BG24804A3 - Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid - Google Patents

Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid

Info

Publication number
BG24804A3
BG24804A3 BG035344A BG3534476A BG24804A3 BG 24804 A3 BG24804 A3 BG 24804A3 BG 035344 A BG035344 A BG 035344A BG 3534476 A BG3534476 A BG 3534476A BG 24804 A3 BG24804 A3 BG 24804A3
Authority
BG
Bulgaria
Prior art keywords
dihydropyridiny
methoxycarbonyl
nitrophenyl
dimethyl
obtaining
Prior art date
Application number
BG035344A
Other languages
Bulgarian (bg)
English (en)
Inventor
Egbert Wehinger
Friedrich Bossert
Arend Heise
Stanislav Kazda
Kurt Stoepel
Wulf Vater
Original Assignee
Неизвестен
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Неизвестен filed Critical Неизвестен
Publication of BG24804A3 publication Critical patent/BG24804A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG035344A 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid BG24804A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2549568A DE2549568C3 (de) 1975-11-05 1975-11-05 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BG24804A3 true BG24804A3 (en) 1978-05-12

Family

ID=5960951

Family Applications (6)

Application Number Title Priority Date Filing Date
BG035341A BG25078A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035345A BG24805A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG034575A BG24668A3 (en) 1975-11-05 1976-11-01 Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid
BG035342A BG25079A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035343A BG24803A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG035344A BG24804A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid

Family Applications Before (5)

Application Number Title Priority Date Filing Date
BG035341A BG25078A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035345A BG24805A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG034575A BG24668A3 (en) 1975-11-05 1976-11-01 Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid
BG035342A BG25079A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG035343A BG24803A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid

Country Status (27)

Country Link
JP (1) JPS5259161A (xx)
AT (1) AT352129B (xx)
AU (1) AU498964B2 (xx)
BE (1) BE847968A (xx)
BG (6) BG25078A3 (xx)
CA (1) CA1085406A (xx)
CH (2) CH623038A5 (xx)
CS (1) CS200499B2 (xx)
DE (1) DE2549568C3 (xx)
DK (1) DK146762C (xx)
ES (2) ES452986A1 (xx)
FI (1) FI60704C (xx)
FR (1) FR2330395A1 (xx)
GB (1) GB1516793A (xx)
GR (1) GR61241B (xx)
HK (1) HK12681A (xx)
IE (1) IE43984B1 (xx)
IL (1) IL50817A (xx)
LU (2) LU76133A1 (xx)
NL (2) NL175915C (xx)
NO (1) NO145574C (xx)
NZ (1) NZ182502A (xx)
PL (2) PL105940B1 (xx)
PT (1) PT65797B (xx)
RO (1) RO70295A (xx)
SE (1) SE423542B (xx)
ZA (1) ZA766622B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
JPS5982192U (ja) * 1982-11-27 1984-06-02 エムケ−精工株式会社 扉
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
DE2549568A1 (de) 1977-05-18
IE43984L (en) 1977-05-05
PT65797B (de) 1978-05-12
AU1935876A (en) 1978-05-11
BG24805A3 (en) 1978-05-12
DE2549568C3 (de) 1981-10-29
AT352129B (de) 1979-09-10
ATA814276A (de) 1979-02-15
HK12681A (en) 1981-04-10
FI60704C (fi) 1982-03-10
GB1516793A (en) 1978-07-05
SE7612308L (sv) 1977-05-06
NO145574B (no) 1982-01-11
DK146762B (da) 1983-12-27
NO145574C (no) 1982-04-21
FI60704B (fi) 1981-11-30
FI763160A (xx) 1977-05-06
LU76133A1 (xx) 1977-06-02
BE847968A (fr) 1977-05-04
SE423542B (sv) 1982-05-10
BG24668A3 (en) 1978-04-12
IL50817A (en) 1979-07-25
JPS5647185B2 (xx) 1981-11-07
NL930035I1 (nl) 1993-08-02
PL106084B1 (pl) 1979-11-30
CH623038A5 (en) 1981-05-15
PT65797A (de) 1976-12-01
NO763608L (xx) 1977-05-06
GR61241B (en) 1978-10-12
NL175915C (nl) 1985-01-16
FR2330395B1 (xx) 1978-12-22
JPS5259161A (en) 1977-05-16
BG24803A3 (en) 1978-05-12
CA1085406A (en) 1980-09-09
ZA766622B (en) 1977-10-26
IE43984B1 (en) 1981-07-15
BG25078A3 (en) 1978-07-12
NZ182502A (en) 1978-07-28
CS200499B2 (en) 1980-09-15
IL50817A0 (en) 1977-01-31
PL105940B1 (pl) 1979-11-30
DE2549568B2 (de) 1980-08-21
BG25079A3 (en) 1978-07-12
ES452986A1 (es) 1977-12-16
DK146762C (da) 1984-06-12
NL7612198A (nl) 1977-05-09
AU498964B2 (en) 1979-03-29
FR2330395A1 (fr) 1977-06-03
DK498476A (da) 1977-05-06
NL930035I2 (nl) 1993-10-01
RO70295A (ro) 1981-08-17
ES463166A1 (es) 1978-07-16
LU88275I2 (xx) 1994-02-03
CH622779A5 (en) 1981-04-30

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