NO140589C - Analogifremgangsmaate for fremstilling av nye, terapeutisk aktive 3,4-dihydrokarbostyrilderivater - Google Patents

Analogifremgangsmaate for fremstilling av nye, terapeutisk aktive 3,4-dihydrokarbostyrilderivater

Info

Publication number
NO140589C
NO140589C NO73105A NO10573A NO140589C NO 140589 C NO140589 C NO 140589C NO 73105 A NO73105 A NO 73105A NO 10573 A NO10573 A NO 10573A NO 140589 C NO140589 C NO 140589C
Authority
NO
Norway
Prior art keywords
therapeutically active
preparing new
new therapeutically
dihydrocarbostyril derivatives
analogical procedure
Prior art date
Application number
NO73105A
Other languages
English (en)
Other versions
NO140589B (no
Inventor
Kazuyuki Nakagawa
Nanami Murakami
Shiro Yoshizaki
Hideo Mori
Michiaki Tominaga
Yasumitsu Tamura
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP47092558A external-priority patent/JPS5241268B2/ja
Priority claimed from JP47092560A external-priority patent/JPS5246231B2/ja
Priority claimed from JP9255772A external-priority patent/JPS5324431B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO140589B publication Critical patent/NO140589B/no
Publication of NO140589C publication Critical patent/NO140589C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO73105A 1972-04-13 1973-01-10 Analogifremgangsmaate for fremstilling av nye, terapeutisk aktive 3,4-dihydrokarbostyrilderivater NO140589C (no)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP47037182A JPS48103590A (no) 1972-04-13 1972-04-13
JP47037181A JPS517672B2 (no) 1972-04-13 1972-04-13
JP47092558A JPS5241268B2 (no) 1972-09-14 1972-09-14
JP47092560A JPS5246231B2 (no) 1972-09-14 1972-09-14
JP9255772A JPS5324431B2 (no) 1972-09-14 1972-09-14
JP47120953A JPS5229745B2 (no) 1972-04-13 1972-12-02
JP47125858A JPS5239036B2 (no) 1972-04-13 1972-12-14
JP47128972A JPS5241269B2 (no) 1972-04-13 1972-12-21

Publications (2)

Publication Number Publication Date
NO140589B NO140589B (no) 1979-06-25
NO140589C true NO140589C (no) 1979-10-03

Family

ID=27572212

Family Applications (1)

Application Number Title Priority Date Filing Date
NO73105A NO140589C (no) 1972-04-13 1973-01-10 Analogifremgangsmaate for fremstilling av nye, terapeutisk aktive 3,4-dihydrokarbostyrilderivater

Country Status (17)

