DK152357C - Fremgangsmaade til fremstilling af optisk aktive anthracyclinoner - Google Patents

Fremgangsmaade til fremstilling af optisk aktive anthracyclinoner

Info

Publication number
DK152357C
DK152357C DK265977A DK265977A DK152357C DK 152357 C DK152357 C DK 152357C DK 265977 A DK265977 A DK 265977A DK 265977 A DK265977 A DK 265977A DK 152357 C DK152357 C DK 152357C
Authority
DK
Denmark
Prior art keywords
anthracyclinons
procedure
preparation
optically active
optically
Prior art date
Application number
DK265977A
Other languages
English (en)
Other versions
DK152357B (da
DK265977A (da
Inventor
Luigi Bernardi
Pietro Giardino
Bianca Patelli
Federico Arcamone
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of DK265977A publication Critical patent/DK265977A/da
Publication of DK152357B publication Critical patent/DK152357B/da
Application granted granted Critical
Publication of DK152357C publication Critical patent/DK152357C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00Quinones
    • C07C50/26Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/36Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
DK265977A 1976-06-19 1977-06-16 Fremgangsmaade til fremstilling af optisk aktive anthracyclinoner DK152357C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2551776 1976-06-19
GB25517/76A GB1527050A (en) 1976-06-19 1976-06-19 Optically active anthracyclinones

Publications (3)

Publication Number Publication Date
DK265977A DK265977A (da) 1977-12-20
DK152357B DK152357B (da) 1988-02-22
DK152357C true DK152357C (da) 1988-09-12

Family

ID=10228981

Family Applications (1)

Application Number Title Priority Date Filing Date
DK265977A DK152357C (da) 1976-06-19 1977-06-16 Fremgangsmaade til fremstilling af optisk aktive anthracyclinoner

Country Status (14)

Country Link
US (1) US4132721A (da)
JP (1) JPS6058213B2 (da)
AT (1) AT347445B (da)
AU (1) AU511513B2 (da)
BE (1) BE855795A (da)
CA (1) CA1076561A (da)
CH (1) CH629743A5 (da)
DE (1) DE2727341C3 (da)
DK (1) DK152357C (da)
FR (1) FR2354990A1 (da)
GB (1) GB1527050A (da)
NL (1) NL175616C (da)
SE (1) SE440500B (da)
ZA (1) ZA773644B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215062A (en) * 1978-05-22 1980-07-29 University Of Kansas Endowment Association Anthracycline synthesis
JPS54160356A (en) * 1978-06-05 1979-12-19 Univ Kansas State Synthesis of tetrahydronaphthalene
GB2056443B (en) * 1979-08-20 1984-01-18 Hoffmann La Roche Cyclic compounds
JPS5756494A (en) * 1980-09-22 1982-04-05 Microbial Chem Res Found New anthracyclin derivative
US4374979A (en) * 1981-04-27 1983-02-22 The University Of Kansas Endowment Association Regiospecific synthesis of anthracyclinone compounds such as daunomycinone
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) * 1988-04-11 1988-05-11 Erba Carlo Spa Process for preparing 4-demethoxydauno-mycinone
DE10155016A1 (de) * 2001-11-07 2003-05-15 Knoell Hans Forschung Ev Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3201424A (en) * 1962-10-29 1965-08-17 American Cyanamid Co Derivatives of 1, 3, 11, 12-tetrahydroxynaphthacene and 1, 3, 6, 11-tetrahydroxynaphtacene-5, 12-quinone
GB1461190A (en) * 1974-09-20 1977-01-13 Farmaceutici Italia Anthracycline preparation
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4070382A (en) * 1975-11-18 1978-01-24 Research Corporation Intermediates for polycyclic quinoid antibiotics
US4012448A (en) * 1976-01-15 1977-03-15 Stanford Research Institute Synthesis of adriamycin and 7,9-epiadriamycin

Also Published As

Publication number Publication date
NL175616B (nl) 1984-07-02
DE2727341B2 (de) 1981-10-08
NL7706471A (nl) 1977-12-21
GB1527050A (en) 1978-10-04
FR2354990A1 (fr) 1978-01-13
SE7707037L (sv) 1977-12-19
DK152357B (da) 1988-02-22
AT347445B (de) 1978-12-27
DE2727341A1 (de) 1977-12-22
ATA427577A (de) 1978-05-15
JPS6058213B2 (ja) 1985-12-19
NL175616C (nl) 1984-12-03
US4132721A (en) 1979-01-02
CA1076561A (en) 1980-04-29
AU2609877A (en) 1978-12-21
AU511513B2 (en) 1980-08-21
DK265977A (da) 1977-12-20
JPS52156852A (en) 1977-12-27
BE855795A (fr) 1977-12-19
ZA773644B (en) 1978-05-30
SE440500B (sv) 1985-08-05
CH629743A5 (de) 1982-05-14
FR2354990B1 (da) 1983-07-29
DE2727341C3 (de) 1982-05-06

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Legal Events

Date Code Title Description
PUP Patent expired