KR850003290A - 5-치환된 옥사졸리딘-2, 4-디온의 제조방법 - Google Patents

5-치환된 옥사졸리딘-2, 4-디온의 제조방법

Info

Publication number
KR850003290A
KR850003290A KR1019840006723A KR840006723A KR850003290A KR 850003290 A KR850003290 A KR 850003290A KR 1019840006723 A KR1019840006723 A KR 1019840006723A KR 840006723 A KR840006723 A KR 840006723A KR 850003290 A KR850003290 A KR 850003290A
Authority
KR
South Korea
Prior art keywords
dione
producing
substituted oxazolidine
oxazolidine
substituted
Prior art date
Application number
KR1019840006723A
Other languages
English (en)
Other versions
KR850000382B1 (ko
Inventor
코흐렌 슈너 로드니
Original Assignee
화이자 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 화이자 인코포레이티드 filed Critical 화이자 인코포레이티드
Application granted granted Critical
Publication of KR850000382B1 publication Critical patent/KR850000382B1/ko
Publication of KR850003290A publication Critical patent/KR850003290A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/008—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with tri- or tetrahalomethyl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/546—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/55—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/46—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019840006723A 1980-07-28 1984-10-29 5-치환된 옥사졸리딘-2, 4-디온의 제조방법 KR850000382B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17320680A 1980-07-28 1980-07-28
US173,206 1980-07-28
US222,202 1981-01-02
US06/222,202 US4367234A (en) 1980-07-28 1981-01-02 Hypoglycemic 5-substituted oxazolidine-2,4-diones
KR1019810002716A KR850000381B1 (ko) 1980-07-28 1981-07-27 5-치환된 옥사졸리딘-2,-4디온의 제조방법

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002716A Division KR850000381B1 (ko) 1980-07-28 1981-07-27 5-치환된 옥사졸리딘-2,-4디온의 제조방법

Publications (2)

Publication Number Publication Date
KR850000382B1 KR850000382B1 (ko) 1985-03-23
KR850003290A true KR850003290A (ko) 1985-06-13

Family

ID=26868872

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1019810002716A KR850000381B1 (ko) 1980-07-28 1981-07-27 5-치환된 옥사졸리딘-2,-4디온의 제조방법
KR1019840006724A KR850000387B1 (ko) 1980-07-28 1984-10-29 5-치환된 옥사졸리딘-2, 4-디온의 제조방법
KR1019840006723A KR850000382B1 (ko) 1980-07-28 1984-10-29 5-치환된 옥사졸리딘-2, 4-디온의 제조방법

Family Applications Before (2)

Application Number Title Priority Date Filing Date
KR1019810002716A KR850000381B1 (ko) 1980-07-28 1981-07-27 5-치환된 옥사졸리딘-2,-4디온의 제조방법
KR1019840006724A KR850000387B1 (ko) 1980-07-28 1984-10-29 5-치환된 옥사졸리딘-2, 4-디온의 제조방법

Country Status (27)