Country Link
JP (5) JPS517672B2 (no)
AR (1) AR209575A1 (no)
AU (1) AU475964B2 (no)
BE (1) BE794669A (no)
CA (1) CA1025447A (no)
CH (1) CH575929A5 (no)
DD (2) DD112446A5 (no)
DE (1) DE2302027C2 (no)
DK (1) DK141603B (no)
FI (1) FI53703C (no)
FR (1) FR2179715B1 (no)
GB (2) GB1424572A (no)
HK (1) HK19481A (no)
NL (1) NL158176B (no)
NO (1) NO140589C (no)
SE (1) SE380018B (no)
YU (1) YU41187B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5082218A (no) * 1973-11-10 1975-07-03
US4022784A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives
US4137331A (en) 1974-06-19 1979-01-30 Sandoz Ltd. 3-Piperidino-2-hydroxypropoxy substituted-2-indolinones
JPS516971A (en) * 1974-07-08 1976-01-20 Otsuka Pharma Co Ltd Nitoro 3*44 jihidorokarubosuchirirujudotaino seizoho
JPS5129486A (en) * 1974-09-02 1976-03-12 Otsuka Pharma Co Ltd * 33 arukiruamino 22 hidorokishi * purohokishi 3 44 jihidorokarubosuchirirujudotai no seizoho
JPS5148674A (en) * 1974-10-17 1976-04-26 Otsuka Pharma Co Ltd 3 44 jihidorokarubosuchirirujudotaino seizoho
JPS5152180A (ja) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd Karubosuchirirujudotaino seizoho
JPS5152179A (ja) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd Karubosuchirirujudotaino seizoho
JPS5152178A (ja) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd Karubosuchirirujudotaino seizoho
FI58329C (fi) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH619453A5 (no) * 1976-03-17 1980-09-30 Otsuka Pharma Co Ltd
DE2719562C2 (de) * 1976-05-08 1986-05-07 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo 3, 4-Dihydrocarbostyrilderivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
DE2960178D1 (en) * 1978-06-06 1981-04-09 Hoechst Ag New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation
DE2827566A1 (de) * 1978-06-23 1980-01-10 Boehringer Mannheim Gmbh 1,2-dihydro-chinolin-2-on-derivate und verfahren zu ihrer herstellung
AU518814B2 (en) * 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
JPS56122356A (en) * 1980-02-29 1981-09-25 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS58103343A (ja) * 1981-12-15 1983-06-20 Ota Seiyaku Kk プロパノ−ルアミン化合物の製造法
JPS597186A (ja) * 1982-07-02 1984-01-14 Ota Seiyaku Kk １，３，２−ジオキサチオラン２−オキシド誘導体
JPS63193086U (no) * 1987-05-30 1988-12-13
DE3808136A1 (de) * 1988-03-11 1989-09-21 Thomae Gmbh Dr K Arzneimittel, enthaltend chinolin-2,5-dione, neue chinolin-2,5-dione und verfahren zu ihrer herstellung
DK391189A (da) * 1988-08-10 1990-02-11 Otsuka Pharma Co Ltd Carbostyrilderivater
US5266577A (en) * 1988-08-10 1993-11-30 Otsuka Pharmaceutical Company Ltd. Method of treating congestive heart failure using carbostyril derivatives
WO1993004042A1 (fr) * 1991-08-23 1993-03-04 Otsuka Pharmaceutical Co., Ltd. Derive de carbostyrile et antiagregant plaquettaire
ES2048108B1 (es) * 1992-07-17 1994-10-01 Lusochimica Spa Procedimiento para la preparacion de 5-(3-terc-butilamino-2-hidroxipropoxi)-3,4-dihidrocarboestirilo.
IT1264816B1 (it) * 1993-07-28 1996-10-10 Pergam Srl Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile
CZ300351B6 (cs) * 2005-05-26 2009-04-29 Zentiva, A. S. Zpusob prípravy 7-hydroxy-3,4-dihydrokarbostyrilu

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
CH523899A (de) * 1968-07-05 1972-06-15 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Derivaten des 2-Oxo-1,2-dihydro-chinolins

Also Published As

Publication number Publication date
FR2179715B1 (no) 1976-12-03
AU475964B2 (en) 1976-09-09
BE794669A (fr) 1973-05-16
GB1424571A (en) 1976-02-11
JPS4976878A (no) 1974-07-24
JPS48103589A (no) 1973-12-25
SE380018B (no) 1975-10-27
GB1424572A (en) 1976-02-11
DE2302027A1 (de) 1973-12-06
JPS48103590A (no) 1973-12-25
JPS5241269B2 (no) 1977-10-17
JPS517672B2 (no) 1976-03-10
CA1025447A (en) 1978-01-31
FR2179715A1 (no) 1973-11-23
NL7302353A (no) 1973-10-16
YU41187B (en) 1986-12-31
DD108293A5 (no) 1974-09-12
JPS5229745B2 (no) 1977-08-03
JPS4982673A (no) 1974-08-08
NO140589B (no) 1979-06-25
HK19481A (en) 1981-05-22
AU5438673A (en) 1974-10-17
NL158176B (nl) 1978-10-16
DK141603C (no) 1980-10-06
JPS4981373A (no) 1974-08-06
DE2302027C2 (de) 1983-03-17
YU254979A (en) 1982-10-31
FI53703B (no) 1978-03-31
JPS5239036B2 (no) 1977-10-03
AR209575A1 (es) 1977-05-13
DD112446A5 (no) 1975-04-12
DK141603B (da) 1980-05-05
FI53703C (fi) 1978-07-10
CH575929A5 (no) 1976-05-31

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