HU173507B - Process for preparing 11,15-bis-tetrahydropyranyloxy-omega-tetranor-16-phenoxy-prostaglandin derivatives - Google Patents
Process for preparing 11,15-bis-tetrahydropyranyloxy-omega-tetranor-16-phenoxy-prostaglandin derivativesInfo
- Publication number
- HU173507B HU173507B HU73PI451A HUPI000451A HU173507B HU 173507 B HU173507 B HU 173507B HU 73PI451 A HU73PI451 A HU 73PI451A HU PI000451 A HUPI000451 A HU PI000451A HU 173507 B HU173507 B HU 173507B
- Authority
- HU
- Hungary
- Prior art keywords
- tetranor
- tetrahydropyranyloxy
- omega
- phenoxy
- bis
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30481372A | 1972-11-08 | 1972-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU173507B true HU173507B (en) | 1979-05-28 |
Family
ID=23178133
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU72PI00000399A HU172703B (en) | 1972-11-08 | 1973-11-08 | Process for producing 16-phenoxy-omega-tetranor-prostaglandine derivatives |
| HU73PI451A HU173507B (en) | 1972-11-08 | 1973-11-08 | Process for preparing 11,15-bis-tetrahydropyranyloxy-omega-tetranor-16-phenoxy-prostaglandin derivatives |
| HU73PI00000452A HU171819B (en) | 1972-11-08 | 1973-11-08 | Process for producing 2-oxo-3-phenoxypropyl-phosphonic acid-dialkyl-ester derivatives |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU72PI00000399A HU172703B (en) | 1972-11-08 | 1973-11-08 | Process for producing 16-phenoxy-omega-tetranor-prostaglandine derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU73PI00000452A HU171819B (en) | 1972-11-08 | 1973-11-08 | Process for producing 2-oxo-3-phenoxypropyl-phosphonic acid-dialkyl-ester derivatives |
Country Status (29)
| Country | Link |
|---|---|
| JP (3) | JPS5416491B2 (en) |
| AR (3) | AR200585A1 (en) |
| AT (3) | AT367034B (en) |
| AU (1) | AU470375B2 (en) |
| BE (1) | BE806995A (en) |
| CA (3) | CA1085831A (en) |
| CH (1) | CH597176A5 (en) |
| CS (3) | CS182793B2 (en) |
| DD (4) | DD118856A5 (en) |
| DE (1) | DE2355540C2 (en) |
| DK (1) | DK144247C (en) |
| ES (3) | ES420325A1 (en) |
| FI (1) | FI60389C (en) |
| FR (3) | FR2205335B1 (en) |
| GB (3) | GB1456514A (en) |
| HK (3) | HK28179A (en) |
| HU (3) | HU172703B (en) |
| IE (1) | IE39537B1 (en) |
| IL (1) | IL43589A (en) |
| IN (1) | IN139384B (en) |
| KE (3) | KE2930A (en) |
| MY (3) | MY7900246A (en) |
| NL (1) | NL164273C (en) |
| NO (3) | NO147836C (en) |
| PH (3) | PH13272A (en) |
| SE (4) | SE448992B (en) |
| SU (4) | SU584766A3 (en) |
| YU (3) | YU39715B (en) |
| ZA (1) | ZA738554B (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3929862A (en) * | 1974-01-08 | 1975-12-30 | Upjohn Co | Substituted tolylesters of PGF{HD 2{B {60 |
| US3986764A (en) * | 1975-03-31 | 1976-10-19 | Gte Automatic Electric Laboratories Incorporated | Panel for supporting a pair of elongated mating connectors and selectively locking them together |
| GB1506816A (en) * | 1975-03-31 | 1978-04-12 | Upjohn Co | Prostaglandins |