Country Link
US (1) US4367234A (ko)
KR (3) KR850000381B1 (ko)
AR (3) AR228061A1 (ko)
AT (1) AT376424B (ko)
AU (1) AU526905B2 (ko)
CA (1) CA1155855A (ko)
CH (1) CH653025A5 (ko)
DD (1) DD202149A5 (ko)
DE (1) DE3129309A1 (ko)
DK (1) DK151882C (ko)
ES (3) ES8306367A1 (ko)
FI (1) FI77457C (ko)
FR (1) FR2487348B1 (ko)
GB (3) GB2083810B (ko)
GR (1) GR74590B (ko)
HU (1) HU185682B (ko)
IE (1) IE51427B1 (ko)
IL (1) IL63422A (ko)
IT (1) IT1138110B (ko)
LU (1) LU83512A1 (ko)
NL (1) NL8103536A (ko)
NO (1) NO812558L (ko)
NZ (1) NZ197853A (ko)
PH (1) PH17421A (ko)
PT (1) PT73437B (ko)
SE (1) SE460849B (ko)
YU (3) YU185281A (ko)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689336A (en) * 1981-01-02 1987-08-25 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine 2,4-diones
GR78120B (ko) * 1982-03-01 1984-09-26 Pfizer
US4430337A (en) 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
JPS59186916A (ja) * 1983-04-06 1984-10-23 Aiji Noda 膵石症治療剤
US5130379A (en) * 1988-03-08 1992-07-14 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US4946942A (en) * 1988-03-11 1990-08-07 Bioresearch, Inc. Urethane-protected amino acid-N-carboxyanhydrides
US5442124A (en) * 1989-06-30 1995-08-15 Firmenich Sa Process for the preparation of novel aromatic compounds
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
MC2210A1 (fr) * 1990-06-07 1992-11-26 Wellcome Found Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
GB9017218D0 (en) * 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
KR930701420A (ko) * 1990-08-23 1993-06-11 알렌 제이. 스피겔 혈당저하제로서의 하이드록시우레아 유도체
TW222626B (ko) 1991-07-22 1994-04-21 Pfizer
US5498621A (en) * 1992-05-01 1996-03-12 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5401761A (en) * 1993-12-09 1995-03-28 Pfizer, Inc. Thiazolidinedione hypoglycemic agents
US5925656A (en) * 1995-04-10 1999-07-20 Dr. Reddy's Research Foundation Compounds having antidiabetic, hypolipidemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
GB9604242D0 (en) 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5801173A (en) * 1996-05-06 1998-09-01 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973850B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5889032A (en) * 1996-05-06 1999-03-30 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
AU744518B2 (en) 1996-07-01 2002-02-28 Dr. Reddy's Laboratories Limited Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6114526A (en) 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
CN1325309A (zh) * 1998-08-21 2001-12-05 维洛药品公司 用于治疗或预防病毒感染和相关疾病的化合物、组合物和方法
WO2000018745A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Oxazolidine derivatives for the treatment and prevention of metabolic bone disorders
EP1194146B1 (en) 1999-06-18 2006-07-19 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
CA2377246A1 (en) 1999-06-18 2000-12-28 Ranjit C. Desai Arylthiazolidinedione and aryloxazolidinedione derivatives
AR065670A1 (es) 2007-03-09 2009-06-24 Indigene Pharmaceuticals Inc Combinacion de metformina r-(+) lipoato y agentes antihiperlipidemicos para el tratamiento de hiperglucemia diabetica y complicaciones diabeticas
JP5417860B2 (ja) * 2008-08-26 2014-02-19 住友化学株式会社 α−ヒドロキシエステル類の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE729852C (de) * 1939-07-06 1943-01-04 Carl Nachtigall Verfahren zur Herstellung von 2, 4-Dioxooxazolidinen
US2338220A (en) * 1942-01-31 1944-01-04 Mallinckrodt Chemical Works Process of making oxazolidinediones
US2721197A (en) * 1953-01-05 1955-10-18 Bristol Lab Inc Bicyclic lactams
US2961377A (en) * 1957-08-05 1960-11-22 Us Vitamin Pharm Corp Oral anti-diabetic compositions and methods
FR1284516A (fr) * 1957-11-20 1962-02-16 France Etat Produits utilisables notamment comme agents susceptibles d'agir sur la croissance des plantes et leur procédé de fabrication
GB1227428A (ko) * 1968-04-08 1971-04-07
US3699229A (en) * 1970-12-18 1972-10-17 Abbott Lab 2-oxo-5-phenyl-4-oxazolidinone as an anti-depressant agent
AT322266B (de) * 1972-11-06 1975-05-12 Rath Karl Friedrich Vorrichtung zum einsetzen von pflanzen
FR2207706B1 (ko) * 1972-11-24 1975-11-28 Orsymonde
DE2813873A1 (de) * 1978-03-31 1979-10-11 Basf Ag Verfahren zur herstellung von oxazolidin-2,4-dionen
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones

