YU254979A - Process for preparing new 3,4-dihydrocarbostyryl-derivatives - Google Patents

Process for preparing new 3,4-dihydrocarbostyryl-derivatives

Info

Publication number
YU254979A
YU254979A YU02549/79A YU254979A YU254979A YU 254979 A YU254979 A YU 254979A YU 02549/79 A YU02549/79 A YU 02549/79A YU 254979 A YU254979 A YU 254979A YU 254979 A YU254979 A YU 254979A
Authority
YU
Yugoslavia
Prior art keywords
dihydrocarbostyryl
derivatives
preparing new
preparing
new
Prior art date
Application number
YU02549/79A
Other versions
YU41187B (en
Inventor
K Nakawa
N Murakami
S Yoshizaki
H Mori
M Tominaga
Y Tamura
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP47092560A external-priority patent/JPS5246231B2/ja
Priority claimed from JP9255772A external-priority patent/JPS5324431B2/ja
Priority claimed from JP47092558A external-priority patent/JPS5241268B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of YU254979A publication Critical patent/YU254979A/en
Publication of YU41187B publication Critical patent/YU41187B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof
YU2549/79A 1972-04-13 1979-10-19 Process for preparing new 3,4-dihydrocarbostyrye derivatives YU41187B (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP47037181A JPS517672B2 (en) 1972-04-13 1972-04-13
JP47037182A JPS48103590A (en) 1972-04-13 1972-04-13
JP47092560A JPS5246231B2 (en) 1972-09-14 1972-09-14
JP9255772A JPS5324431B2 (en) 1972-09-14 1972-09-14
JP47092558A JPS5241268B2 (en) 1972-09-14 1972-09-14
JP47120953A JPS5229745B2 (en) 1972-04-13 1972-12-02
JP47125858A JPS5239036B2 (en) 1972-04-13 1972-12-14
JP47128972A JPS5241269B2 (en) 1972-04-13 1972-12-21

Publications (2)

Publication Number Publication Date
YU254979A true YU254979A (en) 1982-10-31
YU41187B YU41187B (en) 1986-12-31

Family

ID=27572212

Family Applications (1)

Application Number Title Priority Date Filing Date
YU2549/79A YU41187B (en) 1972-04-13 1979-10-19 Process for preparing new 3,4-dihydrocarbostyrye derivatives

Country Status (17)

