derivater |
| CA257,001A CA1025453A (en) | 1972-04-13 | 1976-07-15 | Process for preparing 3,4-dihydrocarbostyril derivatives |
| FI770713A FI61894C (fi) | 1972-04-13 | 1977-03-07 | Som mellanprodukter anvaendbara 1-substituerade eller 1-osubstituerade 5- 6- 7- eller 8-(2,3-substituerade)-propoxi-3,4-dihydroxikarbostyrilderivat |
| YU2549/79A YU41187B (en) | 1972-04-13 | 1979-10-19 | Process for preparing new 3,4-dihydrocarbostyrye derivatives |
| US06/162,353 US4329468A (en) | 1972-04-13 | 1980-06-24 | 3,4-Dihydrocarbostyril derivatives |
| HK194/81A HK19481A (en) | 1972-04-13 | 1981-05-14 | 3,4-dihydrocarbostyril derivatives,their preparation,and pharmaceutical compositions thereof |
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47037181A JPS517672B2 (nl) | 1972-04-13 | 1972-04-13 | |
| JP47037182A JPS48103590A (nl) | 1972-04-13 | 1972-04-13 | |
| JP47092558A JPS5241268B2 (nl) | 1972-09-14 | 1972-09-14 | |
| JP47092560A JPS5246231B2 (nl) | 1972-09-14 | 1972-09-14 | |
| JP9255772A JPS5324431B2 (nl) | 1972-09-14 | 1972-09-14 | |
| JP47120953A JPS5229745B2 (nl) | 1972-04-13 | 1972-12-02 | |
| JP47125858A JPS5239036B2 (nl) | 1972-04-13 | 1972-12-14 | |
| JP47128972A JPS5241269B2 (nl) | 1972-04-13 | 1972-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS48103590A true JPS48103590A (nl) | 1973-12-25 |
Family
ID=27572212
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP47037181A Expired JPS517672B2 (nl) | 1972-04-13 | 1972-04-13 | |
| JP47037182A Pending JPS48103590A (nl) | 1972-04-13 | 1972-04-13 | |
| JP47120953A Expired JPS5229745B2 (nl) | 1972-04-13 | 1972-12-02 | |
| JP47125858A Expired JPS5239036B2 (nl) | 1972-04-13 | 1972-12-14 | |
| JP47128972A Expired JPS5241269B2 (nl) | 1972-04-13 | 1972-12-21 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP47037181A Expired JPS517672B2 (nl) | 1972-04-13 | 1972-04-13 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP47120953A Expired JPS5229745B2 (nl) | 1972-04-13 | 1972-12-02 | |
| JP47125858A Expired JPS5239036B2 (nl) | 1972-04-13 | 1972-12-14 | |
| JP47128972A Expired JPS5241269B2 (nl) | 1972-04-13 | 1972-12-21 |
Country Status (17)
| Country | Link |
|---|---|
| JP (5) | JPS517672B2 (nl) |
| AR (1) | AR209575A1 (nl) |
| AU (1) | AU475964B2 (nl) |
| BE (1) | BE794669A (nl) |
| CA (1) | CA1025447A (nl) |
| CH (1) | CH575929A5 (nl) |
| DD (2) | DD108293A5 (nl) |
| DE (1) | DE2302027C2 (nl) |
| DK (1) | DK141603B (nl) |
| FI (1) | FI53703C (nl) |
| FR (1) | FR2179715B1 (nl) |
| GB (2) | GB1424572A (nl) |
| HK (1) | HK19481A (nl) |
| NL (1) | NL158176B (nl) |
| NO (1) | NO140589C (nl) |
| SE (1) | SE380018B (nl) |
| YU (1) | YU41187B (nl) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5082218A (nl) * | 1973-11-10 | 1975-07-03 | ||
| US4022784A (en) * | 1974-01-31 | 1977-05-10 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives |
| US4137331A (en) | 1974-06-19 | 1979-01-30 | Sandoz Ltd. | 3-Piperidino-2-hydroxypropoxy substituted-2-indolinones |
| JPS516971A (en) * | 1974-07-08 | 1976-01-20 | Otsuka Pharma Co Ltd | Nitoro 3*44 jihidorokarubosuchirirujudotaino seizoho |