| ES449162A1 (en) * | 1975-06-23 | 1977-12-16 | Syntex Inc | 16-Phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives |
| GB1516414A (en) * | 1975-08-22 | 1978-07-05 | Ici Ltd | Prostane derivatives |
| SE7809008L (en) * | 1977-12-12 | 1979-06-13 | Upjohn Co | USE OF PROSTAGLAND TYPE AMIDES TO CONTROL OR REGULATE THE REPRODUCTION CYCLE IN INDIVIDUALS OF MAMMALS |
| DK523378A (en) * | 1978-01-16 | 1979-07-17 | Pfizer | PROCEDURE FOR THE PREPARATION OF N- (TETRAZOL-5-YL) PROSTAGLANDIN CARBOXAMIDES OR SALTS THEREOF |
| US6048895A (en) * | 1997-09-09 | 2000-04-11 | The Procter & Gamble Company | Aromatic C16-C20 substituted tetrahydro prostaglandins useful as FP agonists |
| PL350917A1 (en) | 1999-03-05 | 2003-02-10 | Procter & Gamble | C16 unsaturated fp-selective prostaglandins analogs |
| US6894175B1 (en) | 1999-08-04 | 2005-05-17 | The Procter & Gamble Company | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use |
| US20020037914A1 (en) | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
| US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
| US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
| JP2002329615A (en) * | 2001-05-02 | 2002-11-15 | Ohira Denshi Kk | Toroidal coil |
| US6476064B1 (en) * | 2001-06-13 | 2002-11-05 | Allergan, Inc. | Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents |
| WO2006047466A2 (en) | 2004-10-21 | 2006-05-04 | Duke University | Ophthamological drugs |
| US8722739B2 (en) | 2008-10-29 | 2014-05-13 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
| US8623918B2 (en) | 2008-10-29 | 2014-01-07 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1324737A (en) * | 1970-11-02 | 1973-07-25 | Upjohn Co | Prostaglandins and the preparation thereof |
| IE37602B1 (en) * | 1971-05-11 | 1977-08-31 | Ici Ltd | Cyclopentane derivatives |
-
1972
- 1972-11-07 DD DD182498*A patent/DD118856A5/xx unknown
-
1973
- 1973-10-29 SE SE7314686A patent/SE448992B/en unknown
- 1973-11-07 DD DD174504A patent/DD109212A5/xx unknown
- 1973-11-07 ZA ZA738554A patent/ZA738554B/en unknown
- 1973-11-07 NL NL7315263.A patent/NL164273C/en not_active IP Right Cessation
- 1973-11-07 CA CA185,274A patent/CA1085831A/en not_active Expired
- 1973-11-07 GB GB2285876A patent/GB1456514A/en not_active Expired
- 1973-11-07 CH CH1563973A patent/CH597176A5/xx not_active IP Right Cessation
- 1973-11-07 BE BE1005485A patent/BE806995A/en not_active IP Right Cessation
- 1973-11-07 IE IE2002/73A patent/IE39537B1/en unknown
- 1973-11-07 PH PH15191A patent/PH13272A/en unknown
- 1973-11-07 AR AR250885A patent/AR200585A1/en active
- 1973-11-07 YU YU2880/73A patent/YU39715B/en unknown
- 1973-11-07 GB GB5175873A patent/GB1456512A/en not_active Expired
- 1973-11-07 DK DK601073A patent/DK144247C/en not_active IP Right Cessation
- 1973-11-07 ES ES420325A patent/ES420325A1/en not_active Expired
- 1973-11-07 IN IN2448/CAL/73A patent/IN139384B/en unknown
- 1973-11-07 DD DD182499*A patent/DD119411A5/xx unknown
- 1973-11-07 JP JP12527273A patent/JPS5416491B2/ja not_active Expired
- 1973-11-07 IL IL43589A patent/IL43589A/en unknown
