JPS5416478A - 3,4-dihydrocarbostyril herivative - Google Patents

3,4-dihydrocarbostyril herivative

Info

Publication number
JPS5416478A
JPS5416478A JP8236577A JP8236577A JPS5416478A JP S5416478 A JPS5416478 A JP S5416478A JP 8236577 A JP8236577 A JP 8236577A JP 8236577 A JP8236577 A JP 8236577A JP S5416478 A JPS5416478 A JP S5416478A
Authority
JP
Japan
Prior art keywords
dihydrocarbostyril
herivative
alkyl
japio
jpo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8236577A
Other versions
JPS5760337B2 (en
Inventor
Takafumi Fujioka
Kazuyuki Nakagawa
Kazuhisa Sakano
Original Assignee
Otsuka Pharmaceut Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceut Co Ltd filed Critical Otsuka Pharmaceut Co Ltd
Priority to JP52082365A priority Critical patent/JPS5760337B2/ja
Publication of JPS5416478A publication Critical patent/JPS5416478A/en
Publication of JPS5760337B2 publication Critical patent/JPS5760337B2/ja
Expired legal-status Critical Current

Links

Abstract

PURPOSE: 3,4-Dihydrocarbostyril derivatives of formula I [R1 is H, lower alkyl; R2, R3 are H, alkyl or phenyl-substituted alkyl, R2, R3 may form 6-membered saturated heterocyclic ring together with N atom; A is -CO-, -CH(OH)-; X is halogen].
COPYRIGHT: (C)1979,JPO&Japio
JP52082365A 1977-07-08 1977-07-08 Expired JPS5760337B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP52082365A JPS5760337B2 (en) 1977-07-08 1977-07-08

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52082365A JPS5760337B2 (en) 1977-07-08 1977-07-08

Publications (2)

Publication Number Publication Date
JPS5416478A true JPS5416478A (en) 1979-02-07
JPS5760337B2 JPS5760337B2 (en) 1982-12-18

Family

ID=13772547

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52082365A Expired JPS5760337B2 (en) 1977-07-08 1977-07-08

Country Status (1)

Country Link
JP (1) JPS5760337B2 (en)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56125370A (en) * 1980-03-06 1981-10-01 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS57136517A (en) * 1981-02-17 1982-08-23 Otsuka Pharmaceut Co Ltd Cardiotonic
US4348398A (en) * 1980-12-23 1982-09-07 Merck Sharp & Dohme (I.A.) Corp. Quinolinyl ethanolamines
DE3204892A1 (en) * 1981-02-17 1982-09-23 Otsuka Pharma Co Ltd Carbostyrile derivatives, method for the production thereof, and cardiotonic compositions that contain them
FR2512019A1 (en) * 1981-09-01 1983-03-04 Otsuka Pharma Co Ltd Carbosyryl derivatives, processes for their preparation and therapeutic composition containing same
JPS5838258A (en) * 1981-09-01 1983-03-05 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS5843952A (en) * 1981-09-09 1983-03-14 Otsuka Pharmaceut Co Ltd Preparation of carbostyril derivative
US4455422A (en) * 1980-03-06 1984-06-19 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and pharmaceutical composition containing the same
US4482560A (en) * 1979-09-18 1984-11-13 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives, and antihistaminic agents containing the same
US4810712A (en) * 1984-09-19 1989-03-07 Beiersdorf Ag Bicyclic lactams, processes for their use, and formulations containing these compounds
US4886809A (en) * 1986-07-31 1989-12-12 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof
JPH0249769A (en) * 1989-06-26 1990-02-20 Otsuka Pharmaceut Co Ltd Carbostyril derivative
US5591751A (en) * 1993-02-16 1997-01-07 Otsuka Pharmaceutical Co., Ltd. Peripheral vasodilators
US5656642A (en) * 1993-04-07 1997-08-12 Otsuka Pharmaceutical Co., Ltd. Peripheral vasodilating agent containing piperidine derivative as active ingredient
WO2004050657A3 (en) * 2002-11-27 2004-11-25 Artesian Therapeutics Inc COMPOUNDS WITH MIXED PDE-INHIBITORY AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE
GB2403655A (en) * 2003-07-11 2005-01-12 Cipla Ltd Combined pharmaceutical product comprising a beta-2 adrenoreceptor agonist & an antihistamine for treatment of respiratory diseases such as asthma
US8445516B2 (en) 2004-01-29 2013-05-21 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical composition for promoting angiogenesis

