NL158176B - PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH (BETA) ADDRENERGIC BLOCKING ACTION, FORMED MEDICINAL PRODUCT OBTAINED UNDER APPLICATION THEREOF, AND PROCESS FOR PREPARING A COMPOUND SUITABLE FOR USE FOR USE. - Google Patents

PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH (BETA) ADDRENERGIC BLOCKING ACTION, FORMED MEDICINAL PRODUCT OBTAINED UNDER APPLICATION THEREOF, AND PROCESS FOR PREPARING A COMPOUND SUITABLE FOR USE FOR USE.

Info

Publication number
NL158176B
NL158176B NL7302353.A NL7302353A NL158176B NL 158176 B NL158176 B NL 158176B NL 7302353 A NL7302353 A NL 7302353A NL 158176 B NL158176 B NL 158176B
Authority
NL
Netherlands
Prior art keywords
preparing
medicinal product
addrenergic
beta
obtained under
Prior art date
Application number
NL7302353.A
Other languages
Dutch (nl)
Other versions
NL7302353A (en
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP47092560A external-priority patent/JPS5246231B2/ja
Priority claimed from JP9255772A external-priority patent/JPS5324431B2/ja
Priority claimed from JP47092558A external-priority patent/JPS5241268B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NL7302353A publication Critical patent/NL7302353A/xx
Publication of NL158176B publication Critical patent/NL158176B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL7302353.A 1972-04-13 1973-02-20 PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH (BETA) ADDRENERGIC BLOCKING ACTION, FORMED MEDICINAL PRODUCT OBTAINED UNDER APPLICATION THEREOF, AND PROCESS FOR PREPARING A COMPOUND SUITABLE FOR USE FOR USE. NL158176B (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP47037182A JPS48103590A (en) 1972-04-13 1972-04-13
JP47037181A JPS517672B2 (en) 1972-04-13 1972-04-13
JP47092560A JPS5246231B2 (en) 1972-09-14 1972-09-14
JP9255772A JPS5324431B2 (en) 1972-09-14 1972-09-14
JP47092558A JPS5241268B2 (en) 1972-09-14 1972-09-14
JP47120953A JPS5229745B2 (en) 1972-04-13 1972-12-02
JP47125858A JPS5239036B2 (en) 1972-04-13 1972-12-14
JP47128972A JPS5241269B2 (en) 1972-04-13 1972-12-21

Publications (2)

Publication Number Publication Date
NL7302353A NL7302353A (en) 1973-10-16
NL158176B true NL158176B (en) 1978-10-16

Family

ID=27572212

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7302353.A NL158176B (en) 1972-04-13 1973-02-20 PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH (BETA) ADDRENERGIC BLOCKING ACTION, FORMED MEDICINAL PRODUCT OBTAINED UNDER APPLICATION THEREOF, AND PROCESS FOR PREPARING A COMPOUND SUITABLE FOR USE FOR USE.

Country Status (17)

