AU470375B2 - Substituted w-pentanorprostaglandins - Google Patents

Substituted w-pentanorprostaglandins

Info

Publication number
AU470375B2
AU470375B2 AU62247/73A AU6224773A AU470375B2 AU 470375 B2 AU470375 B2 AU 470375B2 AU 62247/73 A AU62247/73 A AU 62247/73A AU 6224773 A AU6224773 A AU 6224773A AU 470375 B2 AU470375 B2 AU 470375B2
Authority
AU
Australia
Prior art keywords
pentanorprostaglandins
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU62247/73A
Other versions
AU6224773A (en
Inventor
SINGH BINDRA and MICHAEL ROSS JOHNSON JAGJIT
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US30481372A priority Critical
Priority to USUS304813 priority
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of AU6224773A publication Critical patent/AU6224773A/en
Application granted granted Critical
Publication of AU470375B2 publication Critical patent/AU470375B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
AU62247/73A 1972-11-08 1973-11-07 Substituted w-pentanorprostaglandins Expired AU470375B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US30481372A true 1972-11-08 1972-11-08
USUS304813 1972-11-08

Publications (2)

Publication Number Publication Date
AU6224773A AU6224773A (en) 1975-05-08
AU470375B2 true AU470375B2 (en) 1976-03-11

Family

ID=23178133

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62247/73A Expired AU470375B2 (en) 1972-11-08 1973-11-07 Substituted w-pentanorprostaglandins

Country Status (29)

Country Link
JP (3) JPS5416491B2 (en)
AR (3) AR200585A1 (en)
AT (3) AT367034B (en)
AU (1) AU470375B2 (en)
BE (1) BE806995A (en)
CA (3) CA1085831A (en)
CH (1) CH597176A5 (en)
CS (3) CS182793B2 (en)
DD (4) DD118856A5 (en)
DE (2) DE2355540C2 (en)
DK (1) DK144247C (en)
ES (3) ES420325A1 (en)
FI (1) FI60389C (en)
FR (3) FR2205335B1 (en)
GB (3) GB1456514A (en)
HK (3) HK28179A (en)
HU (3) HU171819B (en)
IE (1) IE39537B1 (en)
IL (1) IL43589A (en)
IN (1) IN139384B (en)
KE (3) KE2931A (en)
MY (3) MY7900246A (en)
NL (1) NL164273C (en)
NO (3) NO147836C (en)
PH (3) PH13272A (en)
SE (4) SE448992B (en)
SU (4) SU584766A3 (en)
YU (3) YU39715B (en)
ZA (1) ZA7308554B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
US3986764A (en) * 1975-03-31 1976-10-19 Gte Automatic Electric Laboratories Incorporated Panel for supporting a pair of elongated mating connectors and selectively locking them together
ES449162A1 (en) * 1975-06-23 1977-12-16 Syntex Inc 16-Phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
SE7809008L (en) * 1977-12-12 1979-06-13 Upjohn Co USE OF PROSTAGLAND TYPE AMIDES TO CONTROL OR REGULATE THE REPRODUCTION CYCLE IN INDIVIDUALS OF MAMMALS
IN150279B (en) * 1978-01-16 1982-09-04 Pfizer
HU0004427A3 (en) * 1997-09-09 2001-09-28 Procter & Gamble Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
AU766163B2 (en) 1999-03-05 2003-10-09 Duke University C16 unsaturated fp-selective prostaglandins analogs
US6894175B1 (en) 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
JP2002329615A (en) * 2001-05-02 2002-11-15 Ohira Denshi Kk Toroidal coil
US6476064B1 (en) * 2001-06-13 2002-11-05 Allergan, Inc. Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents
JP2008517941A (en) 2004-10-21 2008-05-29 デューク・ユニバーシティー Ophthalmic drugs
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE37602B1 (en) * 1971-05-11 1977-08-31 Ici Ltd Cyclopentane derivatives
GB1324737A (en) * 1970-11-02 1973-07-25 Upjohn Co Prostaglandins and the preparation thereof