Also Published As

Publication number Publication date
AR231721A1 (es) 1985-02-28
AR228061A1 (es) 1983-01-14
ES8306132A1 (es) 1983-05-01
KR850000382B1 (ko) 1985-03-23
GB8317144D0 (en) 1983-07-27
DE3129309A1 (de) 1982-03-18
HU185682B (en) 1985-03-28
PT73437B (en) 1983-09-01
ATA328681A (de) 1984-04-15
FI77457B (fi) 1988-11-30
GB2132609A (en) 1984-07-11
ES514666A0 (es) 1983-05-01
DK151882C (da) 1988-06-06
NO812558L (no) 1982-01-29
AR230834A1 (es) 1984-07-31
DE3129309C2 (ko) 1987-06-19
FI812340L (fi) 1982-01-29
GB2128987B (en) 1984-09-26
FR2487348A1 (fr) 1982-01-29
IE51427B1 (en) 1986-12-24
IL63422A (en) 1984-11-30
GB8317145D0 (en) 1983-07-27
KR850000387B1 (ko) 1985-03-25
CA1155855A (en) 1983-10-25
GB2132609B (en) 1985-01-03
AU526905B2 (en) 1983-02-03
ES514665A0 (es) 1983-05-01
ES504322A0 (es) 1983-05-16
GB2083810A (en) 1982-03-31
YU88283A (en) 1983-12-31
GB2128987A (en) 1984-05-10
NZ197853A (en) 1986-09-10
IE811695L (en) 1982-01-28
LU83512A1 (fr) 1982-02-17
KR830006247A (ko) 1983-09-20
PT73437A (en) 1981-08-01
ES8306367A1 (es) 1983-05-16
YU88183A (en) 1983-12-31
AT376424B (de) 1984-11-26
DK151882B (da) 1988-01-11
KR850000381B1 (ko) 1985-03-23
DK334681A (da) 1982-03-05
IL63422A0 (en) 1981-10-30
FR2487348B1 (fr) 1986-05-02
DD202149A5 (de) 1983-08-31
FI77457C (fi) 1989-03-10
PH17421A (en) 1984-08-08
IT8123175A0 (it) 1981-07-27
GR74590B (ko) 1984-06-29
YU185281A (en) 1983-12-31
SE460849B (sv) 1989-11-27
IT1138110B (it) 1986-09-17
ES8306133A1 (es) 1983-05-01
CH653025A5 (fr) 1985-12-13
KR850003291A (ko) 1985-06-13
GB2083810B (en) 1984-03-14
NL8103536A (nl) 1982-02-16
SE8104542L (sv) 1982-01-29
US4367234A (en) 1983-01-04

Similar Documents

Publication Publication Date Title
KR850003291A (ko) 5-치환된 옥사졸리딘-2, 4-디온의 제조방법
ES520637A0 (es) Metodo de preparar compuestos carbostirilicos.
NO811843L (no) Heterocykliske forbindelser.
DK301180A (da) Fremgangsmaade til fremstilling af 5-substituerede 2,3-diarylthiophener
IT7824577A0 (it) Metodo per la produzione di anticorpi.
DK143491A (da) Fremgangsmaade til fremstilling af 3-oen-phenylacetylaminopiperidinaa-2,6-dion
NO154882C (no) Fremgangsmaate for fremstilling av 2-(2-(1,4-benzodioksanyl)) -2-imidazolin.
DE3177276D1 (de) Monoklonale antikoerper.
YU185481A (en) Process for obtaining hypoglcemic 5-substituted oxazolidine-2,4-diones
KR850002011A (ko) 헤테로사이클릭 화합물의 제조방법
DK153181A (da) Fremgangsmaade til fremstilling af 3-pyrrolin-2,5-dioner
DK370781A (da) Fremgangsmaade til fremstilling af 3,4-bis-phenyl-1,2,4-triazoler
BE888392A (fr) Lentille pour implantation intre-oculaire,
FI73925B (fi) Styrsystem foer fordon.
KR850003307A (ko) 5-치환된 옥사졸리딘-2, 4-디온의 제조방법
DK294981A (da) Fremgangsmaade til fremstilling af 1,2,4-triazol.
BE888252A (fr) Thiazoles,
DK513580A (da) Fremgangsmaade til fremstilling af 4,5-diaryl-alfa (polyhalogenalkyl)-1h-imidazol-2-methanoler
DK26881A (da) Fremgangsmaade til fremstilling af alfaketocarboxylsyre-n-tert. butylamider
DE3165028D1 (de) Triazaloquinoxalin-1,4-diones
DK575081A (da) Fremgangsmaade til fremstilling af 5-(pyridinyl-)-benzimidazol
DK160431C (da) Analogifremgangsmaade til fremstilling af 11beta-methyl-17beta-hydroxy-17alpha-methyl-estra-4,9-dien-3-on
ES521596A0 (es) Metodo de preparar compuestos piridotienopiridacinicos.
ES512697A0 (es) "metodo de preparar compuestos metilquinoxalin-1,4-dioxidicos".
MX9046A (es) Metodo para producir cefalosporinas.

Legal Events

Date Code Title Description
A107 Divisional application of patent
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 19900124

Year of fee payment: 6

LAPS Lapse due to unpaid annual fee