Country Link
JP (5) JPS517672B2 (en)
AR (1) AR209575A1 (en)
AU (1) AU475964B2 (en)
BE (1) BE794669A (en)
CA (1) CA1025447A (en)
CH (1) CH575929A5 (en)
DD (2) DD112446A5 (en)
DE (1) DE2302027C2 (en)
DK (1) DK141603B (en)
FI (1) FI53703C (en)
FR (1) FR2179715B1 (en)
GB (2) GB1424572A (en)
HK (1) HK19481A (en)
NL (1) NL158176B (en)
NO (1) NO140589C (en)
SE (1) SE380018B (en)
YU (1) YU41187B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5082218A (en) * 1973-11-10 1975-07-03
US4022784A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives
US4137331A (en) 1974-06-19 1979-01-30 Sandoz Ltd. 3-Piperidino-2-hydroxypropoxy substituted-2-indolinones
JPS516971A (en) * 1974-07-08 1976-01-20 Otsuka Pharma Co Ltd Nitoro 3*44 jihidorokarubosuchirirujudotaino seizoho
JPS5129486A (en) * 1974-09-02 1976-03-12 Otsuka Pharma Co Ltd * 33 arukiruamino 22 hidorokishi * purohokishi 3 44 jihidorokarubosuchirirujudotai no seizoho
JPS5148674A (en) * 1974-10-17 1976-04-26 Otsuka Pharma Co Ltd 3 44 jihidorokarubosuchirirujudotaino seizoho
JPS5152180A (en) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd KARUBOSUCHIRIRU JUDOTAINO SEIZOHO
JPS5152178A (en) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd KARUBOSUCHIRIRU JUDOTAINO SEIZOHO
JPS5152179A (en) * 1974-10-31 1976-05-08 Otsuka Pharma Co Ltd KARUBOSUCHIRIRU JUDOTAINO SEIZOHO
FI58329C (en) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd PROCEDURE FOR FRAMSTATION OF I 8-STATIONARY SUBSTITUTES 5- (3'-ALKYLAMINO-2'-HYDROXY) PROPOXI-3,4-DIHYDROCARBOSTYRILDER
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH619453A5 (en) * 1976-03-17 1980-09-30 Otsuka Pharma Co Ltd
DE2719562C2 (en) * 1976-05-08 1986-05-07 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo 3, 4-Dihydrocarbostyril derivatives, processes for their preparation and pharmaceuticals containing them
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
DE2960178D1 (en) * 1978-06-06 1981-04-09 Hoechst Ag New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation
DE2827566A1 (en) * 1978-06-23 1980-01-10 Boehringer Mannheim Gmbh 1,2-DIHYDRO-CHINOLIN-2-ON DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
AU518814B2 (en) * 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
DE3034237A1 (en) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo CARBOSTYRIL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND ANTIHISTAMINICALLY ACTIVE AGENTS CONTAINING THESE COMPOUNDS
JPS56122356A (en) * 1980-02-29 1981-09-25 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS58103343A (en) * 1981-12-15 1983-06-20 Ota Seiyaku Kk Preparation of propanolamine compound
JPS597186A (en) * 1982-07-02 1984-01-14 Ota Seiyaku Kk 1,3,2-dioxathiolane 2-oxide derivative
JPS63193086U (en) * 1987-05-30 1988-12-13
DE3808136A1 (en) * 1988-03-11 1989-09-21 Thomae Gmbh Dr K DRUGS CONTAINING CHINOLINE-2,5-DIONE, NEW CHINOLINE-2,5-DIONE AND METHOD OF PREPARING THEM
DE68920797T2 (en) * 1988-08-10 1995-06-29 Otsuka Pharma Co Ltd Heart medication.
US5266577A (en) * 1988-08-10 1993-11-30 Otsuka Pharmaceutical Company Ltd. Method of treating congestive heart failure using carbostyril derivatives
CA2093633A1 (en) * 1991-08-23 1993-02-24 Seiji Sato Carbostyril derivative and platelets aggregation inhibitory agent
ES2048108B1 (en) * 1992-07-17 1994-10-01 Lusochimica Spa PROCEDURE FOR THE PREPARATION OF 5- (3-TERC-BUTILAMINO-2-HIDROXIPROPOXI) -3,4-DIHIDROCARBOESTIRILO.
IT1264816B1 (en) * 1993-07-28 1996-10-10 Pergam Srl Process for the preparation of 3,4-dihydrocarbostyryl derivatives
CZ300351B6 (en) * 2005-05-26 2009-04-29 Zentiva, A. S. Process for preparing 7-hydroxy-3,4-dihydrocarbostyril

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
CH514611A (en) * 1968-07-05 1971-10-31 Cassella Farbwerke Mainkur Ag Process for the preparation of derivatives of 2-oxo-1,2-dihydro-quinoline

Also Published As

Publication number Publication date
JPS4976878A (en) 1974-07-24
NL7302353A (en) 1973-10-16
JPS517672B2 (en) 1976-03-10
JPS5229745B2 (en) 1977-08-03
BE794669A (en) 1973-05-16
GB1424571A (en) 1976-02-11
FI53703C (en) 1978-07-10
CH575929A5 (en) 1976-05-31
DD108293A5 (en) 1974-09-12
YU254979A (en) 1982-10-31
NO140589B (en) 1979-06-25
JPS48103590A (en) 1973-12-25
AU5438673A (en) 1974-10-17
AU475964B2 (en) 1976-09-09
DK141603C (en) 1980-10-06
HK19481A (en) 1981-05-22
DE2302027C2 (en) 1983-03-17
FR2179715A1 (en) 1973-11-23
JPS5241269B2 (en) 1977-10-17
FI53703B (en) 1978-03-31
FR2179715B1 (en) 1976-12-03
DE2302027A1 (en) 1973-12-06
AR209575A1 (en) 1977-05-13
JPS4981373A (en) 1974-08-06
SE380018B (en) 1975-10-27
YU41187B (en) 1986-12-31
GB1424572A (en) 1976-02-11
JPS5239036B2 (en) 1977-10-03
DD112446A5 (en) 1975-04-12
JPS48103589A (en) 1973-12-25
CA1025447A (en) 1978-01-31
DK141603B (en) 1980-05-05
NO140589C (en) 1979-10-03
JPS4982673A (en) 1974-08-08

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Legal Events

Date Code Title Description
NL80 Abbreviated name of patent owner mentioned of already nullified patent

Owner name: OTSUKA PHARM

V4 Lapsed because of reaching the maximum lifetime of a patent