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482560A (en) * 1979-09-18 1984-11-13 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives, and antihistaminic agents containing the same
US4455422A (en) * 1980-03-06 1984-06-19 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and pharmaceutical composition containing the same
DK155282B (en) * 1980-03-06 1989-03-20 Otsuka Pharma Co Ltd Analogy procedure for the preparation of carbostyric derivatives
JPS6325585B2 (en) * 1980-03-06 1988-05-26 Otsuka Pharma Co Ltd
US4567187A (en) * 1980-03-06 1986-01-28 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and antihistaminic agents containing the carbostyril derivatives
JPS56125370A (en) * 1980-03-06 1981-10-01 Otsuka Pharmaceut Co Ltd Carbostyril derivative
US4348398A (en) * 1980-12-23 1982-09-07 Merck Sharp & Dohme (I.A.) Corp. Quinolinyl ethanolamines
US4487772A (en) * 1981-02-17 1984-12-11 Otsuka Pharmaceutical Co. Ltd. Carbostyril derivatives and their salts
DE3204892A1 (en) * 1981-02-17 1982-09-23 Otsuka Pharma Co Ltd Carbostyrile derivatives, method for the production thereof, and cardiotonic compositions that contain them
JPS57136517A (en) * 1981-02-17 1982-08-23 Otsuka Pharmaceut Co Ltd Cardiotonic
JPS5838258A (en) * 1981-09-01 1983-03-05 Otsuka Pharmaceut Co Ltd Carbostyril derivative
FR2512019A1 (en) * 1981-09-01 1983-03-04 Otsuka Pharma Co Ltd Carbosyryl derivatives, processes for their preparation and therapeutic composition containing same
US4514401A (en) * 1981-09-01 1985-04-30 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
JPH0143746B2 (en) * 1981-09-09 1989-09-22 Otsuka Pharma Co Ltd
JPS5843952A (en) * 1981-09-09 1983-03-14 Otsuka Pharmaceut Co Ltd Preparation of carbostyril derivative
US4810712A (en) * 1984-09-19 1989-03-07 Beiersdorf Ag Bicyclic lactams, processes for their use, and formulations containing these compounds
US4886809A (en) * 1986-07-31 1989-12-12 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof
JPH0249769A (en) * 1989-06-26 1990-02-20 Otsuka Pharmaceut Co Ltd Carbostyril derivative
US5591751A (en) * 1993-02-16 1997-01-07 Otsuka Pharmaceutical Co., Ltd. Peripheral vasodilators
US5656642A (en) * 1993-04-07 1997-08-12 Otsuka Pharmaceutical Co., Ltd. Peripheral vasodilating agent containing piperidine derivative as active ingredient
US5760058A (en) * 1993-04-07 1998-06-02 Otsuka Pharmaceutical Co., Ltd. Peripheral vasodilating agent containing piperidine derivative as active ingredient
WO2004050657A3 (en) * 2002-11-27 2004-11-25 Artesian Therapeutics Inc COMPOUNDS WITH MIXED PDE-INHIBITORY AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE
JP2006509790A (en) * 2002-11-27 2006-03-23 アルテシアン セラピューティック,インコーポレイティド Compounds with mixed PDE inhibition and beta-adrenergic antagonist activity or partial agonist activity for the treatment of heart failure
GB2403655A (en) * 2003-07-11 2005-01-12 Cipla Ltd Combined pharmaceutical product comprising a beta-2 adrenoreceptor agonist & an antihistamine for treatment of respiratory diseases such as asthma
US8445516B2 (en) 2004-01-29 2013-05-21 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical composition for promoting angiogenesis

Also Published As

Publication number Publication date
JPS5760337B2 (en) 1982-12-18

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