| JPS5129486A (en) * | 1974-09-02 | 1976-03-12 | Otsuka Pharma Co Ltd | * 33 arukiruamino 22 hidorokishi * purohokishi 3 44 jihidorokarubosuchirirujudotai no seizoho |
| JPS5148674A (en) * | 1974-10-17 | 1976-04-26 | Otsuka Pharma Co Ltd | 3 44 jihidorokarubosuchirirujudotaino seizoho |
| JPS5152179A (ja) * | 1974-10-31 | 1976-05-08 | Otsuka Pharma Co Ltd | Karubosuchirirujudotaino seizoho |
| JPS5152180A (ja) * | 1974-10-31 | 1976-05-08 | Otsuka Pharma Co Ltd | Karubosuchirirujudotaino seizoho |
| JPS5152178A (ja) * | 1974-10-31 | 1976-05-08 | Otsuka Pharma Co Ltd | Karubosuchirirujudotaino seizoho |
| FI58329C (fi) * | 1974-11-08 | 1981-01-12 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat |
| US4081447A (en) * | 1975-04-09 | 1978-03-28 | Abbott Laboratories | 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof |
| CH619453A5 (nl) * | 1976-03-17 | 1980-09-30 | Otsuka Pharma Co Ltd | |
| GB1574665A (en) * | 1976-05-08 | 1980-09-10 | Otsuka Pharma Co Ltd | 3,4-dihydrocarbostyril derivatives and process for preparing the same |
| US4146630A (en) * | 1976-11-12 | 1979-03-27 | Boehringer Mannheim Gmbh | Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers |
| JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| DE2960178D1 (en) * | 1978-06-06 | 1981-04-09 | Hoechst Ag | New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation |
| DE2827566A1 (de) * | 1978-06-23 | 1980-01-10 | Boehringer Mannheim Gmbh | 1,2-dihydro-chinolin-2-on-derivate und verfahren zu ihrer herstellung |
| AU518814B2 (en) * | 1979-01-30 | 1981-10-22 | Otsuka Pharamaceutical Co. | Glaucoma treatment |
| DE3034237A1 (de) * | 1979-09-18 | 1981-04-16 | Otsuka Pharmaceutical Co. Ltd., Tokyo | Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel |
| JPS56122356A (en) * | 1980-02-29 | 1981-09-25 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| JPS58103343A (ja) * | 1981-12-15 | 1983-06-20 | Ota Seiyaku Kk | プロパノ−ルアミン化合物の製造法 |
| JPS597186A (ja) * | 1982-07-02 | 1984-01-14 | Ota Seiyaku Kk | １，３，２−ジオキサチオラン２−オキシド誘導体 |
| JPS63193086U (nl) * | 1987-05-30 | 1988-12-13 | ||
| DE3808136A1 (de) * | 1988-03-11 | 1989-09-21 | Thomae Gmbh Dr K | Arzneimittel, enthaltend chinolin-2,5-dione, neue chinolin-2,5-dione und verfahren zu ihrer herstellung |
| US5266577A (en) * | 1988-08-10 | 1993-11-30 | Otsuka Pharmaceutical Company Ltd. | Method of treating congestive heart failure using carbostyril derivatives |
| EP0355583B1 (en) * | 1988-08-10 | 1995-01-25 | Otsuka Pharmaceutical Co., Ltd. | Cardiotonics |
| AU653060B2 (en) * | 1991-08-23 | 1994-09-15 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative and platelet agglutination inhibitor |
| ES2048108B1 (es) * | 1992-07-17 | 1994-10-01 | Lusochimica Spa | Procedimiento para la preparacion de 5-(3-terc-butilamino-2-hidroxipropoxi)-3,4-dihidrocarboestirilo. |
| IT1264816B1 (it) * | 1993-07-28 | 1996-10-10 | Pergam Srl | Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile |
| CZ300351B6 (cs) * | 2005-05-26 | 2009-04-29 | Zentiva, A. S. | Zpusob prípravy 7-hydroxy-3,4-dihydrokarbostyrilu |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1058822A (en) * | 1963-07-30 | 1967-02-15 | Ici Ltd | 3-amino-2-hydroxypropoxy heterocyclic derivatives |
| CH514611A (de) * | 1968-07-05 | 1971-10-31 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von Derivaten des 2-Oxo-1,2-dihydro-chinolins |
-
1972
- 1972-04-13 JP JP47037181A patent/JPS517672B2/ja not_active Expired
- 1972-04-13 JP JP47037182A patent/JPS48103590A/ja active Pending
- 1972-12-02 JP JP47120953A patent/JPS5229745B2/ja not_active Expired
- 1972-12-14 JP JP47125858A patent/JPS5239036B2/ja not_active Expired
- 1972-12-21 JP JP47128972A patent/JPS5241269B2/ja not_active Expired
-
1973
- 1973-01-03 DK DK2773AA patent/DK141603B/da active Protection Beyond IP Right Term
- 1973-01-10 NO NO73105A patent/NO140589C/no unknown
- 1973-01-10 FR FR7300739A patent/FR2179715B1/fr not_active Expired
- 1973-01-11 CA CA161,000A patent/CA1025447A/en not_active Expired
- 1973-01-16 DE DE2302027A patent/DE2302027C2/de not_active Expired
- 1973-01-22 GB GB3417075A patent/GB1424572A/en not_active Expired
- 1973-01-22 GB GB325173A patent/GB1424571A/en not_active Expired
- 1973-01-29 BE BE794669D patent/BE794669A/xx active Protection Beyond IP Right Term
- 1973-01-31 FI FI279/73A patent/FI53703C/fi active
- 1973-02-02 DD DD168643A patent/DD108293A5/xx unknown
- 1973-02-02 DD DD178082*A patent/DD112446A5/xx unknown
- 1973-02-09 SE SE7301863A patent/SE380018B/xx unknown
- 1973-02-12 AR AR246548A patent/AR209575A1/es active
- 1973-02-20 NL NL7302353.A patent/NL158176B/nl not_active IP Right Cessation
- 1973-03-19 CH CH393973A patent/CH575929A5/xx active Protection Beyond IP Right Term
- 1973-04-11 AU AU54386/73A patent/AU475964B2/en not_active Expired
-
1979
- 1979-10-19 YU YU2549/79A patent/YU41187B/xx unknown
-
1981
- 1981-05-14 HK HK194/81A patent/HK19481A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS517672B2 (nl) | 1976-03-10 |
| NO140589B (no) | 1979-06-25 |
| AU5438673A (en) | 1974-10-17 |
| DD108293A5 (nl) | 1974-09-12 |
| GB1424571A (en) | 1976-02-11 |
| NL158176B (nl) | 1978-10-16 |
| JPS48103589A (nl) | 1973-12-25 |
| DE2302027A1 (de) | 1973-12-06 |
| FI53703B (nl) | 1978-03-31 |
| NL7302353A (nl) | 1973-10-16 |
| YU254979A (en) | 1982-10-31 |
| JPS5241269B2 (nl) | 1977-10-17 |
| CH575929A5 (nl) | 1976-05-31 |
| AR209575A1 (es) | 1977-05-13 |
| AU475964B2 (en) | 1976-09-09 |
| BE794669A (fr) | 1973-05-16 |
| CA1025447A (en) | 1978-01-31 |
| DD112446A5 (nl) | 1975-04-12 |
| JPS4982673A (nl) | 1974-08-08 |
| DK141603C (nl) | 1980-10-06 |
| HK19481A (en) | 1981-05-22 |
| JPS4976878A (nl) | 1974-07-24 |
| DE2302027C2 (de) | 1983-03-17 |
| YU41187B (en) | 1986-12-31 |
| JPS5239036B2 (nl) | 1977-10-03 |
| SE380018B (nl) | 1975-10-27 |
| FR2179715B1 (nl) | 1976-12-03 |
| NO140589C (no) | 1979-10-03 |
| DK141603B (da) | 1980-05-05 |
| JPS4981373A (nl) | 1974-08-06 |
| FI53703C (fi) | 1978-07-10 |
| FR2179715A1 (nl) | 1973-11-23 |
| GB1424572A (en) | 1976-02-11 |
| JPS5229745B2 (nl) | 1977-08-03 |