Also Published As

Publication number Publication date
YU288073A (en) 1982-02-28
FR2283146A1 (en) 1976-03-26
IL43589A (en) 1980-01-31
DD119411A5 (en) 1976-04-20
IE39537B1 (en) 1978-11-08
PH13110A (en) 1979-11-28
SE7700716L (en) 1977-01-24
BE806995A (en) 1974-05-07
PH13325A (en) 1980-03-13
MY7900246A (en) 1979-12-31
NO148998B (en) 1983-10-17
SU584766A3 (en) 1977-12-15
DE2365322A1 (en) 1974-11-07
SE448992B (en) 1987-03-30
ES433046A1 (en) 1977-06-16
ES420325A1 (en) 1976-04-16
DK144247C (en) 1982-07-12
NO743493L (en) 1974-05-09
NO149139C (en) 1984-02-29
CS182794B2 (en) 1978-05-31
YU270680A (en) 1983-04-27
CA1085831A (en) 1980-09-16
IN139384B (en) 1976-06-12
SE445111B (en) 1986-06-02
FR2279729B1 (en) 1978-04-28
JPS5257147A (en) 1977-05-11
FR2279729A1 (en) 1976-02-20
YU36975B (en) 1984-08-31
HU171819B (en) 1978-03-28
MY7900245A (en) 1979-12-31
HK28079A (en) 1979-05-11
SE431756B (en) 1984-02-27
DE2365322B2 (en) 1977-02-24
ZA7308554B (en) 1974-09-25
FI60389B (en) 1981-09-30
DD118856A5 (en) 1976-03-20
JPS4993342A (en) 1974-09-05
KE2930A (en) 1979-03-30
AR202931A1 (en) 1975-07-31
ATA544676A (en) 1979-04-15
YU270780A (en) 1982-06-18
JPS5416491B2 (en) 1979-06-22
NO147836B (en) 1983-03-14
CS182791B2 (en) 1978-05-31
YU37316B (en) 1984-08-31
PH13272A (en) 1980-02-27
NO148998C (en) 1984-01-25
DD117233A5 (en) 1976-01-05
NO750535L (en) 1974-05-09
SE7700718L (en) 1977-01-24
DE2355540A1 (en) 1974-05-22
IE39537L (en) 1974-05-08
IL43589D0 (en) 1974-03-14
HU173507B (en) 1979-05-28
CA1085831A1 (en)
AT367034B (en) 1982-05-25
KE2932A (en) 1979-03-30
NO147836C (en) 1983-06-22
KE2931A (en) 1979-03-30
SU667141A3 (en) 1979-06-05
SU745362A3 (en) 1980-06-30
HK27979A (en) 1979-05-11
SU893130A3 (en) 1981-12-23
SE7700717L (en) 1977-01-24
CA1088930A (en) 1980-11-04
NL7315263A (en) 1974-05-10
AR199966A1 (en) 1974-10-08
SE436278B (en) 1984-11-26
GB1456514A (en) 1976-11-24
CH597176A5 (en) 1978-03-31
NL164273C (en) 1980-12-15
FI60389C (en) 1982-01-11
CS182793B2 (en) 1978-05-31
BE806995A1 (en)
CA1088931A (en) 1980-11-04
MY7900243A (en) 1979-12-31
FR2283146B1 (en) 1981-06-19
JPS5253841A (en) 1977-04-30
AR200585A1 (en) 1974-11-22
ES433047A1 (en) 1976-11-01
HU172703B (en) 1978-11-28
HK28179A (en) 1979-05-11
ATA936973A (en) 1981-10-15
CA1088930A2 (en)
CA1088931A2 (en)
NO149139B (en) 1983-11-14
YU39715B (en) 1985-04-30
AT360672B (en) 1981-01-26
FR2205335A1 (en) 1974-05-31
DK144247B (en) 1982-01-25
GB1456512A (en) 1976-11-24
DD109212A5 (en) 1974-10-20
GB1456513A (en) 1976-11-24
FR2205335B1 (en) 1978-07-13
AT353285B (en) 1979-11-12
ATA544576A (en) 1980-06-15
AU6224773A (en) 1975-05-08
DE2355540C2 (en) 1982-11-18

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