DK146762C - Analogifremgangsmaade til fremstilling af 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridin-5-carboxylsyreisobutylester - Google Patents

Analogifremgangsmaade til fremstilling af 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridin-5-carboxylsyreisobutylester

Info

Publication number
DK146762C
DK146762C DK498476A DK498476A DK146762C DK 146762 C DK146762 C DK 146762C DK 498476 A DK498476 A DK 498476A DK 498476 A DK498476 A DK 498476A DK 146762 C DK146762 C DK 146762C
Authority
DK
Denmark
Prior art keywords
dihydropyridine
methoxycarbonyl
nitrophenyl
dimethyl
preparation
Prior art date
Application number
DK498476A
Other languages
Danish (da)
English (en)
Other versions
DK146762B (da
DK498476A (da
Inventor
Egbert Wehinger
Friedrich Bossert
Arend Heise
Stanislav Kazda
Kurt Stoepel
Wulf Vater
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK498476A publication Critical patent/DK498476A/da
Publication of DK146762B publication Critical patent/DK146762B/da
Application granted granted Critical
Publication of DK146762C publication Critical patent/DK146762C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK498476A 1975-11-05 1976-11-04 Analogifremgangsmaade til fremstilling af 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridin-5-carboxylsyreisobutylester DK146762C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2549568A DE2549568C3 (de) 1975-11-05 1975-11-05 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DE2549568 1975-11-05

Publications (3)

Publication Number Publication Date
DK498476A DK498476A (da) 1977-05-06
DK146762B DK146762B (da) 1983-12-27
DK146762C true DK146762C (da) 1984-06-12

Family

ID=5960951

Family Applications (1)

Application Number Title Priority Date Filing Date
DK498476A DK146762C (da) 1975-11-05 1976-11-04 Analogifremgangsmaade til fremstilling af 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridin-5-carboxylsyreisobutylester

Country Status (27)

Country Link
JP (1) JPS5259161A (no)
AT (1) AT352129B (no)
AU (1) AU498964B2 (no)
BE (1) BE847968A (no)
BG (6) BG25078A3 (no)
CA (1) CA1085406A (no)
CH (2) CH623038A5 (no)
CS (1) CS200499B2 (no)
DE (1) DE2549568C3 (no)
DK (1) DK146762C (no)
ES (2) ES452986A1 (no)
FI (1) FI60704C (no)
FR (1) FR2330395A1 (no)
GB (1) GB1516793A (no)
GR (1) GR61241B (no)
HK (1) HK12681A (no)
IE (1) IE43984B1 (no)
IL (1) IL50817A (no)
LU (2) LU88275I2 (no)
NL (2) NL175915C (no)
NO (1) NO145574C (no)
NZ (1) NZ182502A (no)
PL (2) PL106084B1 (no)
PT (1) PT65797B (no)
RO (1) RO70295A (no)
SE (1) SE423542B (no)
ZA (1) ZA766622B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
JPS5982192U (ja) * 1982-11-27 1984-06-02 エムケ−精工株式会社
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
DE2549568A1 (de) 1977-05-18
CH623038A5 (en) 1981-05-15
NL930035I2 (nl) 1993-10-01
SE423542B (sv) 1982-05-10
DE2549568B2 (de) 1980-08-21
BG25078A3 (en) 1978-07-12
BG24805A3 (en) 1978-05-12
AU498964B2 (en) 1979-03-29
ES452986A1 (es) 1977-12-16
FI60704B (fi) 1981-11-30
GB1516793A (en) 1978-07-05
SE7612308L (sv) 1977-05-06
BG25079A3 (en) 1978-07-12
LU76133A1 (no) 1977-06-02
CH622779A5 (en) 1981-04-30
JPS5259161A (en) 1977-05-16
BG24804A3 (en) 1978-05-12
CS200499B2 (en) 1980-09-15
PT65797B (de) 1978-05-12
BG24803A3 (en) 1978-05-12
PL105940B1 (pl) 1979-11-30
AU1935876A (en) 1978-05-11
NO145574C (no) 1982-04-21
NZ182502A (en) 1978-07-28
DK146762B (da) 1983-12-27
BG24668A3 (en) 1978-04-12
IE43984B1 (en) 1981-07-15
LU88275I2 (no) 1994-02-03
CA1085406A (en) 1980-09-09
GR61241B (en) 1978-10-12
NL930035I1 (nl) 1993-08-02
DK498476A (da) 1977-05-06
NL7612198A (nl) 1977-05-09
ZA766622B (en) 1977-10-26
PL106084B1 (pl) 1979-11-30
FR2330395B1 (no) 1978-12-22
PT65797A (de) 1976-12-01
NO763608L (no) 1977-05-06
DE2549568C3 (de) 1981-10-29
AT352129B (de) 1979-09-10
ES463166A1 (es) 1978-07-16
NO145574B (no) 1982-01-11
HK12681A (en) 1981-04-10
BE847968A (fr) 1977-05-04
IL50817A0 (en) 1977-01-31
ATA814276A (de) 1979-02-15
IE43984L (en) 1977-05-05
NL175915C (nl) 1985-01-16
IL50817A (en) 1979-07-25
FR2330395A1 (fr) 1977-06-03
JPS5647185B2 (no) 1981-11-07
RO70295A (ro) 1981-08-17
FI60704C (fi) 1982-03-10
FI763160A (no) 1977-05-06