Country Link
JP (5) JPS517672B2 (en)
AR (1) AR209575A1 (en)
AU (1) AU475964B2 (en)
BE (1) BE794669A (en)
CA (1) CA1025447A (en)
CH (1) CH575929A5 (en)
DD (2) DD108293A5 (en)
DE (1) DE2302027C2 (en)
DK (1) DK141603B (en)
FI (1) FI53703C (en)
FR (1) FR2179715B1 (en)
GB (2) GB1424572A (en)
HK (1) HK19481A (en)
NL (1) NL158176B (en)
NO (1) NO140589C (en)
SE (1) SE380018B (en)
YU (1) YU41187B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5082218A (en) * 1973-11-10 1975-07-03
US4022784A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives
US4137331A (en) 1974-06-19 1979-01-30 Sandoz Ltd. 3-Piperidino-2-hydroxypropoxy substituted-2-indolinones
JPS516971A (en) * 1974-07-08 1976-01-20 Otsuka Pharma Co Ltd Nitoro 3*44 jihidorokarubosuchirirujudotaino seizoho
JPS5129486A (en) * 1974-09-02 1976-03-12 Otsuka Pharma Co Ltd * 33 arukiruamino 22 hidorokishi * purohokishi 3 44 jihidorokarubosuchirirujudotai no seizoho
JPS5148674A (en) * 1974-10-17 1976-04-26 Otsuka Pharma Co Ltd 3 44 jihidorokarubosuchirirujudotaino seizoho
JPS5152180A (en) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd KARUBOSUCHIRIRU JUDOTAINO SEIZOHO
JPS5152178A (en) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd KARUBOSUCHIRIRU JUDOTAINO SEIZOHO
JPS5152179A (en) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd KARUBOSUCHIRIRU JUDOTAINO SEIZOHO
FI58329C (en) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd PROCEDURE FOR FRAMSTATION OF I 8-STATIONARY SUBSTITUTES 5- (3'-ALKYLAMINO-2'-HYDROXY) PROPOXI-3,4-DIHYDROCARBOSTYRILDER
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH619453A5 (en) * 1976-03-17 1980-09-30 Otsuka Pharma Co Ltd
GB1574665A (en) * 1976-05-08 1980-09-10 Otsuka Pharma Co Ltd 3,4-dihydrocarbostyril derivatives and process for preparing the same
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
DE2960178D1 (en) * 1978-06-06 1981-04-09 Hoechst Ag New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation
DE2827566A1 (en) * 1978-06-23 1980-01-10 Boehringer Mannheim Gmbh 1,2-DIHYDRO-CHINOLIN-2-ON DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
AU518814B2 (en) * 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
DE3034237A1 (en) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo CARBOSTYRIL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND ANTIHISTAMINICALLY ACTIVE AGENTS CONTAINING THESE COMPOUNDS
JPS56122356A (en) * 1980-02-29 1981-09-25 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS58103343A (en) * 1981-12-15 1983-06-20 Ota Seiyaku Kk Preparation of propanolamine compound
JPS597186A (en) * 1982-07-02 1984-01-14 Ota Seiyaku Kk 1,3,2-dioxathiolane 2-oxide derivative
JPS63193086U (en) * 1987-05-30 1988-12-13
DE3808136A1 (en) * 1988-03-11 1989-09-21 Thomae Gmbh Dr K DRUGS CONTAINING CHINOLINE-2,5-DIONE, NEW CHINOLINE-2,5-DIONE AND METHOD OF PREPARING THEM
US5266577A (en) * 1988-08-10 1993-11-30 Otsuka Pharmaceutical Company Ltd. Method of treating congestive heart failure using carbostyril derivatives
ES2070151T3 (en) * 1988-08-10 1995-06-01 Otsuka Pharma Co Ltd CARDIOTONIC AGENTS.
US5506239A (en) * 1991-08-23 1996-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative and platelets aggregation inhibitory agent
ES2048108B1 (en) * 1992-07-17 1994-10-01 Lusochimica Spa PROCEDURE FOR THE PREPARATION OF 5- (3-TERC-BUTILAMINO-2-HIDROXIPROPOXI) -3,4-DIHIDROCARBOESTIRILO.
IT1264816B1 (en) * 1993-07-28 1996-10-10 Pergam Srl Process for the preparation of 3,4-dihydrocarbostyryl derivatives
CZ300351B6 (en) * 2005-05-26 2009-04-29 Zentiva, A. S. Process for preparing 7-hydroxy-3,4-dihydrocarbostyril

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
CH523899A (en) * 1968-07-05 1972-06-15 Cassella Farbwerke Mainkur Ag 2-oxo-1,2-dihydroquinoline derivs

Also Published As

Publication number Publication date
DE2302027A1 (en) 1973-12-06
DE2302027C2 (en) 1983-03-17
JPS4982673A (en) 1974-08-08
DD108293A5 (en) 1974-09-12
FI53703C (en) 1978-07-10
JPS4976878A (en) 1974-07-24
CH575929A5 (en) 1976-05-31
JPS5241269B2 (en) 1977-10-17
YU41187B (en) 1986-12-31
DK141603C (en) 1980-10-06
HK19481A (en) 1981-05-22
NO140589B (en) 1979-06-25
JPS5239036B2 (en) 1977-10-03
GB1424572A (en) 1976-02-11
JPS5229745B2 (en) 1977-08-03
DD112446A5 (en) 1975-04-12
JPS517672B2 (en) 1976-03-10
FR2179715A1 (en) 1973-11-23
FR2179715B1 (en) 1976-12-03
AU475964B2 (en) 1976-09-09
AR209575A1 (en) 1977-05-13
DK141603B (en) 1980-05-05
NL158176B (en) 1978-10-16
JPS48103590A (en) 1973-12-25
NO140589C (en) 1979-10-03
CA1025447A (en) 1978-01-31
BE794669A (en) 1973-05-16
FI53703B (en) 1978-03-31
NL7302353A (en) 1973-10-16
JPS4981373A (en) 1974-08-06
SE380018B (en) 1975-10-27
GB1424571A (en) 1976-02-11
AU5438673A (en) 1974-10-17
JPS48103589A (en) 1973-12-25

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