SE440500B - Forfarande for framstellning av optiskt aktiva antracyklinoner - Google Patents

Forfarande for framstellning av optiskt aktiva antracyklinoner

Info

Publication number
SE440500B
SE440500B SE7707037A SE7707037A SE440500B SE 440500 B SE440500 B SE 440500B SE 7707037 A SE7707037 A SE 7707037A SE 7707037 A SE7707037 A SE 7707037A SE 440500 B SE440500 B SE 440500B
Authority
SE
Sweden
Prior art keywords
anthracyclinons
procedure
preparation
optically active
optically
Prior art date
Application number
SE7707037A
Other languages
English (en)
Other versions
SE7707037L (sv
Inventor
L Bernardi
P Giardino
B Patelli
F Arcamone
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of SE7707037L publication Critical patent/SE7707037L/sv
Publication of SE440500B publication Critical patent/SE440500B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/36—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
SE7707037A 1976-06-19 1977-06-16 Forfarande for framstellning av optiskt aktiva antracyklinoner SE440500B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB25517/76A GB1527050A (en) 1976-06-19 1976-06-19 Optically active anthracyclinones

Publications (2)

Publication Number Publication Date
SE7707037L SE7707037L (sv) 1977-12-19
SE440500B true SE440500B (sv) 1985-08-05

Family

ID=10228981

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7707037A SE440500B (sv) 1976-06-19 1977-06-16 Forfarande for framstellning av optiskt aktiva antracyklinoner

Country Status (14)

Country Link
US (1) US4132721A (sv)
JP (1) JPS6058213B2 (sv)
AT (1) AT347445B (sv)
AU (1) AU511513B2 (sv)
BE (1) BE855795A (sv)
CA (1) CA1076561A (sv)
CH (1) CH629743A5 (sv)
DE (1) DE2727341C3 (sv)
DK (1) DK152357C (sv)
FR (1) FR2354990A1 (sv)
GB (1) GB1527050A (sv)
NL (1) NL175616C (sv)
SE (1) SE440500B (sv)
ZA (1) ZA773644B (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215062A (en) * 1978-05-22 1980-07-29 University Of Kansas Endowment Association Anthracycline synthesis
JPS54160356A (en) * 1978-06-05 1979-12-19 Univ Kansas State Synthesis of tetrahydronaphthalene
GB2056443B (en) * 1979-08-20 1984-01-18 Hoffmann La Roche Cyclic compounds
JPS5756494A (en) * 1980-09-22 1982-04-05 Microbial Chem Res Found New anthracyclin derivative
US4374979A (en) * 1981-04-27 1983-02-22 The University Of Kansas Endowment Association Regiospecific synthesis of anthracyclinone compounds such as daunomycinone
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) * 1988-04-11 1988-05-11 Erba Carlo Spa Process for preparing 4-demethoxydauno-mycinone
DE10155016A1 (de) * 2001-11-07 2003-05-15 Knoell Hans Forschung Ev Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3201424A (en) * 1962-10-29 1965-08-17 American Cyanamid Co Derivatives of 1, 3, 11, 12-tetrahydroxynaphthacene and 1, 3, 6, 11-tetrahydroxynaphtacene-5, 12-quinone
GB1461190A (en) * 1974-09-20 1977-01-13 Farmaceutici Italia Anthracycline preparation
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4070382A (en) * 1975-11-18 1978-01-24 Research Corporation Intermediates for polycyclic quinoid antibiotics
US4012448A (en) * 1976-01-15 1977-03-15 Stanford Research Institute Synthesis of adriamycin and 7,9-epiadriamycin

Also Published As

Publication number Publication date
JPS52156852A (en) 1977-12-27
AT347445B (de) 1978-12-27
AU511513B2 (en) 1980-08-21
CH629743A5 (de) 1982-05-14
FR2354990B1 (sv) 1983-07-29
FR2354990A1 (fr) 1978-01-13
US4132721A (en) 1979-01-02
JPS6058213B2 (ja) 1985-12-19
ATA427577A (de) 1978-05-15
DE2727341A1 (de) 1977-12-22
DK265977A (da) 1977-12-20
CA1076561A (en) 1980-04-29
SE7707037L (sv) 1977-12-19
NL175616C (nl) 1984-12-03
AU2609877A (en) 1978-12-21
DK152357B (da) 1988-02-22
DK152357C (da) 1988-09-12
NL7706471A (nl) 1977-12-21
GB1527050A (en) 1978-10-04
NL175616B (nl) 1984-07-02
ZA773644B (en) 1978-05-30
DE2727341C3 (de) 1982-05-06
DE2727341B2 (de) 1981-10-08
BE855795A (fr) 1977-12-19

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