Similar Documents

Publication Publication Date Title
DK146626C (da) Analogifremgangsmaade til fremstilling af 4'-deoxydaunomycin
DK424476A (da) Fremgangsmade til fremstilling af svovlholdige organosiliciumforbindelser
DK148907C (da) Analogifremgangsmaade til fremstilling af dihydrocyclosporin c
DK59077A (da) Fremgangsmade til fremstilling af hidtil ukendte carboxyalkylacylaminosyrer
DK129477A (da) Fremgangsmade til fremstilling af alkyloximderivater af 7-aminothiazolylacetamidocephalosporansyre
DK282076A (da) Fremgangsmade til fremstilling af 2,3-dihydro6,7-disubstitueret-5-acyl-benzofuran-2-carboxylsyrer
DK23677A (da) Fremgangsmade til fremstilling af oximderivater af 7-aminothiazolyl-acetamidocephalosporansyre
DK149773C (da) Analogifremgangsmaade til fremstilling af 3-quinolincarboxylsyrederivater
SE425783B (sv) Analogiforfarande for framstellning av lysergsyraamider
DK470376A (da) Fremgangsmade til fremstilling af phenoxyalcarboxylsyrer
DK156661C (da) Analogifremgangsmaade til fremstilling af 1-azaxanton-3-karboxylsyrer
DK226476A (da) Fremgangsmade til fremstilling af propargyl-2-phenylamino-imidazoliner-(2) eller syreadditionssalte heraf
DK146762C (da) Analogifremgangsmaade til fremstilling af 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridin-5-carboxylsyreisobutylester
DK12477A (da) Fremgangsmade til fremstilling af 7-aminothiazolylacetamidocephalosporansyrederivater
DK148139C (da) Analogifremgangsmaade til fremstilling af 5-benzyl-2-oxazolidonderivater
DK386876A (da) Fremgangsmade til fremstilling af n-tetrahydrofurfuryl-noroxymorphoner eller syreadditionssalte deraf
DK139522C (da) Analogifremgangsmaade til fremstilling af 9-iminoalkylamino-erythromyciner eller syreadditionssalte deraf
DK362676A (da) Fremgangsmade til fremstilling af 1,4-dihydropyridiner
DK143757C (da) Analogifremgangsmaade til fremstilling af 16,16-disubstituerede 3-oxoandrostener
DK153176A (da) Fremgangsmade til fremstilling af fenylpropionsyrer
DK369677A (da) Fremgangsmaade til fremstilling af oximderivater af 3-carbamoyloxymethyl-7-aminothiazolylacetamidocephalosponsyre
DK146629C (da) Analogifremgangsmaade til fremstilling af depotsteroidestere
DK247976A (da) Fremgangsmade til fremstilling af quinolin-3-carboxylsyrer
DK406976A (da) Fremgangsmade til fremstilling af carboxylgruppeholdige organiske phosphorforbindelser
DK484676A (da) Fremgangsmade til fremstilling af aroyl-phenyliden- eller aroyl-phenylnaphthalenforbindelser

Legal Events

Date Code Title Description
PUP Patent expired