JPS55138396A - Production of cephalosporin analogs - Google Patents
Production of cephalosporin analogsInfo
- Publication number
- JPS55138396A JPS55138396A JP4589779A JP4589779A JPS55138396A JP S55138396 A JPS55138396 A JP S55138396A JP 4589779 A JP4589779 A JP 4589779A JP 4589779 A JP4589779 A JP 4589779A JP S55138396 A JPS55138396 A JP S55138396A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- microorganism
- analogs
- hydrogens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE:Optically active cephalosporin analogs or their salts are produced by use of the culture mixture of a specific microorganism or it processed product. CONSTITUTION:The reaction between a compound of formula II (R1 is residue of six-membered carbon cyclic group, five-membered heterocyclic group; X is H, hydroxyl, alkyl, carboxyl, amino) or its reactive derivative and another compound of formula III (R2 is H, alkyl; R3 is H, ester residue; the hydrogens in the 6 and 7 positions are in cis configuration) is conducted in the presence of a microorganism that belongs to Pseudomonas, Xanthomonas, and others and can produce optically active cephalosporine analogs of formula I (each R and X is the same as the above; the hydrogens in the 6 and 7 positions are in cis) from a compound of formula II or its reactive derivative and another compound of formula III, its culture mixture, or its processed product or the enzyme produced by the microorganism.
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4589779A JPS55138396A (en) | 1979-04-14 | 1979-04-14 | Production of cephalosporin analogs |
| NO800315A NO155548C (en) | 1979-02-10 | 1980-02-06 | PROCEDURE FOR THE PREPARATION OF OPTICALLY ACTIVE CEPHALOSPORIN ANALOGS. |
| CA000345348A CA1171373A (en) | 1979-02-10 | 1980-02-07 | Optically active cephalosporin analogs |
| ES488428A ES8101591A1 (en) | 1979-02-10 | 1980-02-08 | A procedure for the preparation of cefalosporine analogues. (Machine-translation by Google Translate, not legally binding) |
| DE8080100666T DE3064509D1 (en) | 1979-02-10 | 1980-02-08 | Optically active acylated cephalosporin analogs, processes for their preparation and pharmaceutical compositions comprising them |
| AU55382/80A AU5538280A (en) | 1979-02-10 | 1980-02-08 | 1-azabicyclo (4,2,0) oct-2-em derivatives |
| DK054880A DK170255B1 (en) | 1979-02-10 | 1980-02-08 | Analogous Process for Preparation of Optically Active Cephalosporin Analogs |
| EP80100666A EP0014476B1 (en) | 1979-02-10 | 1980-02-08 | Optically active acylated cephalosporin analogs, processes for their preparation and pharmaceutical compositions comprising them |
| US06/140,184 US4332896A (en) | 1979-04-14 | 1980-04-14 | Process for producing cephalosporin analogs |
| ES495037A ES495037A0 (en) | 1979-02-10 | 1980-09-12 | A PROCEDURE FOR THE PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS OF CEPHALOSPORIN ANALOGS |
| NO841499A NO841499L (en) | 1979-02-10 | 1984-04-13 | PROCEDURE FOR THE PREPARATION OF OPTICALLY ACTIVE CEPHALOSPORIN ANALOGUE |
| MX9203636A MX9203636A (en) | 1979-02-10 | 1992-06-26 | ANALOG COMPOUNDS OF CEPHALOSPORIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4589779A JPS55138396A (en) | 1979-04-14 | 1979-04-14 | Production of cephalosporin analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS55138396A true JPS55138396A (en) | 1980-10-29 |
Family
ID=12732027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4589779A Pending JPS55138396A (en) | 1979-02-10 | 1979-04-14 | Production of cephalosporin analogs |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55138396A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4640919A (en) * | 1984-02-21 | 1987-02-03 | Kyowa Hakko Kogyo Co., Ltd. | 3-substituted carbacepem compounds having antibacterial effect |
-
1979
- 1979-04-14 JP JP4589779A patent/JPS55138396A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4640919A (en) * | 1984-02-21 | 1987-02-03 | Kyowa Hakko Kogyo Co., Ltd. | 3-substituted carbacepem compounds having antibacterial effect |
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