- 1973-11-07 AT AT0936973A patent/AT367034B/en not_active IP Right Cessation
- 1973-11-07 AU AU62247/73A patent/AU470375B2/en not_active Expired
- 1973-11-07 FR FR7339544A patent/FR2205335B1/fr not_active Expired
- 1973-11-07 NO NO4288/73A patent/NO147836C/en unknown
- 1973-11-07 FI FI3443/73A patent/FI60389C/en active
- 1973-11-07 DE DE2355540A patent/DE2355540C2/en not_active Expired
- 1973-11-07 GB GB2395076A patent/GB1456513A/en not_active Expired
- 1973-11-07 DD DD182497*A patent/DD117233A5/xx unknown
- 1973-11-08 HU HU72PI00000399A patent/HU172703B/en unknown
- 1973-11-08 CS CS7500006065A patent/CS182793B2/en unknown
- 1973-11-08 HU HU73PI451A patent/HU173507B/en unknown
- 1973-11-08 HU HU73PI00000452A patent/HU171819B/en unknown
- 1973-11-08 CS CS7300007669A patent/CS182791B2/en unknown
- 1973-11-08 CS CS7500006066A patent/CS182794B2/en unknown
- 1973-11-11 SU SU7301971722A patent/SU584766A3/en active
-
1974
- 1974-06-06 AR AR254090A patent/AR202931A1/en active
- 1974-06-06 AR AR254091A patent/AR199966A1/en active
- 1974-09-26 NO NO743493A patent/NO148998C/en unknown
- 1974-12-18 ES ES433046A patent/ES433046A1/en not_active Expired
- 1974-12-18 ES ES433047A patent/ES433047A1/en not_active Expired
-
1975
- 1975-02-18 NO NO750535A patent/NO149139C/en unknown
- 1975-02-18 SU SU752106791A patent/SU667141A3/en active
- 1975-02-19 SU SU752106125A patent/SU893130A3/en active
- 1975-07-24 PH PH17410A patent/PH13110A/en unknown
- 1975-07-24 PH PH17409A patent/PH13325A/en unknown
- 1975-08-22 FR FR7526060A patent/FR2283146A1/en active Granted
- 1975-08-22 FR FR7526059A patent/FR2279729A1/en active Granted
-
1976
- 1976-07-23 AT AT544576A patent/AT360672B/en not_active IP Right Cessation
- 1976-07-23 AT AT544676A patent/AT353285B/en active
- 1976-10-15 JP JP51123737A patent/JPS5253841A/en active Pending
- 1976-10-15 JP JP51123738A patent/JPS5257147A/en active Pending
-
1977
- 1977-01-24 SE SE7700717A patent/SE436278B/en not_active IP Right Cessation
- 1977-01-24 SE SE7700716A patent/SE445111B/en not_active IP Right Cessation
- 1977-01-24 SE SE7700718A patent/SE431756B/en not_active IP Right Cessation
- 1977-07-11 CA CA341,897A patent/CA1088930A/en not_active Expired
- 1977-07-11 CA CA341,898A patent/CA1088931A/en not_active Expired
-
1978
- 1978-07-27 SU SU782629453A patent/SU745362A3/en active
-
1979
- 1979-03-15 KE KE2930A patent/KE2930A/en unknown
- 1979-03-15 KE KE2932A patent/KE2932A/en unknown
- 1979-03-15 KE KE2931A patent/KE2931A/en unknown
- 1979-05-03 HK HK281/79A patent/HK28179A/en unknown
- 1979-05-03 HK HK280/79A patent/HK28079A/en unknown
- 1979-05-03 HK HK279/79A patent/HK27979A/en unknown
- 1979-12-30 MY MY246/79A patent/MY7900246A/en unknown
- 1979-12-30 MY MY245/79A patent/MY7900245A/en unknown
- 1979-12-30 MY MY243/79A patent/MY7900243A/en unknown
-
1980
- 1980-10-23 YU YU2706/80A patent/YU37316B/en unknown
- 1980-10-23 YU YU2707/80A patent/YU36975B/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 |